| Title | Description | Published | Added |
| A surgeon remembers | | 1953 | 2023-12-22T18:53:56Z |
| Authenticom, Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-03-25T23:18:28Z |
| The pageant of Japanese history, | | 1938 | 2023-07-28T12:19:13Z |
| le mouvement baptiste en palestine et syrie | | 1935 | 2025-06-16T22:29:54Z |
| the new testament | | 1937 | 2025-06-17T00:05:16Z |
| Mannen Med Salgpiporna | | 1960 | 2025-09-26T02:02:52Z |
| Leibniz | | 1953 | 2025-09-26T03:41:58Z |
| Education and society in modern Germany | | 1949 | 2023-07-25T04:04:04Z |
| Research in physiology | | 1971 | 2025-09-08T00:26:07Z |
| Scientists In Organizations | | 1966 | 2025-09-11T18:21:23Z |
| De Racine Au Parthenon: Essais Sur La Litterature Et L'Art A L'age Classique | | 1977 | 2025-09-04T14:43:38Z |
| George G. Manderbach, Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2024-07-16T09:08:36Z |
| Separation - Invuduation | | 1971 | 2025-09-08T02:57:52Z |
| CDK Global, LLC v. Southeast Atlantic Peterbilt of North Carolina, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2018-09-30T20:14:22Z |
| le bapteme et la confirmation | | 1969 | 2025-06-16T09:29:09Z |
| the valaue theory of karl marx | | 1976 | 2025-05-22T13:48:47Z |
| Flight Without Power | | 1940 | 2025-09-12T12:32:24Z |
| East McComb Body Shop v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2024-08-28T09:13:51Z |
| From this day forward | | 1941 | 2023-07-29T05:57:44Z |
| yahoo-groups-2018-07-21T22-47-06Z-4bbc23 | Yahoo! Groups API grab. Contains messages of the following groups: 1ahoahong 2009cmsc128 abajarcolesterol abqphilosophers aceng1-ib agentorangeveterans alumnisaba93 ap12thv1 apn_maamvanne aquascape-indonesia arabic_inside arkiyoliji1 artsbabes asteric_of_smpn4_bogor ba186_sad bch_tongdoan_2008_2010 beginnerbluegrassjam biblebeegurnee binjakon bits_dlpd_msss2009 blogbirudotcom bsa_bag bspe1-1_economist ca411-1m canoepolohunks0809 ccfcommittee_09_10 che_141_142_tqruv chem2a_woodland cict_itfnds-icb citihi85 contratoscinemauff cool_hood_babii cpi_2009_2010 csci12_tz curriculoseprogramas2009essb dbti_tarlac_faculty discretemath_it2nd dmt_people dnyandeepnews dpms_2010 ec102h eco101_09 eco11_0910 ecoprofessionals_nea edp111_addu elladerma emc_ss_dames encoreestate esjsem1admu0910 galeradoingles2008 genevaacademicfoundation glawenko h-383lpu hau_6comgrad hiltech_group homplantes hum1_thu1 iit-kgp-met75 imtak-05 infoamie ingenieria_gay inspirationaldesignsvoices irc-sbg ironbros-team_one it10; | | 2018-07-21T22:47:14Z |
| The Future of Public Access TV and The Internet | Mark Cooper of the Consumer Federation of America speaks with local independent radio host John Grebe about current bills in Congress affecting the future of Public Access Television and the Internet. We also hear from Jason Crow, Access Coordinator of Cambridge Community Television and Michael Eisenmenger of Manhattan Neighborhood Network about how pending legislation in Congress takes away local control of media and places more power in the hands of Big Cable and Telephone companies. Click here to listen to the ACMEBoston Podcast February 11, 2006. Also discussed is the issue of Network Neutrality which Free Press , the national media reform organization, describes as "the guiding principle of the Internet that fosters open competition and innovation, while preserving the independence and accessibility of the World Wide Web" - Free Press, Net Freedom Now . To take a closer look at these issues, we'll hear John Grebe's interview from his program, "Sounds of Dissent" broadcast live on ; | 2006 | 2006-07-27T08:21:29Z |
| Aktu 20.05.1 | Toute l'aKtualité de Kubernetes en français. https://github.com/p7t/actus https://github.com/goharbor/harbor/releases/tag/v2.0.0 https://github.com/kubernetes-sigs/kind/releases/tag/v0.8.0 https://cdk8s.io/ https://github.com/ahmetb/kubectx/releases/tag/v0.9.0 | 2020 | 2020-05-20T10:34:03Z |
| At-home dumbbell workout - Seated Curls | | 2020 | 2022-08-11T20:02:13Z |
