| Author | Title | Print-Published | Type | DOI@Sci-hub |
| CDK | | reference-entry | 10.1007/springerreference_92996 |
| Functions of CDK/cyclin Complexes in Endoreplication Regulation by the CDK Inhibitor SIAMESE | | dissertation | 10.31390/gradschool_dissertations.5173 |
| CDK | | reference-entry | 10.1007/springerreference_37256 |
| Pandit, J. | Novel CDK-5 inhibitors - crystal structure of inhibitor EFQ with CDK-2 | 2009/9/8 | dataset | 10.2210/pdb3igg/pdb |
| Pandit, J. | Novel CDK-5 inhibitors - crystal structure of inhibitor EFP with CDK-2 | 2009/9/8 | dataset | 10.2210/pdb3ig7/pdb |
| Figure 4—figure supplement 1. CDK–phosphorylation of ORC intrinsically inhibits helicase loading. | | component | 10.7554/elife.33309.013 |
| CDK Inhibitor R547 | | reference-entry | 10.32388/iap5sl |
| Willighagen, Egon | 10000 CDK commits! | | posted-content | 10.59350/w1hpp-ks316 |
| Willighagen, Egon | CDK Literature #3 | | posted-content | 10.59350/rkkty-a3w29 |
| Willighagen, Egon | CDK News | | posted-content | 10.59350/xf9bq-44218 |
| Willighagen, Egon | CDK Literature #4 | | posted-content | 10.59350/es4e7-esh15 |
| Cermin Dunia Kedokteran | | journal | 10.55175/cdk |
| CDK | | book-chapter | 10.1007/3-540-30683-8_274 |
| CDK Inhibitor AT7519 | | reference-entry | 10.32388/286jz0 |
| CDK Gene Mutation | | reference-entry | 10.32388/kf9klo |
| Willighagen, Egon | CDK Literature #1 | | posted-content | 10.59350/g22fv-gtc07 |
| Willighagen, Egon | StatCVS on CDK | | posted-content | 10.59350/q7ehm-v1m81 |
| Hu, X. | Cdc2: a monopotent or pluripotent CDK? | 2011/6 | journal-article | 10.1111/j.1365-2184.2011.00753.x |
| Willighagen, Egon | CDK Literature #2 | | posted-content | 10.59350/17nhx-htt54 |
| CDK | | book-chapter | 10.1007/978-3-540-47648-1_959 |
| Supplementary file 1. CDK sequences used for phylogenetic analysis | | component | 10.7554/elife.10767.021 |
| Huang, Linda | Faculty Opinions recommendation of Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. | 2007/4/23 | dataset | 10.3410/f.1080804.533727 |
| Apodaca, Richard L. | Updating Ruby CDK | | posted-content | 10.59350/yy9a2-wy148 |
| Willighagen, Egon | Nightly CDK builds now available | | posted-content | 10.59350/s63wt-hbx56 |
| CDK Inhibitor SNS-032 | | reference-entry | 10.32388/2sggcz |
| Willighagen, Egon | The CDK data model #1 | | posted-content | 10.59350/4xfms-7nn46 |
| Willighagen, Egon | CDK-Taverna fully recognized | | posted-content | 10.59350/pk40z-7z702 |
| Schreiner, S. | Kongenitale Kniegelenkluxation (CDK) | 2012/1 | journal-article | 10.1007/s00132-011-1874-7 |
| cdk | | book-chapter | 10.1007/3-540-29832-0_321 |
| CDK | | book-chapter | 10.1007/978-3-540-38918-7_5357 |
| Willighagen, Egon | CDK Module dependencies #2 | | posted-content | 10.59350/e7qrk-ypg78 |
| cdk | | book-chapter | 10.1007/3-540-29719-0_321 |
| Willighagen, Egon | CDK Workshop - Day #2 | | posted-content | 10.59350/f7vn0-kqz26 |
| Carnero, A. | The INK4 Family of CDK Inhibitors | 1998 | book-chapter | 10.1007/978-3-642-71941-7_3 |
| CDK Inhibitors | | book-chapter | 10.1007/978-3-540-47648-1_963 |
| | | journal-issue | 10.55175/cdk.v48i6 |
| Valk, Ervin | CDK signaling via nonconventional CDK phosphorylation sites | 2023/11/1 | journal-article | 10.1091/mbc.e22-06-0196 |
| Grigoroudis, Asterios I. | Preparation of CDK/Cyclin Inhibitor Complexes for Structural Determination | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_4 |
| Apodaca, Richard L. | Ruby CDK for Newbies | | posted-content | 10.59350/50ebs-4zq55 |
| Willighagen, Egon | Atom typing in the CDK | | posted-content | 10.59350/wm7aq-eqz10 |
| Willighagen, Egon | Single PDFs for CDK News articles | | posted-content | 10.59350/rgdzb-bfe36 |
| Alvira, Daniel | Drug Delivery Strategies of Chemical CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_12 |
| Hu, Shanhu | Targeting anaphase catastrophe through CDK inhibition in lung cancer | | dissertation | 10.1349/ddlp.1623 |
| Degradation by Design: New Cyclin K Degraders from Old CDK Inhibitors | | component | 10.1021/acschembio.3c00616.s002 |
| | | journal-issue | 10.55175/cdk.v47i7 |
| Willighagen, Egon | Java Server Pages with CDK functionality | | posted-content | 10.59350/3kvks-pdb73 |
| CDK Inhibitory Protein | | book-chapter | 10.1007/3-540-30683-8_276 |
| Willighagen, Egon | Calculating geometrical properties with the CDK | | posted-content | 10.59350/sy6r5-pzw09 |
| CDK Inhibitors | 2011 | book-chapter | 10.1007/978-3-642-16483-5_963 |
| Apodaca, Richard L. | CDK, the Ruby Way | | posted-content | 10.59350/49w1p-2y164 |
| Willighagen, Egon | Jumbo 5.0 and the CDK | | posted-content | 10.59350/y0mte-4ns18 |
| Willighagen, Egon | CDK close to entering Debian | | posted-content | 10.59350/dmspa-wyb25 |
| | | journal-issue | 10.55175/cdk.v48i2 |
| CDK | 2011 | book-chapter | 10.1007/978-3-642-16483-5_959 |
| Gortat, Anna | Analysis of CDK Inhibitor Action on Mitochondria-Mediated Apoptosis | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_9 |
| | | journal-issue | 10.55175/cdk.v47i11 |
| CDK/JAK2/FLT3 Inhibitor TG02 Citrate | | reference-entry | 10.32388/xklmgh |
| CDK | 2016 | book-chapter | 10.1007/978-3-662-46875-3_100468 |
| | | journal-issue | 10.55175/cdk.v49i0 |
| Apodaca, Richard L. | Scripting CDK with JRuby | | posted-content | 10.59350/sxxfq-shj88 |
| Willighagen, Egon | The CDK data classes and change notifications | | posted-content | 10.59350/3xsm0-bt478 |
| Willighagen, Egon | CDK Workshop - Days #3 and #4 | | posted-content | 10.59350/kvq10-snm07 |
| CDK-Activating Kinase Assembly Factor MAT1 | | reference-entry | 10.32388/6s4tbs |
| Willighagen, Egon | CDK Bug Squash Party - Day 5 | | posted-content | 10.59350/paxbm-rac78 |
| Willighagen, Egon | CDK Bug Squash Party - Day 2 | | posted-content | 10.59350/wzs4m-9ky43 |
| Willighagen, Egon | The CDK/Metabolomics/Chemometrics Unconference results | | posted-content | 10.59350/f2ajz-tmr63 |
| Willighagen, Egon | CDK and the Java 6 beta | | posted-content | 10.59350/6az21-1dt76 |
| Willighagen, Egon | Jumbo 5.0 and CML support in CDK | | posted-content | 10.59350/dzvnw-3b413 |
| Apodaca, Richard L. | Porting MX - CDK-Compatible VF Implementation | | posted-content | 10.59350/xat1r-hcs92 |
| | | journal-issue | 10.55175/cdk.v48i4 |
| Hirai, Hiroshi | Evaluating Chemical CDK Inhibitors as Cell Death Inducers | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_14 |
| | | journal-issue | 10.55175/cdk.v47i10 |
| Willighagen, Egon | CDK Bug Squash Party - Day 1 | | posted-content | 10.59350/y5srm-hzx87 |
| Lacy, Susan | Identification of a p130 domain mediating interactions with cyclin A/cdk 2 and cyclin E/cdk 2 complexes | 1997/5/22 | journal-article | 10.1038/sj.onc.1201085 |
| | | journal-issue | 10.55175/cdk.v47i8 |
| | | journal-issue | 10.55175/cdk.v47i12 |
| Upton, Jason W. | Evidence for CDK-Dependent and CDK-Independent Functions of the Murine Gammaherpesvirus 68 v-Cyclin | 2006/12/15 | journal-article | 10.1128/jvi.01722-06 |
| Willighagen, Egon | UML diagram of CDK module dependencies | | posted-content | 10.59350/a3r1n-72841 |
| Apodaca, Richard L. | Scripting Molecular Fingerprints with Ruby CDK | | posted-content | 10.59350/xgf37-ggz21 |
| | | journal-issue | 10.55175/cdk.v47i9 |
| | | journal-issue | 10.55175/cdk.v48i5 |
| | | grant | 10.55776/tai3266225 |
| | | journal-issue | 10.55175/cdk.v48i1 |
| | | journal-issue | 10.55175/cdk.v48i3 |
| | | journal-issue | 10.55175/cdk.v42i10 |
| Degradation by Design: New Cyclin K Degraders from Old CDK Inhibitors | | component | 10.1021/acschembio.3c00616.s001 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 1999/8/1 | report | 10.21236/ada378108 |
| Guevara, Tatiana | Evaluating the Effects of CDK Inhibitors in Ischemia–Reperfusion Injury Models | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_10 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s002 |
| Ruiz, E. Josué | Meiotic Inactivation of Xenopus Myt1 by CDK/XRINGO, but Not CDK/Cyclin, via Site-Specific Phosphorylation | 2008/10 | journal-article | 10.1016/j.molcel.2008.08.029 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s003 |
| Lee, Young-Sam | Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates | 2007/4/6 | journal-article | 10.1126/science.1139080 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 2000/9/1 | report | 10.21236/ada392485 |
