| Title | Description | Published | Added |
| The three Jameses | | 1962 | 2025-05-22T16:21:27Z |
| Second international meeting of the international society for neurochemistry | | 1969 | 2025-09-08T04:17:18Z |
| Scientists In Organizations | | 1966 | 2025-09-11T18:21:23Z |
| CIA Reading Room cia-rdp62-00634a000200010059-3: CIA ELINT TRAINING PROGRAM INITIAL REPORT OF THE EAS SUB-COMMITTEE ON TRAINING 17 DECEMBER 1958 | Approved For Releas'2005/11/17 : CIA-RDF CONFIDENTIAL CIA ELINT TBAINING PROGRAM Initial Report of the EAC Sub-Committee on Training 17 December 1958 A. BACKGROUND: The EAC Sub-Committee on ELINT Training has held three meetings during which the following points were considered and, agreed upon: 1. Purpose of a CIA FLINT Training Program a. To prepare technical personnel for assignments to specific ELINT activities when and where required by the Agency ELINT Program. b. To acquaint non-technical personnel not partici- pating directly in the Agency ELINT Program with the capa- bilities and potential of DINT as a scientific intelligence tool. 2. Categories of personnel. needing training Intercept Operators; Data Reduction Personnel Maintenance Engineers R&D Engineers Intelligence Analysts Operations Personnel Administrators 3. Methods of training Document No. no CN, N(!E tat class. ^ DECI,AST,-,rrD Class. C"',1.r- aC: Aut: Date: a. Internal CIA courses b. On-the-job (training site and op; | 1958 | 2024-05-26T01:59:38Z |
| CIA Reading Room cia-rdp83m00914r002700200048-3: REQUEST FOR SPEAKING ENGAGEMENT - CHIEF EXECUTIVE S FORUM, PALM SPRINGS, CALIFORNIA | Approved For Release 2007/03/15: CIA-RDP83M0091 2-fR009g~l~ 3 OEXA 82-0226 MEMORANDUM FOR: Director of Central Intelligence Director, fT-ice o External Affairs STAT SUBJECT: Request for Speaking Engagement - Chief Executive's Forum, Palm Springs, California 1. Action Requested: Regret an invitation to speak to the Chief Executive's Forum in Palm Springs on 21 February. 2. Background: Public Affairs received this invitation by telephone from Leo Greenland, Program Chairman of the Chief Executive's For m. A formal invitation is in the mail. Greenland says you met at home in New York. You are committed to Palm Beach 19-23 February. 3. Recommendation: To ease Greenland's problem in arranging for another speaker, authorize Public Affairs to telephone your regrets. Director of Central Intelligence (Date) /s/ _ - ___ T2- Director of Central Intelligence (Date) STAT STAT OEXA/CEW/cdk/27 Jan 82/x7676 Distribution: Orig - Addressee DDCI - ER 1 - D/OEXA 1 - OEXA Registry 1 - C/PAD (To Be Returned; | 1982 | 2025-02-22T15:15:54Z |
| Shoreline City Council Regular Meeting - December 2, 2024 | # Shoreline City Council Regular Meeting - December 2, 2024 The Shoreline City Council met on Monday, December 2, 2024, at 7:00 p.m. in the Council Chamber at Shoreline City Hall. The meeting focused on two major study items: the adoption of Ordinance No. 1026 updating the 2024 Comprehensive Plan and Ordinance No. 1027 updating the Zoning Map and Development Code to implement the plan. The council heard extensive public comment, discussed staff presentations, and set the stage for action at the December 16 meeting. ### Consent Calendar - **Approved unanimously (6-0):** The consent calendar included approval of special meeting minutes of November 4, 2024, regular meeting minutes of November 18, 2024, and authorization for the City Manager to execute change orders increasing the contract with CDK Construction Inc. by $850,000 to a maximum of $7,912,540 for the Ballinger Maintenance Facility Project. ### Public Comments & Testimony - **Jill Chapman**, Shoreline resident, expressed concern; | 2024 | 2026-09-03T10:16:24Z |
| High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a. | This article is from Microbiology , volume 158 . Abstract The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry. The rapid increase of resistance to therapeutic agents, as well as the expense of vaccination with live attenuated vaccines, requires the development of new effective treatments for coccidiosis. Because of their key regulatory function in the eukaryotic cell cycle, cyclin-dependent kinases (CDKs) are prominent drug targets. The Eimeria tenella CDC2-related kinase 2 (EtCRK2) is a validated drug target that can be activated in vitro by the CDK activator XlRINGO (Xenopus laevisrapid inducer of G2/M progression in oocytes). Bioinformatics analyses revealed four putative E. tenella cyclins (EtCYCs) that are closely related to cyclins found in the human apicomplexan parasite Plasmodium falciparum. EtCYC3a was cloned, expressed in Escherichia coli and purified in a co; | 2012 | 2014-10-28T23:41:32Z |
