| Title | Description | Published | Added |
| DTIC ADA412793: Chemotherapy of Late Stage Breast Cancer Targeted Towards Cell Cycle Regulatory Components | Our original goal was to target cell cycle regulatory components as a potential therapy for breast cancer. The target p16 is a tumor suppressor and a CDK inhibitor and is inactivated by gene methylation. The drug 5-aza-2'deoxycytidine (5-Aza-CdR), an inhibitor of DNA methylation, is targeted for reexpression of a repressed p16 in late stage breast cancer patients. Re-activation of the p16 gene in cells in which the gene is methylated will restore normal growth control and be efficacious in treatment of breast cancer. A mouse model for the action of the drug was developed and used to test the efficacy of the drug. | 2002 | 2018-05-12T16:53:07Z |
| Redacting PII data at The Very Group with Amazon Comprehend | This three-part series demonstrates how to use graph neural networks (GNNs) and Amazon Neptune to generate movie recommendations using the IMDb and Box Office Mojo Movies/TV/OTT licensable data package, which provides a wide range of entertainment metadata, including over 1 billion user ratings; credits for more than 11 million cast and crew members; 9 million movie, TV, and entertainment titles; and global box office reporting data from more than 60 countries. Many AWS media and entertainment customers license IMDb data through AWS Data Exchange to improve content discovery and increase customer engagement and retention. The following diagram illustrates the complete architecture implemented as part of this series. To demonstrate the OOC search functionality with a simple example, we split the IMDb knowledge graph into customer-catalog and out-of-customer-catalog. We mark the titles that contain \"Toy Story\" as an out-of-customer catalog resource and the rest of the IMDb knowledge gr; | 2023 | 2023-01-29T23:46:41Z |
| DTIC ADA360338: Development and Use of Novel Tools to Directly Screen for Substrates of Cyclin Dependent Kinases | Cell division is a central and primary biological function. Many problems in biology and medicine center around cell division, but without a knowledge of the mechanism by which division is controlled, these problems are difficult to attack. The major transitions of the cell cycle are is controlled by a protein called a cyclin dependent kinase, or Cdk. The cell cycles of both yeast and human cells are controlled by a Cdk. Using the yeast two hybrid system I have isolated many novel Cdk interacting proteins in yeast, and these may be instrumental in controlling cell cycle progression. I have also isolate two exciting proteins which can only interact with a substrate trapping mutant of a yeast Cdk. These may be Cdk new substrates. I have also used the genomic technology of Gene Chips, to define the complete set of cell cycle regulated genes in yeast, and to characterize their controlling promoter elements. These two projects have yielded novel and exciting results, of interest to both the; | 1998 | 2018-04-22T05:07:32Z |
| Bob Baker Volkswagen v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2018-09-16T22:44:00Z |
| ＰＨＯＮＫ ＦＲＩＤＡＹＳ | iNFMS - The Don Chronicles pt.1 | PHONK FRIDAY SEASON 3 | Episode 1 --------------------------------------------------------------- Produced by iNFMS | https://infms495.bandcamp.com/ Video Edit by iNFMS chapter 3: 𝖙𝖍𝖊 𝖉𝖔𝖓 𝖈𝖍𝖗𝖔𝖓𝖎𝖈𝖑𝖊𝖘 - [00:20] MAKE SOME ENDZ [03:14] SHE DONT EVEN SMOKE [06:23] ADRENOCHROME [09:48] ADRENOCHROME PT 2 [11:49] 200 THOUSAND ON MY WRIST [15:07] $CREWED UP [17:34] SMOKIN OUT - -special thanks: LORDKADO, STVSHBOI, PXSSXSSXD, BADRADIO and ANALOG BY NATURE - -audio drip: https://soundcloud.com/iaminfms/the-don-chronicles-vol-1 - https://www.analogbynature.tv https://www.badradio.nz Twitter - twitter.com/official_iNFMS Twitch - twitch.tv/analogbynature DLive - https://dlive.tv/cdk - Official Spotify Playlist: https://spoti.fi/2V5Jzqr Join : https://bit.ly/2UIIw08 ▶▶ATTENTION ARTISTS AND PRODUCERS▶▶ ----Submissions: http://bitSubmit.net/21 ---100% Free Music Distribution on spotify , itunes , and more http://www.amuse.io?utm_source=RC ▶▶Co; | 2020 | 2024-02-12T06:19:34Z |