| Apodaca, Richard L. | CDK, the Ruby Way: RCDK-0.2.0 | | posted-content | 10.59350/ev966-zz940 |
| Guha, Rajarshi | rcdk: Interface to the 'CDK' Libraries | 2006/10/4 | dataset | 10.32614/cran.package.rcdk |
| GROTH, A | High-density growth arrest in Ras-transformed cells: low Cdk kinase activities in spite of absence of p27 Cdk-complexes | 2005/9 | journal-article | 10.1016/j.cellsig.2004.11.021 |
| Gallastegui, Edurne | Immunoprecipitation of Cdk–Cyclin Complexes for Determination of Kinase Activity | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_1 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s001 |
| Apodaca, Richard L. | Drawing 2-D Structures with Structure-CDK | | posted-content | 10.59350/qxc8d-c1w35 |
| Cyclin-dependent Kinase (CDK) Inhibitor | | book-chapter | 10.1007/3-540-30683-8_390 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s004 |
| Fisher, Robert P | Faculty Opinions recommendation of Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation. | 2008/11/11 | dataset | 10.3410/f.1125916.583024 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 1998/8/1 | report | 10.21236/ada359281 |
| Gangopadhyay, Aditi | The Prospects of CDK Targeting and Clinical Application of CDK Inhibitors in Cancer | 2018/12/5 | book-chapter | 10.2174/9781681087016118090008 |
| Willighagen, Egon | CDK 1.0: a milestone after 7 year of development | | posted-content | 10.59350/qd21w-71g30 |
| Willighagen, Egon | The molecular QSAR descriptors in the CDK | | posted-content | 10.59350/47rre-wwc20 |
| lavarone, Antonio | Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15 | 1997/5 | journal-article | 10.1038/387417a0 |
| Chiarelli, C | Cyclin D, CDK and CDK Inhibitors in Melanocytic Neoplasms. | 1997/8 | journal-article | 10.1097/00000372-199708000-00072 |
| Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk) | | component | 10.1021/acschembio.7b00972.s002 |
| Willighagen, Egon | Test results for the CDK 1.0.x branch | | posted-content | 10.59350/ry980-qya21 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v49i2.1746 |
| Willighagen, Egon | InChI's in LaTex and CDK News | | posted-content | 10.59350/hysd0-wvc09 |
| Synthesis of benzofuropyridine derivatives as CDK-5 inhibitors and anticancer agents | | dissertation | 10.58837/chula.the.2022.1218 |
| CDK | | other | 10.1002/0471684228.egp01945 |
| Guha, Rajarshi | rcdklibs: The CDK Libraries Packaged for R | 2009/1/8 | dataset | 10.32614/cran.package.rcdklibs |
| Pérez-Benavente, Beatriz | Cell Synchronization Techniques to Study the Action of CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_8 |
| Willighagen, Egon | CDK Debug classes and fixing the ModelBuilder3D bug | | posted-content | 10.59350/6p49t-sj396 |
| Willighagen, Egon | CDK News 2.3 and InChI's | | posted-content | 10.59350/z97vw-87009 |
| Multiplexed Profiling of CDK Kinase Activities in Tumor Biopsies with Fluorescent Peptide Biosensors | | component | 10.1021/acssensors.4c00139.s001 |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v48i12.1586 |
| Willighagen, Egon | CDK Bug Squash Party - Day 3 and 4 | | posted-content | 10.59350/zwkym-aty79 |
| Figure 3: The efficiency of tumor markers in distinguish CDK patients from healthy control. | | component | 10.7717/peerj.19240/fig-3 |
| | | grant | 10.55776/t393 |
| Palomino-Schätzlein, Martina | Metabolomic Applications to the Characterization of the Mode-of-Action of CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_16 |
| Willighagen, Egon | R/CDK install fails on GCC 4.0 systems | | posted-content | 10.59350/b1vyj-0kd63 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v48i12.1589 |
| CDK | 2008 | book-chapter | 10.1007/978-1-4020-6754-9_2580 |
| Many Hats for Cdk Inhibitor | 2006/1/10 | journal-article | 10.1126/stke.3172006tw468 |
| Futcher, A. B. | General Methods for Identifying G1-phase Substrates of Cdk Protein Kinases | 1999/6/1 | report | 10.21236/ada374137 |
| | | grant | 10.35802/065956 |
| Willighagen, Egon | CDK is now available from your nearest Debian mirror | | posted-content | 10.59350/g5s78-zqk90 |
| Guidato, Sonia | Cyclin D2 Interacts with cdk‐5 and Modulates Cellular cdk‐5/p35 Activity | 1998/1 | journal-article | 10.1046/j.1471-4159.1998.70010335.x |
| Tsutsui, Taiki | Identification of target genes for the CDK subunits of the Mediator complex | 2011/12 | journal-article | 10.1111/j.1365-2443.2011.01565.x |
| -, - | Indeks Akhir Tahun | | journal-article | 10.55175/cdk.v48i12.1588 |
| CDK Inhibitors, Endocrine Therapy for Male Patients With Breast Cancer | 2019/3/8 | dataset | 10.1200/adn.19.190134 |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v49i2.1745 |
| Willighagen, Egon | Janocchio: Jmol and CDK based 1H coupling constant prediction | | posted-content | 10.59350/rxzh8-9yr48 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v49i1.1648 |
| Nishizawa, Masafumi | Mouse Cyclin-dependent Kinase (Cdk) 5 Is a Functional Homologue of a Yeast Cdk, Pho85 Kinase | 1999/11 | journal-article | 10.1074/jbc.274.48.33859 |
| Dutto, Ilaria | Assessing Cell Cycle Independent Function of the CDK Inhibitor p21CDKN1A in DNA Repair | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_11 |
| Willighagen, Egon | Protein support in Bioclipse using Jmol and the CDK | | posted-content | 10.59350/23wn4-1nt07 |
| Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk) | | component | 10.1021/acschembio.7b00972.s001 |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v49i1.1647 |
| CELL CYCLE-REGULATION OF THE FANCD2 PROTEIN VIA CDK-MEDIATED S592 PHOSPHORYLATION | | dissertation | 10.23860/thesis-cantres-velez-juan-2020 |
| Apodaca, Richard L. | Source Code Documentation in Ruby: RDoc for Ruby CDK | | posted-content | 10.59350/jf1hb-6ev38 |
| Willighagen, Egon | Comparing JUnit test results between CDK trunk/ and a branch | | posted-content | 10.59350/zs3tv-pp865 |
| Willighagen, Egon | Open Source Java tool chain: CDK compiles and JUnit tests run | | posted-content | 10.59350/933ah-c7f36 |
| Willighagen, Egon | Modern chemistry in the CDK: beyond the two-atom bond | | posted-content | 10.59350/h2ytc-6pt51 |
| Figure 7. Model of how meiotic cells inhibit DNA replication during the MI–MII transition. | | component | 10.7554/elife.33309.026 |
| Apodaca, Richard L. | From IUPAC Name to Molecular Formula with Ruby CDK | | posted-content | 10.59350/1nn38-3ef94 |
| Zettelmeyer, Florian | CDK Digital Marketing: Addressing Channel Conflict with Data Analytics | 2014 | reference-book | 10.4135/9781473969650 |
| Lone, Waseem | Silicon-tethered colchicine aryne cyclo-adduct as a potent molecule for the abrogation of epithelial to mesenchymal transition via modulating cell cycle regulatory CDK-2 and CDK-4 kinases | | posted-content | 10.26434/chemrxiv-2024-rs3lh |
| Shimotohno, Akie | CDKPhosphorylation | | other | 10.1002/9781119312994.apr0336 |
| Apodaca, Richard L. | MX Performance Comparison #3: Substructure Search in MX and CDK | | posted-content | 10.59350/n4y52-t3a30 |
| Willighagen, Egon | Trouble running the CDK JUnit tests with Cacao and Kaffe | | posted-content | 10.59350/rn78z-r7j37 |
| Apodaca, Richard L. | Agile Chemical Informatics Development with CDK and Ruby: RCDK-0.3.0 | | posted-content | 10.59350/c8h7w-n4922 |
| Futcher, A. B. | General Methods for Identifying Gl-phase Substrates of Cdk Protein Kinases. | 1998/6/1 | report | 10.21236/ada366953 |
| Protein kinase (CDK/MAK) | | book-chapter | 10.1007/978-3-540-49756-1_63 |
| Pohl, M. | GWK/CDK-Bank | 1994/1/1 | book-chapter | 10.4337/9781781954218.00152 |
| Prasetya, Damar | Varisela Neonatal | | journal-article | 10.55175/cdk.v47i12.1239 |
| Cyclin-Dependent Kinase (CDK) Inhibitors: StructureActivity Relationships and Insights into the CDK2 Selectivity of 6Substituted 2Arylaminopurines | | component | 10.1021/acs.jmedchem.6b01254.s002 |
| Apodaca, Richard L. | From SMILES to InChI: Rino, CDK, and Ruby Java Bridge | | posted-content | 10.59350/hra9n-qry69 |
| Purnamasari, Maretta Rosabella | Iktiosis Vulgaris | | journal-article | 10.55175/cdk.v47i10.1085 |
| Cyclin-Dependent Kinase (CDK) Inhibitors: StructureActivity Relationships and Insights into the CDK2 Selectivity of 6Substituted 2Arylaminopurines | | component | 10.1021/acs.jmedchem.6b01254.s001 |
| EMPIAR dataset | | | 10.6019/empiar-10438 |
| Shimotohno, Akie | CDK Phosphorylation | | book-chapter | 10.1002/9780470988923.ch5 |