| Nutrient limitations alter cell division control and chromosome segregation through growth-related kinases and phosphatases. | This article is from Philosophical Transactions of the Royal Society B: Biological Sciences , volume 366 . Abstract In dividing fission yeast Schizosaccharomyces pombe cells, the balance between Wee1 kinase and Cdc25 phosphatase which control the cyclin-dependent kinase (CDK) at the G2–M transition determines the rod-shaped cell length. Under nitrogen source starvation or glucose limitation, however, cell size determination is considerably modulated, and cell size shortening occurs for wild-type cells. For several mutants of kinases or phosphatases, including CDK, target of rapamycin complex (TORC) 1 and 2, stress-responsive mitogen-activated protein kinase (MAPK) Sty1/Spc1, MAPK kinase Wis1, calcium- and calmodulin-dependent protein kinase kinase-like Ssp1, and type 2A and 2A-related phosphatases inhibitor Sds23, this cell shortening does not normally occur. In tor1 and ssp1 mutants, cell elongation is observed. Sds23 that binds to and inhibits 2A and 2A-related phosphatases is syne; | 2011 | 2014-10-27T03:15:22Z |
| Re-thinking cell cycle regulators: the cross-talk with metabolism. | This article is from Frontiers in Oncology , volume 3 . Abstract Analysis of genetically engineered mice deficient in cell cycle regulators, including E2F1, cdk4, and pRB, showed that the major phenotypes are metabolic perturbations. These key cell cycle regulators contribute to lipid synthesis, glucose production, insulin secretion, and glycolytic metabolism. It has been shown that deregulation of these pathways can lead to metabolic perturbations and related metabolic diseases, such as obesity and type II diabetes. The cyclin–cdk–Rb–E2F1 pathway regulates adipogenesis in addition to its well-described roles in cell cycle regulation and cancer. It was also shown that E2F1 directly participates in the regulation of pancreatic growth and function. Similarly, cyclin D3, cdk4, and cdk9 are also adipogenic factors with strong effects on whole organism metabolism. These examples support the emerging notion that cell cycle regulatory proteins also modulate metabolic processes. These ce; | 2013 | 2014-10-28T16:47:52Z |
| Molecular mechanisms of anti-tumor properties of P276-00 in head and neck squamous cell carcinoma. | This article is from Journal of Translational Medicine , volume 11 . Abstract Background: Tumors of the head and neck present aggressive pathological behavior in patients due to high expression of CDK/CCND1 proteins. P276-00, a novel CDK inhibitor currently being tested in clinic, inhibits growth of several cancers in vitro and in vivo. The pre clinical activity of P276-00 in head and neck cancer and its potential mechanisms of action at molecular level are the focus of the current studies. Method: We have investigated the anti-cancer activity of P276-00 in head and neck tumors in vitro and in vivo. Candidate gene expression profiling and cell based proteomic approaches were taken to understand the pathways affected by P276-00 treatment. Results: It was observed that P276-00 is cytotoxic across various HNSCC cell lines with an IC50 ranging from 1.0-1.5 μmoles/L and culminated in significant cell-cycle arrest in G1/S phase followed by apoptosis. P276-00 treatment suppressed cell prolif; | 2013 | 2014-10-24T19:52:55Z |
| Particled Mica, STB-HO has chemopreventive potential via G1 arrest, and inhibition of proliferation and vascular endothelial growth factor receptor 2 in HCT colorectal cancer cells. | This article is from BMC Complementary and Alternative Medicine , volume 13 . Abstract Background: Though Mica, a thin and sheet like mineral, has been used as a mineral medicine for treatment of bleeding, dysentery and inflammation in traditional medicine including Ayurveda, the biological evidences of Mica were not clearly elucidated so far. Thus, in the present study, the antitumor mechanism of particled Mica (STB-HO) was examined in colorectal cancers. Methods: Athymic nude mice were inoculated with HCT116 colon cancer cells and orally administered STB-HO daily for 41 days, and HCT116 and human umbilical vein endothelial cells (HUVECs) were treated with STB-HO for 0 ~ 24 hours to perform immunoblotting, cytotoxicity assay, FACs analysis and measurement of matrix metalloproteinase 9 (MMP-9) secretion and other experiments. Significant differences of all date were evaluated using Student’s t-test and a Turkey-Kramer multiple-comparison post test. Results: STB-HO significantly; | 2013 | 2014-10-25T04:28:02Z |