| github.com-angular-components_-_2021-09-03_22-25-54 | Component infrastructure and Material Design components for Angular Official components for Angular The Angular team builds and maintains both common UI components and tools to help you build yourown custom components. The team maintains several npm packages. | Package | Description | Docs || ------------------------- | ----------------------------------------------------------------------------------- | ---------------- || @angular/cdk | Library that helps you author custom UI components with common interaction patterns | Docs || @angular/material | Material Design UI components for Angular applications | Docs || @angular/google-maps | Angular components built on top of the Google Maps JavaScript API | Docs || @angular/youtube-player | Angular component built on top of the YouTube Player API | Docs | Quick links Documentation, demos, and guides | Frequently Asked Questions | Community Google group | Contributing | StackBlitz Template Getting started See our Getting Started Guide if yo; | 2021 | 2021-09-03T22:51:37Z |
| Berlioz: Symphonie Fantastique / Symphony No.5 / Prometheus Overture | Tracklist: 1. Die Geschöpfe des Prometheus Op.43 - Overture - Ludwig van Beethoven 2. Symphony No.5 in Bb major D485 - I. Allegro - Franz Schubert 3. Symphony No.5 in Bb major D485 - II. Andante con moto - Franz Schubert 4. Symphony No.5 in Bb major D485 - III. Menuetto: Allegro molto - Trio - Franz Schubert 5. Symphony No.5 in Bb major D485 - IV. Allegro vivace - Franz Schubert 6. Symphonie Fantastique Op.14 - I. Rêveries. Passions (Largo - Allegro agitato ed appassionato assai) - Hector Berlioz 7. Symphonie Fantastique Op.14 - II. Un bal (Valse: Allegro non troppo) - Hector Berlioz 8. Symphonie Fantastique Op.14 - III. Scène aux champs (Adagio) - Hector Berlioz 9. Symphonie Fantastique Op.14 - IV. Marche au supplice (Allegretto non troppo) - Hector Berlioz 10. Symphonie Fantastique Op.14 - V. Songe d'une nuit du Sabbat (Larghetto - Allegro) - Ronde du Sabbat (Poco meno mosso) - Hector Berlioz | 2000 | 2024-03-29T01:08:00Z |
| odp-cdk-example | This is an archive of the project's publicly available source code and (where available) wiki repositories in bare git format, as well as related issues, pull requests and similar data from Github in JSON format, created on 2025-03-06. Project 'odp-cdk-example' from agency 'GSA', organization 'GSA'. Original project description: A serverless demonstration of the AWS CDK using Lambda, API Gateway, and Amazon S3 :rocket: | 2025 | 2025-03-12T18:53:16Z |
| DTIC ADA411262: Targeting the AP-1 Transcription Factor for the Treatment of Breast Cancer | The AP-l transcription factor is a central component of many signal transduction pathways. We have shown that blocking AP-l by over-expressing a dominant negative form - of cJun (cjun-DN, Tam67) inhibits breast cancer cell growth. We hypothesize that- inhibition of AP-l blocks the cell cycle, reverses TAM-resistance of breast cancer cells, and suppression of AP-l in vivo causes regression of existing breast tumors. In the present study, we demonstrated that TAM67 inhibits breast cancer growth both in vitro and in vivo. We determined the mechanism by which AP-l blockade inhibits breast cancer growth. Our studies suggested that TAM67 inhibits breast cancer growth predominantly by inducing CDK inhibitors (such as P27), suppressing GI cyclins expression and reducing CDKs activity, thus inducing a cell cycle block. We also showed that TAM67 induces apoptosis in serum-free condition in breast cancer cells. We are currently investigating the molecular mechanism by which TAM67 causes a cell cy; | 2002 | 2018-05-12T03:54:47Z |