| Ringer, Lymor | Role of p53 in cdk Inhibitor VMY-1-103-induced Apoptosis in Prostate Cancer | 2013/11/1 | report | 10.21236/ada592440 |
| Anurogo, Dito | Cancer Stem Cells | | journal-article | 10.55175/cdk.v48i11.1549 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/8/16 | peer-review | 10.1111/odi.13687/v1/review1 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/8/17 | peer-review | 10.1111/odi.13687/v1/review2 |
| Dutta, Anindya | Action of the p53 Effector, p2l, on its Targets: Cyclin cdk and PCNA | 1998/10/1 | report | 10.21236/ada368460 |
| Apodaca, Richard L. | Easily Calculate TPSA Descriptors from SMILES Strings Using Ruby CDK | | posted-content | 10.59350/8xxp3-b8077 |
| Roovers, Kristin | Role of Cyclin D1 and cdk Inhibitors in Breast Cancer Pathogenesis | 2002/5/1 | report | 10.21236/ada407447 |
| Apodaca, Richard L. | MX Performance Comparison #2: Exhaustive Ring Perception in MX and CDK | | posted-content | 10.59350/tv70e-5c238 |
| Kawauchi, Takeshi | Extra‐cell cycle regulatory functions of cyclin‐dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders | 2013/3 | journal-article | 10.1111/gtc.12029 |
| Rusli, Richardo | Retinitis Pigmentosa | | journal-article | 10.55175/cdk.v47i7.597 |
| Durandau, Eric | Cross-regulation between CDK and MAPK control cellular fate | | posted-content | 10.1101/274787 |
| Ringer, Lymor | Role of p53 in cdk Inhibitor VMY-1-103-Induced Apoptosis in Prostate Cancer | 2012/9/1 | report | 10.21236/ada567635 |
| Yu, Bo | Downregulation of Cyclin D1 Alters cdk 4- and cdk 2-Specific Phosphorylation of Retinoblastoma Protein | 2000/6 | journal-article | 10.1006/mcbr.2000.0238 |
| Cheng, Weiyan | Recent development of CDK inhibitors: An overview of CDK/inhibitor co-crystal structures | 2019/2 | journal-article | 10.1016/j.ejmech.2019.01.003 |
| Apodaca, Richard L. | Open Benchmarks for Cheminformatics: First Performance Comparison Between CDK and MX | | posted-content | 10.59350/7nc6k-w4216 |
| Cyclin‐Dependent Protein Kinase (
CDK
) | | other | 10.1002/0471684228.egp02997 |
| Srivastava, Mansi | Lineage-specific CDK activity dynamics characterize early mammalian development | | posted-content | 10.1242/prelights.38013 |
| Cyclin dependent kinase (CDK) | 2010/11 | journal-article | 10.1038/scibx.2010.1319 |
| Cyclin-Dependent Protein Kinases (CDK) | 2008 | book-chapter | 10.1007/978-1-4020-6754-9_3981 |
| Nishizawa, Masafumi | Phosphorylation of Sic1, a Cyclin-dependent Kinase (Cdk) Inhibitor, by Cdk Including Pho85 Kinase Is Required for Its Prompt Degradation | 1998/9 | journal-article | 10.1091/mbc.9.9.2393 |
| CDK | 2006 | book-chapter | 10.1007/3-540-29623-9_10003 |
| Wysocki, Robert | CDK Pho85 targets CDK inhibitor Sic1 to relieve yeast G1 checkpoint arrest after DNA damage | 2006/10 | journal-article | 10.1038/nsmb1139 |
| Mahendra, Cipta | Peutz-Jeghers Syndrome | | journal-article | 10.55175/cdk.v48i12.1574 |
| ., Sukamto | Penanganan Ketoasidosis Diabetik pada Anak | | journal-article | 10.55175/cdk.v49i9.2039 |
| Katz, Max | RichFaces CDK: Building Custom Components | 2011 | book-chapter | 10.1007/978-1-4302-3450-0_14 |
| Lawrenti, Hastarita | Hemofilia dan Perkembangan Terapinya | | journal-article | 10.55175/cdk.v48i9.1496 |
| Figure 4: The efficiency of tumor markers in distinguish CDK patients with normal serum creatinine from healthy controls. | | component | 10.7717/peerj.19240/fig-4 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/10/7 | peer-review | 10.1111/odi.13687/v2/review1 |
| Apodaca, Richard L. | Cheminformatics for the Web: Convert SD Files to HTML with Ruby CDK | | posted-content | 10.59350/gvwgq-b0x50 |
| Yuliana, Jeni | Aspek Klinis Ambliopia | | journal-article | 10.55175/cdk.v49i1.1639 |
| Sanchez-Diaz, Alberto | The Mitotic Exit Network and Cdc14 phosphatase initiate cytokinesis by counteracting CDK phosphorylations and blocking polarised growth | 2012/8/29 | journal-article | 10.1038/emboj.2012.224 |
| Pérez-Hidalgo, Livia | CDK Inhibitors | 2013 | book-chapter | 10.1007/978-1-4419-9863-7_12 |
| Apodaca, Richard L. | From InChI to Image with Ruby Open Babel and Ruby CDK | | posted-content | 10.59350/r891p-vmx14 |
| Chandra, Rudi | Tatalaksana Melanoma Maligna Kutaneus | | journal-article | 10.55175/cdk.v48i7.1453 |
| Turner, N. | Targeting the CDK 4-6 pathway | 2019/3 | journal-article | 10.1016/s0960-9776(19)30078-5 |
| Ogata, Ryohei | Resistance to cyclin-dependent kinase (CDK) 4/6 inhibitors confers cross-resistance to other CDK inhibitors but not to chemotherapeutic agents in breast cancer cells | 2021/1 | journal-article | 10.1007/s12282-020-01150-8 |
| Fig. 1. Ovarian enlargement and lack of blood flow in the CDK regimen with a full bladder | | component | 10.17816/psaic575-154 |
| Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor | | component | 10.1021/acs.oprd.1c00255.s001 |
| Lawrensia, Sherly | Diagnosis dan Tatalaksana Artritis Tuberkulosis | | journal-article | 10.55175/cdk.v47i8.773 |
| Teo, Gloria | Diagnosis dan Tatalaksana Kegawatdaruratan Hiperkalemia | | journal-article | 10.55175/cdk.v48i8.1447 |
| Aprelikova, Olga | Both p16 and p21 Families of Cyclin-dependent Kinase (CDK) Inhibitors Block the Phosphorylation of Cyclin-dependent Kinases by the CDK-activating Kinase | 1995/8 | journal-article | 10.1074/jbc.270.31.18195 |
| Nitiyoso, Nugroho | Aspek Imunitas pada COVID-19 | | journal-article | 10.55175/cdk.v48i9.1497 |
| ., Suharto | Fisioterapi Kasus Cerebral Palsy Kuadriplegia Spastik | | journal-article | 10.55175/cdk.v49i9.2036 |
| Meijer, Laurent | CDK Inhibitors | 2002 | book-chapter | 10.1016/b978-012476249-7/50008-4 |
| p27
Kip1−/−
Strain 3 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg10 |
| | | grant | 10.55776/p19894 |
| Febriana, Lydia | Suplemen untuk Terapi Obesitas | | journal-article | 10.55175/cdk.v49i0.1964 |
| When a CDK Is Really a Transcription Factor | 2005/1/11 | journal-article | 10.1126/stke.2662005tw14 |
| Prasetio, Adrian | Gangguan Psikiatri Terkait Kafein | | journal-article | 10.55175/cdk.v47i7.603 |
| EMPIAR dataset | | | 10.6019/empiar-10561 |
| Dai, Yun | CDK Inhibitors in Multiple Myeloma | 2008 | book-chapter | 10.1007/978-1-59745-564-0_22 |
| Lawrensia, Sherly | Lung Abscess: Diagnosis and Treatment | | journal-article | 10.55175/cdk.v48i5.1373 |
| Fauzi, Ahmad | Haglund Deformity: Diagnosis and Treatment | | journal-article | 10.55175/cdk.v49i10.2067 |
| Yahya, Willy | Retinopati Prematuritas : Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v47i10.1080 |
| RAYNAL, S | DIFFERENTIAL-EFFECTS OF TRANSFORMING GROWTH-FACTOR-BETA-1 ON PROTEIN-LEVELS OF P21 WAF AND CDK-2 AND ON CDK-2 KINASE-ACTIVITY IN HUMAN RD AND CCL64 MINK LUNG-CELLS | | journal-article | 10.3892/ijo.7.2.337 |
| Lone, Waseem Iqbal | Discovery of Colchicine Aryne Cyclo-Adduct as a Potent Molecule for the Abrogation of Epithelial to Mesenchymal Transition Via Modulating Cell Cycle Regulatory Cdk-2 and Cdk-4 Kinases | | posted-content | 10.2139/ssrn.4814175 |
| Cyclin dependent kinase (CDK) | 2010/3 | journal-article | 10.1038/scibx.2010.272 |
| Futcher, A. B. | General Methods for Identifying G1-Phase Substrates of Cdk Protein Kinases. | 1996/6/1 | report | 10.21236/ada323678 |
| Nitiyoso, Nugroho | Pilihan Pengobatan Sistemik pada Psoriasis | | journal-article | 10.55175/cdk.v49i3.1775 |
| Henri, P. | Psoriatic epidermis is associated with upregulation of
CDK
2 and inhibition of
CDK
4 activity | 2020/3 | journal-article | 10.1111/bjd.18178 |
| Cyclin dependent kinase (CDK) | 2012/4 | journal-article | 10.1038/scibx.2012.385 |
| Karyadi, Erlinda | Cutaneous Mucormycosis | | journal-article | 10.55175/cdk.v49i2.1740 |
| Larochelle, Stéphane | CDK-Activating Kinases: Detection and Activity Measurements | | book-chapter | 10.1385/1-59259-857-9:279 |
| Bisbis, Badia | Cyclin-dependent Kinase (CDK) Inhibitors Regulate the CDK-Cyclin Complex Activities in Endoreduplicating Cells of Developing Tomato Fruit | 2006/3 | journal-article | 10.1074/jbc.m506587200 |
| Lukito, Johan Indra | Tinjauan atas Terapi Insulin | | journal-article | 10.55175/cdk.v47i9.917 |
| Dai, Yun | CDK Inhibitors in Leukemia and Lymphoma | 2019/9/17 | book-chapter | 10.1201/9780429114670-15 |
| Karyadi, Erlinda | Cutaneous Mucormycosis | | journal-article | 10.55175/cdk.v49i2.1726 |