| Applications of the InChI in cheminformatics with the CDK and Bioclipse. | This article is from Journal of Cheminformatics , volume 5 . Abstract Background: The InChI algorithms are written in C++ and not available as Java library. Integration into software written in Java therefore requires a bridge between C and Java libraries, provided by the Java Native Interface (JNI) technology. Results: We here describe how the InChI library is used in the Bioclipse workbench and the Chemistry Development Kit (CDK) cheminformatics library. To make this possible, a JNI bridge to the InChI library was developed, JNI-InChI, allowing Java software to access the InChI algorithms. By using this bridge, the CDK project packages the InChI binaries in a module and offers easy access from Java using the CDK API. The Bioclipse project packages and offers InChI as a dynamic OSGi bundle that can easily be used by any OSGi-compliant software, in addition to the regular Java Archive and Maven bundles. Bioclipse itself uses the InChI as a key component and calculates it on the fly whe; | 2013 | 2014-10-27T02:14:25Z |
| DTIC ADA331989: Modulation of Cyclin Expression by c-Myc in Malignant and Nonmalignant Mammary Epithelial Cells. | The purpose of this grant was to support predoctoral training on an experimental model relevant to breast cancer etiology. Specifically, we explored the multifactorial nature of the interaction a growth factor (TGFalpha, which is commonly expressed both in benign and malignant proliferative disease of the human breast) and an oncogene (c-myc, whose gene is amplified and whose protein is inappropriately expressed in 20-30% of human breast tumors. Using a transgenic mouse model we observed that co-expression of these two genes was remarkably synergistic for onset and progression of cell survival and proliferation. While mye induced both p53 and bax death-promoting genes, TCFalpha promoted cell survival by inducing Bc1XL. In terms of the cell cycle, mye shortened G1 by modulating cyc1lin E, p27, and cdc25A, which activated cdk-2 and inactivated Rb. Thus, the interaction of TGFalpha and myc promoted shortened, aberrant cycles resulting in survival of genetically aberrant cells. | 1997 | 2018-04-09T05:12:15Z |
| Flourescent Protein Tracing | | 1962 | 2025-09-12T10:44:29Z |
| Pterostilbene Simultaneously Induced G0/G1-Phase Arrest and MAPK-Mediated Mitochondrial-Derived Apoptosis in Human Acute Myeloid Leukemia Cell Lines. | This article is from PLoS ONE , volume 9 . Abstract Background: Pterostilbene (PTER) is a dimethylated analog of the phenolic phytoalexin, resveratrol, with higher anticancer activity in various tumors. Herein, the molecular mechanisms by which PTER exerts its anticancer effects against acute myeloid leukemia (AML) cells were investigated. Methodology and Principal Findings: Results showed that PTER suppressed cell proliferation in various AML cell lines. PTER-induced G0/G1-phase arrest occurred when expressions of cyclin D3 and cyclin-dependent kinase (CDK)2/6 were inhibited. PTER-induced cell apoptosis occurred through activation of caspases-8-9/-3, and a mitochondrial membrane permeabilization (MMP)-dependent pathway. Moreover, treatment of HL-60 cells with PTER induced sustained activation of extracellular signal-regulated kinase (ERK)1/2 and c-Jun N-terminal kinase (JNK)1/2, and inhibition of both MAPKs by their specific inhibitors significantly abolished the PTER-induced activati; | 2014 | 2014-10-06T23:46:41Z |
| CIA Reading Room cia-rdp78-04722a000300030030-9: OPERATIONS DIRECTORATE SUPPORT OFFICERS MEETING 21 AUGUST 1974 | Approved For i T ease 2~6-T/ 14 131 &N Cdk 04722A&300030030-9 21 August 1974 1. Items of interest from the DDO Staff Meeting - 21 August 25X1A a. attended his first meeting as Chief, EUR. Mr. ill attend as 25X1A Special Assistant (probably to be known as SAR). b. Cost of Paper. Last week it was brought to Mr. Nelson's attention that a great deal of paper work is required to obtain DCI approval for visits of Ambassadors or other VIP's. This was discussed with the Director, and Mr. Colby said he would be willing to accept a hand-written memo on yellow paper. Consequently, it is now established policy that internal documentation need not be a perfect manuscript; corrections are acceptable. Anything going outside the Agency should continue to be a perfect manuscript. During the discussion it was pointed out that a number of actions can be approved with a modest amount of paper work, but that substantial numbers of copies are distributed. Mr. Nelson asked the SSA to conduct a study to deter; | 1974 | 2023-11-16T20:11:08Z |
| CIA Reading Room cia-rdp66b00403r000100360030-7: DEAR MR. CHAIRMAN: | Approved For Release 2005/03/15 : CIA-RDP66B00403R000100360030-7 tb* 3 U 1 e4a b* of **y stan e to you in We at rala+ d "" to C*A s. J S. Ws s Ls1 C 1 OGC / L.C: JOOJ r: cdk 0 & I Addressee I-IG 1 . DD/S I - Comptroiier - Attn: 3 - OGC/LC w/basic iA - Subj. w/basic House Gov't Oper, 1 - Signer - JGOJr. 1 - Chrono. Approved For Release 2005/03/15 : CIA-RDP66B00403R000100360030-7 . -RnPAARQQdQ3RQQQ SENDER WILL CHECK CLASSIFICA ION TOP AND BOTTOM UNCLASSIFIED CONFIDENTIAL SECRET CENTRAL INTELLIGENCE AGENCY OFFICIAL ROUTING SLIP TO NAME AND ADDRESS DATE INITIALS I Le is Counsel 2 DD/Support 3 4 5 6 ACTION DIRECT REPLY PREPARE REPLY APPROVAL DISPATCH RECOMMENDATION COMMENT FILE RETURN CONCURRENCE INFORMATION SIGNATURE Remarks : 1: For information, 2: For action. 00 0UjAIts FOLD HERE TO RE ER FROM: NAME, ADDRESS AN DATE UNCLASSIFIED CONFIDENTIAL SECRET Fo2R 610. 237 Use previous editions Approved For Release 2005/03/15 : CIA-RDP66B00403R000100360030-7 | 2005 | 2024-05-20T07:03:06Z |
