| Author | Title | Print-Published | Type | DOI@Sci-hub |
| CDK | | reference-entry | 10.1007/springerreference_92996 |
| Functions of CDK/cyclin Complexes in Endoreplication Regulation by the CDK Inhibitor SIAMESE | | dissertation | 10.31390/gradschool_dissertations.5173 |
| CDK | | reference-entry | 10.1007/springerreference_37256 |
| Pandit, J. | Novel CDK-5 inhibitors - crystal structure of inhibitor EFQ with CDK-2 | 2009/9/8 | dataset | 10.2210/pdb3igg/pdb |
| Pandit, J. | Novel CDK-5 inhibitors - crystal structure of inhibitor EFP with CDK-2 | 2009/9/8 | dataset | 10.2210/pdb3ig7/pdb |
| Figure 4—figure supplement 1. CDK–phosphorylation of ORC intrinsically inhibits helicase loading. | | component | 10.7554/elife.33309.013 |
| CDK Inhibitor R547 | | reference-entry | 10.32388/iap5sl |
| Willighagen, Egon | 10000 CDK commits! | | posted-content | 10.59350/w1hpp-ks316 |
| Willighagen, Egon | CDK Literature #3 | | posted-content | 10.59350/rkkty-a3w29 |
| Willighagen, Egon | CDK News | | posted-content | 10.59350/xf9bq-44218 |
| Cermin Dunia Kedokteran | | journal | 10.55175/cdk |
| CDK | | book-chapter | 10.1007/3-540-30683-8_274 |
| Willighagen, Egon | CDK Literature #4 | | posted-content | 10.59350/es4e7-esh15 |
| CDK Inhibitor AT7519 | | reference-entry | 10.32388/286jz0 |
| CDK Gene Mutation | | reference-entry | 10.32388/kf9klo |
| Willighagen, Egon | StatCVS on CDK | | posted-content | 10.59350/q7ehm-v1m81 |
| Willighagen, Egon | CDK Literature #1 | | posted-content | 10.59350/g22fv-gtc07 |
| CDK | | book-chapter | 10.1007/978-3-540-47648-1_959 |
| Hu, X. | Cdc2: a monopotent or pluripotent CDK? | 2011/6 | journal-article | 10.1111/j.1365-2184.2011.00753.x |
| Willighagen, Egon | CDK Literature #2 | | posted-content | 10.59350/17nhx-htt54 |
| Huang, Linda | Faculty Opinions recommendation of Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. | 2007/4/23 | dataset | 10.3410/f.1080804.533727 |
| Supplementary file 1. CDK sequences used for phylogenetic analysis | | component | 10.7554/elife.10767.021 |
| Willighagen, Egon | Nightly CDK builds now available | | posted-content | 10.59350/s63wt-hbx56 |
| Apodaca, Richard L. | Updating Ruby CDK | | posted-content | 10.59350/yy9a2-wy148 |
| CDK Inhibitor SNS-032 | | reference-entry | 10.32388/2sggcz |
| Willighagen, Egon | The CDK data model #1 | | posted-content | 10.59350/4xfms-7nn46 |
| Willighagen, Egon | CDK-Taverna fully recognized | | posted-content | 10.59350/pk40z-7z702 |
| cdk | | book-chapter | 10.1007/3-540-29832-0_321 |
| CDK | | book-chapter | 10.1007/978-3-540-38918-7_5357 |
| Willighagen, Egon | CDK Module dependencies #2 | | posted-content | 10.59350/e7qrk-ypg78 |
| cdk | | book-chapter | 10.1007/3-540-29719-0_321 |
| Willighagen, Egon | CDK Workshop - Day #2 | | posted-content | 10.59350/f7vn0-kqz26 |
| Schreiner, S. | Kongenitale Kniegelenkluxation (CDK) | 2012/1 | journal-article | 10.1007/s00132-011-1874-7 |
| Carnero, A. | The INK4 Family of CDK Inhibitors | 1998 | book-chapter | 10.1007/978-3-642-71941-7_3 |
| CDK Inhibitors | | book-chapter | 10.1007/978-3-540-47648-1_963 |
| Valk, Ervin | CDK signaling via nonconventional CDK phosphorylation sites | 2023/11/1 | journal-article | 10.1091/mbc.e22-06-0196 |
| | | journal-issue | 10.55175/cdk.v48i6 |
| Grigoroudis, Asterios I. | Preparation of CDK/Cyclin Inhibitor Complexes for Structural Determination | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_4 |
| Alvira, Daniel | Drug Delivery Strategies of Chemical CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_12 |
| Apodaca, Richard L. | Ruby CDK for Newbies | | posted-content | 10.59350/50ebs-4zq55 |
| Willighagen, Egon | Single PDFs for CDK News articles | | posted-content | 10.59350/rgdzb-bfe36 |
| Willighagen, Egon | Java Server Pages with CDK functionality | | posted-content | 10.59350/3kvks-pdb73 |
| Willighagen, Egon | Atom typing in the CDK | | posted-content | 10.59350/wm7aq-eqz10 |
| Willighagen, Egon | Calculating geometrical properties with the CDK | | posted-content | 10.59350/sy6r5-pzw09 |
| Hu, Shanhu | Targeting anaphase catastrophe through CDK inhibition in lung cancer | | dissertation | 10.1349/ddlp.1623 |
| Degradation by Design: New Cyclin K Degraders from Old CDK Inhibitors | | component | 10.1021/acschembio.3c00616.s002 |
| | | journal-issue | 10.55175/cdk.v47i7 |
| Apodaca, Richard L. | CDK, the Ruby Way | | posted-content | 10.59350/49w1p-2y164 |
| Willighagen, Egon | Jumbo 5.0 and the CDK | | posted-content | 10.59350/y0mte-4ns18 |
| Willighagen, Egon | CDK close to entering Debian | | posted-content | 10.59350/dmspa-wyb25 |
| CDK Inhibitory Protein | | book-chapter | 10.1007/3-540-30683-8_276 |
| CDK | 2011 | book-chapter | 10.1007/978-3-642-16483-5_959 |
| CDK Inhibitors | 2011 | book-chapter | 10.1007/978-3-642-16483-5_963 |