| Cicenas, Jonas | CDK Inhibitors and FDA: Approved and Orphan | | journal-article | 10.3390/cancers16081555 |
| Müllers, Erik | Cdk activity drives senescence from G2 phase | | posted-content | 10.1101/041723 |
| Putri, Zanty Rakhmania | Bell’s Palsy: Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v49i8.1986 |
| Pricelda, Alicia | Tren Terapi Age-Related Macular Degeneration | | journal-article | 10.55175/cdk.v48i12.1584 |
| -, Tommy | Angina Prinzmetal - Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v48i6.1431 |
| p27
Kip1−/−
Strain 2 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg9 |
| Chandra, Rudi | Pilihan Pengobatan Dermatologis Penuaan Periorbital | | journal-article | 10.55175/cdk.v47i12.1241 |
| Morgan, David O. | Principles of CDK regulation | 1995/3 | journal-article | 10.1038/374131a0 |
| Mahendro, Della Sulamita | Penggunaan Antivirus untuk COVID-19 | | journal-article | 10.55175/cdk.v48i7.1459 |
| Kristiningrum, Esther | Penggunaan Hydroxychloroquine dalam Tatalaksana Covid-19 | | journal-article | 10.55175/cdk.v47i12.1246 |
| Suryani, Adelia | Faktor-Faktor yang Memengaruhi Pigmentasi Manusia | | journal-article | 10.55175/cdk.v47i11.1195 |
| Permasutha, Made Bayu | Tinjauan atas Kanker Rongga Mulut | | journal-article | 10.55175/cdk.v48i3.1327 |
| Kusumo, Inosensia Diajeng | Tinjauan Atas Pioderma | | journal-article | 10.55175/cdk.v49i4.1822 |
| CDK Inhibitor Triples PFS in Breast Cancer | 2013/1/1 | journal-article | 10.1158/2159-8290.cd-nb2012-149 |
| ASCO TAPUR, CDK Studies Endeavor to Fill Gaps in Personalized Cancer Care Research | 2024/12/1 | dataset | 10.1200/acon.24.00037 |
| EMPIAR dataset | | | 10.6019/empiar-10431 |
| Johan, Michael | Evaluasi dan Tatalaksana Hipernatremia | | journal-article | 10.55175/cdk.v48i6.1441 |
| Palacios Blanco, Inés | CDK phospho-regulation of the Rad51-accessory factor Sfr1 and its role in meiotic recombination | | dissertation | 10.14201/gredos.161088 |
| Afifah Nurullah, Fitri | Tinjauan atas N-Nitrosodimethylamine (NDMA) | | journal-article | 10.55175/cdk.v47i12.1249 |
| -, Carlson | Tatalaksana Demam pada Anak | | journal-article | 10.55175/cdk.v47i11.1200 |
| Decision letter: CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading | 2016/12/19 | peer-review | 10.7554/elife.23352.021 |
| Fanardy, Angeline | Toksin Botulinum untuk Kasus Urogenital | | journal-article | 10.55175/cdk.v48i3.1337 |
| Dinari, Nur Alfi | Miopia: Etiologi dan Terapi | | journal-article | 10.55175/cdk.v49i10.2069 |
| Ciatawi, Kartini | Patofisiologi Spinal Cord Injury | | journal-article | 10.55175/cdk.v49i5.1848 |
| Ciatawi, Kartini | Patofisiologi Spinal Cord Injury | | journal-article | 10.55175/cdk.v49i9.2032 |
| Apodaca, Richard L. | CampDepict: Building a Simple SMILES Depict Web Application With JRuby, Structure CDK, and Camping | | posted-content | 10.59350/d2m6v-tag27 |
| Stanley, Jone A. | Chromium-VI arrests cell cycle and decreases granulosa cell proliferation by down-regulating cyclin-dependent kinases (CDK) and cyclins and up-regulating CDK-inhibitors | 2011/7 | journal-article | 10.1016/j.reprotox.2011.05.007 |
| Renita Sanyasi, Rosa De Lima | Sindrom Mona Lisa | | journal-article | 10.55175/cdk.v48i1.1258 |
| Feinberg, Bruce A. | Prescribing preferences for hormone sensitive (HR+) metastatic breast cancer (mBC) in the CDK 4/6 inhibitor (CDK 4/6i) era. | 2020/5/20 | journal-article | 10.1200/jco.2020.38.15_suppl.e13058 |
| Wijaya, Sandy | Diagnosis dan Tatalaksana Polisitemia Vera | | journal-article | 10.55175/cdk.v47i7.596 |
| Lawrenti, Hastarita | Penghambat Immune Checkpoint untuk Terapi Kanker | | journal-article | 10.55175/cdk.v49i0.1966 |
| Shamsi, Zahra | Concestor kinase activation mechanism uncovers the cyclin dependence of CDK family kinases | | posted-content | 10.1101/410902 |
| Lukito, Johan Indra | Gunakan Insulin dengan CERMAT | | journal-article | 10.55175/cdk.v47i10.1093 |
| Cherub, Jane | Terapi Antikoagulan pada COVID-19 | | journal-article | 10.55175/cdk.v48i6.1436 |
| Setiawan, Michael | Mielopati Non Kompresif: Pendekatan Diagnosis | | journal-article | 10.55175/cdk.v47i9.909 |
| Dewi, Nadia Puspa | Aspek Klinis Dermatitis Seboroik | | journal-article | 10.55175/cdk.v49i6.1881 |
| Ratna Sari, Ihda Zuyina | Gambaran Sistiserkosis dan Taeniasis | | journal-article | 10.55175/cdk.v49i3.1768 |
| Mueller, Daniel | Abstract 2821: Characterization of CDK inhibitors in a biochemical assay using a comprehensive panel of human CDK-cyclin complexes | 2016/7/15 | journal-article | 10.1158/1538-7445.am2016-2821 |
| Besser, Alexandra | CDK Inhibitors in Normal and Malignant Cells | 2023 | book-chapter | 10.1016/b978-0-12-821618-7.00221-2 |
| Mahendrakrisna, Daniel | Tatalaksana Epilepsi Refrakter | | journal-article | 10.55175/cdk.v47i9.911 |
| p27
Kip1−/−
Strain 1 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg8 |
| Carrieri, Francesca Anna | CDK
1 and
CDK
2 regulate
NICD
1 turnover and the periodicity of the segmentation clock | 2019/7 | journal-article | 10.15252/embr.201846436 |
| Dianky, Amanda | Peran Nutrigenomik pada Tata Laksana Obesitas | | journal-article | 10.55175/cdk.v49i0.1965 |
| 4-Arylazo-3, 5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects | | component | 10.1021/jm0605740.s001 |
| Mahendra, Cipta | Terapi Berbasis Sel: Perkembangan Terkini | | journal-article | 10.55175/cdk.v49i3.1769 |
| Clinical Trial in Healthy Volunteers and Subjects With CDK | | journal-article | 10.31525/ct1-nct03893799 |
| Cyclin dependent kinase (CDK); p53 | 2012/10 | journal-article | 10.1038/scibx.2012.1028 |
| CRESCENZI, ELVIRA | Association of Bcl‐2 with Cyclin A/Cdk‐2 Complex and Its Effects on Cdk‐2 Activity | 2002/11 | journal-article | 10.1111/j.1749-6632.2002.tb04647.x |
| Decision letter: CDK control pathways integrate cell size and ploidy information to control cell division | 2020/12/20 | peer-review | 10.7554/elife.64592.sa1 |
| Wijaya, Lupita | Tatalaksana Nyeri Neuropatik Perifer dengan Sediaan Patch | | journal-article | 10.55175/cdk.v48i9.1484 |
| First CDK 4/6 Inhibitor Heads to Market | 2015/4/1 | journal-article | 10.1158/2159-8290.cd-nb2015-028 |
| Irsyada Yusuf, Amry | Diagnosis dan Tatalaksana Kriptorkhismus | | journal-article | 10.55175/cdk.v48i3.1330 |
| Wijaya, Meiliyana | Meningitis Kriptokokus pada Penderita HIV | | journal-article | 10.55175/cdk.v48i1.1256 |
| Tan, Christine | Trombosis pada Pasien COVID-19 | | journal-article | 10.55175/cdk.v48i12.1571 |
| Chandra, Rudi | Aspek Dermatologi Penuaan Kulit Periorbital | | journal-article | 10.55175/cdk.v47i9.920 |
| -, Cecile | Diagnosis dan Tatalaksana Paroxysmal Nocturnal Hemoglobinuria | | journal-article | 10.55175/cdk.v48i7.1452 |
| Decker, T | Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27 | 2002/3/1 | journal-article | 10.1038/sj.leu.2402389 |
| Mostafa, Heba H. | Herpes Simplex Virus 1 Upregulates p35, Alters CDK-5 Localization, and Stimulates CDK-5 Kinase Activity during Acute Infection in Neurons | 2015/5 | journal-article | 10.1128/jvi.00106-15 |
| Sondhi, Sham M. | Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases | 2006/6 | journal-article | 10.1016/j.bmc.2006.01.054 |
| Falco, Giulia De | Cdk Inhibitors: Background and Introduction | | book-chapter | 10.1385/1-59259-401-8:01 |
| Kumala, Marcia | Suplementasi Vitamin B1 untuk Pasien Sepsis | | journal-article | 10.55175/cdk.v47i8.783 |
| Bird, R.Curtis | The Cyclin/Cyclin-Dependent Kinase (cdk) Complex | 1997 | book-chapter | 10.1016/b978-012100160-5/50006-3 |
| A novel and robust molecular switch actuating the quantitative model of eukaryotic Cdk control | | proceedings-article | 10.18699/sbb-2022-104 |
| Luminturahardjo, Winarko | Peranan Probiotik dalam Penanganan Infeksi COVID-19 | | journal-article | 10.55175/cdk.v48i5.1371 |
| Supit, Brigita | Infeksi TORCH Maternal dan Kongenital | | journal-article | 10.55175/cdk.v48i9.1499 |
| Wisesaputra, Tjok Agung Purnama | Best Vitelliform Dystrophy | | journal-article | 10.55175/cdk.v47i7.599 |
| Review for "Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p27" | 2021/6/23 | peer-review | 10.1098/rsob.210125/v1/review2 |
| Title | Description | Published | Added |