| CIA Reading Room cia-rdp90-00077r000100040018-7: PROCUREMENT DIVISION STATISTICS AND WORKING RELATIONSHIPS WITH OFFICE OF COMMUNICATIONS | Declassified in Part -Sanitized Copy Approved for Release 2012/03/23 :CIA-RDP90-000778000100040018-7 STAT STAT "__""...."., '..,."~??"?` ~wr 27 January 1984 '?(O: Nam ,office symbol, rrrm number, .~, . 1. C/PD/OL L -. p royal s Requested (Coordination REMARKS Preparo Reply See Me The D/L is scheduled to speak to the Office of Communications staff meeting group on 5 March and he would like you to supply him with information and statistics relative to your rev 1 of Su~~ nrt to nr and your view of the workin s~?tion between your office and' Would appreciate your input by 24 Fe ruary. STAT STAT DO NOT uss this foam as a RECORD of approvals, concurrences, disposals. clearances, and similar actions FROM: (Name, org, symbol, Agency/Post) Frankie 0-D/L so4i-ioz _< ~p~ Eby cs~ ev. 76) _.:. f+ GPO , tON~ n _ an~_c~o .,~,. - F~YR [at Cdk~ ~m_~~ ene ~s Declassified in Part -Sanitized Copy Approved for Release 2012/03/23 :CIA-RDP90-00077R0~00100040018-7 Declassified in Part - Sanitized Copy Appr; | 1984 | 2026-04-28T20:15:47Z |
| A functional role for Smad7 in sustaining colon cancer cell growth and survival. | This article is from Cell Death & Disease , volume 5 . Abstract Initially identified as an inhibitor of transforming growth factor (TGF)-β mainly owing to its ability to bind TGF-β receptor type I and abrogate TGF-β-driven signaling, Smad7 can interact with additional intracellular proteins and regulate TGF-β-independent pathways, thus having a key role in the control of neoplastic processes in various organs. Genome-wide association studies have shown that common alleles of Smad7 influence the risk of colorectal cancer (CRC), even though the contribution of Smad7 in colon carcinogenesis is not fully understood. In this study, we assessed the expression and role of Smad7 in human and mouse models of sporadic CRC. We document a significant increase of Smad7 in human CRC relative to the surrounding nontumor tissues and show that silencing of Smad7 inhibits the growth of CRC cell lines both in vitro and in vivo after transplantation into immunodeficient mice. Knockdown of Smad7 result; | 2014 | 2014-10-24T02:06:36Z |
| github.com-sindresorhus-awesome_-_2022-07-23_10-37-54 | 😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab, GitHub, and Bitbucket, Gitpod au; | 2022 | 2022-07-23T11:35:40Z |
| Cell cycle control : mechanisms and control | xii, 402 p. : 24 cm // Includes bibliographical references and index // Cell cycle molecules and mechanisms of the budding and fission yeasts / Tim Humphrey and Amanda Pearce -- The plant cell cycle : an overview / John H. Doonan -- The C. elegans cell cycle / Sander van den Heuvel -- Developmental control of growth and cell cycle progression in drosophila / Lisa Swanhart, Jeremy Kupsco, and Robert J. Duronio -- The xenopus cell cycle : an overview / Anna Philpott and P. Renee Yew -- The mammalian cell cycle : an overview / Jane V. Harper and Gavin Brooks -- Synchronization of cell populations in G1/S and G2/M phases of the cell cycle / Jane V. Harper -- Mapping origins of DNA replication in eukaryotes / Susan A. Gerbi -- In situ assay for analyzing the chromatin binding of proteins in fission yeast / Stephen E. Kearsey ... [et al.] -- Application of magnetic beads to purify cells transiently transfected with plasmids encoding short hairpin RNAs / Peter D. Adams -- The cell cycle and v; | 2005 | 2020-05-25T21:59:48Z |
| github.com-localstack-localstack_-_2023-09-30_01-52-12 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline :zap: Join the LocalStack Insiders program to help us shape the future of LocalStack! Test drive new features & engage in conversations with us so we can learn from your use cases :zap: LocalStack provides an easy-to-use test/mocking framework for developing cloud applications. Overview • Install • Example • Run • Usage • Releases • Contributing 📖 Docs • 💻 Pro version • ☑️ LocalStack coverage Overview LocalStack is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack s; | 2023 | 2023-09-30T05:53:41Z |
| github.com-sindresorhus-awesome_-_2022-08-11_12-20-41 | 😎 Awesome lists about all kinds of interesting topics Check out: One Thing — Put a single task or goal in your menu bar My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the clo; | 2022 | 2022-08-18T11:22:09Z |
| github.com-sindresorhus-awesome_-_2022-11-14_11-14-47 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app Favorites Widget Call your favorite people directly from the iPhone Lock Screen My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing u; | 2022 | 2022-11-14T21:57:22Z |