| Gortat, Anna | Analysis of CDK Inhibitor Action on Mitochondria-Mediated Apoptosis | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_9 |
| | | journal-issue | 10.55175/cdk.v48i2 |
| Willighagen, Egon | The CDK data classes and change notifications | | posted-content | 10.59350/3xsm0-bt478 |
| | | journal-issue | 10.55175/cdk.v47i11 |
| CDK/JAK2/FLT3 Inhibitor TG02 Citrate | | reference-entry | 10.32388/xklmgh |
| Willighagen, Egon | CDK Workshop - Days #3 and #4 | | posted-content | 10.59350/kvq10-snm07 |
| CDK-Activating Kinase Assembly Factor MAT1 | | reference-entry | 10.32388/6s4tbs |
| Willighagen, Egon | CDK Bug Squash Party - Day 5 | | posted-content | 10.59350/paxbm-rac78 |
| | | journal-issue | 10.55175/cdk.v49i0 |
| Apodaca, Richard L. | Scripting CDK with JRuby | | posted-content | 10.59350/sxxfq-shj88 |
| CDK | 2016 | book-chapter | 10.1007/978-3-662-46875-3_100468 |
| Willighagen, Egon | CDK Bug Squash Party - Day 2 | | posted-content | 10.59350/wzs4m-9ky43 |
| Willighagen, Egon | The CDK/Metabolomics/Chemometrics Unconference results | | posted-content | 10.59350/f2ajz-tmr63 |
| Willighagen, Egon | CDK and the Java 6 beta | | posted-content | 10.59350/6az21-1dt76 |
| Willighagen, Egon | Jumbo 5.0 and CML support in CDK | | posted-content | 10.59350/dzvnw-3b413 |
| Hirai, Hiroshi | Evaluating Chemical CDK Inhibitors as Cell Death Inducers | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_14 |
| | | journal-issue | 10.55175/cdk.v47i10 |
| Willighagen, Egon | CDK Bug Squash Party - Day 1 | | posted-content | 10.59350/y5srm-hzx87 |
| | | journal-issue | 10.55175/cdk.v48i4 |
| Willighagen, Egon | UML diagram of CDK module dependencies | | posted-content | 10.59350/a3r1n-72841 |
| Upton, Jason W. | Evidence for CDK-Dependent and CDK-Independent Functions of the Murine Gammaherpesvirus 68 v-Cyclin | 2006/12/15 | journal-article | 10.1128/jvi.01722-06 |
| Apodaca, Richard L. | Porting MX - CDK-Compatible VF Implementation | | posted-content | 10.59350/xat1r-hcs92 |
| Lacy, Susan | Identification of a p130 domain mediating interactions with cyclin A/cdk 2 and cyclin E/cdk 2 complexes | 1997/5/22 | journal-article | 10.1038/sj.onc.1201085 |
| Apodaca, Richard L. | Scripting Molecular Fingerprints with Ruby CDK | | posted-content | 10.59350/xgf37-ggz21 |
| | | journal-issue | 10.55175/cdk.v47i8 |
| | | journal-issue | 10.55175/cdk.v47i12 |
| | | grant | 10.55776/tai3266225 |
| | | journal-issue | 10.55175/cdk.v47i9 |
| | | journal-issue | 10.55175/cdk.v48i5 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s002 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 1999/8/1 | report | 10.21236/ada378108 |
| Ruiz, E. Josué | Meiotic Inactivation of Xenopus Myt1 by CDK/XRINGO, but Not CDK/Cyclin, via Site-Specific Phosphorylation | 2008/10 | journal-article | 10.1016/j.molcel.2008.08.029 |
| Guevara, Tatiana | Evaluating the Effects of CDK Inhibitors in Ischemia–Reperfusion Injury Models | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_10 |
| | | journal-issue | 10.55175/cdk.v42i10 |
| Degradation by Design: New Cyclin K Degraders from Old CDK Inhibitors | | component | 10.1021/acschembio.3c00616.s001 |
| | | journal-issue | 10.55175/cdk.v48i1 |
| | | journal-issue | 10.55175/cdk.v48i3 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 2000/9/1 | report | 10.21236/ada392485 |
| Apodaca, Richard L. | CDK, the Ruby Way: RCDK-0.2.0 | | posted-content | 10.59350/ev966-zz940 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s003 |
| Lee, Young-Sam | Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates | 2007/4/6 | journal-article | 10.1126/science.1139080 |
| Guha, Rajarshi | rcdk: Interface to the 'CDK' Libraries | 2006/10/4 | dataset | 10.32614/cran.package.rcdk |
| GROTH, A | High-density growth arrest in Ras-transformed cells: low Cdk kinase activities in spite of absence of p27 Cdk-complexes | 2005/9 | journal-article | 10.1016/j.cellsig.2004.11.021 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s001 |
| Gallastegui, Edurne | Immunoprecipitation of Cdk–Cyclin Complexes for Determination of Kinase Activity | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_1 |
| Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors | | component | 10.1021/acs.jmedchem.3c01890.s004 |
| Cyclin-dependent Kinase (CDK) Inhibitor | | book-chapter | 10.1007/3-540-30683-8_390 |
| Fisher, Robert P | Faculty Opinions recommendation of Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation. | 2008/11/11 | dataset | 10.3410/f.1125916.583024 |
| Willighagen, Egon | CDK 1.0: a milestone after 7 year of development | | posted-content | 10.59350/qd21w-71g30 |
| Gangopadhyay, Aditi | The Prospects of CDK Targeting and Clinical Application of CDK Inhibitors in Cancer | 2018/12/5 | book-chapter | 10.2174/9781681087016118090008 |
| Apodaca, Richard L. | Drawing 2-D Structures with Structure-CDK | | posted-content | 10.59350/qxc8d-c1w35 |