| github.com-angular-components_-_2021-03-13_17-17-56 | Component infrastructure and Material Design components for Angular Official components for Angular The Angular team builds and maintains both common UI components and tools to help you build yourown custom components. The team maintains several npm packages. | Package | Description | Docs || ------------------------- | ----------------------------------------------------------------------------------- | ---------------- || @angular/cdk | Library that helps you author custom UI components with common interaction patterns | Docs || @angular/material | Material Design UI components for Angular applications | Docs || @angular/google-maps | Angular components built on top of the Google Maps JavaScript API | Docs || @angular/youtube-player | Angular component built on top of the YouTube Player API | Docs | Quick links Documentation, demos, and guides | Frequently Asked Questions | Community Google group | Contributing | StackBlitz Template Getting started See our Getting Started Guide if yo; | 2021 | 2021-03-13T21:27:21Z |
| EP 12: Kelsey Smith - Abducted In Broad Daylight | Kelsey Smith was just 18 years old when she was abducted from a Target parking lot in Overland Park, Kansas in June 2007. Finding her would take a battle with a cellular phone company and heartbreaking surveillance video from Target, that shows that no one is ever really safe, even if you're running a simple errand in broad daylight. A special thank you to Kelsey's mom, Missey Smith, for speaking with me for this episode. To learn more about the Kelsey Smith Foundation and the Kelsey Smith Act, please visit kelseysarmy.org. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode: - Summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/cdk/13112 - Like Music (cdk Mix) by c; | 2017 | 2023-07-08T12:40:23Z |
| Ep 10 Part 1: Kristine Bunch's Nightmare | In part 1 of this episode, you'll hear about one woman's nightmare come true. In 1995, 21-year-old Kristine Bunch was abruptly awoken in the early morning hours to discover that her house was on fire. After escaping the flames, she watched in horror as firefighters were unable to save her 3-year-old son who was still trapped inside. Within hours of being released from the hospital, she discovered that detectives had a theory about the fire - someone had started the fire on purpose, and their main suspect was Kristine. A special thank you to Kristine Bunch for helping me tell her story.Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie. Music featured in this episode: Like Music (cdk Mix) by cdk (c) copyright 2015 Licensed under a Creative Commons Attribution Share-Alike (3.0) license. htt; | 2016 | 2023-07-08T12:43:39Z |
| Linea Dorada | Tracklist: 1. El numero uno 2. La camioneta gris 3. La bronco negra 4. Chico Fuentes 5. Setecientas libras 6. Doctor Fonseca 7. Juan Ramos 8. Rosita la morena 9. Crimen en Chihuahua 10. La entallada 11. Gumaro Vazquez 12. Candido Rodriguez 13. El culichi 14. Esperanza Valero 15. Pedro Paez 16. Los traficantes 17. La ley del contrabandista 18. Los dos contrabandistas 19. El aguila real 20. El corrido de Gabino | 2002 | 2024-11-21T12:12:01Z |
| Faulkner v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-10-12T07:17:13Z |
| Historic Preservation Awards 2013 | | 2013 | 2016-10-07T01:03:50Z |
| github.com-localstack-localstack_-_2023-09-30_01-52-12 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline :zap: Join the LocalStack Insiders program to help us shape the future of LocalStack! Test drive new features & engage in conversations with us so we can learn from your use cases :zap: LocalStack provides an easy-to-use test/mocking framework for developing cloud applications. Overview • Install • Example • Run • Usage • Releases • Contributing 📖 Docs • 💻 Pro version • ☑️ LocalStack coverage Overview LocalStack is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack s; | 2023 | 2023-09-30T05:53:41Z |
| github.com-DovAmir-awesome-design-patterns_-_2022-11-09_07-18-54 | A curated list of software and architecture related design patterns. Awesome Software and Architectural Design Patterns A curated list of software and architecture related design patterns. Software design pattern - A general, reusable solution to a commonly occurring problem within a given context in software design. It is a description or template for how to solve a problem that can be used in many different situations. Contents Programming language design patterns General Architecture Cloud Architecture Serverless Architecture Micro services & Distributed Systems Internet of things Big Data Databases and storage Docker and DevOps Mobile Front End Development Security Programming Language Design Patterns AngularJS design patterns C# design-patterns design-patterns-for-human - ultra simplified explanation to design patterns. Design Patterns Library C++ design-patterns Closure design-patterns Go design-patterns Java sourcemaking - patterns and anti patterns. oodesign - patterns catalog ; | 2022 | 2022-11-09T18:39:55Z |
| github.com-aws-aws-cdk_-_2020-03-31_08-47-24 | The AWS Cloud Development Kit is a framework for defining cloud infrastructure in code AWS Cloud Development Kit (AWS CDK) The AWS Cloud Development Kit (AWS CDK) is an open-source software developmentframework to define cloud infrastructure in code and provision it through AWS CloudFormation. It offers a high-level object-oriented abstraction to define AWS resources imperatively usingthe power of modern programming languages. Using the CDK’s library ofinfrastructure constructs, you can easily encapsulate AWS best practices in yourinfrastructure definition and share it without worrying about boilerplate logic. The CDK is available in the following languages: JavaScript, TypeScript ( Node.js ≥ 10.3.0 ) Python ( Python ≥ 3.6 ) Java ( Java ≥ 8 and Maven ≥ 3.5.4 ) .NET ( .NET Core ≥ 3.1 ) Developer Guide | CDK Workshop | Getting Started | API Reference | Examples | Getting Help | RFCs | Roadmap Developers use the [CDK framework] in one of thesupported programming languages to d; | 2020 | 2020-03-31T09:11:59Z |
| Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses vasculogenic mimicry and proliferation of highly aggressive pancreatic cancer PaTu8988 cells. | This article is from BMC Cancer , volume 14 . Abstract Background: Pancreatic cancer is one of the most aggressive human malignancies with a extremely low 5-year survival rate. Hence, the search for more effective anti-pancreatic cancer agents is urgent. Methods: PaTu8988 pancreatic cancer cells were treated with different concentrations of suberoylanilide hydroxamic acid (SAHA), cell survival, proliferation, migration and vasculogenic mimicry (VM) were analyzed. Associated signaling changes were also analyzed by RT-PCR and Western blots. Results: Here, we reported that SAHA, a histone deacetylase inhibitor (HDACi), exerted significant inhibitory efficiency against pancreatic cancer cell survival, proliferation, migration and VM. SAHA dose-dependently inhibited PaTu8988 pancreatic cancer cell growth with the IC-50 of 3.4 ± 0. 7 μM. Meanwhile, SAHA suppressed PaTu8988 cell cycle progression through inducing G2/M arrest, which was associated with cyclin-dependent kinase 1 (CDK-1)/; | 2014 | 2014-10-21T20:47:25Z |
| Death is a silent room | | 1965 | 2023-08-29T22:36:40Z |
| CIA Reading Room cia-rdp83m00914r002700200048-3: REQUEST FOR SPEAKING ENGAGEMENT - CHIEF EXECUTIVE S FORUM, PALM SPRINGS, CALIFORNIA | Approved For Release 2007/03/15: CIA-RDP83M0091 2-fR009g~l~ 3 OEXA 82-0226 MEMORANDUM FOR: Director of Central Intelligence Director, fT-ice o External Affairs STAT SUBJECT: Request for Speaking Engagement - Chief Executive's Forum, Palm Springs, California 1. Action Requested: Regret an invitation to speak to the Chief Executive's Forum in Palm Springs on 21 February. 2. Background: Public Affairs received this invitation by telephone from Leo Greenland, Program Chairman of the Chief Executive's For m. A formal invitation is in the mail. Greenland says you met at home in New York. You are committed to Palm Beach 19-23 February. 3. Recommendation: To ease Greenland's problem in arranging for another speaker, authorize Public Affairs to telephone your regrets. Director of Central Intelligence (Date) /s/ _ - ___ T2- Director of Central Intelligence (Date) STAT STAT OEXA/CEW/cdk/27 Jan 82/x7676 Distribution: Orig - Addressee DDCI - ER 1 - D/OEXA 1 - OEXA Registry 1 - C/PAD (To Be Returned; | 1982 | 2025-02-22T15:15:54Z |