| github.com-localstack-localstack_-_2021-11-19_23-04-44 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline! LocalStack provides an easy-to-use test/mocking framework for developing Cloud applications. Overview • Install • Run • Configure • Play – 📖 Docs • 💻 Pro version • ☑️ Feature coverage • 📢 Announcements Overview LocalStack 💻 is a cloud service emulator that runs in a single container on your laptop or in your CI environment.With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider!Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services,LocalStack helps speed up and simplify your testing and development workflow. LocalStack supports a growing number of AWS services, like AWS Lambda, S3, Dynamodb, Kinesis, SQS, SNS, and many more!The Pro version of LocalStack supports additional APIs and advanced features.You c; | 2021 | 2021-11-20T02:26:30Z |
| CIA Reading Room cia-rdp70-00058r000200100098-1: PUZZLING FOREIGN POLICY OF THE U.S. | FE.B. 1 51962 Approved For Release 1999/09/'-pQ1 .RDP7 United 8tates'T e ro ruby die has rdad in. hiai iodal ,which goes MO A,maxrlcan w psper. head-- haq~_ Cominunlat lined' :"Vtl~ e d ti 4!- .,stay' cra* e iA- OOMDgiW11'k .. Cdk ? bif thin M4 Ctrants: : thy; ''zi ,e4 tent to foreigh.*ld' anti the Congo Leader:' it erptains ywQ s trong atfr pe Vol" of,A oa Yet the "iJnlt d gat- ' t d f th o re e e o .policies which go along with former . Batista government this vast pone, do. Tf a c$dl 1'9 goal di et .4 Yr t 1 1e pt Victory' )endue B +dk a ltfiil Q d ve tIs at gC'tbe ' muiifng ta11i fir .. < ;thd words et etc. have speeches ' men. _~ e "l ode ?tSat~ snatchesf h p_oeeibie' 14%, Dim kTuubaff~ ~*ent-in the T?os rte 's, the l" rnm #? ant i~ic tltt~aoty.. Vital, i o s e a slat t[1gli,~ ? f i'q~M,' Cato ndgixe ex+~ e s 1$ o bf t 1+ . 'e dl 'iral o 1, + # < Uride*rstar-dstr,~ Ikrta eager ~e~ e td l t ' :thew le' n logs ,tn ezontinq otii rj~Y .# tiYea rioltcy a it izas ttt-t era:.+1e tie; era; | 1962 | 2023-08-06T09:52:48Z |
| CIA Reading Room cia-rdp91-00929r000200790054-5: FR:YURKOV D.A. TO:YUR JEV V. | ner. FIz Tvvrdo&,o TnIAw.. Val I I Vo U~AIPScm ftj-, - doiid ft-atcVol I!, No arcrbardcart or *l,-i '.1r:-IVIV of ALM tku Djp~.ndwwca i5fcir, .4ut A14,*,act yomation an U.0 01,16.-t-4tim Ofw1U) tbe Dapwndanov cf tho !-"to of !)&foctor) the of a ~;~3L;Ll aMth-.1-cetran at~4m, 17 7. S. VaTiln, 7. pata~c--Mr, Ytri4r. lVorlor.0 Tala, 'lol -f- No 1,40AV,&j!'JuU." vi, t~wrrzyperv- Zbw T"b rizp '101 X(YM,, Wo 7t (If FbV-Orvv-~hVol I=,reaeustum or sa"tro" In*/44810"We &OdUU*m, by 2. T&. lubevo 5 pp.MULWO We zbw Sam nal %I XXTUI, so O~ 1VA,pp U"-LVA.Amr bwt et Ptasftv M" - T*eb ftlevia& wt, ft 6S" . PanIrob ~q gr/, 6 f,2.7hc=-,cl,!cL-ic Propertiss of Cd-6b AUoyog byV. A. Yhrkov, X. 1. Alskseywmp 2 pp.RMIAN, per, Zbur Takh I= nso Val Ml; No 4,,Apr 1956,, pp 9U-912.Awr Ust, of PhysSoviet no-"cbftl I so 4~742 9154-A - "IceAug 57The lborav*loozris PropwtUt a tM AllMmft-Cd &M ft.C4# by V. Am Yaxkmp T. V. Iskmam.,4 pp.mnums per# m NVUL I Noun"# VOL Tma, so 1j,IMP pp al-ehopp5"oat 6c / 3 0', /t~~To la; | 1983 | 2026-04-02T13:08:43Z |
| Ep 10 Part 2: Kristine Bunch's Struggle For Freedom | In Part 2 of this episode, Kristine and her newly-formed defense team fight to win back her freedom. Armed with advances in fire science, a potential Brady violation, and some shocking revelations about the State's evidence at trial, Kristine and her team fight till the very end. A special thank you to Kristine Bunch for helping me tell her story. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie. Music featured in this episode: Like Music (cdk Mix) by cdk (c) copyright 2015 Licensed under a Creative Commons Attribution Share-Alike (3.0) license. http://dig.ccmixter.org/files/cdk/48915 Ft: Phasenwandler Homesick (Keymix) by keytronic (c) copyright 2014 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/Keytronic/47457 Ft: Kizzylotus Paper Planes - Durd; | 2016 | 2023-07-08T12:43:12Z |
| ginerbreadman | ginerbreadman | | 2022-11-15T19:45:05Z |
| EP 12: Kelsey Smith - Abducted In Broad Daylight | Kelsey Smith was just 18 years old when she was abducted from a Target parking lot in Overland Park, Kansas in June 2007. Finding her would take a battle with a cellular phone company and heartbreaking surveillance video from Target, that shows that no one is ever really safe, even if you're running a simple errand in broad daylight. A special thank you to Kelsey's mom, Missey Smith, for speaking with me for this episode. To learn more about the Kelsey Smith Foundation and the Kelsey Smith Act, please visit kelseysarmy.org. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode: - Summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/cdk/13112 - Like Music (cdk Mix) by c; | 2017 | 2023-07-08T12:40:23Z |
| AutoDesk Cyberspace Developer Kit v1.0.1 | From the README: Notes on the Autodesk Cyberspace Developer Kit 1.0.1 ==================================================== INCOMPATIBILITIES ----------------- IMPORTANT: This release, CDK 1.0.1, is incompatible with release 1.0 in several areas, including displays, solids, and DSCVR. To use this new release, it is necessary to recompile any of your code that refers to CDK header files. HIGHLIGHTS OF THIS RELEASE -------------------------- This is an update of CDK Release 1.0. Some bugs have been fixed (most notably in the SPEAdisp and VESAdisp display classes), and some features added (particularly in the CDF reader). Also, this release supports the MetaWare C++ compiler release 3.1, the Phar Lap DOS Extender release 5.1, and the FTP Software release 2.2, in addition to previously supported releases of these products. The Zortech C++ compiler release 3.0 is supported as well. This README.TXT document also contains a complete summary of environment variable settings needed for c; | 1993 | 2022-05-13T07:50:27Z |