| The arginine methyltransferase PRMT6 regulates cell proliferation and senescence through transcriptional repression of tumor suppressor genes. | This article is from Nucleic Acids Research , volume 40 . Abstract The protein arginine methyltransferase 6 (PRMT6) is a coregulator of gene expression and executes its repressing as well as activating function by asymmetric dimethylation of histone H3 at R2 (H3 R2me2a). Given that elevated expression levels of PRMT6 have been reported in various cancer types, we explore here its role in cell proliferation and senescence. We find that knockdown of PRMT6 results in proliferation defects of transformed as well as non-transformed cells, causes G1-phase arrest and induces senescence. This phenotype is accompanied by transcriptional upregulation of important cell cycle regulators, most prominently the cyclin-dependent kinase (CDK) inhibitor gene p21 (p21CIP1/WAF1, CDKN1A) and p16 (p16INK4A, CDKN2A). Chromatin immuno-precipitation analysis reveals that the p21 gene is a direct target of PRMT6 and the corresponding histone mark H3 R2me2a. Using a cell model of oncogene-induced senescence (OIS; | 2012 | 2014-10-28T05:36:50Z |
| [CDK 063] The Tin Foil Hat Brigade - Serious Musician | Unrequited love, the frustrations of modern life, Scallies shouting abuse at women from cars - The Tin Foil Hat Brigade talks about these, and more - all within a ten-minute blast of furious Game Boy noise and raw, emotional vocals. Or something like that, anyway. All Music and Lyrics by The Tin Foil Hat Brigade. Recorded and Mastered by Lloyd Gabriel. Additional Vocals (on G.Y.R.O) by Simon Patrick Gabriel and Lloyd Gabriel. Artwork and Photography by Simon Thelwell - http://www.sixeightthree.com/ | 2014 | 2020-01-09T22:58:35Z |
| Shadow of Fu Manchu, | | 1948 | 2023-07-25T02:48:30Z |
| Die Russen | | 1976 | 2025-09-08T18:17:06Z |
| CDK-US - O&O S.r.l. | | | 2021-04-07T20:38:29Z |
| [CDK 012] Spurs Of A Dead Ranger | YEEE-HAW! Sparkyboy , possibly South Africa’s only chipartist, has unleashed this heaven for us – It’s one of the more unique releases out there, utilising everything from Game Boys to his toy guitar collection! I’m loving it all at the moment, especially ‘Gloom’ – what an opener! | 2008 | 2019-12-06T22:32:39Z |
| DTIC ADA316821: Cellular Proteins Interacting with the Tumor Suppressor Protein p53. | Tumor suppressor protein p53 interacts directly with the DNA replication factor RPA and inhibits its ability to bind single-strand-DNA. We defined the domain of p53 that bound to RPA and constructed p53 mutants that failed to bind RPA, but still functioned as transcriptional activators. We found that while these mutants of p53 lost their ability to bind RPA; they still maintained the growth suppression function of p53. Growth suppression function of p53 is dependent on its transactivation activity, probably by inducing p21 and other cell cycle inhibitors. We have extended our study to the p2l protein, which is induced by p53 and interacts with both the cdk2 Icinase and a DNA replication factor PcNA. Here we have demonstrated the importance of PCNA-inhibitory domain of p21 in vivo. We have also shown that p21 has to interact directly with both cyclin subunit and cdk2 subunit of the cyclin-cdk complex in order to inhibit the kinase activity and suppress cell growth in vivo. | 1996 | 2018-04-03T17:57:56Z |
| Video Editing Pc | Ultimate Editing & Rendering Workstation Engineered for professional video editors, content creators, and motion designers who demand smooth timelines, fast exports, and reliable rendering performance. This CDK build is optimized to handle 4K / 8K video workflows, complex timelines, and simultaneous editing + rendering without slowdowns. Supported Professional Software Adobe Premiere Pro | After Effects | DaVinci Resolve | Blender | Cinema 4D | Adobe Illustrator | Adobe Audition | Figma | Adobe XD Performance Advantages • Smooth playback for complex 4K / 8K timelines • Faster rendering and export performance • Stable operation during long editing sessions • Efficient multitasking for editing, compositing, and rendering Not just a PC. A workstation built for creative production pipelines. CDK — Powering Tomorrow’s Workstations. 📞 +91 92707 66589 🌐 www.designsbykira.in #CDKWorkstations #VideoEditingPC #ContentCreatorSetup | | 2026-04-07T09:46:14Z |
