| Author | Title | Print-Published | Type | DOI@Sci-hub |
| CDK | | reference-entry | 10.1007/springerreference_92996 |
| Functions of CDK/cyclin Complexes in Endoreplication Regulation by the CDK Inhibitor SIAMESE | | dissertation | 10.31390/gradschool_dissertations.5173 |
| CDK | | reference-entry | 10.1007/springerreference_37256 |
| Pandit, J. | Novel CDK-5 inhibitors - crystal structure of inhibitor EFQ with CDK-2 | 2009/9/8 | dataset | 10.2210/pdb3igg/pdb |
| Pandit, J. | Novel CDK-5 inhibitors - crystal structure of inhibitor EFP with CDK-2 | 2009/9/8 | dataset | 10.2210/pdb3ig7/pdb |
| Figure 4—figure supplement 1. CDK–phosphorylation of ORC intrinsically inhibits helicase loading. | | component | 10.7554/elife.33309.013 |
| CDK Inhibitor R547 | | reference-entry | 10.32388/iap5sl |
| Willighagen, Egon | 10000 CDK commits! | | posted-content | 10.59350/w1hpp-ks316 |
| Willighagen, Egon | CDK Literature #3 | | posted-content | 10.59350/rkkty-a3w29 |
| Willighagen, Egon | CDK News | | posted-content | 10.59350/xf9bq-44218 |
| Cermin Dunia Kedokteran | | journal | 10.55175/cdk |
| CDK | | book-chapter | 10.1007/3-540-30683-8_274 |
| Willighagen, Egon | CDK Literature #4 | | posted-content | 10.59350/es4e7-esh15 |
| Willighagen, Egon | CDK Literature #1 | | posted-content | 10.59350/g22fv-gtc07 |
| CDK Inhibitor AT7519 | | reference-entry | 10.32388/286jz0 |
| CDK Gene Mutation | | reference-entry | 10.32388/kf9klo |
| Willighagen, Egon | StatCVS on CDK | | posted-content | 10.59350/q7ehm-v1m81 |
| Hu, X. | Cdc2: a monopotent or pluripotent CDK? | 2011/6 | journal-article | 10.1111/j.1365-2184.2011.00753.x |
| Willighagen, Egon | CDK Literature #2 | | posted-content | 10.59350/17nhx-htt54 |
| Supplementary file 1. CDK sequences used for phylogenetic analysis | | component | 10.7554/elife.10767.021 |
| Huang, Linda | Faculty Opinions recommendation of Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. | 2007/4/23 | dataset | 10.3410/f.1080804.533727 |
| CDK | | book-chapter | 10.1007/978-3-540-47648-1_959 |
| Willighagen, Egon | Nightly CDK builds now available | | posted-content | 10.59350/s63wt-hbx56 |
| Apodaca, Richard L. | Updating Ruby CDK | | posted-content | 10.59350/yy9a2-wy148 |
| Willighagen, Egon | CDK-Taverna fully recognized | | posted-content | 10.59350/pk40z-7z702 |
| cdk | | book-chapter | 10.1007/3-540-29832-0_321 |
| CDK | | book-chapter | 10.1007/978-3-540-38918-7_5357 |
| Willighagen, Egon | CDK Module dependencies #2 | | posted-content | 10.59350/e7qrk-ypg78 |
| CDK Inhibitor SNS-032 | | reference-entry | 10.32388/2sggcz |
| Schreiner, S. | Kongenitale Kniegelenkluxation (CDK) | 2012/1 | journal-article | 10.1007/s00132-011-1874-7 |
| Willighagen, Egon | The CDK data model #1 | | posted-content | 10.59350/4xfms-7nn46 |
| Carnero, A. | The INK4 Family of CDK Inhibitors | 1998 | book-chapter | 10.1007/978-3-642-71941-7_3 |
| cdk | | book-chapter | 10.1007/3-540-29719-0_321 |
| Willighagen, Egon | CDK Workshop - Day #2 | | posted-content | 10.59350/f7vn0-kqz26 |
| CDK Inhibitors | | book-chapter | 10.1007/978-3-540-47648-1_963 |
| Valk, Ervin | CDK signaling via nonconventional CDK phosphorylation sites | 2023/11/1 | journal-article | 10.1091/mbc.e22-06-0196 |
| | | journal-issue | 10.55175/cdk.v48i6 |
| Hu, Shanhu | Targeting anaphase catastrophe through CDK inhibition in lung cancer | | dissertation | 10.1349/ddlp.1623 |
| Degradation by Design: New Cyclin K Degraders from Old CDK Inhibitors | | component | 10.1021/acschembio.3c00616.s002 |
| | | journal-issue | 10.55175/cdk.v47i7 |
| Apodaca, Richard L. | Ruby CDK for Newbies | | posted-content | 10.59350/50ebs-4zq55 |
| Willighagen, Egon | Atom typing in the CDK | | posted-content | 10.59350/wm7aq-eqz10 |
| Grigoroudis, Asterios I. | Preparation of CDK/Cyclin Inhibitor Complexes for Structural Determination | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_4 |
| CDK Inhibitors | 2011 | book-chapter | 10.1007/978-3-642-16483-5_963 |
| Apodaca, Richard L. | CDK, the Ruby Way | | posted-content | 10.59350/49w1p-2y164 |
| Willighagen, Egon | Jumbo 5.0 and the CDK | | posted-content | 10.59350/y0mte-4ns18 |
| Willighagen, Egon | CDK close to entering Debian | | posted-content | 10.59350/dmspa-wyb25 |
| Willighagen, Egon | Single PDFs for CDK News articles | | posted-content | 10.59350/rgdzb-bfe36 |
| Willighagen, Egon | Calculating geometrical properties with the CDK | | posted-content | 10.59350/sy6r5-pzw09 |
| CDK Inhibitory Protein | | book-chapter | 10.1007/3-540-30683-8_276 |
| Alvira, Daniel | Drug Delivery Strategies of Chemical CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_12 |
| Willighagen, Egon | Java Server Pages with CDK functionality | | posted-content | 10.59350/3kvks-pdb73 |
| Gortat, Anna | Analysis of CDK Inhibitor Action on Mitochondria-Mediated Apoptosis | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_9 |
| | | journal-issue | 10.55175/cdk.v48i2 |
| CDK | 2011 | book-chapter | 10.1007/978-3-642-16483-5_959 |
| Willighagen, Egon | The CDK data classes and change notifications | | posted-content | 10.59350/3xsm0-bt478 |
| | | journal-issue | 10.55175/cdk.v47i11 |
| CDK/JAK2/FLT3 Inhibitor TG02 Citrate | | reference-entry | 10.32388/xklmgh |
| Willighagen, Egon | CDK Workshop - Days #3 and #4 | | posted-content | 10.59350/kvq10-snm07 |
| CDK-Activating Kinase Assembly Factor MAT1 | | reference-entry | 10.32388/6s4tbs |
| Willighagen, Egon | CDK Bug Squash Party - Day 5 | | posted-content | 10.59350/paxbm-rac78 |
| CDK | 2016 | book-chapter | 10.1007/978-3-662-46875-3_100468 |
| | | journal-issue | 10.55175/cdk.v49i0 |
| Apodaca, Richard L. | Scripting CDK with JRuby | | posted-content | 10.59350/sxxfq-shj88 |
| Willighagen, Egon | CDK and the Java 6 beta | | posted-content | 10.59350/6az21-1dt76 |
| Hirai, Hiroshi | Evaluating Chemical CDK Inhibitors as Cell Death Inducers | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_14 |
| Willighagen, Egon | CDK Bug Squash Party - Day 2 | | posted-content | 10.59350/wzs4m-9ky43 |
| Willighagen, Egon | The CDK/Metabolomics/Chemometrics Unconference results | | posted-content | 10.59350/f2ajz-tmr63 |
| Apodaca, Richard L. | Porting MX - CDK-Compatible VF Implementation | | posted-content | 10.59350/xat1r-hcs92 |
| | | journal-issue | 10.55175/cdk.v48i4 |
| Lacy, Susan | Identification of a p130 domain mediating interactions with cyclin A/cdk 2 and cyclin E/cdk 2 complexes | 1997/5/22 | journal-article | 10.1038/sj.onc.1201085 |
| | | journal-issue | 10.55175/cdk.v47i10 |
| Willighagen, Egon | CDK Bug Squash Party - Day 1 | | posted-content | 10.59350/y5srm-hzx87 |
| Willighagen, Egon | Jumbo 5.0 and CML support in CDK | | posted-content | 10.59350/dzvnw-3b413 |
| | | journal-issue | 10.55175/cdk.v47i12 |
| Apodaca, Richard L. | Scripting Molecular Fingerprints with Ruby CDK | | posted-content | 10.59350/xgf37-ggz21 |
| | | journal-issue | 10.55175/cdk.v47i9 |
| | | journal-issue | 10.55175/cdk.v48i5 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s003 |
| Guevara, Tatiana | Evaluating the Effects of CDK Inhibitors in Ischemia–Reperfusion Injury Models | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_10 |
| Willighagen, Egon | UML diagram of CDK module dependencies | | posted-content | 10.59350/a3r1n-72841 |
| Upton, Jason W. | Evidence for CDK-Dependent and CDK-Independent Functions of the Murine Gammaherpesvirus 68 v-Cyclin | 2006/12/15 | journal-article | 10.1128/jvi.01722-06 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s002 |
| | | journal-issue | 10.55175/cdk.v47i8 |
| | | grant | 10.55776/tai3266225 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 1999/8/1 | report | 10.21236/ada378108 |
| | | journal-issue | 10.55175/cdk.v48i1 |
| | | journal-issue | 10.55175/cdk.v48i3 |
| Ruiz, E. Josué | Meiotic Inactivation of Xenopus Myt1 by CDK/XRINGO, but Not CDK/Cyclin, via Site-Specific Phosphorylation | 2008/10 | journal-article | 10.1016/j.molcel.2008.08.029 |
| Lee, Young-Sam | Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates | 2007/4/6 | journal-article | 10.1126/science.1139080 |
| | | journal-issue | 10.55175/cdk.v42i10 |
| Guha, Rajarshi | rcdk: Interface to the 'CDK' Libraries | 2006/10/4 | dataset | 10.32614/cran.package.rcdk |
| GROTH, A | High-density growth arrest in Ras-transformed cells: low Cdk kinase activities in spite of absence of p27 Cdk-complexes | 2005/9 | journal-article | 10.1016/j.cellsig.2004.11.021 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 2000/9/1 | report | 10.21236/ada392485 |
| Apodaca, Richard L. | CDK, the Ruby Way: RCDK-0.2.0 | | posted-content | 10.59350/ev966-zz940 |