| 【小迪安全】红蓝对抗 ｜ 网络攻防 ｜ V2023全栈培训-上 | Original URL：https://www.bilibili.com/video/BV12om2YTEgW/ 1. 第1天：基础入门-Web应用&架构搭建&站库分离&路由访问&配置受限&DNS解析 (1:32:47) 2. 第2天：基础入门-Web架构&前后端分离站&Docker容器站&集成软件站&建站分配 (1:39:51) 3. 第3天：基础入门-Web架构&OSS存储&负载均衡&CDN加速&反向代理&WAF防护 (1:28:15) 4. 第4天：基础入门-APP架构&小程序&H5+Vue语言&Web封装&原生开发&Flutter (1:15:44) 5. 第5天：基础入门-反弹SHELL&不回显带外&正反向连接&防火墙出入站&文件下载 (1:44:15) 6. 第6天：基础入门-抓包技术&HTTPS协议&APP&小程序&PC应用&WEB&转发联动 (1:46:25) 7. 第7天：基础入门-抓包技术&全局协议&封包监听&网卡模式&APP&小程序&PC应用 (1:16:53) 8. 第8天：基础入门-算法分析&传输加密&数据格式&密文存储&代码混淆&逆向保护 (1:35:30) 9. 第9天：基础入门-算法逆向&散列对称非对称&JS源码逆向&AES&DE; | 2024 | 2026-06-23T06:15:43Z |
| Het Utrechts Archief 168793 | Het Utrechts Archief catalog number: 168793 Description (Dutch): Afbeelding van een gezelschap op het 4e perron van het N.S.-station Rotterdam C.S. te Rotterdam, bij het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het betreft hier een gezelschap uit een extra trein voor de Handelsmaatschappij R.S. Stokvis en Zonen. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610). | 1961 | 2021-02-03T11:11:51Z |
| My Top Cases of 2016 | We all have cases that we follow and that stick with us, whether it's on a personal level or because we're oddly fascinated with them. In this episode, I count down the top cases that affected me the most this year. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode: - Improvisation On Friday... by Alex (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/AlexBeroza/17253 Ft: The3amAssociation - CAliformia Road by dilating_times (c) copyright 2014 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/dilating_times/44880 - summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/cdk/13; | 2016 | 2023-07-08T12:41:41Z |
| CIA Reading Room cia-rdp80b01676r002800250020-5: LETTER TO HONORABLE JOEL T. BROYHILL FROM LIEUTENANT GENERAL MARSHALL S. CARTER | Approved For Release 2003/11/04: CIA-RDP80B01676R002800250020-5 E.::c. a .. y . C. O"r w- *401u, E=7-7~ .r u yu It bw bum son t L IVV14md And w" I- I Distribution; 0&1-Adressee 1 -DCI 1-D RR w/basic rag. CO.... a;. 1 ` Sub ect?s tils f/e3.d is CkVQw R Approved For l4lease 2003/1/04: CIA-RDP80B01676R002800250020-5 STAT 'JOT 5 Approved For Release 2003/11/04: CIA-RDP80B01676R002800250020-5 APR 1962 STAT STAT DiathbuiAcn: 0 - AMdresaes l~ Rep. STAT 1-DCI 1?~ . -Sub t,' v car basic OD/.Peru/[:=Pr (16 Apr 62) Approved For Release 2003/11/04: CIA-RDP80BO1676R002800250020-5 STAT -. JOEL T. BROYHILLApproved For Release 2003/11/04: CIA-RDP80B01676R00280025002 ,MITTEES: i OTH DISTRICT, VIRGINIA POST OFFICE AND CIVIL SERVICE ? DISTRICT OF COLUMBIA CITIES: COUNTIES: ALEXANDRIA ARLINGTON FAIRFAX CITY FAIRFAX FALLS CHURCH (tongreo of the Nniteb 'tateo 3ouze of 3epresentatibeg 40bington, D. C. April 11, 1962 The Honorable John A. McCone Director, Central Intelligence Agency Washington 25, D.C. HOMER ; | 1962 | 2024-01-16T09:53:19Z |
| Cyclin K goes with Cdk12 and Cdk13. | This article is from Cell Division , volume 7 . Abstract The cyclin-dependent kinases (Cdks) regulate many cellular processes, including the cell cycle, neuronal development, transcription, and posttranscriptional processing. To perform their functions, Cdks bind to specific cyclin subunits to form a functional and active cyclin/Cdk complex. This review is focused on Cyclin K, which was originally considered an alternative subunit of Cdk9, and on its newly identified partners, Cdk12 and Cdk13. We briefly summarize research devoted to each of these proteins. We also discuss the proteins' functions in the regulation of gene expression via the phosphorylation of serine 2 in the C-terminal domain of RNA polymerase II, contributions to the maintenance of genome stability, and roles in the onset of human disease and embryo development. | 2012 | 2014-10-27T22:08:10Z |
| Identification of Genes Interacting with rnt-1 Through Large-Scale RNAi Screening in Caenorhabditis elegans. | This article is from G3: Genes|Genomes|Genetics , volume 3 . Abstract Although many critical roles of the RUNX family proteins have already been identified, little attention has been given to how these proteins interact with other factors. Elucidating RUNX protein interactions will help extend our understanding of their roles in normal development and tumorigenesis. In this study, we performed large-scale RNAi screening to identify genes that genetically interact with rnt-1, the sole homolog of RUNX protein in the nematode Caenorhabditis elegans. To this end, we took advantage of the fact that C. elegans can survive a severe loss of RNT-1 function with only mild phenotypes, and we looked for genes that caused a synthetic phenotype in the rnt-1 mutant background. We identified seven genes, three of which (cdk-8, cic-1, and sur-2) are involved in transcription, two of which (pgp-2 and cct-5) are involved in stress response, and two of which (D2045.7 and W09D10.4) are involved in signalin; | 2013 | 2014-10-28T00:42:20Z |