| DTIC ADA369304: Role of cdc25 Phosphatases in Cellular Immortalization. | The goal of this proposal is to study the potential role of tyrosine phosphorylation-dependent checkpoint and especially the cdc25 phosphatase family of cyclin dependent kinase (CDK) activators in cellular immortalization. We have shown that cdc25 phosphatases did in fact extend the normal mammary epithelial cells life span, but do not immortalize them. The effect was most prominent with cdc25A and cdc25B phosphatases. Cdc25C phosphatase' had less effect on HMEC life span. Experiments with catalytically inactive cdc25A mutant show that phosphatase activity of cdc25A is essential for the life span extension. Our experiments shows that telomerase is not activated by cdc25A expression in normal human cells, suggesting that cdc25 most likely affect Ml. but not M2 checkpoints. | 1999 | 2018-04-25T22:23:31Z |
| Identification of Genes Interacting with rnt-1 Through Large-Scale RNAi Screening in Caenorhabditis elegans. | This article is from G3: Genes|Genomes|Genetics , volume 3 . Abstract Although many critical roles of the RUNX family proteins have already been identified, little attention has been given to how these proteins interact with other factors. Elucidating RUNX protein interactions will help extend our understanding of their roles in normal development and tumorigenesis. In this study, we performed large-scale RNAi screening to identify genes that genetically interact with rnt-1, the sole homolog of RUNX protein in the nematode Caenorhabditis elegans. To this end, we took advantage of the fact that C. elegans can survive a severe loss of RNT-1 function with only mild phenotypes, and we looked for genes that caused a synthetic phenotype in the rnt-1 mutant background. We identified seven genes, three of which (cdk-8, cic-1, and sur-2) are involved in transcription, two of which (pgp-2 and cct-5) are involved in stress response, and two of which (D2045.7 and W09D10.4) are involved in signalin; | 2013 | 2014-10-28T00:42:20Z |
| Mad Money : CNBC : November 7, 2018 6:00pm-7:00pm EST | Colorful financial analyst Jim Cramer offers his insights into the market. | 2018 | 2018-11-07T23:00:00Z |
| Boleros | Tracklist: 1. El Reloj/Perfidia/Mira Gue Eres Linda/Maria Elena/Aquellos Ojos Verdes/El Reloj/Te Quiero Dijiste/La Barca/Historia De Un Amor/El Reloj/Siboney/Sabor A Mi/Quiereme Mucho/El Reloj/Amapola/Angelitos Negros/Solamente Un Vez/Besame Mucho/El Reloj/Vamos A La Cama/La Conga 2. Me Lo Dijo Adela/Mi Vaca Lechera/Maria Christina Me Quiere Governar/Tequila/La Conga/Salud, Dinero Y Amor/Cielito Lindo/La Pachanga/La Gallina Papanatas/La Conga/La Bamba/La Raspa/La Cucaracha/La Conga/Se Va El Caiman/Todos Queremos Mas/Baio De Ana/La Conga/Vamos A La Cama | 1988 | 2024-07-11T07:14:09Z |
| Corridos del Pueblo Con Banda | Tracklist: 1. Carga ladeada - Paulino Vargas 2. El michoacano - Federico Villa 3. El tamal - Joel Elizalde 4. Terrible cuerno de chivo - Los Tahures 5. El contrabando de Nogales - Lalo Elizalde 6. Los dos hermanos - Federico Villa 7. Las parcelas de Mendoza - Joel Elizalde 8. El cabo de Michoacâan - Los Tahures 9. El gallo de San Juan - Lalo Elizalde 10. Sucediâo en la barranca - Federico Villa 11. El moro y la mora - Joel Elizalde 12. La bronco negra - Los Tahures | 2002 | 2025-03-31T06:01:33Z |
| eBookMan.cdk | eBookman Content Developer Kit (CDK) multiple releases The CDK has not yet been tested. Compiled by members of the Bookman Archive site . | | 2022-01-13T11:19:46Z |
| Mahatma Gandhi | | 2012 | 2024-01-04T12:38:14Z |
| Death is a silent room | | 1965 | 2023-08-29T22:36:40Z |
| github.com-aws-aws-cdk_-_2022-09-21_02-53-56 | The AWS Cloud Development Kit is a framework for defining cloud infrastructure in code AWS Cloud Development Kit (AWS CDK) The AWS Cloud Development Kit (AWS CDK) is an open-source software developmentframework to define cloud infrastructure in code and provision it through AWS CloudFormation. It offers a high-level object-oriented abstraction to define AWS resources imperatively usingthe power of modern programming languages. Using the CDK’s library ofinfrastructure constructs, you can easily encapsulate AWS best practices in yourinfrastructure definition and share it without worrying about boilerplate logic. The CDK is available in the following languages: JavaScript, TypeScript ( Node.js ≥ 14.15.0 ) We recommend using a version in Active LTS Python ( Python ≥ 3.6 ) Java ( Java ≥ 8 and Maven ≥ 3.5.4 ) .NET ( .NET Core ≥ 3.1 ) Go ( Go ≥ 1.16.4 ) Third-party Language Deprecation: language version is only supported until its EOL (End Of Life) shared by the vendor or commun; | 2022 | 2022-09-21T05:05:30Z |