| Degradation by Design: New Cyclin K Degraders from Old CDK Inhibitors | | component | 10.1021/acschembio.3c00616.s001 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s001 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s004 |
| Gallastegui, Edurne | Immunoprecipitation of Cdk–Cyclin Complexes for Determination of Kinase Activity | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_1 |
| Apodaca, Richard L. | Drawing 2-D Structures with Structure-CDK | | posted-content | 10.59350/qxc8d-c1w35 |
| Cyclin-dependent Kinase (CDK) Inhibitor | | book-chapter | 10.1007/3-540-30683-8_390 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 1998/8/1 | report | 10.21236/ada359281 |
| Gangopadhyay, Aditi | The Prospects of CDK Targeting and Clinical Application of CDK Inhibitors in Cancer | 2018/12/5 | book-chapter | 10.2174/9781681087016118090008 |
| Willighagen, Egon | Test results for the CDK 1.0.x branch | | posted-content | 10.59350/ry980-qya21 |
| Willighagen, Egon | CDK 1.0: a milestone after 7 year of development | | posted-content | 10.59350/qd21w-71g30 |
| lavarone, Antonio | Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15 | 1997/5 | journal-article | 10.1038/387417a0 |
| Fisher, Robert P | Faculty Opinions recommendation of Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation. | 2008/11/11 | dataset | 10.3410/f.1125916.583024 |
| Willighagen, Egon | The molecular QSAR descriptors in the CDK | | posted-content | 10.59350/47rre-wwc20 |
| Chiarelli, C | Cyclin D, CDK and CDK Inhibitors in Melanocytic Neoplasms. | 1997/8 | journal-article | 10.1097/00000372-199708000-00072 |
| Pérez-Benavente, Beatriz | Cell Synchronization Techniques to Study the Action of CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_8 |
| Willighagen, Egon | CDK Debug classes and fixing the ModelBuilder3D bug | | posted-content | 10.59350/6p49t-sj396 |
| Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk) | | component | 10.1021/acschembio.7b00972.s002 |
| Willighagen, Egon | CDK News 2.3 and InChI's | | posted-content | 10.59350/z97vw-87009 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v49i2.1746 |
| Synthesis of benzofuropyridine derivatives as CDK-5 inhibitors and anticancer agents | | dissertation | 10.58837/chula.the.2022.1218 |
| CDK | | other | 10.1002/0471684228.egp01945 |
| Guha, Rajarshi | rcdklibs: The CDK Libraries Packaged for R | 2009/1/8 | dataset | 10.32614/cran.package.rcdklibs |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v48i12.1586 |
| Willighagen, Egon | CDK Bug Squash Party - Day 3 and 4 | | posted-content | 10.59350/zwkym-aty79 |
| Willighagen, Egon | InChI's in LaTex and CDK News | | posted-content | 10.59350/hysd0-wvc09 |
| | | grant | 10.55776/t393 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v48i12.1589 |
| Palomino-Schätzlein, Martina | Metabolomic Applications to the Characterization of the Mode-of-Action of CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_16 |
| Multiplexed Profiling of CDK Kinase Activities in Tumor Biopsies with Fluorescent Peptide Biosensors | | component | 10.1021/acssensors.4c00139.s001 |
| Figure 3: The efficiency of tumor markers in distinguish CDK patients from healthy control. | | component | 10.7717/peerj.19240/fig-3 |
| CDK | 2008 | book-chapter | 10.1007/978-1-4020-6754-9_2580 |
| Willighagen, Egon | R/CDK install fails on GCC 4.0 systems | | posted-content | 10.59350/b1vyj-0kd63 |
| Willighagen, Egon | CDK is now available from your nearest Debian mirror | | posted-content | 10.59350/g5s78-zqk90 |
| Futcher, A. B. | General Methods for Identifying G1-phase Substrates of Cdk Protein Kinases | 1999/6/1 | report | 10.21236/ada374137 |
| Guidato, Sonia | Cyclin D2 Interacts with cdk‐5 and Modulates Cellular cdk‐5/p35 Activity | 1998/1 | journal-article | 10.1046/j.1471-4159.1998.70010335.x |
| -, - | Indeks Akhir Tahun | | journal-article | 10.55175/cdk.v48i12.1588 |
| | | grant | 10.35802/065956 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v49i1.1648 |
| Many Hats for Cdk Inhibitor | 2006/1/10 | journal-article | 10.1126/stke.3172006tw468 |
| Tsutsui, Taiki | Identification of target genes for the CDK subunits of the Mediator complex | 2011/12 | journal-article | 10.1111/j.1365-2443.2011.01565.x |
| CDK Inhibitors, Endocrine Therapy for Male Patients With Breast Cancer | 2019/3/8 | dataset | 10.1200/adn.19.190134 |
| Dutto, Ilaria | Assessing Cell Cycle Independent Function of the CDK Inhibitor p21CDKN1A in DNA Repair | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_11 |
| Apodaca, Richard L. | Source Code Documentation in Ruby: RDoc for Ruby CDK | | posted-content | 10.59350/jf1hb-6ev38 |
| CELL CYCLE-REGULATION OF THE FANCD2 PROTEIN VIA CDK-MEDIATED S592 PHOSPHORYLATION | | dissertation | 10.23860/thesis-cantres-velez-juan-2020 |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v49i2.1745 |
| Willighagen, Egon | Janocchio: Jmol and CDK based 1H coupling constant prediction | | posted-content | 10.59350/rxzh8-9yr48 |
| Figure 7. Model of how meiotic cells inhibit DNA replication during the MI–MII transition. | | component | 10.7554/elife.33309.026 |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v49i1.1647 |
| Willighagen, Egon | Protein support in Bioclipse using Jmol and the CDK | | posted-content | 10.59350/23wn4-1nt07 |
| Willighagen, Egon | Modern chemistry in the CDK: beyond the two-atom bond | | posted-content | 10.59350/h2ytc-6pt51 |
| Willighagen, Egon | Comparing JUnit test results between CDK trunk/ and a branch | | posted-content | 10.59350/zs3tv-pp865 |
| Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk) | | component | 10.1021/acschembio.7b00972.s001 |
| Lone, Waseem | Silicon-tethered colchicine aryne cyclo-adduct as a potent molecule for the abrogation of epithelial to mesenchymal transition via modulating cell cycle regulatory CDK-2 and CDK-4 kinases | | posted-content | 10.26434/chemrxiv-2024-rs3lh |
| Nishizawa, Masafumi | Mouse Cyclin-dependent Kinase (Cdk) 5 Is a Functional Homologue of a Yeast Cdk, Pho85 Kinase | 1999/11 | journal-article | 10.1074/jbc.274.48.33859 |
| Apodaca, Richard L. | From IUPAC Name to Molecular Formula with Ruby CDK | | posted-content | 10.59350/1nn38-3ef94 |
| Zettelmeyer, Florian | CDK Digital Marketing: Addressing Channel Conflict with Data Analytics | 2014 | reference-book | 10.4135/9781473969650 |
| Willighagen, Egon | Open Source Java tool chain: CDK compiles and JUnit tests run | | posted-content | 10.59350/933ah-c7f36 |
| Willighagen, Egon | Trouble running the CDK JUnit tests with Cacao and Kaffe | | posted-content | 10.59350/rn78z-r7j37 |
| Shimotohno, Akie | CDKPhosphorylation | | other | 10.1002/9781119312994.apr0336 |
| Apodaca, Richard L. | MX Performance Comparison #3: Substructure Search in MX and CDK | | posted-content | 10.59350/n4y52-t3a30 |
| Futcher, A. B. | General Methods for Identifying Gl-phase Substrates of Cdk Protein Kinases. | 1998/6/1 | report | 10.21236/ada366953 |
| Prasetya, Damar | Varisela Neonatal | | journal-article | 10.55175/cdk.v47i12.1239 |
| Cyclin-Dependent Kinase (CDK) Inhibitors: StructureActivity Relationships and Insights into the CDK2 Selectivity of 6Substituted 2Arylaminopurines | | component | 10.1021/acs.jmedchem.6b01254.s002 |
| Apodaca, Richard L. | From SMILES to InChI: Rino, CDK, and Ruby Java Bridge | | posted-content | 10.59350/hra9n-qry69 |
| Purnamasari, Maretta Rosabella | Iktiosis Vulgaris | | journal-article | 10.55175/cdk.v47i10.1085 |
| Apodaca, Richard L. | Agile Chemical Informatics Development with CDK and Ruby: RCDK-0.3.0 | | posted-content | 10.59350/c8h7w-n4922 |
| Protein kinase (CDK/MAK) | | book-chapter | 10.1007/978-3-540-49756-1_63 |
| Pohl, M. | GWK/CDK-Bank | 1994/1/1 | book-chapter | 10.4337/9781781954218.00152 |
| Cyclin-Dependent Kinase (CDK) Inhibitors: StructureActivity Relationships and Insights into the CDK2 Selectivity of 6Substituted 2Arylaminopurines | | component | 10.1021/acs.jmedchem.6b01254.s001 |
| EMPIAR dataset | | | 10.6019/empiar-10438 |
| Shimotohno, Akie | CDK Phosphorylation | | book-chapter | 10.1002/9780470988923.ch5 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/8/16 | peer-review | 10.1111/odi.13687/v1/review1 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/8/17 | peer-review | 10.1111/odi.13687/v1/review2 |
| Roovers, Kristin | Role of Cyclin D1 and cdk Inhibitors in Breast Cancer Pathogenesis | 2002/5/1 | report | 10.21236/ada407447 |
| Apodaca, Richard L. | MX Performance Comparison #2: Exhaustive Ring Perception in MX and CDK | | posted-content | 10.59350/tv70e-5c238 |