| DTIC ADA359281: Role of the Cdk Inhibitor Sic 1 in Start | Mpst cells have four fundamental goals; they must replicate their DNA, segregate their chromosomes, double their mass, and divide. Coordination of these events is essential. I have used the budding yeast S. cerevisiae to dissect the molecular events that control cell cycle progression. I have shown that not only are G1 cyclin-CDK complexes highly unstable rate-limiting activators for cell cycle progression, but that their essential function is to regulate the initiation of DNA replication by phosphorylating and promoting the degradation of a key cell cycle inhibitor, Sic1 (1,2). In fact, cyclin-CDK-regulated proteolysis may constitute the major mechanism of cell cycle control (3). Moreover, Sic1 appears to be the analog of the RB tumor suppressor gene. I have shown that Sic1, like RB, controls the timing of S-phase, ensures genomic stability, and most significantly, sic1 deletions, like rb deletions, completely remove cell cycle dependence on G1 cyclins (1,22). Furthermore, Sic1 protei; | 1998 | 2018-04-21T20:11:43Z |
| CKD (28648) | CDK logo | 2012 | 2021-04-02T02:54:24Z |
| Spagnoli v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2024-04-26T09:11:10Z |
| DTIC ADA435854: The Role of Ubiquitin E3 Ligase SCFSKP2 in Prostate Cancer Development | The CDK inhibitor p27Kipl acts as a negative regulator in the cell cycle and in prostate tumorigenesis. Either the loss of p27 or over-expression of its key regulator ubiquitin E3 ligase SKP2 is associated with prostate cancer. Prostate-sepcific expression of SKP2 is sufficient to induce hyperplasia, displasia, and low grade carcinoma in the mouse prostate gland. We propose to examine whether SKP2 cooperates with or is regulated by tumor suppressors such as Pten or Nkx3.1 implicated in prostatic tumorigenesis. In the past year, we have initiated the experiments by breeding and expansion of the colonies, crossing the SKP2 transgenic mice into Pten +/- strains, and ordering Nkx3.1 mice. Compound mice of SKP2 transgene and Pten +/- were made. Our initial studies suggest that there i&. no substantial difference in tumor frequency and grade in the SKP2 and Pten +/- compound mice versus single genetic alterations. These results suggest that PTEN may act through SKP2 for tumorigenesis. Since ; | 2005 | 2018-05-27T08:46:56Z |
| DTIC ADA455296: Consequences of Cyclin D1/BRCA1 Interaction in Breast Cancer Progression | The inheritance of one defective BRCA1 or BRCA2 allele predisposes an individual to developing breast, ovarian and T-cell cancers. In addition, in breast cancers where BRCA1 is not mutated, it is often functionally inactivated. Furthermore, cyclin D1 has been shown to be overexpressed in many cancers including breast cancer and its associates with BRCA1. Because of the crucial role of both of these proteins in cancer, it is reasonable to expect that this interaction has a significant role in tumor cells. The understanding of when this interaction occurs during cell cycle progression will help to determine the role of cyclin D1/BRCA1 binding in breast cancer cells. Therefore, I hypothesize that the direct interaction of cyclin D1 with BRCA1 results in the cell cycle dependent regulation of the activity of BRCA1. In this study, I wish to identify and confirm the cell cycle dependent cyclin D1/BRCA1 interaction in breast cancer cells, determine the biochemical consequence of cyclin D1/BRC; | 2006 | 2018-06-07T00:13:22Z |