| [CDK 014] Assault | An assault on the senses? An assault on modern society? An assault on South Arctic (I and II)? An assault on old video gaming equipment? Whatever the Assault, it’s gonna assault your ears – in the best way possible! Goatslacker is a Floridian chiptuner who also uses the occasional keyboards ‘n’ drums for his music. He has a GSOH, likes walks in the parks and cinema and WLTM a person with similar interests in phat basslines and tight drums. | 2008 | 2019-12-06T22:45:14Z |
| Concentration-dependent effects of narciclasine on cell cycle progression in Arabidopsis root tips. | This article is from BMC Plant Biology , volume 11 . Abstract Background: Narciclasine (NCS) is an Amaryllidaceae alkaloid isolated from Narcissus tazetta bulbs. NCS has inhibitory effects on a broad range of biological activities and thus has various potential practical applications. Here we examine how NCS represses plant root growth. Results: Results showed that the inhibition of NCS on cell division in Arabidopsis root tips and its effects on cell differentiation are concentration-dependent; at low concentrations (0.5 and 1.0 μM) NCS preferentially targets mitotic cell cycle specific/cyclin complexes, whereas at high concentration (5.0 μM) the NCS-stimulated accumulation of Kip-related proteins (KRP1 and RP2) affects the CDK complexes with a role at both G1/S and G2/M phases. Conclusions: Our findings suggest that NCS modulates the coordination between cell division and differentiation in Arabidopsis root tips and hence affects the postembryonic development of Arabidopsis seedlin; | 2011 | 2014-10-28T22:30:05Z |
| Cyclic strain upregulates VEGF and attenuates proliferation of vascular smooth muscle cells. | This article is from Vascular Cell , volume 3 . Abstract Objective: Vascular smooth muscle cell (VSMC) hypertrophy and proliferation occur in response to strain-induced local and systemic inflammatory cytokines and growth factors which may contribute to hypertension, atherosclerosis, and restenosis. We hypothesize VSMC strain, modeling normotensive arterial pressure waveforms in vitro, results in attenuated proliferative and increased hypertrophic responses 48 hrs post-strain. Methods: Using Flexcell Bioflex Systems we determined the morphological, hyperplastic and hypertrophic responses of non-strained and biomechanically strained cultured rat A7R5 VSMC. We measured secretion of nitric oxide, key cytokine/growth factors and intracellular mediators involved in VSMC proliferation via fluorescence spectroscopy and protein microarrays. We also investigated the potential roles of VEGF on VSMC strain-induced proliferation. Results: Protein microarrays revealed significant increases in VEGF ; | 2011 | 2014-10-27T22:12:00Z |
| Ayer, Hoy y Siempre, Vol. 1 | Tracklist: 1. La Canelera 2. Sin Rencor 3. Morenita Encantadora 4. Rosalito 5. La Mala Sombra 6. Cruz de Madera 7. Se Que No Eres Libre 8. Morenita Querida 9. Sin Rivales 10. Ya No Sufras 11. Seras Para Mi 12. Que Nos Perdone Dios 13. Porque La Quiero 14. Porque Probaste El Fruto 15. No Soy Feliz 16. Tus Quince Años 17. Tu Eres 18. Traicion Por Amor 19. Mil Promesas 20. Pilares de Cristal | 2002 | 2025-04-24T00:24:25Z |
| Fire-Tongue | | 1922 | 2023-07-25T01:03:48Z |