| Schneider, Brandt | Role of the Cdk Inhibitor Sic 1 in Start | 1998/8/1 | report | 10.21236/ada359281 |
| Willighagen, Egon | The molecular QSAR descriptors in the CDK | | posted-content | 10.59350/47rre-wwc20 |
| Chiarelli, C | Cyclin D, CDK and CDK Inhibitors in Melanocytic Neoplasms. | 1997/8 | journal-article | 10.1097/00000372-199708000-00072 |
| lavarone, Antonio | Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15 | 1997/5 | journal-article | 10.1038/387417a0 |
| Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk) | | component | 10.1021/acschembio.7b00972.s002 |
| Willighagen, Egon | InChI's in LaTex and CDK News | | posted-content | 10.59350/hysd0-wvc09 |
| Pérez-Benavente, Beatriz | Cell Synchronization Techniques to Study the Action of CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_8 |
| Willighagen, Egon | Test results for the CDK 1.0.x branch | | posted-content | 10.59350/ry980-qya21 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v49i2.1746 |
| Willighagen, Egon | CDK News 2.3 and InChI's | | posted-content | 10.59350/z97vw-87009 |
| Synthesis of benzofuropyridine derivatives as CDK-5 inhibitors and anticancer agents | | dissertation | 10.58837/chula.the.2022.1218 |
| CDK | | other | 10.1002/0471684228.egp01945 |
| Guha, Rajarshi | rcdklibs: The CDK Libraries Packaged for R | 2009/1/8 | dataset | 10.32614/cran.package.rcdklibs |
| Willighagen, Egon | CDK Debug classes and fixing the ModelBuilder3D bug | | posted-content | 10.59350/6p49t-sj396 |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v48i12.1586 |
| Multiplexed Profiling of CDK Kinase Activities in Tumor Biopsies with Fluorescent Peptide Biosensors | | component | 10.1021/acssensors.4c00139.s001 |
| Willighagen, Egon | CDK Bug Squash Party - Day 3 and 4 | | posted-content | 10.59350/zwkym-aty79 |
| | | grant | 10.55776/t393 |
| Figure 3: The efficiency of tumor markers in distinguish CDK patients from healthy control. | | component | 10.7717/peerj.19240/fig-3 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v48i12.1589 |
| Many Hats for Cdk Inhibitor | 2006/1/10 | journal-article | 10.1126/stke.3172006tw468 |
| Futcher, A. B. | General Methods for Identifying G1-phase Substrates of Cdk Protein Kinases | 1999/6/1 | report | 10.21236/ada374137 |
| Willighagen, Egon | R/CDK install fails on GCC 4.0 systems | | posted-content | 10.59350/b1vyj-0kd63 |
| Palomino-Schätzlein, Martina | Metabolomic Applications to the Characterization of the Mode-of-Action of CDK Inhibitors | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_16 |
| CDK | 2008 | book-chapter | 10.1007/978-1-4020-6754-9_2580 |
| | | grant | 10.35802/065956 |
| Willighagen, Egon | CDK is now available from your nearest Debian mirror | | posted-content | 10.59350/g5s78-zqk90 |
| Guidato, Sonia | Cyclin D2 Interacts with cdk‐5 and Modulates Cellular cdk‐5/p35 Activity | 1998/1 | journal-article | 10.1046/j.1471-4159.1998.70010335.x |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v49i2.1745 |
| Willighagen, Egon | Janocchio: Jmol and CDK based 1H coupling constant prediction | | posted-content | 10.59350/rxzh8-9yr48 |
| Tsutsui, Taiki | Identification of target genes for the CDK subunits of the Mediator complex | 2011/12 | journal-article | 10.1111/j.1365-2443.2011.01565.x |
| Dutto, Ilaria | Assessing Cell Cycle Independent Function of the CDK Inhibitor p21CDKN1A in DNA Repair | 2016 | book-chapter | 10.1007/978-1-4939-2926-9_11 |
| -, - | Indeks Subjek | | journal-article | 10.55175/cdk.v49i1.1648 |
| CDK Inhibitors, Endocrine Therapy for Male Patients With Breast Cancer | 2019/3/8 | dataset | 10.1200/adn.19.190134 |
| -, - | Indeks Akhir Tahun | | journal-article | 10.55175/cdk.v48i12.1588 |
| CELL CYCLE-REGULATION OF THE FANCD2 PROTEIN VIA CDK-MEDIATED S592 PHOSPHORYLATION | | dissertation | 10.23860/thesis-cantres-velez-juan-2020 |
| Nishizawa, Masafumi | Mouse Cyclin-dependent Kinase (Cdk) 5 Is a Functional Homologue of a Yeast Cdk, Pho85 Kinase | 1999/11 | journal-article | 10.1074/jbc.274.48.33859 |
| -, - | Indeks Penulis | | journal-article | 10.55175/cdk.v49i1.1647 |
| Figure 7. Model of how meiotic cells inhibit DNA replication during the MI–MII transition. | | component | 10.7554/elife.33309.026 |
| Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk) | | component | 10.1021/acschembio.7b00972.s001 |
| Willighagen, Egon | Comparing JUnit test results between CDK trunk/ and a branch | | posted-content | 10.59350/zs3tv-pp865 |
| Apodaca, Richard L. | Source Code Documentation in Ruby: RDoc for Ruby CDK | | posted-content | 10.59350/jf1hb-6ev38 |
| Willighagen, Egon | Open Source Java tool chain: CDK compiles and JUnit tests run | | posted-content | 10.59350/933ah-c7f36 |
| Willighagen, Egon | Protein support in Bioclipse using Jmol and the CDK | | posted-content | 10.59350/23wn4-1nt07 |