| sinceretheory.podcast_v1.3 | 01 I've switched to Mac, goodbye Windows. The Bluescreen is going through reorganization. What is Google Pack? 02 Louis Braille's birthday Download File List iPod with WiFi 03 Flickr: "2.5.8." by powerbooktrance (license) Music: CDK - Midnight Bliss (Green Dub Mix) (license) I'm a little upset about del.icio.us being swooped by Yahoo! | | 2006-01-05T18:47:03Z |
| Vicki Winans | Tracklist: 1. Work It Out 2. Prelude: We Shall Overcome 3. Precious Lord (A Tribute To Dr. Martin Luther King) 4. Stand Up and Praise Him 5. We Shall Behold Him (New Rendition) 6. The Only One 7. Suddenly 8. I Remember When 9. You Never Left Me 10. Believing Is Seeing 11. Mary Did You Know | 1994 | 2017-10-20T11:51:56Z |
| CELEBRITY MOTOR CAR, LLC v. CDK GLOBAL, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2025-06-17T09:38:39Z |
| DTIC ADA372217: Cyclin D1, Anchorage-Independent Growth and Breast Cancer. | Derangements in the cell cycle machinery contribute to uncontrolled cell growth and tumorigenesis. Regulators of GI progression including cyclin D1 and the cyclin-dependent kinase inhibitors p21 and p27 appear to be of particular importance in the pathogenesis of breast cancer. Our data show that the overexpression of cyclin D1 leads to a compensatory increase in the cdk inhibitor p21, and suggest that this increase can weaken the value of cyclin D1 overexpression as a diagnostic indicator. We suggest that aggressive breast cancer will involve both (1) overexpression of cyclin D1 and (2) the failure to undergo a compensatory upregulation of cdk inhibitors. The specific aims are designed to test these hypotheses in cell culture models, nude mice, and breast cancer biopsies. We have thus far determined that p21- null fibroblasts are adhesion-dependent and suitable for use to study the role of p21 in negating the effect of cyclin D1 overexpression on anchorage-independent cell cycle progr; | 1998 | 2018-04-26T23:30:00Z |
| Tumor-suppressing viruses, genes, and drugs : innovative cancer therapy approaches | 1 online resource (xv, 425 pages) : // Includes bibliographical references and index // Ch. 1. Oncolytic viruses: virotherapy for cancer -- Ch. 2. Reovirus therapy of Ras-associated cancers -- Ch. 3. Oncolytic herpes simplex virus (G207) therapy: from basic to clinical -- Ch. 4. p53 and its targets -- Ch. 5. Prospects for tumor suppressor gene therapy: RB as an example -- Ch. 6. CDK inhibitors: genes and drugs -- Ch. 7. CDK inhibitors: small molecular weight compounds -- Ch. 8. NF1 and other RAS-binding peptides -- Ch. 9. Cytoskeletal tumor suppressor genes -- Ch. 10. TGF-[beta] signaling and carcinogenesis -- Ch. 11. DAN gene -- Ch. 12. Design of hammerhead ribozymes and allosterically controllable maxizymes for cancer gene therapy -- Ch. 13. Inhibitors of angiogenesis -- Ch. 14. Geranylgeranylated RhoB mediates the apoptotic and antineoplastic effects of farnesyltransferase inhibitors: new insights into cancer cell suicide -- Ch. 15. RAS binding compounds -- Ch. 16. Actin-binding dru; | 2002 | 2020-05-15T01:03:07Z |
| Swift Flies the Falcon | | 1939 | 2023-11-06T18:03:35Z |
| Het Utrechts Archief 807733 | Het Utrechts Archief catalog number: 807733 Description (Dutch): Afbeelding van de CDk-bak van het ontspoorde electrische treinstel nr. 302 (mat. 1940) van de N.S. bij de spoorbrug over de Haven te Maassluis. | 1956 | 2021-02-26T01:03:42Z |
| CDK Global, LLC al v. Tulley Automotive Group, Inc. | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2017-07-24T21:20:07Z |
| Boleros | Tracklist: 1. El Reloj/Perfidia/Mira Gue Eres Linda/Maria Elena/Aquellos Ojos Verdes/El Reloj/Te Quiero Dijiste/La Barca/Historia De Un Amor/El Reloj/Siboney/Sabor A Mi/Quiereme Mucho/El Reloj/Amapola/Angelitos Negros/Solamente Un Vez/Besame Mucho/El Reloj/Vamos A La Cama/La Conga 2. Me Lo Dijo Adela/Mi Vaca Lechera/Maria Christina Me Quiere Governar/Tequila/La Conga/Salud, Dinero Y Amor/Cielito Lindo/La Pachanga/La Gallina Papanatas/La Conga/La Bamba/La Raspa/La Cucaracha/La Conga/Se Va El Caiman/Todos Queremos Mas/Baio De Ana/La Conga/Vamos A La Cama | 1988 | 2024-07-11T07:14:09Z |
| Persuading science : the art of scientific rhetoric | xi, 212 p. : 24 cm // Includes bibliographical references and index | 1991 | 2023-12-23T17:00:10Z |
| Pathfinders in Medicine. | | 1929 | 2023-12-22T15:43:03Z |
| The Future of Public Access TV and The Internet | Mark Cooper of the Consumer Federation of America speaks with local independent radio host John Grebe about current bills in Congress affecting the future of Public Access Television and the Internet. We also hear from Jason Crow, Access Coordinator of Cambridge Community Television and Michael Eisenmenger of Manhattan Neighborhood Network about how pending legislation in Congress takes away local control of media and places more power in the hands of Big Cable and Telephone companies. Click here to listen to the ACMEBoston Podcast February 11, 2006. Also discussed is the issue of Network Neutrality which Free Press , the national media reform organization, describes as "the guiding principle of the Internet that fosters open competition and innovation, while preserving the independence and accessibility of the World Wide Web" - Free Press, Net Freedom Now . To take a closer look at these issues, we'll hear John Grebe's interview from his program, "Sounds of Dissent" broadcast live on ; | 2006 | 2006-07-27T08:21:29Z |
| DTIC ADA443059: Suppression of Prostate Cancer by PTEN and p18(INK4C) | The Rb pathway suppresses tumorigenesis by constraining G1 cell cycle progression. Functional inactivation or reduction of this pathway is a common event found in many types of human tumors. To test how the Rb pathway interacts with other cellular pathways in tumor suppression, we characterized mice with combined mutations in the CDK inhibitor p18 (sub Ink4c) and the lipid phosphatase Pten, which regulates cell growth and survival. Thep18-/-;Pten +/-double mutant mice develop prostate cancer in the anterior and dorsolateral lobes and thyroid C cell tumors with nearly complete penetrance, and pituitary tumors in both the anterior and intermediate lobes. AKT/PKB, an oncoprotein and downstream substrate of PTEN, was activated and accumulated at the plasma membrane in Pten+i. cells, and further activated and accumulated in the nucleus in p18-/-;Pten+/- tumor cells, suggesting a negative regulation of AKT by the Rb pathway. The remaining wildtype allele of Pten was lost at a high frequency ; | 2005 | 2018-05-31T00:40:44Z |
| The dynamics of strategy : mastering strategic landscapes of the firm | ix, 220 p. : 24 cm // Includes bibliographical references and index // 1. Introduction -- Pt. I. The Competitive Landscape -- 2. Models of Competition -- 3. Dynamics of Competition -- 4. Networks -- Pt. II. The Organizational Landscape -- 5. Organizational Dynamics -- 6. Managing Firm Complexity -- 7. Co-Evolution -- 8. Conclusion | 2009 | 2023-10-02T09:51:36Z |
| Differential roles of Smad2 and Smad3 in the regulation of TGF-?1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1. | This article is from Molecular Cancer , volume 10 . Abstract Background: Progression of pancreatic ductal adenocarcinoma (PDAC) is largely the result of genetic and/or epigenetic alterations in the transforming growth factor-beta (TGF-β)/Smad signalling pathway, eventually resulting in loss of TGF-β-mediated growth arrest and an increase in cellular migration, invasion, and metastasis. These cellular responses to TGF-β are mediated solely or partially through the canonical Smad signalling pathway which commences with activation of receptor-regulated Smads (R-Smads) Smad2 and Smad3 by the TGF-β type I receptor. However, little is known on the relative contribution of each R-Smad, the possible existence of functional antagonism, or the crosstalk with other signalling pathways in the control of TGF-β1-induced growth inhibition and cell migration. Using genetic and pharmacologic approaches we have inhibited in PDAC cells endogenous Smad2 and Smad3, as well as a potential regulator, th; | 2011 | 2014-10-29T05:01:17Z |