| DTIC ADA415783: Regulated Transformation of Mammary Epithelial Cells by Transforming Growth Factor Beta 1 | We report that MMTV-DNIIR female mice have accelerated mammary gland differentiation during early pregnancy with impaired development during late pregnancy and lactation followed by delayed post-lactational involution. Mammary tumors, mostly carcinoma in situ, developed spontaneously in the MMTV-DNIIR mice with a long median latency (27.5 months). Invading carcinoma cells in MMTV-DNIIR animals showed loss of DNIIR transgene expression as determined by in situ hybridization. The data indicate that signaling from endogenous TGF-Betas not only plays an important role in normal mammary gland physiology but also can also suppress the early stage of tumor formation and contribute to tumor invasion once carcinomas have developed. The ability of the TGF-beta signaling pathways to inhibit proliferation of many epithelial cells while stimulating proliferation fibroblasts remains a conundrum. We found that the absence of RhoA and p160(ROCK) activity in fibroblastic NIH3T3 cells and its presence i; | 2003 | 2018-05-13T18:21:14Z |
| The fortunate islands, a Pacific interlude;: An account of the pleasant lands and people in the United States' Trust Territory of the Pacific | | 1948 | 2024-01-04T16:01:13Z |
| github.com-sindresorhus-awesome_-_2023-10-26_11-42-32 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app One Task Stop procrastination and get stuff done by focusing on one task at a time My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. API to get search engine results with ease. API to get search engine results with ease. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Develop; | 2023 | 2023-10-26T13:33:54Z |
| Are phylogenetic trees suitable for chemogenomics analyses of bioactivity data sets: the importance of shared active compounds and choosing a suitable data embedding method, as exemplified on Kinases. | This article is from Journal of Cheminformatics , volume 5 . Abstract Background: ‘Phylogenetic trees’ are commonly used for the analysis of chemogenomics datasets and to relate protein targets to each other, based on the (shared) bioactivities of their ligands. However, no real assessment as to the suitability of this representation has been performed yet in this area. We aimed to address this shortcoming in the current work, as exemplified by a kinase data set, given the importance of kinases in many diseases as well as the availability of large-scale datasets for analysis. In this work, we analyzed a dataset comprising 157 compounds, which have been tested at concentrations of 1 μM and 10 μM against a panel of 225 human protein kinases in full-matrix experiments, aiming to explain kinase promiscuity and selectivity against inhibitors. Compounds were described by chemical features, which were used to represent kinases (i.e. each kinase had an active set of features and an ina; | 2013 | 2014-10-28T15:40:11Z |
| Cierra la Puerta | Tracklist: 1. Cierra la Puerta 2. Una Copa Mas 3. Paloma Begra 4. Ahora Por Idea 5. Mi Sufrir 6. Anselma 7. Mi Dia de Suerte 8. Imelda 9. Que Dolor 10. El Ronquidito | 2001 | 2024-07-11T12:56:48Z |
| Differential roles of Smad2 and Smad3 in the regulation of TGF-?1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1. | This article is from Molecular Cancer , volume 10 . Abstract Background: Progression of pancreatic ductal adenocarcinoma (PDAC) is largely the result of genetic and/or epigenetic alterations in the transforming growth factor-beta (TGF-β)/Smad signalling pathway, eventually resulting in loss of TGF-β-mediated growth arrest and an increase in cellular migration, invasion, and metastasis. These cellular responses to TGF-β are mediated solely or partially through the canonical Smad signalling pathway which commences with activation of receptor-regulated Smads (R-Smads) Smad2 and Smad3 by the TGF-β type I receptor. However, little is known on the relative contribution of each R-Smad, the possible existence of functional antagonism, or the crosstalk with other signalling pathways in the control of TGF-β1-induced growth inhibition and cell migration. Using genetic and pharmacologic approaches we have inhibited in PDAC cells endogenous Smad2 and Smad3, as well as a potential regulator, th; | 2011 | 2014-10-29T05:01:17Z |