| Willighagen, Egon | Modern chemistry in the CDK: beyond the two-atom bond | | posted-content | 10.59350/h2ytc-6pt51 |
| Lone, Waseem | Silicon-tethered colchicine aryne cyclo-adduct as a potent molecule for the abrogation of epithelial to mesenchymal transition via modulating cell cycle regulatory CDK-2 and CDK-4 kinases | | posted-content | 10.26434/chemrxiv-2024-rs3lh |
| Apodaca, Richard L. | From IUPAC Name to Molecular Formula with Ruby CDK | | posted-content | 10.59350/1nn38-3ef94 |
| Zettelmeyer, Florian | CDK Digital Marketing: Addressing Channel Conflict with Data Analytics | 2014 | reference-book | 10.4135/9781473969650 |
| Willighagen, Egon | Trouble running the CDK JUnit tests with Cacao and Kaffe | | posted-content | 10.59350/rn78z-r7j37 |
| Shimotohno, Akie | CDKPhosphorylation | | other | 10.1002/9781119312994.apr0336 |
| Apodaca, Richard L. | MX Performance Comparison #3: Substructure Search in MX and CDK | | posted-content | 10.59350/n4y52-t3a30 |
| Apodaca, Richard L. | Agile Chemical Informatics Development with CDK and Ruby: RCDK-0.3.0 | | posted-content | 10.59350/c8h7w-n4922 |
| Futcher, A. B. | General Methods for Identifying Gl-phase Substrates of Cdk Protein Kinases. | 1998/6/1 | report | 10.21236/ada366953 |
| Protein kinase (CDK/MAK) | | book-chapter | 10.1007/978-3-540-49756-1_63 |
| Ringer, Lymor | Role of p53 in cdk Inhibitor VMY-1-103-induced Apoptosis in Prostate Cancer | 2013/11/1 | report | 10.21236/ada592440 |
| Anurogo, Dito | Cancer Stem Cells | | journal-article | 10.55175/cdk.v48i11.1549 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/8/16 | peer-review | 10.1111/odi.13687/v1/review1 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/8/17 | peer-review | 10.1111/odi.13687/v1/review2 |
| Purnamasari, Maretta Rosabella | Iktiosis Vulgaris | | journal-article | 10.55175/cdk.v47i10.1085 |
| Prasetya, Damar | Varisela Neonatal | | journal-article | 10.55175/cdk.v47i12.1239 |
| Cyclin-Dependent Kinase (CDK) Inhibitors: StructureActivity Relationships and Insights into the CDK2 Selectivity of 6Substituted 2Arylaminopurines | | component | 10.1021/acs.jmedchem.6b01254.s002 |
| Apodaca, Richard L. | From SMILES to InChI: Rino, CDK, and Ruby Java Bridge | | posted-content | 10.59350/hra9n-qry69 |
| Pohl, M. | GWK/CDK-Bank | 1994/1/1 | book-chapter | 10.4337/9781781954218.00152 |
| Cyclin-Dependent Kinase (CDK) Inhibitors: StructureActivity Relationships and Insights into the CDK2 Selectivity of 6Substituted 2Arylaminopurines | | component | 10.1021/acs.jmedchem.6b01254.s001 |
| EMPIAR dataset | | | 10.6019/empiar-10438 |
| Shimotohno, Akie | CDK Phosphorylation | | book-chapter | 10.1002/9780470988923.ch5 |
| Dutta, Anindya | Action of the p53 Effector, p2l, on its Targets: Cyclin cdk and PCNA | 1998/10/1 | report | 10.21236/ada368460 |
| Apodaca, Richard L. | Easily Calculate TPSA Descriptors from SMILES Strings Using Ruby CDK | | posted-content | 10.59350/8xxp3-b8077 |
| Roovers, Kristin | Role of Cyclin D1 and cdk Inhibitors in Breast Cancer Pathogenesis | 2002/5/1 | report | 10.21236/ada407447 |
| Apodaca, Richard L. | MX Performance Comparison #2: Exhaustive Ring Perception in MX and CDK | | posted-content | 10.59350/tv70e-5c238 |
| Rusli, Richardo | Retinitis Pigmentosa | | journal-article | 10.55175/cdk.v47i7.597 |
| Durandau, Eric | Cross-regulation between CDK and MAPK control cellular fate | | posted-content | 10.1101/274787 |
| Yu, Bo | Downregulation of Cyclin D1 Alters cdk 4- and cdk 2-Specific Phosphorylation of Retinoblastoma Protein | 2000/6 | journal-article | 10.1006/mcbr.2000.0238 |
| Cheng, Weiyan | Recent development of CDK inhibitors: An overview of CDK/inhibitor co-crystal structures | 2019/2 | journal-article | 10.1016/j.ejmech.2019.01.003 |
| Ringer, Lymor | Role of p53 in cdk Inhibitor VMY-1-103-Induced Apoptosis in Prostate Cancer | 2012/9/1 | report | 10.21236/ada567635 |
| Kawauchi, Takeshi | Extra‐cell cycle regulatory functions of cyclin‐dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders | 2013/3 | journal-article | 10.1111/gtc.12029 |
| Nishizawa, Masafumi | Phosphorylation of Sic1, a Cyclin-dependent Kinase (Cdk) Inhibitor, by Cdk Including Pho85 Kinase Is Required for Its Prompt Degradation | 1998/9 | journal-article | 10.1091/mbc.9.9.2393 |
| Apodaca, Richard L. | Open Benchmarks for Cheminformatics: First Performance Comparison Between CDK and MX | | posted-content | 10.59350/7nc6k-w4216 |
| Cyclin‐Dependent Protein Kinase (
CDK
) | | other | 10.1002/0471684228.egp02997 |
| Srivastava, Mansi | Lineage-specific CDK activity dynamics characterize early mammalian development | | posted-content | 10.1242/prelights.38013 |
| Cyclin dependent kinase (CDK) | 2010/11 | journal-article | 10.1038/scibx.2010.1319 |
| Cyclin-Dependent Protein Kinases (CDK) | 2008 | book-chapter | 10.1007/978-1-4020-6754-9_3981 |