| Dutta, Anindya | Action of the p53 Effector, p2l, on its Targets: Cyclin cdk and PCNA | 1998/10/1 | report | 10.21236/ada368460 |
| Apodaca, Richard L. | Easily Calculate TPSA Descriptors from SMILES Strings Using Ruby CDK | | posted-content | 10.59350/8xxp3-b8077 |
| Kawauchi, Takeshi | Extra‐cell cycle regulatory functions of cyclin‐dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders | 2013/3 | journal-article | 10.1111/gtc.12029 |
| Rusli, Richardo | Retinitis Pigmentosa | | journal-article | 10.55175/cdk.v47i7.597 |
| Durandau, Eric | Cross-regulation between CDK and MAPK control cellular fate | | posted-content | 10.1101/274787 |
| Ringer, Lymor | Role of p53 in cdk Inhibitor VMY-1-103-induced Apoptosis in Prostate Cancer | 2013/11/1 | report | 10.21236/ada592440 |
| Anurogo, Dito | Cancer Stem Cells | | journal-article | 10.55175/cdk.v48i11.1549 |
| Mahendra, Cipta | Peutz-Jeghers Syndrome | | journal-article | 10.55175/cdk.v48i12.1574 |
| Yu, Bo | Downregulation of Cyclin D1 Alters cdk 4- and cdk 2-Specific Phosphorylation of Retinoblastoma Protein | 2000/6 | journal-article | 10.1006/mcbr.2000.0238 |
| Cheng, Weiyan | Recent development of CDK inhibitors: An overview of CDK/inhibitor co-crystal structures | 2019/2 | journal-article | 10.1016/j.ejmech.2019.01.003 |
| ., Sukamto | Penanganan Ketoasidosis Diabetik pada Anak | | journal-article | 10.55175/cdk.v49i9.2039 |
| Wysocki, Robert | CDK Pho85 targets CDK inhibitor Sic1 to relieve yeast G1 checkpoint arrest after DNA damage | 2006/10 | journal-article | 10.1038/nsmb1139 |
| Ringer, Lymor | Role of p53 in cdk Inhibitor VMY-1-103-Induced Apoptosis in Prostate Cancer | 2012/9/1 | report | 10.21236/ada567635 |
| Apodaca, Richard L. | Open Benchmarks for Cheminformatics: First Performance Comparison Between CDK and MX | | posted-content | 10.59350/7nc6k-w4216 |
| Cyclin‐Dependent Protein Kinase (
CDK
) | | other | 10.1002/0471684228.egp02997 |
| Srivastava, Mansi | Lineage-specific CDK activity dynamics characterize early mammalian development | | posted-content | 10.1242/prelights.38013 |
| Nishizawa, Masafumi | Phosphorylation of Sic1, a Cyclin-dependent Kinase (Cdk) Inhibitor, by Cdk Including Pho85 Kinase Is Required for Its Prompt Degradation | 1998/9 | journal-article | 10.1091/mbc.9.9.2393 |
| CDK | 2006 | book-chapter | 10.1007/3-540-29623-9_10003 |
| Katz, Max | RichFaces CDK: Building Custom Components | 2011 | book-chapter | 10.1007/978-1-4302-3450-0_14 |
| Sanchez-Diaz, Alberto | The Mitotic Exit Network and Cdc14 phosphatase initiate cytokinesis by counteracting CDK phosphorylations and blocking polarised growth | 2012/8/29 | journal-article | 10.1038/emboj.2012.224 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/10/7 | peer-review | 10.1111/odi.13687/v2/review1 |
| Apodaca, Richard L. | Cheminformatics for the Web: Convert SD Files to HTML with Ruby CDK | | posted-content | 10.59350/gvwgq-b0x50 |
| Cyclin dependent kinase (CDK) | 2010/11 | journal-article | 10.1038/scibx.2010.1319 |
| Cyclin-Dependent Protein Kinases (CDK) | 2008 | book-chapter | 10.1007/978-1-4020-6754-9_3981 |
| Pérez-Hidalgo, Livia | CDK Inhibitors | 2013 | book-chapter | 10.1007/978-1-4419-9863-7_12 |
| Apodaca, Richard L. | From InChI to Image with Ruby Open Babel and Ruby CDK | | posted-content | 10.59350/r891p-vmx14 |
| Lawrenti, Hastarita | Hemofilia dan Perkembangan Terapinya | | journal-article | 10.55175/cdk.v48i9.1496 |
| Figure 4: The efficiency of tumor markers in distinguish CDK patients with normal serum creatinine from healthy controls. | | component | 10.7717/peerj.19240/fig-4 |
| Chandra, Rudi | Tatalaksana Melanoma Maligna Kutaneus | | journal-article | 10.55175/cdk.v48i7.1453 |
| Fig. 1. Ovarian enlargement and lack of blood flow in the CDK regimen with a full bladder | | component | 10.17816/psaic575-154 |
| Yuliana, Jeni | Aspek Klinis Ambliopia | | journal-article | 10.55175/cdk.v49i1.1639 |
| Ogata, Ryohei | Resistance to cyclin-dependent kinase (CDK) 4/6 inhibitors confers cross-resistance to other CDK inhibitors but not to chemotherapeutic agents in breast cancer cells | 2021/1 | journal-article | 10.1007/s12282-020-01150-8 |
| Turner, N. | Targeting the CDK 4-6 pathway | 2019/3 | journal-article | 10.1016/s0960-9776(19)30078-5 |
| Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor | | component | 10.1021/acs.oprd.1c00255.s001 |
| Lawrensia, Sherly | Diagnosis dan Tatalaksana Artritis Tuberkulosis | | journal-article | 10.55175/cdk.v47i8.773 |
| Teo, Gloria | Diagnosis dan Tatalaksana Kegawatdaruratan Hiperkalemia | | journal-article | 10.55175/cdk.v48i8.1447 |
| Aprelikova, Olga | Both p16 and p21 Families of Cyclin-dependent Kinase (CDK) Inhibitors Block the Phosphorylation of Cyclin-dependent Kinases by the CDK-activating Kinase | 1995/8 | journal-article | 10.1074/jbc.270.31.18195 |
| Lawrensia, Sherly | Lung Abscess: Diagnosis and Treatment | | journal-article | 10.55175/cdk.v48i5.1373 |
| When a CDK Is Really a Transcription Factor | 2005/1/11 | journal-article | 10.1126/stke.2662005tw14 |
| Prasetio, Adrian | Gangguan Psikiatri Terkait Kafein | | journal-article | 10.55175/cdk.v47i7.603 |
| | | grant | 10.55776/p19894 |
| Febriana, Lydia | Suplemen untuk Terapi Obesitas | | journal-article | 10.55175/cdk.v49i0.1964 |
| Meijer, Laurent | CDK Inhibitors | 2002 | book-chapter | 10.1016/b978-012476249-7/50008-4 |
| p27
Kip1−/−
Strain 3 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg10 |
| Lone, Waseem Iqbal | Discovery of Colchicine Aryne Cyclo-Adduct as a Potent Molecule for the Abrogation of Epithelial to Mesenchymal Transition Via Modulating Cell Cycle Regulatory Cdk-2 and Cdk-4 Kinases | | posted-content | 10.2139/ssrn.4814175 |
| Cyclin dependent kinase (CDK) | 2012/4 | journal-article | 10.1038/scibx.2012.385 |
| Cyclin dependent kinase (CDK) | 2010/3 | journal-article | 10.1038/scibx.2010.272 |
| Futcher, A. B. | General Methods for Identifying G1-Phase Substrates of Cdk Protein Kinases. | 1996/6/1 | report | 10.21236/ada323678 |
| RAYNAL, S | DIFFERENTIAL-EFFECTS OF TRANSFORMING GROWTH-FACTOR-BETA-1 ON PROTEIN-LEVELS OF P21 WAF AND CDK-2 AND ON CDK-2 KINASE-ACTIVITY IN HUMAN RD AND CCL64 MINK LUNG-CELLS | | journal-article | 10.3892/ijo.7.2.337 |
| Nitiyoso, Nugroho | Aspek Imunitas pada COVID-19 | | journal-article | 10.55175/cdk.v48i9.1497 |
| ., Suharto | Fisioterapi Kasus Cerebral Palsy Kuadriplegia Spastik | | journal-article | 10.55175/cdk.v49i9.2036 |
| Fauzi, Ahmad | Haglund Deformity: Diagnosis and Treatment | | journal-article | 10.55175/cdk.v49i10.2067 |
| Yahya, Willy | Retinopati Prematuritas : Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v47i10.1080 |
| EMPIAR dataset | | | 10.6019/empiar-10561 |
| Dai, Yun | CDK Inhibitors in Multiple Myeloma | 2008 | book-chapter | 10.1007/978-1-59745-564-0_22 |
| Larochelle, Stéphane | CDK-Activating Kinases: Detection and Activity Measurements | | book-chapter | 10.1385/1-59259-857-9:279 |
| Lukito, Johan Indra | Tinjauan atas Terapi Insulin | | journal-article | 10.55175/cdk.v47i9.917 |
| Karyadi, Erlinda | Cutaneous Mucormycosis | | journal-article | 10.55175/cdk.v49i2.1726 |
| Henri, P. | Psoriatic epidermis is associated with upregulation of
CDK
2 and inhibition of
CDK
4 activity | 2020/3 | journal-article | 10.1111/bjd.18178 |
| Karyadi, Erlinda | Cutaneous Mucormycosis | | journal-article | 10.55175/cdk.v49i2.1740 |
| Dai, Yun | CDK Inhibitors in Leukemia and Lymphoma | 2019/9/17 | book-chapter | 10.1201/9780429114670-15 |
| Nitiyoso, Nugroho | Pilihan Pengobatan Sistemik pada Psoriasis | | journal-article | 10.55175/cdk.v49i3.1775 |
| Putri, Zanty Rakhmania | Bell’s Palsy: Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v49i8.1986 |
| Pricelda, Alicia | Tren Terapi Age-Related Macular Degeneration | | journal-article | 10.55175/cdk.v48i12.1584 |
| Bisbis, Badia | Cyclin-dependent Kinase (CDK) Inhibitors Regulate the CDK-Cyclin Complex Activities in Endoreduplicating Cells of Developing Tomato Fruit | 2006/3 | journal-article | 10.1074/jbc.m506587200 |
| -, Tommy | Angina Prinzmetal - Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v48i6.1431 |
| Afifah Nurullah, Fitri | Tinjauan atas N-Nitrosodimethylamine (NDMA) | | journal-article | 10.55175/cdk.v47i12.1249 |
| -, Carlson | Tatalaksana Demam pada Anak | | journal-article | 10.55175/cdk.v47i11.1200 |
| p27
Kip1−/−
Strain 2 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg9 |
| Chandra, Rudi | Pilihan Pengobatan Dermatologis Penuaan Periorbital | | journal-article | 10.55175/cdk.v47i12.1241 |
| Morgan, David O. | Principles of CDK regulation | 1995/3 | journal-article | 10.1038/374131a0 |