| Rthk deleted videos from youtube part 5 | 2008新季度電視節目巡禮 - 逢星期一至五晚七點無綫電視翡翠台-LCCfsS1nXu4.mkv 2008新季度電視節目巡禮 - 週末週日晚七點亞洲電視本港台--R5EdBfYJLM.mp4 2008立法會選舉．嘉賓呼籲-2NHsh29sOCU.mkv 2008立法會選舉．歌星呼籲(一)-ycoW4_qGngE.mkv 2008立法會選舉．歌星呼籲(二)-F6PRDGrIUko.mkv 2009-06-25 議事論事 - 免費電視牌照中期檢討-C9o2RCsPwIs.mp4 2009-06-25 議事論事 - 議會新人王梁美芬-N9wooVO8lmc.mkv 2009-06-25 議事論事 -李鵬飛訪問劉銳紹-KuDMVOaT2mc.mp4 2009-09-04 The Pulse - web 2.0 technology-QEkzNt9wV9w.mp4 2010-6-10 議事論事 - 議事堂邊鶴-v0K6pzFsPYs.mkv 2010-6-5 頭條新聞 - 一錨擊起千重浪-f-l5Hm6gCYM.ia.mp4 2010-6-5 頭條新聞 - 一錨擊起千重浪-f-l5Hm6gCYM.mp4 2010-6-5 頭條新聞 - 動筆動（一木）- 玩鋪勁-u_ETGYM9FZ8.mkv 24_03_2009重點新聞：牛頭角下邨即將清拆-UyX_dAQAazA.ia.mp4 24_03_2009重點新聞：牛頭角下邨即將; | | 2022-09-10T07:23:23Z |
| [CDK 024] Dextroid | Dexter is a Game Boy musician straight outta Southampton, and he’s decided to grace CDKr with his debut album – a pretty intense 15 tracks of musical fun! He’s definitely a chipmusician going places, don’t be surprised to see this guy making it MASSEEV in chiptune, fo sho. | 2008 | 2019-12-07T00:28:52Z |
| Capillary Gas Chromatography in Essential Oil Analysis | | 1987 | 2023-12-22T14:00:41Z |
| Check-List of Birds of the World. Volume IV | | 1940 | 2023-07-29T08:55:41Z |
| The Early theory of equations : on their nature and constitution : translations of three treatises | 218 p. ; 23 cm // On the recognition of equations / by François Viète -- A new discovery in algebra / by Albert Girard -- On the nature and constitution of equations / by Florimond de Beaune | 1986 | 2023-12-22T11:17:45Z |
| Old Vincennes: The history of a famous old town and its glorious past | | 1962 | 2023-12-23T20:12:56Z |
| github.com-sindresorhus-awesome_-_2023-05-14_15-35-37 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app Today Quickly view your schedule in the macOS menu bar My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Build Scalable Feeds & Chat Applications with Powerful APIs and Front End Components Build Scalable Feeds & Chat Applications with Powerful APIs and Front End Components Paperwork that makes the data work. Easy APIs for paperwork. PDF generation, e-signature and embeddable no-code webforms. The easiest way to build paperwork automation into your product. Paperwork that makes the data work. E; | 2023 | 2023-05-14T17:50:28Z |
| github.com-sindresorhus-awesome_-_2023-10-24_23-57-20 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app One Task Stop procrastination and get stuff done by focusing on one task at a time My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. API to get search engine results with ease. API to get search engine results with ease. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Develop; | 2023 | 2023-10-25T11:07:00Z |
| github.com-serverless-stack-serverless-stack_-_2022-02-07_09-07-40 | 💥 SST makes it easy to build serverless apps. Set breakpoints and test your functions locally. https://serverless-stack.com Serverless Stack (SST) is a framework that makes it easy to build serverless apps. It's an extension of AWS CDK and it features: A Live Lambda Development environment Support for setting breakpoints and debugging in VS Code Support for deploying to multiple environments and regions Higher-level constructs designed specifically for serverless apps Zero-config support for JS and TS (using esbuild ), Go, Python, C#, and F# Quick Start Create your first SST app. ```bash Create your app $ npx create-serverless-stack@latest my-sst-app$ cd my-sst-app Start Live Lambda Development $ npx sst start Deploy to prod $ npx sst deploy --stage prod``` Documentation SST docs SST examples Public roadmap Feature requests Contributing to SST Follow us on Twitter and subscribe to our newsletter for updates. About SST We think SST can make it dramatically easier to build serverless ; | 2022 | 2022-02-07T09:45:28Z |
| The Courtesy Book | | 1927 | 2024-06-27T03:16:26Z |