| DTIC ADA474451: Mechanism of Antineoplastic Action of Bisperoxovanadium Compound | This work describes studies into the mechanism of action of bisperoxovanadium (bpVs) compounds and into the basic biology and regulation of Cdc25A phosphatase. The bpVs cause phase-specific cell cycle arrest (G1/S), dose-dependent inhibition of Cdk activity, and persistent Rb hypophosphorylation upon release from serum starvation, consistent with Cdc25A inhibition. Further, they cause p53-independent apoptosis. Oxidative stress and DNA damage do not appear to be involved in their mechanism of action, given that: p53 is not induced by bpV(Me2Phen); p53 and p21 status do not affect IC50; depletion of glutathione or supplementation with antioxidants does not affect IC50, in contrast to other heavy metal-based agents. With respect to regulation, the Cdc25A nuclear localization signal (NLS) was identified and characterized. Data suggest that phosphorylation of S292, adjacent to the NLS, may promote nuclear localization. In the unperturbed cell cycle, S292 phosphorylation, a Chk1/2 target, a; | 2005 | 2018-06-15T10:53:58Z |
| the new testament in the original greek | | 1928 | 2025-06-16T23:17:47Z |
| the secrets of studying english | | 1980 | 2023-07-21T01:18:46Z |
| The influence of negative training set size on machine learning-based virtual screening. | This article is from Journal of Cheminformatics , volume 6 . Abstract Background: The paper presents a thorough analysis of the influence of the number of negative training examples on the performance of machine learning methods. Results: The impact of this rather neglected aspect of machine learning methods application was examined for sets containing a fixed number of positive and a varying number of negative examples randomly selected from the ZINC database. An increase in the ratio of positive to negative training instances was found to greatly influence most of the investigated evaluating parameters of ML methods in simulated virtual screening experiments. In a majority of cases, substantial increases in precision and MCC were observed in conjunction with some decreases in hit recall. The analysis of dynamics of those variations let us recommend an optimal composition of training data. The study was performed on several protein targets, 5 machine learning algorithms (SMO, Naïve B; | 2014 | 2014-10-19T07:35:32Z |
| Palbociclib: an evidence-based review of its potential in the treatment of breast cancer. | This article is from Breast Cancer : Targets and Therapy , volume 6 . Abstract Cellular proliferation, growth, and division following DNA (deoxyribonucleic acid) damage are tightly controlled by the cell-cycle regulatory machinery. This machinery includes cyclin-dependent kinases (CDKs) which complex with their cyclin partners, allowing the cell cycle to progress. The cell-cycle regulatory process plays a critical role in oncogenesis and in the development of therapeutic resistance; it is frequently disrupted in breast cancer, providing a rational target for therapeutic development. Palbociclib is a potent and selective inhibitor of CDK4 and -6 with significant activity in breast cancer models. Furthermore, it has been shown to significantly prolong progression-free survival when combined with letrozole in the management of estrogen receptor-positive metastatic breast cancer. In this article we review the cell cycle and its regulatory processes, their role in breast cancer, and the rat; | 2014 | 2014-10-06T01:38:18Z |
| Roscovitine confers tumor suppressive effect on therapy-resistant breast tumor cells. | This article is from Breast Cancer Research : BCR , volume 13 . Abstract Introduction: Current clinical strategies for treating hormonal breast cancer involve the use of anti-estrogens that block estrogen receptor (ER)α functions and aromatase inhibitors that decrease local and systemic estrogen production. Both of these strategies improve outcomes for ERα-positive breast cancer patients, however, development of therapy resistance remains a major clinical problem. Divergent molecular pathways have been described for this resistant phenotype and interestingly, the majority of downstream events in these resistance pathways converge upon the modulation of cell cycle regulatory proteins including aberrant activation of cyclin dependent kinase 2 (CDK2). In this study, we examined whether the CDK inhibitor roscovitine confers a tumor suppressive effect on therapy-resistant breast epithelial cells. Methods: Using various in vitro and in vivo assays, we tested the effect of roscovitine on th; | 2011 | 2014-10-28T11:55:39Z |
| [CDK 064] Duke Flex - Duke Flex Ain't Dead | [CDK 064] Duke Flex - Duke Flex Ain't Dead | 2016 | 2020-01-05T21:40:28Z |
| DTIC ADA473781: Checkpoint Kinase-Dependent Regulation of DNA Repair and Genome Instability in Breast Cancer | DDB1, a component of a Cul4A ubiquitin ligase complex, promotes nucleotide excision repair (NER) and regulates DNA replication. We have investigated the role of human DDB1 in maintaining genome stability. DDB1-depleted cells accumulate DNA double strand breaks in widely dispersed regions throughout the genome and have activated ATM and ATR cell cycle checkpoints. Depletion of Cul4A yields similar phenotypes, indicating that an E3-ligase function of DDB1 is important for genome maintenance. In contrast, depletion of DDB2, XPA, or XPC does not cause activation of DNA damage checkpoints, indicating that defects in NER are not involved. One substrate of DDB1-Cul4A that is crucial for preventing genome instability is Cdt1. DDB1-depleted cells exhibit increased levels of Cdt1 protein and re-replication, despite containing other Cdt1 regulatory mechanisms. Accumulation of DNA damage, re-replication, and activation of checkpoint responses in DDB1-depleted cells requires entry into S-phase and ; | 2007 | 2018-06-15T04:56:11Z |
| The Stormy Petrel (Large Print Edition) | | 1991 | 2023-07-25T00:30:17Z |
| Bedienungsanleitung/Garantie CDK 676 Sing Along CD | | | 2021-05-16T13:06:38Z |
| DTIC ADA389310: Regulation of Ubiquitin Mediated Proteolysis of G1 Cyclins and the CDK Inhibitor p27 by the Cullin Gene Family in Normal and Tumorigenic Human Breast Cells | The periodicity of CDK activity provides the molecular basis for unidirectional cell cycle progression and is partly controlled by ubiquitin-mediated proteolysis of both cyclins and CDK inhibitors. Deregulated expression of G1 CDK inhibitors and G1 cyclins has been directly linked to breast cancer development. The mechanisms regulating the ubiquitination of these two protein families constitute essential components of G1 cell cycle control in mammalian cells. Polyubiquitination of proteins is known to be catalyzed by a cascade of enzymes: E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligating). Two issues critical to our understanding of the regulation of protein turnover are how E3 ligases target proteins for ubiquitination and how they themselves are regulated. We have found that cullins partner with another multigene family of evolutionarily conserved proteins, the ROC/APC11 family, to form a complex that contains E3 ubiquitin ligase activity. We have show; | 2000 | 2018-05-01T22:46:59Z |
| [CDK 023] Urban Bits | The second of CDKr’s Hip Hop themed compilations – this one is a covers filled release, with tracks from Combat Dave, Josstin Timberlake, Oxygenstar and more! Covers include tracks by Jay Z, KanYe West, Hurricane Chris and loads of others too. The artwork is by the supremely talented Sir Count Ville Von Konttinen III esq (AKA KeFF) – thanks for that mate! The full tracklist is after the jump! | 2008 | 2019-12-07T00:23:58Z |
| DTIC ADA410428: Development of Inhibitors That Selectively Disrupt Substrate Recognition by Cyclin-Dependent Kinases | Upregulation of cyclin/cdk activity and the resulting deregulation of the cell cycle is a common feature in the malignant transformation of breast epithelial cells and thus makes cyclin/cdks an attractive target for drug design. The long-term goal of our work is to develop inhibitors which inhibit cyclin/cdk activity by disrupting the interaction between cyclins and their substrates, an association that requires a sequence motif in the substrate termed a Cy motif. Cy or RXL motifs are general purpose motifs for the interaction of cellular factors with cyclins. Recent work in our laboratory has shown that these motifs are critical determinants of both substrate recognition and specificity and function by targeting molecules to particular cyclin/cdk complexes. During the first year of grant support, we have made significant advancements into understanding substrate recognition by cyclin-dependent kinases. This work provides the framework for the development of Cy motif-derived peptides a; | 2002 | 2018-05-11T22:33:13Z |