| Cicenas, Jonas | CDK Inhibitors and FDA: Approved and Orphan | | journal-article | 10.3390/cancers16081555 |
| Müllers, Erik | Cdk activity drives senescence from G2 phase | | posted-content | 10.1101/041723 |
| Kusumo, Inosensia Diajeng | Tinjauan Atas Pioderma | | journal-article | 10.55175/cdk.v49i4.1822 |
| CDK Inhibitor Triples PFS in Breast Cancer | 2013/1/1 | journal-article | 10.1158/2159-8290.cd-nb2012-149 |
| ASCO TAPUR, CDK Studies Endeavor to Fill Gaps in Personalized Cancer Care Research | 2024/12/1 | dataset | 10.1200/acon.24.00037 |
| Fanardy, Angeline | Toksin Botulinum untuk Kasus Urogenital | | journal-article | 10.55175/cdk.v48i3.1337 |
| Dinari, Nur Alfi | Miopia: Etiologi dan Terapi | | journal-article | 10.55175/cdk.v49i10.2069 |
| Ciatawi, Kartini | Patofisiologi Spinal Cord Injury | | journal-article | 10.55175/cdk.v49i5.1848 |
| Ciatawi, Kartini | Patofisiologi Spinal Cord Injury | | journal-article | 10.55175/cdk.v49i9.2032 |
| EMPIAR dataset | | | 10.6019/empiar-10431 |
| Johan, Michael | Evaluasi dan Tatalaksana Hipernatremia | | journal-article | 10.55175/cdk.v48i6.1441 |
| Palacios Blanco, Inés | CDK phospho-regulation of the Rad51-accessory factor Sfr1 and its role in meiotic recombination | | dissertation | 10.14201/gredos.161088 |
| Renita Sanyasi, Rosa De Lima | Sindrom Mona Lisa | | journal-article | 10.55175/cdk.v48i1.1258 |
| Mahendro, Della Sulamita | Penggunaan Antivirus untuk COVID-19 | | journal-article | 10.55175/cdk.v48i7.1459 |
| Kristiningrum, Esther | Penggunaan Hydroxychloroquine dalam Tatalaksana Covid-19 | | journal-article | 10.55175/cdk.v47i12.1246 |
| Suryani, Adelia | Faktor-Faktor yang Memengaruhi Pigmentasi Manusia | | journal-article | 10.55175/cdk.v47i11.1195 |
| Permasutha, Made Bayu | Tinjauan atas Kanker Rongga Mulut | | journal-article | 10.55175/cdk.v48i3.1327 |
| Feinberg, Bruce A. | Prescribing preferences for hormone sensitive (HR+) metastatic breast cancer (mBC) in the CDK 4/6 inhibitor (CDK 4/6i) era. | 2020/5/20 | journal-article | 10.1200/jco.2020.38.15_suppl.e13058 |
| Setiawan, Michael | Mielopati Non Kompresif: Pendekatan Diagnosis | | journal-article | 10.55175/cdk.v47i9.909 |
| Dewi, Nadia Puspa | Aspek Klinis Dermatitis Seboroik | | journal-article | 10.55175/cdk.v49i6.1881 |
| p27
Kip1−/−
Strain 1 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg8 |
| Carrieri, Francesca Anna | CDK
1 and
CDK
2 regulate
NICD
1 turnover and the periodicity of the segmentation clock | 2019/7 | journal-article | 10.15252/embr.201846436 |
| Decision letter: CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading | 2016/12/19 | peer-review | 10.7554/elife.23352.021 |
| Apodaca, Richard L. | CampDepict: Building a Simple SMILES Depict Web Application With JRuby, Structure CDK, and Camping | | posted-content | 10.59350/d2m6v-tag27 |
| Ratna Sari, Ihda Zuyina | Gambaran Sistiserkosis dan Taeniasis | | journal-article | 10.55175/cdk.v49i3.1768 |
| Stanley, Jone A. | Chromium-VI arrests cell cycle and decreases granulosa cell proliferation by down-regulating cyclin-dependent kinases (CDK) and cyclins and up-regulating CDK-inhibitors | 2011/7 | journal-article | 10.1016/j.reprotox.2011.05.007 |
| Mahendra, Cipta | Terapi Berbasis Sel: Perkembangan Terkini | | journal-article | 10.55175/cdk.v49i3.1769 |
| Clinical Trial in Healthy Volunteers and Subjects With CDK | | journal-article | 10.31525/ct1-nct03893799 |
| Cyclin dependent kinase (CDK); p53 | 2012/10 | journal-article | 10.1038/scibx.2012.1028 |
| Wijaya, Sandy | Diagnosis dan Tatalaksana Polisitemia Vera | | journal-article | 10.55175/cdk.v47i7.596 |
| Lawrenti, Hastarita | Penghambat Immune Checkpoint untuk Terapi Kanker | | journal-article | 10.55175/cdk.v49i0.1966 |
| Shamsi, Zahra | Concestor kinase activation mechanism uncovers the cyclin dependence of CDK family kinases | | posted-content | 10.1101/410902 |
| Lukito, Johan Indra | Gunakan Insulin dengan CERMAT | | journal-article | 10.55175/cdk.v47i10.1093 |
| Cherub, Jane | Terapi Antikoagulan pada COVID-19 | | journal-article | 10.55175/cdk.v48i6.1436 |
| 4-Arylazo-3, 5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects | | component | 10.1021/jm0605740.s001 |
| CRESCENZI, ELVIRA | Association of Bcl‐2 with Cyclin A/Cdk‐2 Complex and Its Effects on Cdk‐2 Activity | 2002/11 | journal-article | 10.1111/j.1749-6632.2002.tb04647.x |
| Tan, Christine | Trombosis pada Pasien COVID-19 | | journal-article | 10.55175/cdk.v48i12.1571 |
| Besser, Alexandra | CDK Inhibitors in Normal and Malignant Cells | 2023 | book-chapter | 10.1016/b978-0-12-821618-7.00221-2 |
| Mahendrakrisna, Daniel | Tatalaksana Epilepsi Refrakter | | journal-article | 10.55175/cdk.v47i9.911 |
| Decision letter: CDK control pathways integrate cell size and ploidy information to control cell division | 2020/12/20 | peer-review | 10.7554/elife.64592.sa1 |
| Wijaya, Lupita | Tatalaksana Nyeri Neuropatik Perifer dengan Sediaan Patch | | journal-article | 10.55175/cdk.v48i9.1484 |
| Falco, Giulia De | Cdk Inhibitors: Background and Introduction | | book-chapter | 10.1385/1-59259-401-8:01 |
| Chandra, Rudi | Aspek Dermatologi Penuaan Kulit Periorbital | | journal-article | 10.55175/cdk.v47i9.920 |
| -, Cecile | Diagnosis dan Tatalaksana Paroxysmal Nocturnal Hemoglobinuria | | journal-article | 10.55175/cdk.v48i7.1452 |
| Kumala, Marcia | Suplementasi Vitamin B1 untuk Pasien Sepsis | | journal-article | 10.55175/cdk.v47i8.783 |
| Decker, T | Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27 | 2002/3/1 | journal-article | 10.1038/sj.leu.2402389 |
| Mostafa, Heba H. | Herpes Simplex Virus 1 Upregulates p35, Alters CDK-5 Localization, and Stimulates CDK-5 Kinase Activity during Acute Infection in Neurons | 2015/5 | journal-article | 10.1128/jvi.00106-15 |
| Sondhi, Sham M. | Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases | 2006/6 | journal-article | 10.1016/j.bmc.2006.01.054 |
| First CDK 4/6 Inhibitor Heads to Market | 2015/4/1 | journal-article | 10.1158/2159-8290.cd-nb2015-028 |
| Dianky, Amanda | Peran Nutrigenomik pada Tata Laksana Obesitas | | journal-article | 10.55175/cdk.v49i0.1965 |
| Irsyada Yusuf, Amry | Diagnosis dan Tatalaksana Kriptorkhismus | | journal-article | 10.55175/cdk.v48i3.1330 |
| Wijaya, Meiliyana | Meningitis Kriptokokus pada Penderita HIV | | journal-article | 10.55175/cdk.v48i1.1256 |
| Erdiana, Grace | Anensefali Diduga Akibat Defisiensi Asam Folat | | journal-article | 10.55175/cdk.v48i7.1455 |
| Peer Review #1 of Rising Cdk/Cyclin levels promote, and then suppress, centrosome growth to help set centrosome size | 2023/9/5 | peer-review | 10.15252/rc.2023005411 |
| Peer Review #2 of Rising Cdk/Cyclin levels promote, and then suppress, centrosome growth to help set centrosome size | 2023/9/5 | peer-review | 10.15252/rc.2023989464 |
| Patterson, James O. | Synergistic CDK control pathways maintain cell size homeostasis | | posted-content | 10.1101/2020.11.25.397943 |
| A novel and robust molecular switch actuating the quantitative model of eukaryotic Cdk control | | proceedings-article | 10.18699/sbb-2022-104 |
| Bird, R.Curtis | The Cyclin/Cyclin-Dependent Kinase (cdk) Complex | 1997 | book-chapter | 10.1016/b978-012100160-5/50006-3 |
| Mueller, Daniel | Abstract 2821: Characterization of CDK inhibitors in a biochemical assay using a comprehensive panel of human CDK-cyclin complexes | 2016/7/15 | journal-article | 10.1158/1538-7445.am2016-2821 |
| Title | Description | Published | Added |
| github.com-angular-components_-_2021-03-13_17-17-56 | Component infrastructure and Material Design components for Angular Official components for Angular The Angular team builds and maintains both common UI components and tools to help you build yourown custom components. The team maintains several npm packages. | Package | Description | Docs || ------------------------- | ----------------------------------------------------------------------------------- | ---------------- || @angular/cdk | Library that helps you author custom UI components with common interaction patterns | Docs || @angular/material | Material Design UI components for Angular applications | Docs || @angular/google-maps | Angular components built on top of the Google Maps JavaScript API | Docs || @angular/youtube-player | Angular component built on top of the YouTube Player API | Docs | Quick links Documentation, demos, and guides | Frequently Asked Questions | Community Google group | Contributing | StackBlitz Template Getting started See our Getting Started Guide if yo; | 2021 | 2021-03-13T21:27:21Z |