| EP 12: Kelsey Smith - Abducted In Broad Daylight | Kelsey Smith was just 18 years old when she was abducted from a Target parking lot in Overland Park, Kansas in June 2007. Finding her would take a battle with a cellular phone company and heartbreaking surveillance video from Target, that shows that no one is ever really safe, even if you're running a simple errand in broad daylight. A special thank you to Kelsey's mom, Missey Smith, for speaking with me for this episode. To learn more about the Kelsey Smith Foundation and the Kelsey Smith Act, please visit kelseysarmy.org. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode: - Summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/cdk/13112 - Like Music (cdk Mix) by c; | 2017 | 2023-07-08T12:40:23Z |
| Commissioner Sullivan message to Clatsop County April 22 | | 2020 | 2022-10-14T13:47:04Z |
| github.com-hashicorp-terraform-cdk_-_2022-10-05_02-24-10 | Define infrastructure resources using programming constructs and provision them using HashiCorp Terraform CDK for Terraform Cloud Development Kit for Terraform (CDKTF) allows you to use familiarprogramming languages to define cloud infrastructure and provision it throughHashiCorp Terraform. This gives you access to the entire Terraform ecosystem without learning HashiCorp Configuration Language (HCL) and lets you leverage the power of your existing toolchain for testing, dependency management, etc. We currently support TypeScript, Python, Java, C#, and Go. CDKTF includes two packages: cdktf-cli - A CLI that allows users to run commands to initialize, import, and synthesize CDK for Terraform applications. cdktf - A library for defining Terraform resources using programming constructs. Get Started Choose a language: TypeScript Python Java C# Go Hands-on: Try the tutorials in the CDK for Terraform collection on HashiCorp Learn. Documentation Refer to the CDKTF documentation for more detai; | 2022 | 2022-10-05T12:18:54Z |
| github.com-angular-components_-_2021-09-01_20-08-54 | Component infrastructure and Material Design components for Angular Official components for Angular The Angular team builds and maintains both common UI components and tools to help you build yourown custom components. The team maintains several npm packages. | Package | Description | Docs || ------------------------- | ----------------------------------------------------------------------------------- | ---------------- || @angular/cdk | Library that helps you author custom UI components with common interaction patterns | Docs || @angular/material | Material Design UI components for Angular applications | Docs || @angular/google-maps | Angular components built on top of the Google Maps JavaScript API | Docs || @angular/youtube-player | Angular component built on top of the YouTube Player API | Docs | Quick links Documentation, demos, and guides | Frequently Asked Questions | Community Google group | Contributing | StackBlitz Template Getting started See our Getting Started Guide if yo; | 2021 | 2021-09-01T21:39:39Z |
| The role of ?-adrenergic receptor signaling in the proliferation of hemangioma-derived endothelial cells. | This article is from Cell Division , volume 8 . Abstract Background: Infantile hemangioma (IH) is a benign vascular neoplasm that arises from the abnormal proliferation of endothelial cells and enhanced angiogenesis. Recently, propranolol has been found to be effective in the management of IH, suggesting that β-adrenergic receptors (β-ARs) may play an important role in the pathogenesis of IH. Results: In the present study, we investigated the β-adrenergic signaling that is associated with hemangioma-derived endothelial cell (HemEC) proliferation. The results showed that both β1- and β2-ARs were expressed in HemECs. Stimulation of the β-ARs by isoprenaline induced cell proliferation and elevation of second messenger cAMP levels. The proliferation-promoting action of isoprenaline was abolished by a β1-selective antagonist and was more effectively abolished by a β2-selective antagonist; the mechanism for the action of the antagonists was a G0/G1 phase cell cycle arrest which was a; | 2013 | 2014-10-29T13:12:50Z |