| DTIC ADA443026: Radiation Sensitization in Breast Cancer via Targeting Survivin Expression | We proposed to determine whether overexpression- of surviving results in radio resistance and the possible mechanisms; whether irradiation down regulates p34(CDC2) and its mechanism in vascular endothelium and whether CDK (cyclin dependent kinase) inhibitors sensitize it to radiation injury; the mechanism of surviving- deregulation in breast cancer and whether inhibition of surviving or its regulator, p34(CDC2) abolishes radio resistance. We found that overexpression of surviving leads to radiation resistance and CDK inhibitors result in radiosensitization. We also found that deregulation of surviving in breast cancer is mediated by Stat3 (Signal transducer and activator of transcription). Co-inhibition of surviving and Stat3 results in significantly increased sensitization of breast cancer. In the next two years, we will determine the biological significance of combining surviving inhibitors or CDK inhibitors with radiotherapy in xenograft models of breast cancer. The proposed study w; | 2005 | 2018-05-30T23:48:34Z |
| github.com-sindresorhus-awesome_-_2021-04-05_11-52-56 | 😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my blog and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Development Environment Entertainment Databases Media Learn Security Content Management Systems Hardware Business Work Networking Decentralized Systems Higher Education Events Testing Miscellaneous Related Platforms Node.js - Async non-blocking event-driven JavaScript ru; | 2021 | 2021-04-05T13:17:05Z |
| Chroniques syndicales internationalistes - CNT | La prochaine émission radio des Chroniques syndicales internationalistes sera demain, samedi 24 décembre 2022, à 11H30 sur Radio libertaire (89.4fm ou en ligne en direct sur http://media.radio-libertaire.org:8080/radiolib.mp3 , en podcast également), et animée par le secrétariat international de la CNT. Nous dédions cette émission aux camarades du Conseil Démocratique des Kurdes en France (CDK-F) en diffusant l'intégralité de leur conférence de presse qui a eu lieu le vendredi 23 décembre à 18h30 à Paris, suite à l'attaque sanglante ciblant des camarades Kurdes, faisant 3 morts et 4 blessés graves. Nous appelons à rejoindre massivement la manifestation appelée par le CDK-F ce samedi 24 décembre à 12H Place de la République à Paris. Tout notre soutien aux camarades Kurdes, Un coup porté contre l'un-e d'entre nous est un coup porté contre nous tous.toutes ! La solidarité sera toujours notre arme ! Le Secrétariat International de la CNT | 2022 | 2022-12-27T17:10:55Z |
| DTIC ADA392349: Action of the p53 Effector, p21, on its Targets: Cyclin-cdk and PCNA | Cy or RXL motifs have been previously shown to be cyclin binding motifs found in a wide range of cyclin-cdk interacting proteins. For both cyclin A/cdk2 and cyclin E/cdk2, the presence of a Cy motif decreased the Km(sup peptide! 75 to 120-fold while the kcat remained unchanged. Changes in the length of the linker between the Cy motif and the phosphoacceptor serine suggest that both sites are engaged simultaneously to the cyclin and the cdk, respectively. PS100, a peptide containing a Cy motif, acts as a competitive inhibitor of cyclin/cdk complexes with a 15-fold lower Ki for cyclin E/cdk2 than for cyclin A/cdk2. These results provide kinetic proof that a Cy motif located at a minimal distance from the SPXK is essential for optimal phosphorylation by cdks and suggest that small chemicals that mimic the Cy motif would be specific inhibitors of substrate recognition by cyclin-dependent kinases. In addition, a detailed mutagenesis approach to define what sequence serves as a Cy motif reve; | 2000 | 2018-05-03T14:38:06Z |
| CDK-120 | | | 2021-04-17T01:59:16Z |
| FReeKS014: Make Rave Not Hate Stays Drum'n' Bass | Make Rave, not Hate stays Drum'n'Bass! In this show our Radio DJ Robb plays an one hour Drum'n'Bass-Set – strictly Open Music found on the Netaudio Platform ccMixter . In addition we also have some radio information for our German and Rhein-Neckar based listeners. Playlist Apoxode – Escape from Mars 180 Blake – Jack Frost Analog By Nature – Don't go (RumbleStep Mix) Analog By Nature – If God Was Sleeping (cdk Mix) Analog By Nature – Loveshadow - You Made It Up ^ (cdk Mix) Abstract Audio – Dorst Blake – I know your voice spinningmerkaba – Reusenoise (DNB Mix) Abstract Audio – CCMixter (We are not evil) Scott Altham – I got the rhymes (Electric Fish Mix) Alex – Dancing Like A Maniac bangcorrupt – Freedom Analog By Nature – Time (cdk Give Me Some Dubstep Extended Mix) Abstract Audio – Dinosaur Bones Apoxode – Crystal Clear 180 | 2020 | 2020-07-22T21:25:21Z |
| Re-thinking cell cycle regulators: the cross-talk with metabolism. | This article is from Frontiers in Oncology , volume 3 . Abstract Analysis of genetically engineered mice deficient in cell cycle regulators, including E2F1, cdk4, and pRB, showed that the major phenotypes are metabolic perturbations. These key cell cycle regulators contribute to lipid synthesis, glucose production, insulin secretion, and glycolytic metabolism. It has been shown that deregulation of these pathways can lead to metabolic perturbations and related metabolic diseases, such as obesity and type II diabetes. The cyclin–cdk–Rb–E2F1 pathway regulates adipogenesis in addition to its well-described roles in cell cycle regulation and cancer. It was also shown that E2F1 directly participates in the regulation of pancreatic growth and function. Similarly, cyclin D3, cdk4, and cdk9 are also adipogenic factors with strong effects on whole organism metabolism. These examples support the emerging notion that cell cycle regulatory proteins also modulate metabolic processes. These ce; | 2013 | 2014-10-28T16:47:52Z |
| github.com-TinkoffCreditSystems-taiga-ui_-_2021-01-15_19-09-44 | Angular UI Kit and components library for awesome people Taiga UI Website • Documentation • CDK Wiki • Core team Taiga UI is fully-treeshakable Angular UI Kit consisting of multiple base libraries and several add-ons. It is based on ng-polymorpheus dynamic content approach and uses Web APIs for Angular for required browser APIs. Why Taiga UI 🧩 Modular and fully-treeshakable. We harnessed the power of Secondary Entry Points mechanism. You can import even just one entity from our library and be sure that there is no redundant code in your bundle 🧙 Agnostic . Our components are very flexible and are ready for any use case. But we take care of basic UX aspects to let you focus on your project features 🦋 Customizable . We use CSS custom properties for all our styling and provide easy methods to customize all UI components 🛠 Well engineered . We are not afraid of DI, all our components use OnPush and the whole project is developed with strict TypeScript mode 📦 It's big! ; | 2021 | 2021-01-16T03:16:22Z |
| Anti-Cancer Effect of IN-2001 in T47D Human Breast Cancer. | This article is from Biomolecules & Therapeutics , volume 20 . Abstract Histone deacetylases (HDACs) are enzymes involved in the remodelling of chromatin, and have a key role in the epigenetic regulation of gene expression. Histone deacetylase (HDAC) inhibitors are emerging as an exciting new class of potential anti-cancer agents. In recent years, a number of structurally diverse HDAC inhibitors have been identified and these HDAC inhibitors induce growth arrest, differentiation and/or apoptosis of cancer cells in vitro and in vivo. However, the underlying molecular mechanisms remain unclear. This study aimed at investigating the anti-tumor activity of various HDAC inhibitors, IN-2001, using T47D human breast cancer cells. Moreover, the possible mechanism by which HDAC inhibitors exhibit anti-tumor activity was also explored. In estrogen receptor positive T47D cells, IN-2001, HDAC inhibitor showed anti-proliferative effects in dose-and time-dependent manner. In T47D human breast cancer; | 2011 | 2014-10-24T20:14:53Z |
| Het bericht ‘CdK haalt ongemeen fel uit naar de NAM’ | This document is issued on date 2015-05-27. | 2015 | 2018-03-14T20:02:09Z |