| EP 12: Kelsey Smith - Abducted In Broad Daylight | Kelsey Smith was just 18 years old when she was abducted from a Target parking lot in Overland Park, Kansas in June 2007. Finding her would take a battle with a cellular phone company and heartbreaking surveillance video from Target, that shows that no one is ever really safe, even if you're running a simple errand in broad daylight. A special thank you to Kelsey's mom, Missey Smith, for speaking with me for this episode. To learn more about the Kelsey Smith Foundation and the Kelsey Smith Act, please visit kelseysarmy.org. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode: - Summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/cdk/13112 - Like Music (cdk Mix) by c; | 2017 | 2023-07-08T12:40:23Z |
| Ep 10 Part 1: Kristine Bunch's Nightmare | In part 1 of this episode, you'll hear about one woman's nightmare come true. In 1995, 21-year-old Kristine Bunch was abruptly awoken in the early morning hours to discover that her house was on fire. After escaping the flames, she watched in horror as firefighters were unable to save her 3-year-old son who was still trapped inside. Within hours of being released from the hospital, she discovered that detectives had a theory about the fire - someone had started the fire on purpose, and their main suspect was Kristine. A special thank you to Kristine Bunch for helping me tell her story.Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie. Music featured in this episode: Like Music (cdk Mix) by cdk (c) copyright 2015 Licensed under a Creative Commons Attribution Share-Alike (3.0) license. htt; | 2016 | 2023-07-08T12:43:39Z |
| Faulkner v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-10-12T07:17:13Z |
| The arginine methyltransferase PRMT6 regulates cell proliferation and senescence through transcriptional repression of tumor suppressor genes. | This article is from Nucleic Acids Research , volume 40 . Abstract The protein arginine methyltransferase 6 (PRMT6) is a coregulator of gene expression and executes its repressing as well as activating function by asymmetric dimethylation of histone H3 at R2 (H3 R2me2a). Given that elevated expression levels of PRMT6 have been reported in various cancer types, we explore here its role in cell proliferation and senescence. We find that knockdown of PRMT6 results in proliferation defects of transformed as well as non-transformed cells, causes G1-phase arrest and induces senescence. This phenotype is accompanied by transcriptional upregulation of important cell cycle regulators, most prominently the cyclin-dependent kinase (CDK) inhibitor gene p21 (p21CIP1/WAF1, CDKN1A) and p16 (p16INK4A, CDKN2A). Chromatin immuno-precipitation analysis reveals that the p21 gene is a direct target of PRMT6 and the corresponding histone mark H3 R2me2a. Using a cell model of oncogene-induced senescence (OIS; | 2012 | 2014-10-28T05:36:50Z |
| So It Seemed (Autobiography of a newspaper editor & publisher) | | 1952 | 2023-12-21T19:12:59Z |
| Docking studies for screening anticancer compounds of Azadirachta indica using Saccharomyces cerevisiae as model system. | This article is from Journal of Natural Science, Biology, and Medicine , volume 5 . Abstract Introduction:: Plants have a long history of use in the treatment of cancer. Plant-derived compounds have played an important role in the development of several clinically useful anticancer agents. In the recent years, more emphasis has been placed on identifying plant-derived compounds that can be used as an effective treatment for life-threatening diseases such as cancer. Cancer is a disease where there is abnormal cell proliferation. The proliferation of the cancer cells are restrained by cdk/cyclin complexes, which control the normal process of cell cycle. Materials and Method:: The current study involves the investigation of the anticancer property of the chemical compounds present in the leaves of Azadirachta indica by performing docking studies with the cell cycle control protein using Arguslab. Result:: The compounds were docked with the cdk1 protein to identify suitable inhibitors agai; | 2014 | 2014-10-24T01:23:37Z |
| Historic Preservation Awards 2013 | | 2013 | 2016-10-07T01:03:50Z |
| github.com-localstack-localstack_-_2023-09-30_01-52-12 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline :zap: Join the LocalStack Insiders program to help us shape the future of LocalStack! Test drive new features & engage in conversations with us so we can learn from your use cases :zap: LocalStack provides an easy-to-use test/mocking framework for developing cloud applications. Overview • Install • Example • Run • Usage • Releases • Contributing 📖 Docs • 💻 Pro version • ☑️ LocalStack coverage Overview LocalStack is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack s; | 2023 | 2023-09-30T05:53:41Z |
| CIA Reading Room cia-rdp83m00914r002300100097-4: PUBLICATION OF UNCLASSIFIED ANALYSIS | Approved For Release 2007/03/09: CIA-RDP83MOO914R002300100097-4 .xcacutlve Rayic4ig FEB 17 4 05 P4 ?8L MEMORANDUM FOR: Director of Central Intelligence OEXA 82-0455/1 17 FEB 1982 Director, ice o External Affairs SUBJECT: Publication of Unclassified Analysis 1. Action. Requested: Sign the attached letter to Gustav F. Papanek, Boston University, President of the Association for .Comparative Economic Studies. 2. Background: Pananek wrote you on 5 February 1982 to ask that you resume release of unclassified. CIA analysis to the public. (Tab A) The attached proposed response is consistent with your 20 January 1982 letter to Messrs. Becker and Horelick at the.Rand Corporation, and a more recent letter Bob Gates sent to Dr. Grossman of the University.of California on the same subject. (Tab B) It has been adjusted to avoid the look of a form letter, however, since it is likely that these people exchange letters with each other. 3. Recommendation: Sign the attached letter. U -:, Ui1- Director o; | 1982 | 2025-02-22T15:23:14Z |
| CIA Reading Room cia-rdp84b00148r000100370001-5: OEXA RECORDS MANAGEMENT | Charles E. Wilson Chief, Public Affairs Division OEXA Records Management 1. Action Requested: Transfer primary PAD records management responsibility to OEXA Registry. 2. Background: Since PA ceased to exist as an Independent Office and became a Division in OEXA, PAD has nevertheless retained a Records Management Officer (RMO) and primary responsibility for this function. Since this is normally a Registry function, we are probably overdue in transferring it. I understand the OEXA Registry is already RMO for LLD. It seems to me that in a perfect world PAD would retain day-to-day maintenance of its decentralized files, but the Registry would assume responsi- bility for such things as reporting annual volume surveys, maintaining file retirement schedules, file renumbering projects, and the like. 3. Recommendation: Request OEXA Administrative Officer's assistance in establishing the Chief, OEXA Registry as RMO for all of OEXA and in transferring PAD's responsibility. We are prepared to assi; | 1982 | 2025-02-19T12:51:25Z |
| github.com-DovAmir-awesome-design-patterns_-_2022-11-09_07-18-54 | A curated list of software and architecture related design patterns. Awesome Software and Architectural Design Patterns A curated list of software and architecture related design patterns. Software design pattern - A general, reusable solution to a commonly occurring problem within a given context in software design. It is a description or template for how to solve a problem that can be used in many different situations. Contents Programming language design patterns General Architecture Cloud Architecture Serverless Architecture Micro services & Distributed Systems Internet of things Big Data Databases and storage Docker and DevOps Mobile Front End Development Security Programming Language Design Patterns AngularJS design patterns C# design-patterns design-patterns-for-human - ultra simplified explanation to design patterns. Design Patterns Library C++ design-patterns Closure design-patterns Go design-patterns Java sourcemaking - patterns and anti patterns. oodesign - patterns catalog ; | 2022 | 2022-11-09T18:39:55Z |