| ., Sukamto | Penanganan Ketoasidosis Diabetik pada Anak | | journal-article | 10.55175/cdk.v49i9.2039 |
| CDK | 2006 | book-chapter | 10.1007/3-540-29623-9_10003 |
| Wysocki, Robert | CDK Pho85 targets CDK inhibitor Sic1 to relieve yeast G1 checkpoint arrest after DNA damage | 2006/10 | journal-article | 10.1038/nsmb1139 |
| Lawrenti, Hastarita | Hemofilia dan Perkembangan Terapinya | | journal-article | 10.55175/cdk.v48i9.1496 |
| Figure 4: The efficiency of tumor markers in distinguish CDK patients with normal serum creatinine from healthy controls. | | component | 10.7717/peerj.19240/fig-4 |
| Mahendra, Cipta | Peutz-Jeghers Syndrome | | journal-article | 10.55175/cdk.v48i12.1574 |
| Katz, Max | RichFaces CDK: Building Custom Components | 2011 | book-chapter | 10.1007/978-1-4302-3450-0_14 |
| Review for "ALG3 contributes to the malignant properties of OSCC cells by regulating CDK‐Cyclin pathway" | 2020/10/7 | peer-review | 10.1111/odi.13687/v2/review1 |
| Sanchez-Diaz, Alberto | The Mitotic Exit Network and Cdc14 phosphatase initiate cytokinesis by counteracting CDK phosphorylations and blocking polarised growth | 2012/8/29 | journal-article | 10.1038/emboj.2012.224 |
| Yuliana, Jeni | Aspek Klinis Ambliopia | | journal-article | 10.55175/cdk.v49i1.1639 |
| Pérez-Hidalgo, Livia | CDK Inhibitors | 2013 | book-chapter | 10.1007/978-1-4419-9863-7_12 |
| Apodaca, Richard L. | From InChI to Image with Ruby Open Babel and Ruby CDK | | posted-content | 10.59350/r891p-vmx14 |
| Apodaca, Richard L. | Cheminformatics for the Web: Convert SD Files to HTML with Ruby CDK | | posted-content | 10.59350/gvwgq-b0x50 |
| Turner, N. | Targeting the CDK 4-6 pathway | 2019/3 | journal-article | 10.1016/s0960-9776(19)30078-5 |
| Aprelikova, Olga | Both p16 and p21 Families of Cyclin-dependent Kinase (CDK) Inhibitors Block the Phosphorylation of Cyclin-dependent Kinases by the CDK-activating Kinase | 1995/8 | journal-article | 10.1074/jbc.270.31.18195 |
| Teo, Gloria | Diagnosis dan Tatalaksana Kegawatdaruratan Hiperkalemia | | journal-article | 10.55175/cdk.v48i8.1447 |
| Fig. 1. Ovarian enlargement and lack of blood flow in the CDK regimen with a full bladder | | component | 10.17816/psaic575-154 |
| Chandra, Rudi | Tatalaksana Melanoma Maligna Kutaneus | | journal-article | 10.55175/cdk.v48i7.1453 |
| Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor | | component | 10.1021/acs.oprd.1c00255.s001 |
| Lawrensia, Sherly | Diagnosis dan Tatalaksana Artritis Tuberkulosis | | journal-article | 10.55175/cdk.v47i8.773 |
| RAYNAL, S | DIFFERENTIAL-EFFECTS OF TRANSFORMING GROWTH-FACTOR-BETA-1 ON PROTEIN-LEVELS OF P21 WAF AND CDK-2 AND ON CDK-2 KINASE-ACTIVITY IN HUMAN RD AND CCL64 MINK LUNG-CELLS | | journal-article | 10.3892/ijo.7.2.337 |
| Ogata, Ryohei | Resistance to cyclin-dependent kinase (CDK) 4/6 inhibitors confers cross-resistance to other CDK inhibitors but not to chemotherapeutic agents in breast cancer cells | 2021/1 | journal-article | 10.1007/s12282-020-01150-8 |
| When a CDK Is Really a Transcription Factor | 2005/1/11 | journal-article | 10.1126/stke.2662005tw14 |
| Prasetio, Adrian | Gangguan Psikiatri Terkait Kafein | | journal-article | 10.55175/cdk.v47i7.603 |
| Nitiyoso, Nugroho | Aspek Imunitas pada COVID-19 | | journal-article | 10.55175/cdk.v48i9.1497 |
| ., Suharto | Fisioterapi Kasus Cerebral Palsy Kuadriplegia Spastik | | journal-article | 10.55175/cdk.v49i9.2036 |
| p27
Kip1−/−
Strain 3 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg10 |
| Nitiyoso, Nugroho | Pilihan Pengobatan Sistemik pada Psoriasis | | journal-article | 10.55175/cdk.v49i3.1775 |
| Lone, Waseem Iqbal | Discovery of Colchicine Aryne Cyclo-Adduct as a Potent Molecule for the Abrogation of Epithelial to Mesenchymal Transition Via Modulating Cell Cycle Regulatory Cdk-2 and Cdk-4 Kinases | | posted-content | 10.2139/ssrn.4814175 |
| Lawrensia, Sherly | Lung Abscess: Diagnosis and Treatment | | journal-article | 10.55175/cdk.v48i5.1373 |
| | | grant | 10.55776/p19894 |
| Febriana, Lydia | Suplemen untuk Terapi Obesitas | | journal-article | 10.55175/cdk.v49i0.1964 |
| Fauzi, Ahmad | Haglund Deformity: Diagnosis and Treatment | | journal-article | 10.55175/cdk.v49i10.2067 |
| Yahya, Willy | Retinopati Prematuritas : Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v47i10.1080 |
| Cyclin dependent kinase (CDK) | 2010/3 | journal-article | 10.1038/scibx.2010.272 |
| Futcher, A. B. | General Methods for Identifying G1-Phase Substrates of Cdk Protein Kinases. | 1996/6/1 | report | 10.21236/ada323678 |
| EMPIAR dataset | | | 10.6019/empiar-10561 |
| Dai, Yun | CDK Inhibitors in Multiple Myeloma | 2008 | book-chapter | 10.1007/978-1-59745-564-0_22 |
| Meijer, Laurent | CDK Inhibitors | 2002 | book-chapter | 10.1016/b978-012476249-7/50008-4 |