| DTIC ADA378108: Role of the Cdk Inhibitor Sic 1 in Start | Nearly 180,000 women will develop breast cancer in 1999 and 44,000 will die. Cancer is essentially a disease of inappropriate proliferation due to a loss of normal cell cycle controls. We study cell cycle controls in the budding yeast S. cerevisiae. We have shown that the formation of active G1-cyclin dependent kinase complexes (Cdks) is rate limiting for cell cycle progression. The activity of these complexes is regulated through their association with highly unstable G1 cyclins. G1 cyclins are constitutively unstable, and their only essential function is to phosphorylate the B-type Cdk inhibitor, Sic1, and target it for degradation. Sic1 is one of few known in vivo substrates of yeast G1-Cdks. The amount and phosphorylation state of Sic1 appears to determine the timing and size of cell division. Sic1 mutants lacking several phosphorylation sites are stabilized and completely block cell cycle progression. Thus, the phosphorylation and subsequent degradation of Sic1 appears to be the c; | 1999 | 2018-04-28T13:18:00Z |
| Laraqua's Masks Of Nyarlathotep Prologue | The prologue for my Masks of Nyarlathotep solo game designed to get the protagonist to New York ready for the Half-Moon Cult adventure followed by Masks itself. More information on the campaign can be found, including Easter Eggs during the various sessions and a little context, can be found under the Masks of Nyarlathotep tag on http://stwildonroleplaying.blogspot.com.au/ The opening music is CDK's Sunday Sunrise which is Creative Commons (Attribution 3.0) and can be found at http://ccmixter.org/files/cdk/13613 Episode 3's subway soundtrack is Public Domain material which can be found at the Soundbible at http://soundbible.com/386-Riding-NYC-Subway-Car.html | 2013 | 2013-11-24T21:58:36Z |
| IUMA: ballantine skuadra | Todo Partio por el año 98', cuando se conocieron Knowman y Black Market. Paso el tiempo y fueron formando distintos grupos (BLG, AGS, CDK), hasta que el 2002 dieron en el clavo creando la BALLANTINE'SKUADRA (un poco en broma, un poco en realidad), con el tiempo fue tomando fuerza e integrando a mas personajes. Un "gancho" en esa creación fue God Killah quien tenia una larga amistad con Get Killah, y este con Dj Killah. Al mismo tiempo otra amistad de antaño es la de God Killah y Glace one, lo que facilito la union entre todos (God Killah conocio hace muchos años a Black Market jejeje.). Get Killah con God Killah, hicieron el primer tema con el respaldo de Dj Killah. Se fueron creando distintas formulas, muchas practicas, todo para obtener el sonido que tenemos. La BTS como cada uno tubo un "comenzar" diferente, tienen muchos estilos y muchas influencias, esta mescla es la que le da el "toque". Los estudios son Black Label Studios a cargo de Dj Killah y la colaboración de los demas; | | 2012-05-16T19:45:45Z |
| DTIC ADA474451: Mechanism of Antineoplastic Action of Bisperoxovanadium Compound | This work describes studies into the mechanism of action of bisperoxovanadium (bpVs) compounds and into the basic biology and regulation of Cdc25A phosphatase. The bpVs cause phase-specific cell cycle arrest (G1/S), dose-dependent inhibition of Cdk activity, and persistent Rb hypophosphorylation upon release from serum starvation, consistent with Cdc25A inhibition. Further, they cause p53-independent apoptosis. Oxidative stress and DNA damage do not appear to be involved in their mechanism of action, given that: p53 is not induced by bpV(Me2Phen); p53 and p21 status do not affect IC50; depletion of glutathione or supplementation with antioxidants does not affect IC50, in contrast to other heavy metal-based agents. With respect to regulation, the Cdc25A nuclear localization signal (NLS) was identified and characterized. Data suggest that phosphorylation of S292, adjacent to the NLS, may promote nuclear localization. In the unperturbed cell cycle, S292 phosphorylation, a Chk1/2 target, a; | 2005 | 2018-06-15T10:53:58Z |