| github.com-aws-aws-cdk_-_2020-03-31_08-47-24 | The AWS Cloud Development Kit is a framework for defining cloud infrastructure in code AWS Cloud Development Kit (AWS CDK) The AWS Cloud Development Kit (AWS CDK) is an open-source software developmentframework to define cloud infrastructure in code and provision it through AWS CloudFormation. It offers a high-level object-oriented abstraction to define AWS resources imperatively usingthe power of modern programming languages. Using the CDK’s library ofinfrastructure constructs, you can easily encapsulate AWS best practices in yourinfrastructure definition and share it without worrying about boilerplate logic. The CDK is available in the following languages: JavaScript, TypeScript ( Node.js ≥ 10.3.0 ) Python ( Python ≥ 3.6 ) Java ( Java ≥ 8 and Maven ≥ 3.5.4 ) .NET ( .NET Core ≥ 3.1 ) Developer Guide | CDK Workshop | Getting Started | API Reference | Examples | Getting Help | RFCs | Roadmap Developers use the [CDK framework] in one of thesupported programming languages to d; | 2020 | 2020-03-31T09:11:59Z |
| A high concentration of genistein down-regulates activin A, Smad3 and other TGF-? pathway genes in human uterine leiomyoma cells. | This article is from Experimental & Molecular Medicine , volume 44 . Abstract Previously, we found that high doses of genistein show an inhibitory effect on uterine leiomyoma (UtLM) cell proliferation. In this study, using microarray analysis and Ingenuity Pathways Analysis™, we identified genes (up- or down-regulated, ≥ 1.5 fold, P ≤ 0.001), functions and signaling pathways that were altered following treatment with an inhibitory concentration of genistein (50 µg/ml) in UtLM cells. Downregulation of TGF-β signaling pathway genes, activin A, activin B, Smad3, TGF-β2 and genes related to cell cycle regulation, with the exception of the upregulation of the CDK inhibitor P15, were identified and validated by real-time RT-PCR studies. Western blot analysis further demonstrated decreased protein expression of activin A and Smad3 in genistein-treated UtLM cells. Moreover, we found that activin A stimulated the growth of UtLM cells, and the inhibitory effect of genistein was partiall; | 2012 | 2014-10-28T19:53:56Z |
| Analytical Geometry | | 1980 | 2023-12-22T12:13:27Z |
| CIA Reading Room cia-rdp83m00914r002700200048-3: REQUEST FOR SPEAKING ENGAGEMENT - CHIEF EXECUTIVE S FORUM, PALM SPRINGS, CALIFORNIA | Approved For Release 2007/03/15: CIA-RDP83M0091 2-fR009g~l~ 3 OEXA 82-0226 MEMORANDUM FOR: Director of Central Intelligence Director, fT-ice o External Affairs STAT SUBJECT: Request for Speaking Engagement - Chief Executive's Forum, Palm Springs, California 1. Action Requested: Regret an invitation to speak to the Chief Executive's Forum in Palm Springs on 21 February. 2. Background: Public Affairs received this invitation by telephone from Leo Greenland, Program Chairman of the Chief Executive's For m. A formal invitation is in the mail. Greenland says you met at home in New York. You are committed to Palm Beach 19-23 February. 3. Recommendation: To ease Greenland's problem in arranging for another speaker, authorize Public Affairs to telephone your regrets. Director of Central Intelligence (Date) /s/ _ - ___ T2- Director of Central Intelligence (Date) STAT STAT OEXA/CEW/cdk/27 Jan 82/x7676 Distribution: Orig - Addressee DDCI - ER 1 - D/OEXA 1 - OEXA Registry 1 - C/PAD (To Be Returned; | 1982 | 2025-02-22T15:15:54Z |
| CELEBRITY MOTOR CAR, LLC v. CDK GLOBAL, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2025-06-17T09:38:39Z |
| DTIC ADA372217: Cyclin D1, Anchorage-Independent Growth and Breast Cancer. | Derangements in the cell cycle machinery contribute to uncontrolled cell growth and tumorigenesis. Regulators of GI progression including cyclin D1 and the cyclin-dependent kinase inhibitors p21 and p27 appear to be of particular importance in the pathogenesis of breast cancer. Our data show that the overexpression of cyclin D1 leads to a compensatory increase in the cdk inhibitor p21, and suggest that this increase can weaken the value of cyclin D1 overexpression as a diagnostic indicator. We suggest that aggressive breast cancer will involve both (1) overexpression of cyclin D1 and (2) the failure to undergo a compensatory upregulation of cdk inhibitors. The specific aims are designed to test these hypotheses in cell culture models, nude mice, and breast cancer biopsies. We have thus far determined that p21- null fibroblasts are adhesion-dependent and suitable for use to study the role of p21 in negating the effect of cyclin D1 overexpression on anchorage-independent cell cycle progr; | 1998 | 2018-04-26T23:30:00Z |
| Tumor-suppressing viruses, genes, and drugs : innovative cancer therapy approaches | 1 online resource (xv, 425 pages) : // Includes bibliographical references and index // Ch. 1. Oncolytic viruses: virotherapy for cancer -- Ch. 2. Reovirus therapy of Ras-associated cancers -- Ch. 3. Oncolytic herpes simplex virus (G207) therapy: from basic to clinical -- Ch. 4. p53 and its targets -- Ch. 5. Prospects for tumor suppressor gene therapy: RB as an example -- Ch. 6. CDK inhibitors: genes and drugs -- Ch. 7. CDK inhibitors: small molecular weight compounds -- Ch. 8. NF1 and other RAS-binding peptides -- Ch. 9. Cytoskeletal tumor suppressor genes -- Ch. 10. TGF-[beta] signaling and carcinogenesis -- Ch. 11. DAN gene -- Ch. 12. Design of hammerhead ribozymes and allosterically controllable maxizymes for cancer gene therapy -- Ch. 13. Inhibitors of angiogenesis -- Ch. 14. Geranylgeranylated RhoB mediates the apoptotic and antineoplastic effects of farnesyltransferase inhibitors: new insights into cancer cell suicide -- Ch. 15. RAS binding compounds -- Ch. 16. Actin-binding dru; | 2002 | 2020-05-15T01:03:07Z |
| DTIC ADA443059: Suppression of Prostate Cancer by PTEN and p18(INK4C) | The Rb pathway suppresses tumorigenesis by constraining G1 cell cycle progression. Functional inactivation or reduction of this pathway is a common event found in many types of human tumors. To test how the Rb pathway interacts with other cellular pathways in tumor suppression, we characterized mice with combined mutations in the CDK inhibitor p18 (sub Ink4c) and the lipid phosphatase Pten, which regulates cell growth and survival. Thep18-/-;Pten +/-double mutant mice develop prostate cancer in the anterior and dorsolateral lobes and thyroid C cell tumors with nearly complete penetrance, and pituitary tumors in both the anterior and intermediate lobes. AKT/PKB, an oncoprotein and downstream substrate of PTEN, was activated and accumulated at the plasma membrane in Pten+i. cells, and further activated and accumulated in the nucleus in p18-/-;Pten+/- tumor cells, suggesting a negative regulation of AKT by the Rb pathway. The remaining wildtype allele of Pten was lost at a high frequency ; | 2005 | 2018-05-31T00:40:44Z |
| github.com-sindresorhus-awesome_-_2023-06-23_22-54-41 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app Hyperduck Send links from your iOS devices to your Mac (better than AirDrop) My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. API to get search engine results with ease. API to get search engine results with ease. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Development E; | 2023 | 2023-06-24T23:56:50Z |
| Formula Sports Cars, Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2024-07-01T09:06:32Z |
| Zarzuelas y temas clásicos de España | Tracklist: 1. El Baile de Luis Alonso - Giménez 2. Sevilla - Albéniz 3. Castilla - Albéniz 4. Danza Espaänola No. 5 «AndaluzaãA - Granados 5. La Dolores (Jota) - Bretón 6. Suspiros de Espaäna - Alvarez 7. Agua, Azucarillos y Aguardiente - Chueca 8. Doäna Francisquita (Fandango) - Vives 9. Las Carretas del Rocio - Monreal 10. Asturias - Albéniz 11. Sacromonte - Turina 12. Bolero - Popular | 1988 | 2024-08-05T08:58:59Z |
| Het Utrechts Archief 807733 | Het Utrechts Archief catalog number: 807733 Description (Dutch): Afbeelding van de CDk-bak van het ontspoorde electrische treinstel nr. 302 (mat. 1940) van de N.S. bij de spoorbrug over de Haven te Maassluis. | 1956 | 2021-02-26T01:03:42Z |
| DTIC ADB240661: Oncogenic Functions of cdK4 and cdK6 | Cancer cells often contain disruptions in the transition from GL phase to S phase. The retinoblastoma protein (pRb) is one negative regulator of cellular proliferation. Many breast cancers retain functional pRb and therefore must use other mechanisms to alleviate the tumor-suppressive function of pRb. One common mechanism to circumvent pRb function is amplification of the GL phase cyclin dependent kinases (cdk), cdk4 and cdk6. Cyclin dependent kinase 4 and cdk6 are thought to have redundant functions as pRb regulators, despite an increasing body of evidence suggesting that certain tumor types specifically activate either cdk4 or cdk6. This implies that either the function or the regulation of these kinases may be different in different cell types. Data presented here show that cdk4 and cdk6 have different abilities to drive the cell cycle-from GL into S phase in the osteosarcoma cell line, U2OS. Understanding differential regulation of these two kinases and their potentially different ; | 1998 | 2018-03-03T10:06:08Z |