| Cyclin dependent kinase (CDK) | 2012/4 | journal-article | 10.1038/scibx.2012.385 |
| Henri, P. | Psoriatic epidermis is associated with upregulation of
CDK
2 and inhibition of
CDK
4 activity | 2020/3 | journal-article | 10.1111/bjd.18178 |
| Bisbis, Badia | Cyclin-dependent Kinase (CDK) Inhibitors Regulate the CDK-Cyclin Complex Activities in Endoreduplicating Cells of Developing Tomato Fruit | 2006/3 | journal-article | 10.1074/jbc.m506587200 |
| Karyadi, Erlinda | Cutaneous Mucormycosis | | journal-article | 10.55175/cdk.v49i2.1740 |
| Larochelle, Stéphane | CDK-Activating Kinases: Detection and Activity Measurements | | book-chapter | 10.1385/1-59259-857-9:279 |
| Dai, Yun | CDK Inhibitors in Leukemia and Lymphoma | 2019/9/17 | book-chapter | 10.1201/9780429114670-15 |
| Putri, Zanty Rakhmania | Bell’s Palsy: Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v49i8.1986 |
| Pricelda, Alicia | Tren Terapi Age-Related Macular Degeneration | | journal-article | 10.55175/cdk.v48i12.1584 |
| Lukito, Johan Indra | Tinjauan atas Terapi Insulin | | journal-article | 10.55175/cdk.v47i9.917 |
| Karyadi, Erlinda | Cutaneous Mucormycosis | | journal-article | 10.55175/cdk.v49i2.1726 |
| Cicenas, Jonas | CDK Inhibitors and FDA: Approved and Orphan | | journal-article | 10.3390/cancers16081555 |
| Müllers, Erik | Cdk activity drives senescence from G2 phase | | posted-content | 10.1101/041723 |
| p27
Kip1−/−
Strain 2 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg9 |
| Chandra, Rudi | Pilihan Pengobatan Dermatologis Penuaan Periorbital | | journal-article | 10.55175/cdk.v47i12.1241 |
| Morgan, David O. | Principles of CDK regulation | 1995/3 | journal-article | 10.1038/374131a0 |
| Mahendro, Della Sulamita | Penggunaan Antivirus untuk COVID-19 | | journal-article | 10.55175/cdk.v48i7.1459 |
| Kristiningrum, Esther | Penggunaan Hydroxychloroquine dalam Tatalaksana Covid-19 | | journal-article | 10.55175/cdk.v47i12.1246 |
| Suryani, Adelia | Faktor-Faktor yang Memengaruhi Pigmentasi Manusia | | journal-article | 10.55175/cdk.v47i11.1195 |
| Permasutha, Made Bayu | Tinjauan atas Kanker Rongga Mulut | | journal-article | 10.55175/cdk.v48i3.1327 |
| -, Tommy | Angina Prinzmetal - Diagnosis dan Tatalaksana | | journal-article | 10.55175/cdk.v48i6.1431 |
| Kusumo, Inosensia Diajeng | Tinjauan Atas Pioderma | | journal-article | 10.55175/cdk.v49i4.1822 |
| CDK Inhibitor Triples PFS in Breast Cancer | 2013/1/1 | journal-article | 10.1158/2159-8290.cd-nb2012-149 |
| ASCO TAPUR, CDK Studies Endeavor to Fill Gaps in Personalized Cancer Care Research | 2024/12/1 | dataset | 10.1200/acon.24.00037 |
| Apodaca, Richard L. | CampDepict: Building a Simple SMILES Depict Web Application With JRuby, Structure CDK, and Camping | | posted-content | 10.59350/d2m6v-tag27 |
| Afifah Nurullah, Fitri | Tinjauan atas N-Nitrosodimethylamine (NDMA) | | journal-article | 10.55175/cdk.v47i12.1249 |
| Decision letter: CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading | 2016/12/19 | peer-review | 10.7554/elife.23352.021 |
| -, Carlson | Tatalaksana Demam pada Anak | | journal-article | 10.55175/cdk.v47i11.1200 |
| Johan, Michael | Evaluasi dan Tatalaksana Hipernatremia | | journal-article | 10.55175/cdk.v48i6.1441 |
| Palacios Blanco, Inés | CDK phospho-regulation of the Rad51-accessory factor Sfr1 and its role in meiotic recombination | | dissertation | 10.14201/gredos.161088 |
| Fanardy, Angeline | Toksin Botulinum untuk Kasus Urogenital | | journal-article | 10.55175/cdk.v48i3.1337 |
| Dinari, Nur Alfi | Miopia: Etiologi dan Terapi | | journal-article | 10.55175/cdk.v49i10.2069 |
| Ciatawi, Kartini | Patofisiologi Spinal Cord Injury | | journal-article | 10.55175/cdk.v49i5.1848 |
| Ciatawi, Kartini | Patofisiologi Spinal Cord Injury | | journal-article | 10.55175/cdk.v49i9.2032 |
| Stanley, Jone A. | Chromium-VI arrests cell cycle and decreases granulosa cell proliferation by down-regulating cyclin-dependent kinases (CDK) and cyclins and up-regulating CDK-inhibitors | 2011/7 | journal-article | 10.1016/j.reprotox.2011.05.007 |
| EMPIAR dataset | | | 10.6019/empiar-10431 |
| Mueller, Daniel | Abstract 2821: Characterization of CDK inhibitors in a biochemical assay using a comprehensive panel of human CDK-cyclin complexes | 2016/7/15 | journal-article | 10.1158/1538-7445.am2016-2821 |
| Wijaya, Sandy | Diagnosis dan Tatalaksana Polisitemia Vera | | journal-article | 10.55175/cdk.v47i7.596 |
| Lawrenti, Hastarita | Penghambat Immune Checkpoint untuk Terapi Kanker | | journal-article | 10.55175/cdk.v49i0.1966 |
| Shamsi, Zahra | Concestor kinase activation mechanism uncovers the cyclin dependence of CDK family kinases | | posted-content | 10.1101/410902 |
| Cherub, Jane | Terapi Antikoagulan pada COVID-19 | | journal-article | 10.55175/cdk.v48i6.1436 |
| Lukito, Johan Indra | Gunakan Insulin dengan CERMAT | | journal-article | 10.55175/cdk.v47i10.1093 |