| github.com-localstack-localstack_-_2021-11-19_13-25-02 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline! LocalStack provides an easy-to-use test/mocking framework for developing Cloud applications. Overview • Install • Run • Configure • Play – 📖 Docs • 💻 Pro version • ☑️ Feature coverage • 📢 Announcements Overview LocalStack 💻 is a cloud service emulator that runs in a single container on your laptop or in your CI environment.With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider!Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services,LocalStack helps speed up and simplify your testing and development workflow. LocalStack supports a growing number of AWS services, like AWS Lambda, S3, Dynamodb, Kinesis, SQS, SNS, and many more!The Pro version of LocalStack supports additional APIs and advanced features.You c; | 2021 | 2021-11-19T14:17:34Z |
| github.com-localstack-localstack_-_2023-09-30_18-12-34 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline :zap: Join the LocalStack Insiders program to help us shape the future of LocalStack! Test drive new features & engage in conversations with us so we can learn from your use cases :zap: LocalStack provides an easy-to-use test/mocking framework for developing cloud applications. Overview • Install • Example • Run • Usage • Releases • Contributing 📖 Docs • 💻 Pro version • ☑️ LocalStack coverage Overview LocalStack is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack s; | 2023 | 2023-10-01T06:18:17Z |
| CIA Reading Room cia-rdp90-00552r000100550040-8: PANEL FINDS CASEY NOT UNFIT FOR JOB | Sanitized Copy Approved for Release 2010/07/29: CIA-RDP90-00552R000100550040-8 NEW YORK TIES E, i' i CLE AIPPEA D 2 DECEMBER 1981 C )IN, PAGE' PANEL ~ , "mg a~ ~t~t tbar~rt the public at saon WadDeKI&Y. r. Noyaiban MW the delay wos.d ernmit ? flies UNFIT I$ the m ;" r of tld c xx* atte,e?a 13 members .rno crula not attend today's s tasks aboutbair v3ee-s on the pane 's eaneiusiom, erxd we+ald Per=ft; Mr. Caaay tozs+3ew them, But 'Whole. Situation is Not rroE,a Moynihan mW uttering,' Senator Sa M. a tthhet: ?o"'di of intelligence Director$ ~- ,to on o`r 1he added ;w 1e ji vse,.a, a sms~ ' used to ref 4Z931JAl3331R33i~ grtoi Josepb R BiBea Jr., Demoemt of Deiawere, said in an WASB1NGTa f,13ee. I -The Se stet iota view aZter the m eetin, that be disa.. Select C ommit ee en bMH*mm will geed with the etanmittee's ~? that and has no ham roe William J. Cawy is "mat to aeey-e as m 0'1 bare a very dirfermt V3tw iron rectorof Caatr*i;atailia,estca,seco~rdins that of nay cdk~e es m the ~iZer,'? t; | 1981 | 2025-06-03T23:01:26Z |
| CIA Reading Room cia-rdp91-00929r000200680025-9: FR:SHUBKIN V.N. TO:SHULISHOVA O.I. | - 14 , /.el iconelvto stuat at seem lw V. ov*WAD ,15 P9owns Pori, 1b 3# FM 65# IV WOW$I" 2Z3.1ummemApr 65 7no ?rlIbmis ft no& 206or a* zatw yorms lw To so /0Mdu%,%Tw~m vwo so= tumob ft so ow^ wo WIGNo st3ps~ kl,~oV, ~- -, k L)--um9mAn 6520630quanutatAve Nrtboft la ftWWUWt by Yo So17 vp o--- - vwp &g= UMMW 1b- 3~ X967ioIV? 0JIPMB "3~t. IV SHU6KIAl.2 cumbd4kc ftlime 67 329pM'4-4 7'r-QV'4rtl*S Of DWGIVUlt 4'AtlrAinS Of tl%w 45Vino of vie (.4cm tior~4s (,,orivo siqlax),UY %* F~, Ct 419'it ~*T, v--~Virux %lo it IL66v 17-p 74-76.i. ~~41 ~ ~''Cim"Alrvu f, I 3tiows0~. ( J /' (~. 6 ' ~ /' t"The so-called Homology of Crystals,, by A. V. ShubnikovRUSSIAN, per, Doklady Akadewit Nauk SSSR Vol 88,pp 453-456NAVY/NISC-3346Oct 72Growth ct C4ft*IkUt tV A. V. MuUdkNp V, X.abdull0 -U:WROM ppmo "a cc VWM&A& !=Wamom-Nms To, AW f,~ 4 -, . I r -- , (tic!AVv 4,i*l 1 ~ -swo4w Ge dbs ftugk as"d via llsbr5-1 eusumbohm-Aodk*V&t v IV 91 At 99 pw* It 901 "s 19496or 209-43"-ftota isterimKrArrA-324brek 1970-ft 33Oft L; | 1983 | 2026-04-05T21:18:00Z |
| CIA Reading Room cia-rdp83m00914r002900060005-4: I AM PLEASED TO INVITE YOU TO A ONE-DAY SPECIAL SECURITY PRESENTATION | Approved For Release 2006/0 Y2rY A`TR _ 83M00914R002900060005-4 Washington. D. C 20505 31 MAR 1982 ER 82-4708/1 I am pleased to invite you to a one-day-special security pres- entation sponsored by the White House and hosted by the Central Intelligence Agency at n Thursday, 25X1 13 May 1982. This session w i l l give those o you who were unable to attend last year the chance to do so. The schedule is enclosed. This highly-selective session has been designed to meet your special needs as an official Government spokes- person. I promise you it will be interesting and informative. The day is intended to broaden your knowledge and enhance your effective- ness throughout your period of Government service. If my schedule holds, I plan to be with you for at least a portion of the day. Kindly direct your response to CIA's Public Affairs office, telephone 351-7676. I hope to see you there. Sincerely, I g ail William J. Casey Director of Central Intelligence Enclosure UNCLASSIFIED WHEN SEPARATED ; | 1982 | 2024-07-15T20:22:12Z |