| github.com-localstack-localstack_-_2022-11-12_23-39-58 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline! LocalStack provides an easy-to-use test/mocking framework for developing Cloud applications. Overview • Install • Example • Run • Usage • Changelog • Contributing – 📖 Docs • 💻 Pro version • ☑️ Feature coverage • 📢 Announcements Overview LocalStack 💻 is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack supports a growing number of AWS services, like AWS Lambda, S3, Dynamodb, Kinesis, SQS, SNS, and many more! The Pro version of LocalStack supports additiona; | 2022 | 2022-11-13T09:19:09Z |
| CDK Global, LLC al v. Tulley Automotive Group, Inc. | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2017-07-24T21:20:07Z |
| Swift Flies the Falcon | | 1939 | 2023-11-06T18:03:35Z |
| Persuading science : the art of scientific rhetoric | xi, 212 p. : 24 cm // Includes bibliographical references and index | 1991 | 2023-12-23T17:00:10Z |
| github.com-debezium-debezium_-_2021-12-10_11-35-09 | Change data capture for a variety of databases. Please log issues at https://issues.redhat.com/browse/DBZ. Copyright Debezium Authors.Licensed under the Apache License, Version 2.0 .The Antlr grammars within the debezium-ddl-parser module are licensed under the MIT License . English | Chinese | Japanese Debezium Debezium is an open source project that provides a low latency data streaming platform for change data capture (CDC). You setup and configure Debezium to monitor your databases, and then your applications consume events for each row-level change made to the database. Only committed changes are visible, so your application doesn't have to worry about transactions or changes that are rolled back. Debezium provides a single model of all change events, so your application does not have to worry about the intricacies of each kind of database management system. Additionally, since Debezium records the history of data changes in durable, replicated logs, your application can be stoppe; | 2021 | 2021-12-10T12:09:39Z |
| DTIC ADA410428: Development of Inhibitors That Selectively Disrupt Substrate Recognition by Cyclin-Dependent Kinases | Upregulation of cyclin/cdk activity and the resulting deregulation of the cell cycle is a common feature in the malignant transformation of breast epithelial cells and thus makes cyclin/cdks an attractive target for drug design. The long-term goal of our work is to develop inhibitors which inhibit cyclin/cdk activity by disrupting the interaction between cyclins and their substrates, an association that requires a sequence motif in the substrate termed a Cy motif. Cy or RXL motifs are general purpose motifs for the interaction of cellular factors with cyclins. Recent work in our laboratory has shown that these motifs are critical determinants of both substrate recognition and specificity and function by targeting molecules to particular cyclin/cdk complexes. During the first year of grant support, we have made significant advancements into understanding substrate recognition by cyclin-dependent kinases. This work provides the framework for the development of Cy motif-derived peptides a; | 2002 | 2018-05-11T22:33:13Z |
| DTIC ADA443026: Radiation Sensitization in Breast Cancer via Targeting Survivin Expression | We proposed to determine whether overexpression- of surviving results in radio resistance and the possible mechanisms; whether irradiation down regulates p34(CDC2) and its mechanism in vascular endothelium and whether CDK (cyclin dependent kinase) inhibitors sensitize it to radiation injury; the mechanism of surviving- deregulation in breast cancer and whether inhibition of surviving or its regulator, p34(CDC2) abolishes radio resistance. We found that overexpression of surviving leads to radiation resistance and CDK inhibitors result in radiosensitization. We also found that deregulation of surviving in breast cancer is mediated by Stat3 (Signal transducer and activator of transcription). Co-inhibition of surviving and Stat3 results in significantly increased sensitization of breast cancer. In the next two years, we will determine the biological significance of combining surviving inhibitors or CDK inhibitors with radiotherapy in xenograft models of breast cancer. The proposed study w; | 2005 | 2018-05-30T23:48:34Z |
| Pathfinders in Medicine. | | 1929 | 2023-12-22T15:43:03Z |
| The Future of Public Access TV and The Internet | Mark Cooper of the Consumer Federation of America speaks with local independent radio host John Grebe about current bills in Congress affecting the future of Public Access Television and the Internet. We also hear from Jason Crow, Access Coordinator of Cambridge Community Television and Michael Eisenmenger of Manhattan Neighborhood Network about how pending legislation in Congress takes away local control of media and places more power in the hands of Big Cable and Telephone companies. Click here to listen to the ACMEBoston Podcast February 11, 2006. Also discussed is the issue of Network Neutrality which Free Press , the national media reform organization, describes as "the guiding principle of the Internet that fosters open competition and innovation, while preserving the independence and accessibility of the World Wide Web" - Free Press, Net Freedom Now . To take a closer look at these issues, we'll hear John Grebe's interview from his program, "Sounds of Dissent" broadcast live on ; | 2006 | 2006-07-27T08:21:29Z |
| DTIC ADA474451: Mechanism of Antineoplastic Action of Bisperoxovanadium Compound | This work describes studies into the mechanism of action of bisperoxovanadium (bpVs) compounds and into the basic biology and regulation of Cdc25A phosphatase. The bpVs cause phase-specific cell cycle arrest (G1/S), dose-dependent inhibition of Cdk activity, and persistent Rb hypophosphorylation upon release from serum starvation, consistent with Cdc25A inhibition. Further, they cause p53-independent apoptosis. Oxidative stress and DNA damage do not appear to be involved in their mechanism of action, given that: p53 is not induced by bpV(Me2Phen); p53 and p21 status do not affect IC50; depletion of glutathione or supplementation with antioxidants does not affect IC50, in contrast to other heavy metal-based agents. With respect to regulation, the Cdc25A nuclear localization signal (NLS) was identified and characterized. Data suggest that phosphorylation of S292, adjacent to the NLS, may promote nuclear localization. In the unperturbed cell cycle, S292 phosphorylation, a Chk1/2 target, a; | 2005 | 2018-06-15T10:53:58Z |
| github.com-dabit3-awesome-aws-amplify_-_2021-02-13_23-48-59 | Curated list of AWS Amplify Resources Awesome AWS Amplify curates the best AWS Amplify, tools, tutorials, articles and more. PRs are welcome! Check out the Amplify Discord server Getting Started Github Documentation Workshops Serverless GraphQL API with AppSync and DynamoDB AWS Amplify Photo Sharing Workshop Next.js AWS Amplify Workshop Building real-time applications with React, GraphQL & AWS AppSync Building Mobile Applications with React Native & AWS Amplify AWS Amplify UnicornFlix Workshop (Video on Demand) AWS Amplify UnicornTrivia Workshop (Live streaming video) Tutorials - Blogs & tutorials General blogs & tutorials Full Stack Cloud Development with AWS Amplify TensorFlow.js + AWS Amplify 10 Minute Tutorial: Creating a Serverless Express Web Server & API ⚡️ 10 Ways to Use Serverless Functions Real quick GraphQL service with AWS Amplify & Appsync Visualizing Focus with Neurosity's Notion and AWS Amplify Build a Music Sharing App with Amazon S3 and AWS Amplify Introducing Conf; | 2021 | 2021-02-22T13:28:20Z |
| Novel structural features of CDK inhibition revealed by an ab initio computational method combined with dynamic simulations | The rational development of specific inhibitors for the ~500 protein kinases encoded in the human genome is impeded by a poor understanding of the structural basis for the activity and selectivity of small molecules that compete for ATP binding. Combining classical dynamic simulations with a novel ab initio computational approach linear-scalable to molecular interactions involving thousands of atoms, we have investigated the binding of five distinct inhibitors to the cyclin-dependent kinase CDK2. We report here that polarization and dynamic hydrogen bonding effects, so far undetected by crystallography, affect both their activity and selectivity. The effects arise from the specific solvation patterns of water molecules in the ATP binding pocket or the intermittent formation of hydrogen bonds during the dynamics of CDK/inhibitor interactions and explain the unexpectedly high potency of certain inhibitors such as 3-(3H-imidazol-4-ylmethylene)-5-methoxy-1,3-dihydro-indol-2-one (SU9516). T; | 2008 | 2013-09-17T19:30:51Z |