| Setiawan, Michael | Mielopati Non Kompresif: Pendekatan Diagnosis | | journal-article | 10.55175/cdk.v47i9.909 |
| Dewi, Nadia Puspa | Aspek Klinis Dermatitis Seboroik | | journal-article | 10.55175/cdk.v49i6.1881 |
| Renita Sanyasi, Rosa De Lima | Sindrom Mona Lisa | | journal-article | 10.55175/cdk.v48i1.1258 |
| Irsyada Yusuf, Amry | Diagnosis dan Tatalaksana Kriptorkhismus | | journal-article | 10.55175/cdk.v48i3.1330 |
| Wijaya, Meiliyana | Meningitis Kriptokokus pada Penderita HIV | | journal-article | 10.55175/cdk.v48i1.1256 |
| p27
Kip1−/−
Strain 1 | 2001/10/3 | journal-article | 10.1126/sageke.2001.1.tg8 |
| Carrieri, Francesca Anna | CDK
1 and
CDK
2 regulate
NICD
1 turnover and the periodicity of the segmentation clock | 2019/7 | journal-article | 10.15252/embr.201846436 |
| Feinberg, Bruce A. | Prescribing preferences for hormone sensitive (HR+) metastatic breast cancer (mBC) in the CDK 4/6 inhibitor (CDK 4/6i) era. | 2020/5/20 | journal-article | 10.1200/jco.2020.38.15_suppl.e13058 |
| Decision letter: CDK control pathways integrate cell size and ploidy information to control cell division | 2020/12/20 | peer-review | 10.7554/elife.64592.sa1 |
| Wijaya, Lupita | Tatalaksana Nyeri Neuropatik Perifer dengan Sediaan Patch | | journal-article | 10.55175/cdk.v48i9.1484 |
| Tan, Christine | Trombosis pada Pasien COVID-19 | | journal-article | 10.55175/cdk.v48i12.1571 |
| Dianky, Amanda | Peran Nutrigenomik pada Tata Laksana Obesitas | | journal-article | 10.55175/cdk.v49i0.1965 |
| Besser, Alexandra | CDK Inhibitors in Normal and Malignant Cells | 2023 | book-chapter | 10.1016/b978-0-12-821618-7.00221-2 |
| Mahendrakrisna, Daniel | Tatalaksana Epilepsi Refrakter | | journal-article | 10.55175/cdk.v47i9.911 |
| 4-Arylazo-3, 5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects | | component | 10.1021/jm0605740.s001 |
| Ratna Sari, Ihda Zuyina | Gambaran Sistiserkosis dan Taeniasis | | journal-article | 10.55175/cdk.v49i3.1768 |
| Mahendra, Cipta | Terapi Berbasis Sel: Perkembangan Terkini | | journal-article | 10.55175/cdk.v49i3.1769 |
| Clinical Trial in Healthy Volunteers and Subjects With CDK | | journal-article | 10.31525/ct1-nct03893799 |
| Cyclin dependent kinase (CDK); p53 | 2012/10 | journal-article | 10.1038/scibx.2012.1028 |
| CRESCENZI, ELVIRA | Association of Bcl‐2 with Cyclin A/Cdk‐2 Complex and Its Effects on Cdk‐2 Activity | 2002/11 | journal-article | 10.1111/j.1749-6632.2002.tb04647.x |
| First CDK 4/6 Inhibitor Heads to Market | 2015/4/1 | journal-article | 10.1158/2159-8290.cd-nb2015-028 |
| Decker, T | Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27 | 2002/3/1 | journal-article | 10.1038/sj.leu.2402389 |
| Mostafa, Heba H. | Herpes Simplex Virus 1 Upregulates p35, Alters CDK-5 Localization, and Stimulates CDK-5 Kinase Activity during Acute Infection in Neurons | 2015/5 | journal-article | 10.1128/jvi.00106-15 |
| Sondhi, Sham M. | Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases | 2006/6 | journal-article | 10.1016/j.bmc.2006.01.054 |
| Chandra, Rudi | Aspek Dermatologi Penuaan Kulit Periorbital | | journal-article | 10.55175/cdk.v47i9.920 |
| -, Cecile | Diagnosis dan Tatalaksana Paroxysmal Nocturnal Hemoglobinuria | | journal-article | 10.55175/cdk.v48i7.1452 |
| Falco, Giulia De | Cdk Inhibitors: Background and Introduction | | book-chapter | 10.1385/1-59259-401-8:01 |
| -, Filberto | Diagnosis dan Tatalaksana Congenital Talipes Equino Varus (CTEV) | | journal-article | 10.55175/cdk.v48i1.1270 |
| Grant, Steven | CDK inhibitors and immune responses | 2009/8/15 | journal-article | 10.4161/cc.8.16.9346 |
| Luminturahardjo, Winarko | Peranan Probiotik dalam Penanganan Infeksi COVID-19 | | journal-article | 10.55175/cdk.v48i5.1371 |
| Bird, R.Curtis | The Cyclin/Cyclin-Dependent Kinase (cdk) Complex | 1997 | book-chapter | 10.1016/b978-012100160-5/50006-3 |
| A novel and robust molecular switch actuating the quantitative model of eukaryotic Cdk control | | proceedings-article | 10.18699/sbb-2022-104 |
| Kumala, Marcia | Suplementasi Vitamin B1 untuk Pasien Sepsis | | journal-article | 10.55175/cdk.v47i8.783 |
| Review for "Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p27" | 2021/6/23 | peer-review | 10.1098/rsob.210125/v1/review2 |
| Title | Description | Published | Added |
| DTIC ADA412793: Chemotherapy of Late Stage Breast Cancer Targeted Towards Cell Cycle Regulatory Components | Our original goal was to target cell cycle regulatory components as a potential therapy for breast cancer. The target p16 is a tumor suppressor and a CDK inhibitor and is inactivated by gene methylation. The drug 5-aza-2'deoxycytidine (5-Aza-CdR), an inhibitor of DNA methylation, is targeted for reexpression of a repressed p16 in late stage breast cancer patients. Re-activation of the p16 gene in cells in which the gene is methylated will restore normal growth control and be efficacious in treatment of breast cancer. A mouse model for the action of the drug was developed and used to test the efficacy of the drug. | 2002 | 2018-05-12T16:53:07Z |