| [CDK 016] Flappiest Bits | Awww hells yeah! Jellica, the UK’s answer to goto80 (and IMO, the most underrated chiptuner in the country) kindly gives CDKr his ‘Flappiest Bits’ – an album which is similar to a wedding. How come? As there’s something old, something new, something borrowed, and something blue! (Some old tracks, some new tracks, a few covers and Pull My Nipples Hard , fact fans) Anyway, away with the awful analogies, just kick back and enjoy some fantastic chiptunes ‘n’ VST tracks! And if you like it, purchase his forthcoming miniCD from RetinaScan! The artwork for this is from the supremely talented Raquel Meyers , who also did the fantastic video for Jellica’s “I wld di 4 u” cover . Jellica also runs the UK’s second best chiptune weblabel (after CDKr of course ^_^), Kittenrock ! It’s down at the moment, and more’s the pity. Kittenrock and CDKr are also releasing a split CD-R soon, hopefully before the year is out! | 2008 | 2019-12-06T23:30:08Z |
| [CDK 056] Steady C - He Started It | [CDK 056] Steady C - He Started It | 2011 | 2020-01-05T21:08:08Z |
| [CDK 059] Cerebral Scars - Northern Dancing Town | [CDK 059] Cerebral Scars - Northern Dancing Town | 2012 | 2020-01-05T21:30:32Z |
| DTIC ADA415783: Regulated Transformation of Mammary Epithelial Cells by Transforming Growth Factor Beta 1 | We report that MMTV-DNIIR female mice have accelerated mammary gland differentiation during early pregnancy with impaired development during late pregnancy and lactation followed by delayed post-lactational involution. Mammary tumors, mostly carcinoma in situ, developed spontaneously in the MMTV-DNIIR mice with a long median latency (27.5 months). Invading carcinoma cells in MMTV-DNIIR animals showed loss of DNIIR transgene expression as determined by in situ hybridization. The data indicate that signaling from endogenous TGF-Betas not only plays an important role in normal mammary gland physiology but also can also suppress the early stage of tumor formation and contribute to tumor invasion once carcinomas have developed. The ability of the TGF-beta signaling pathways to inhibit proliferation of many epithelial cells while stimulating proliferation fibroblasts remains a conundrum. We found that the absence of RhoA and p160(ROCK) activity in fibroblastic NIH3T3 cells and its presence i; | 2003 | 2018-05-13T18:21:14Z |
| Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks. | This article is from BMC Systems Biology , volume 6 . Abstract Background: High-throughput measurement technologies produce data sets that have the potential to elucidate the biological impact of disease, drug treatment, and environmental agents on humans. The scientific community faces an ongoing challenge in the analysis of these rich data sources to more accurately characterize biological processes that have been perturbed at the mechanistic level. Here, a new approach is built on previous methodologies in which high-throughput data was interpreted using prior biological knowledge of cause and effect relationships. These relationships are structured into network models that describe specific biological processes, such as inflammatory signaling or cell cycle progression. This enables quantitative assessment of network perturbation in response to a given stimulus. Results: Four complementary methods were devised to quantify treatment-induced activity changes in processes described by ; | 2012 | 2014-10-25T01:34:45Z |
| DTIC ADA482640: Suppression of Prostate Tumors by INK4C and PTEN | Work during this entire funding period thoroughly characterized mutant mice in the cyclin-dependent kinase (CDK) inhibitor p18Ink4c, which causes hyperplastic cell growth in various tissues including the prostate and the lipid phosphatase Pten, which regulates cell growth and is highly associated with the development of human prostate cancer. The first two years of funding were highly productive and resulted in one manuscript publication supporting a functional collaboration between p18Ink4c and Pten in tumor suppression. Both the rate and spectrum of tumor development in the compound mutant mice were substantially accelerated and expanded. Combined genetic, histological, cellular, and biochemical analyses led to four major findings: (i) that p18 and PTEN each have previously unrecognized functions in tumor suppression, such as p18's function in the prostate and anterior lobe of the pituitary and PTEN's function in the pituitary, (ii) that the p18-Pten double mutant mice developed vari; | 2007 | 2018-06-22T04:53:07Z |