| DTRASH10 - Bastards United - Bastards United | This is a killer collection of breakneck headbanger digital thrash music. Bastards United have are a complete digicore band with guitarists, MCs and program thrashers. Straight from the Netherlands, BU collaborates on some slammin' tracks with Rabies/CDK and b57 from CPUWAR in the mix! | 1999 | 2008-04-19T16:24:14Z |
| Los Merengazos Del Año Vol.11 | Tracklist: 1. Que Buenas Son Las Fiestas - Pochy Y Su Cocoband 2. Algo Le Di Yo - Bonny Cepeda Y Su Orquesta 3. Baby Baby - Dimanchy 4. Volviendome Tu - Dioni Fernández Y El Equipo 5. Mambo - Los Hermanos Mercedes 6. La Chica Trueno - Yanko 7. Tu Eres Mi Hembra - Monchy Capricho 8. Macarena - Yarumba 9. El Macho - Nelson Gil 10. Ella Me Da - Grupo Karamba 11. A Fuego Lento - Feliz Cumbre 12. Noche De Luna - Lisandro Meza | 1994 | 2024-04-14T23:22:07Z |
| Pollitas de Cuenta | Tracklist: 1. Pollitas de cuenta 2. La pelirroja 3. Esperanza Valero 4. La entalladita 5. Los traficantes 6. Rosita la Morena 7. La bella coqueta 8. La hiena asesina 9. Lupe la Gèuera 10. Juana Collares | 2001 | 2025-03-12T09:43:38Z |
| github.com-sottlmarek-DevSecOps_-_2022-01-15_03-45-55 | Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevSecOps scope. Table of Contents Def; | 2022 | 2022-01-15T10:00:54Z |
| CDKB2 is involved in mitosis and DNA damage response in rice. | This article is from The Plant Journal , volume 69 . Abstract DNA damage checkpoints delay mitotic cell-cycle progression in response to DNA stress, stalling the cell cycle to allow time for repair. CDKB is a plant-specific cyclin-dependent kinase (CDK) that is required for the G2/M transition of the cell cycle. In Arabidopsis, DNA damage leads the degradation of CDKB2, and the subsequent G2 arrest gives cells time to repair damaged DNA. G2 arrest also triggers transition from the mitotic cycle to endoreduplication, leading to the presence of polyploid cells in many tissues. In contrast, in rice (Oryza sativa), polyploid cells are found only in the endosperm. It was unclear whether endoreduplication contributes to alleviating DNA damage in rice (Oryza sativa). Here, we show that DNA damage neither down-regulates Orysa;CDKB2;1 nor induces endoreduplication in rice. Furthermore, we found increased levels of Orysa;CDKB2;1 protein upon DNA damage. These results suggest that CDKB2 functions; | 2011 | 2014-10-24T08:09:52Z |
| High-Throughput Screening Reveals Alsterpaullone, 2-Cyanoethyl as a Potent p27Kip1 Transcriptional Inhibitor. | This article is from PLoS ONE , volume 9 . Abstract p27Kip1 is a cell cycle inhibitor that prevents cyclin dependent kinase (CDK)/cyclin complexes from phosphorylating their targets. p27Kip1 is a known tumor suppressor, as the germline loss of p27Kip1 results in sporadic pituitary formation in aged rodents, and its presence in human cancers is indicative of a poor prognosis. In addition to its role in cancer, loss of p27Kip1 results in regenerative phenotypes in some tissues and maintenance of stem cell pluripotency, suggesting that p27Kip1 inhibitors could be beneficial for tissue regeneration. Because p27Kip1 is an intrinsically disordered protein, identifying direct inhibitors of the p27Kip1 protein is difficult. Therefore, we pursued a high-throughput screening strategy to identify novel p27Kip1 transcriptional inhibitors. We utilized a luciferase reporter plasmid driven by the p27Kip1 promoter to transiently transfect HeLa cells and used cyclohexamide as a positive control for non; | 2014 | 2014-10-23T23:51:04Z |
| DTIC ADA385811: The Regulation of Human Cyclin E Protein Levels by the Ubiquitin Proteolytic Pathway | Cyclin E is an unstable protein that is degraded in a ubiquitin- and proteasome-dependent pathway. Two factors stimulate cyclin E ubiquitination in vivo: when it is free of its CDK partner, and when it is phosphorylated on threonine 380. We pursued the first of these pathways by using a two-hybrid screen to identify proteins that could bind only to free cyclin E. This resulted in the isolation of human Cul-3, a member of the cullin family of E3 ubiquitin-protein ligases. We found that Cul-3 was bound to cyclin E but not to cyclin E-Cdk2 complexes in mammalian cells, and that overexpression of Cul-3 increased ubiquitination of cyclin E but not other cyclins. Conversely, deletion of the Cul-3 gene in mice caused increased accumulation of cyclin E protein, and had cell-type specific effects on S phase regulation. In the extraembryonic ectoderm, where cells undergo a standard mitotic cycle, there was a greatly increased number of cells in S phase. In the trophectoderm, where cells go throu; | 1999 | 2018-04-30T11:20:49Z |
| The Savvy and The Chic Vol.8: Playa *compiled by Hektor Thillet* | The Savvy and The Chic Vol.8: Playa *compiled by Hektor Thillet* *Escape to a hidden oasis of tropical bliss and musical enchantment* WORD Summer is finally ahead; is time to shed all worries and complications and be reborn with the burning sun rising like a mighty phoenix. This installment of The Savvy and the Chic comes as an oasis, a mental retreat from a personal hiatus of much earthly turbulence. A sonic beach of clear skies, sandy shores, and purifying waters to cleanse the body and soul. I thank everyone who lent a hand in the production of this album or inspired it in some shape or form. Thanks to the wonderful artists over at ccmixter.org who make these series possible with their wonderful work. Last but not least – Thank you for listening! I hope this offering finds you in a Buddha state of mind where every misdeed towards life, nature and love is forgotten if not forgiven; and the good in all things is treasure. Enjoy. CD1 - MAREJADA 1 Beaches (Texas Radio Fish) 2 Just One; | 2011 | 2011-05-17T17:46:02Z |
| The Savvy & the Chic Vol.5: The Rules of Social Decency | Word "We learn that even a good cause can prove as bad as its conflicting source, when we have triumph and are left with the thirst of a mere self-gratifying crusade. The rules of social decency..." - Hektor Thillet I thank the artist at ccmixter.org, and you - the listener. CD TRACK LISTING 1 Luxuria 2 The Most Terrifying Night 3 An Infidelic Symphony. Blood, Love & Family 4 Guetto Opera 5 One Moment 6 Flora Glamour 7 Buddz In The Hood 8 Move Your Body 9 FAYE 10 Late Night 11 Adopt a Black Dog 12 Deflated & Alone 13 There's a Way 14 The Rules of Social Decency 15 All the Beet Just 16 The Evil Inside 17 Ophelia's Song 18 Watch That sound TRACK CREDITS IN DETAIL OF COLLABORATION 1 Luxuria - Hektor Thillet ft. KCentric, J.Lang, Anomaly Jonez 2 The Most Terrifying Night (Hektor Thillet ft. Grapes 3 An Infidelic Symphony. Blood, Love & Family - Loveshadow ft. FORENSIC, Mykleanthony & DJ Vadim 4 Guetto Opera - Hektor Thillet ft. Soda, Eshar & KCentric 5 One Moment CDK ft. Antony Raijekov & ; | | 2010-04-16T07:09:54Z |
| The Early theory of equations : on their nature and constitution : translations of three treatises | 218 p. ; 23 cm // On the recognition of equations / by François Viète -- A new discovery in algebra / by Albert Girard -- On the nature and constitution of equations / by Florimond de Beaune | 1986 | 2023-12-22T11:17:45Z |
| [CDK 014] Assault | An assault on the senses? An assault on modern society? An assault on South Arctic (I and II)? An assault on old video gaming equipment? Whatever the Assault, it’s gonna assault your ears – in the best way possible! Goatslacker is a Floridian chiptuner who also uses the occasional keyboards ‘n’ drums for his music. He has a GSOH, likes walks in the parks and cinema and WLTM a person with similar interests in phat basslines and tight drums. | 2008 | 2019-12-06T22:45:14Z |
| github.com-sindresorhus-awesome_-_2022-01-21_21-53-36 | 😎 Awesome lists about all kinds of interesting topics My Actions app is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab; | 2022 | 2022-01-22T00:52:52Z |
| github.com-sindresorhus-awesome_-_2023-10-26_11-42-32 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app One Task Stop procrastination and get stuff done by focusing on one task at a time My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. API to get search engine results with ease. API to get search engine results with ease. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Develop; | 2023 | 2023-10-26T13:33:54Z |