| Graphs with Diameter $n-e$ Minimizing the Spectral Radius | The spectral radius $\rho(G)$ of a graph $G$ is the largest eigenvalue of its adjacency matrix $A(G)$. For a fixed integer $e\ge 1$, let $G^{min}_{n,n-e}$ be a graph with minimal spectral radius among all connected graphs on $n$ vertices with diameter $n-e$. Let $P_{n_1,n_2,...,n_t,p}^{m_1,m_2,...,m_t}$ be a tree obtained from a path of $p$ vertices ($0 \sim 1 \sim 2 \sim ... \sim (p-1)$) by linking one pendant path $P_{n_i}$ at $m_i$ for each $i\in\{1,2,...,t\}$. For $e=1,2,3,4,5$, $G^{min}_{n,n-e}$ were determined in the literature. Cioab\v{a}-van Dam-Koolen-Lee \cite{CDK} conjectured for fixed $e\geq 6$, $G^{min}_{n,n-e}$ is in the family ${\cal P}_{n,e}=\{P_{2,1,...1,2,n-e+1}^{2,m_2,...,m_{e-4},n-e-2}\mid 2 | 2011 | 2013-09-23T15:53:26Z |
| Applications of the InChI in cheminformatics with the CDK and Bioclipse. | This article is from Journal of Cheminformatics , volume 5 . Abstract Background: The InChI algorithms are written in C++ and not available as Java library. Integration into software written in Java therefore requires a bridge between C and Java libraries, provided by the Java Native Interface (JNI) technology. Results: We here describe how the InChI library is used in the Bioclipse workbench and the Chemistry Development Kit (CDK) cheminformatics library. To make this possible, a JNI bridge to the InChI library was developed, JNI-InChI, allowing Java software to access the InChI algorithms. By using this bridge, the CDK project packages the InChI binaries in a module and offers easy access from Java using the CDK API. The Bioclipse project packages and offers InChI as a dynamic OSGi bundle that can easily be used by any OSGi-compliant software, in addition to the regular Java Archive and Maven bundles. Bioclipse itself uses the InChI as a key component and calculates it on the fly whe; | 2013 | 2014-10-27T02:14:25Z |
| 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27. | This article is from Cell Death & Disease , volume 5 . Abstract The control of glucose metabolism and the cell cycle must be coordinated in order to guarantee sufficient ATP and anabolic substrates at distinct phases of the cell cycle. The family of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFKFB1-4) are well established regulators of glucose metabolism via their synthesis of fructose-2,6-bisphosphate (F2,6BP), a potent allosteric activator of 6-phosphofructo-1-kinase (Pfk-1). PFKFB3 is overexpressed in human cancers, regulated by HIF-1α, Akt and PTEN, and required for the survival and growth of multiple cancer types. Although most functional studies of the role of PFKFB3 in cancer progression have invoked its well-recognized function in the regulation of glycolysis, recent observations have established that PFKFB3 also traffics to the nucleus and that its product, F2,6BP, activates cyclin-dependent kinases (Cdks). In particular, F2,6BP stimulates the Cdk-mediated phospho; | 2014 | 2014-10-08T05:47:42Z |
| Faulkner v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-10-12T07:17:13Z |
| A systematic screen reveals new elements acting at the G2/M cell cycle control. | This article is from Genome Biology , volume 13 . Abstract Background: The major cell cycle control acting at the G2 to mitosis transition is triggered in all eukaryotes by cyclin-dependent kinases (CDKs). In the fission yeast Schizosaccharomyces pombe the activation of the G2/M CDK is regulated primarily by dephosphorylation of the conserved residue Tyr15 in response to the stress-nutritional response and cell geometry sensing pathways. To obtain a more complete view of the G2/M control we have screened systematically for gene deletions that advance cells prematurely into mitosis. Results: A screen of 82% of fission yeast non-essential genes, comprising approximately 3,000 gene deletion mutants, identified 18 genes that act negatively at mitotic entry, 7 of which have not been previously described as cell cycle regulators. Eleven of the 18 genes function through the stress response and cell geometry sensing pathways, both of which act through CDK Tyr15 phosphorylation, and 4 of the re; | 2012 | 2014-10-24T16:07:32Z |
| Germinal | | 1951 | 2023-07-25T01:30:34Z |