| Plant WEE1 kinase is cell cycle regulated and removed at mitosis via the 26S proteasome machinery. | This article is from Journal of Experimental Botany , volume 64 . Abstract In yeasts and animals, premature entry into mitosis is prevented by the inhibitory phosphorylation of cyclin-dependent kinase (CDK) by WEE1 kinase, and, at mitosis, WEE1 protein is removed through the action of the 26S proteasome. Although in higher plants WEE1 function has been confirmed in the DNA replication checkpoint, Arabidopsis wee1 insertion mutants grow normally, and a role for the protein in the G2/M transition during an unperturbed plant cell cycle is yet to be confirmed. Here data are presented showing that the inhibitory effect of WEE1 on CDK activity in tobacco BY-2 cell cultures is cell cycle regulated independently of the DNA replication checkpoint: it is high during S-phase but drops as cells traverse G2 and enter mitosis. To investigate this mechanism further, a yeast two-hybrid screen was undertaken to identify proteins interacting with Arabidopsis WEE1. Three F-box proteins and a subunit of t; | 2013 | 2014-10-23T22:24:00Z |
| github.com-serverless-stack-serverless-stack_-_2022-02-07_09-07-40 | 💥 SST makes it easy to build serverless apps. Set breakpoints and test your functions locally. https://serverless-stack.com Serverless Stack (SST) is a framework that makes it easy to build serverless apps. It's an extension of AWS CDK and it features: A Live Lambda Development environment Support for setting breakpoints and debugging in VS Code Support for deploying to multiple environments and regions Higher-level constructs designed specifically for serverless apps Zero-config support for JS and TS (using esbuild ), Go, Python, C#, and F# Quick Start Create your first SST app. ```bash Create your app $ npx create-serverless-stack@latest my-sst-app$ cd my-sst-app Start Live Lambda Development $ npx sst start Deploy to prod $ npx sst deploy --stage prod``` Documentation SST docs SST examples Public roadmap Feature requests Contributing to SST Follow us on Twitter and subscribe to our newsletter for updates. About SST We think SST can make it dramatically easier to build serverless ; | 2022 | 2022-02-07T09:45:28Z |
| github.com-sottlmarek-DevSecOps_-_2022-01-14_09-42-59 | Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevSecOps scope. Table of Contents Def; | 2022 | 2022-01-14T21:43:52Z |
| Teaching and Learning Adolescent Psychiatry | | 1971 | 2025-09-26T19:28:34Z |
| Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks. | This article is from BMC Systems Biology , volume 6 . Abstract Background: High-throughput measurement technologies produce data sets that have the potential to elucidate the biological impact of disease, drug treatment, and environmental agents on humans. The scientific community faces an ongoing challenge in the analysis of these rich data sources to more accurately characterize biological processes that have been perturbed at the mechanistic level. Here, a new approach is built on previous methodologies in which high-throughput data was interpreted using prior biological knowledge of cause and effect relationships. These relationships are structured into network models that describe specific biological processes, such as inflammatory signaling or cell cycle progression. This enables quantitative assessment of network perturbation in response to a given stimulus. Results: Four complementary methods were devised to quantify treatment-induced activity changes in processes described by ; | 2012 | 2014-10-25T01:34:45Z |
| github.com-DovAmir-awesome-design-patterns_-_2022-12-08_10-37-12 | A curated list of software and architecture related design patterns. Awesome Software and Architectural Design Patterns A curated list of software and architecture related design patterns. Software design pattern - A general, reusable solution to a commonly occurring problem within a given context in software design. It is a description or template for how to solve a problem that can be used in many different situations. Contents Programming language design patterns General Architecture Cloud Architecture Serverless Architecture Micro services & Distributed Systems Internet of things Big Data Databases and storage DevOps & containers Mobile Front End Development Security Programming Language Design Patterns AngularJS design patterns C# design-patterns design-patterns-for-human - ultra simplified explanation to design patterns. Design Patterns Library C++ design-patterns Closure design-patterns Go design-patterns Java sourcemaking - patterns and anti patterns. oodesign - patterns catalo; | 2022 | 2022-12-15T12:47:03Z |
| Inhibition of Post-Transcriptional RNA Processing by CDK Inhibitors and Its Implication in Anti-Viral Therapy. | This article is from PLoS ONE , volume 9 . Abstract Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle and RNA polymerase II mediated transcription. Several pharmacological CDK inhibitors are currently in clinical trials as potential cancer therapeutics and some of them also exhibit antiviral effects. Olomoucine II and roscovitine, purine-based inhibitors of CDKs, were described as effective antiviral agents that inhibit replication of a broad range of wild type human viruses. Olomoucine II and roscovitine show high selectivity for CDK7 and CDK9, with important functions in the regulation of RNA polymerase II transcription. RNA polymerase II is necessary for viral transcription and following replication in cells. We analyzed the effect of inhibition of CDKs by olomoucine II on gene expression from viral promoters and compared its effect to widely-used roscovitine. We found that both roscovitine and olomoucine II blocked the phosphorylation of RNA polymerase II C-termi; | 2014 | 2014-10-23T20:50:01Z |
| PD-0332991 induces G1 arrest of colorectal carcinoma cells through inhibition of the cyclin-dependent kinase-6 and retinoblastoma protein axis. | This article is from Oncology Letters , volume 7 . Abstract Preclinical and clinical studies have demonstrated the anticancer activity of PD-0332991, a selective cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, in the treatment of various types of cancer in a retinoblastoma protein (RB)-dependent manner. However, it remains unclear whether CDK4, CDK6 or both are required for RB phosphorylation in colorectal carcinoma and thus PD-0332991 can be used to target this CDK-RB axis for the cancer therapy. The aim of this study was to determine whether CDK4, CDK6 and phosphorylated RB proteins were overexpressed in colorectal carcinoma tissues as compared to matched normal colorectal tissues. The results showed that knockdown of CDK6 but not CDK4 reduced RB phosphorylation and inhibited carcinoma cell growth. Thus, CDK6 plays a critical role in RB phosphorylation and cancer growth. PD-0332991 treatment blocked RB phosphorylation and inhibited cell growth through the induction of G1 arrest of co; | 2014 | 2014-10-23T06:07:14Z |
| Protein kinase C signaling and cell cycle regulation. | This article is from Frontiers in Immunology , volume 3 . Abstract A link between T cell proliferation and the protein kinase C (PKC) family of serine/threonine kinases has been recognized for about 30 years. However, despite the wealth of information on PKC-mediated control of, T cell activation, understanding of the effects of PKCs on the cell cycle machinery in this cell type remains limited. Studies in other systems have revealed important cell cycle-specific effects of PKC signaling that can either positively or negatively impact proliferation. The outcome of PKC activation is highly context-dependent, with the precise cell cycle target(s) and overall effects determined by the specific isozyme involved, the timing of PKC activation, the cell type, and the signaling environment. Although PKCs can regulate all stages of the cell cycle, they appear to predominantly affect G0/G1 and G2. PKCs can modulate multiple cell cycle regulatory molecules, including cyclins, cyclin-dependent kin; | 2013 | 2014-10-28T20:08:08Z |
| Predict shipment ETA with no-code machine learning using Amazon SageMaker Canvas | Over the last few years, online education platforms have seen an increase in adoption of and an uptick in demand for video-based learnings because it offers an effective medium to engage learners. To expand to international markets and address a culturally and linguistically diverse population, businesses are also looking at diversifying their learning offerings by localizing content into multiple languages. These businesses are looking for reliable and cost-effective ways to solve their localization use cases. Localizing content mainly includes translating original voices into new languages and adding visual aids such as subtitles. Traditionally, this process is cost-prohibitive, manual, and takes a lot of time, including working with localization specialists. With the power of AWS machine learning (ML) services such as Amazon Transcribe , Amazon Translate , and Amazon Polly , you can create a viable and a cost-effective localization solution. You can use Amazon Transcribe to create a; | 2022 | 2022-08-10T05:07:03Z |
| Street Fighter Alpha 2 (960430 USA): (BO) Charli1 vs(BR) [CDK]-Shaka - 2022-08-22 01:50:02 | (BO) Charli1 (Rank B) vs (BR) [CDK]-Shaka C - 2022-08-22 01:50:02 Fightcade replay id: 1661133002235-2363 0:00 Charlie vs Ryu 02:06 Charlie vs Guy #fightcade #sfa2u #Charli1 #Ryu #[CDK]-Shaka #0:00:12 #Guy #0:02:06 For more videos check out: https://fightcadevids.com | | 2023-01-23T15:42:07Z |
| github.com-localstack-localstack_-_2023-09-29_02-11-07 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline :zap: Join the LocalStack Insiders program to help us shape the future of LocalStack! Test drive new features & engage in conversations with us so we can learn from your use cases :zap: LocalStack provides an easy-to-use test/mocking framework for developing cloud applications. Overview • Install • Example • Run • Usage • Releases • Contributing 📖 Docs • 💻 Pro version • ☑️ LocalStack coverage Overview LocalStack is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack s; | 2023 | 2023-09-29T05:13:28Z |