| Redacting PII data at The Very Group with Amazon Comprehend | This three-part series demonstrates how to use graph neural networks (GNNs) and Amazon Neptune to generate movie recommendations using the IMDb and Box Office Mojo Movies/TV/OTT licensable data package, which provides a wide range of entertainment metadata, including over 1 billion user ratings; credits for more than 11 million cast and crew members; 9 million movie, TV, and entertainment titles; and global box office reporting data from more than 60 countries. Many AWS media and entertainment customers license IMDb data through AWS Data Exchange to improve content discovery and increase customer engagement and retention. The following diagram illustrates the complete architecture implemented as part of this series. To demonstrate the OOC search functionality with a simple example, we split the IMDb knowledge graph into customer-catalog and out-of-customer-catalog. We mark the titles that contain \"Toy Story\" as an out-of-customer catalog resource and the rest of the IMDb knowledge gr; | 2023 | 2023-01-29T23:46:41Z |
| DTIC ADA360338: Development and Use of Novel Tools to Directly Screen for Substrates of Cyclin Dependent Kinases | Cell division is a central and primary biological function. Many problems in biology and medicine center around cell division, but without a knowledge of the mechanism by which division is controlled, these problems are difficult to attack. The major transitions of the cell cycle are is controlled by a protein called a cyclin dependent kinase, or Cdk. The cell cycles of both yeast and human cells are controlled by a Cdk. Using the yeast two hybrid system I have isolated many novel Cdk interacting proteins in yeast, and these may be instrumental in controlling cell cycle progression. I have also isolate two exciting proteins which can only interact with a substrate trapping mutant of a yeast Cdk. These may be Cdk new substrates. I have also used the genomic technology of Gene Chips, to define the complete set of cell cycle regulated genes in yeast, and to characterize their controlling promoter elements. These two projects have yielded novel and exciting results, of interest to both the; | 1998 | 2018-04-22T05:07:32Z |
| In re: Dealer Management Systems Antitrust Litig. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-03-22T17:58:37Z |
| Bob Baker Volkswagen v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2018-09-16T22:44:00Z |
| ＰＨＯＮＫ ＦＲＩＤＡＹＳ | iNFMS - The Don Chronicles pt.1 | PHONK FRIDAY SEASON 3 | Episode 1 --------------------------------------------------------------- Produced by iNFMS | https://infms495.bandcamp.com/ Video Edit by iNFMS chapter 3: 𝖙𝖍𝖊 𝖉𝖔𝖓 𝖈𝖍𝖗𝖔𝖓𝖎𝖈𝖑𝖊𝖘 - [00:20] MAKE SOME ENDZ [03:14] SHE DONT EVEN SMOKE [06:23] ADRENOCHROME [09:48] ADRENOCHROME PT 2 [11:49] 200 THOUSAND ON MY WRIST [15:07] $CREWED UP [17:34] SMOKIN OUT - -special thanks: LORDKADO, STVSHBOI, PXSSXSSXD, BADRADIO and ANALOG BY NATURE - -audio drip: https://soundcloud.com/iaminfms/the-don-chronicles-vol-1 - https://www.analogbynature.tv https://www.badradio.nz Twitter - twitter.com/official_iNFMS Twitch - twitch.tv/analogbynature DLive - https://dlive.tv/cdk - Official Spotify Playlist: https://spoti.fi/2V5Jzqr Join : https://bit.ly/2UIIw08 ▶▶ATTENTION ARTISTS AND PRODUCERS▶▶ ----Submissions: http://bitSubmit.net/21 ---100% Free Music Distribution on spotify , itunes , and more http://www.amuse.io?utm_source=RC ▶▶Co; | 2020 | 2024-02-12T06:19:34Z |
| Dedos De Oro | Tracklist: 1. El Dedos De Oro - Teodoro Bello 2. El Ojo De Agua - Mario Quintero L. 3. Nieve De Sabores - Alfredo Araujo 4. Compra Y Venta - Jose Ontiveros M. 5. No Necesito De Claves - Jose Ontiveros M. 6. Soy De La Tierra De Villa - Carlos Ventura 7. El Primo - Mario Quintero L. 8. La Fuga Del Zorro - Teodoro Bello 9. La Fiera De Michoacan - Efren Avila 10. Las Novias Del Traficante - Francisco Quintero O. 11. De Tierra Pobre 12. Boda De Sangre - Teodoro Bello | 2002 | 2025-04-10T03:30:33Z |
| DTIC ADA411262: Targeting the AP-1 Transcription Factor for the Treatment of Breast Cancer | The AP-l transcription factor is a central component of many signal transduction pathways. We have shown that blocking AP-l by over-expressing a dominant negative form - of cJun (cjun-DN, Tam67) inhibits breast cancer cell growth. We hypothesize that- inhibition of AP-l blocks the cell cycle, reverses TAM-resistance of breast cancer cells, and suppression of AP-l in vivo causes regression of existing breast tumors. In the present study, we demonstrated that TAM67 inhibits breast cancer growth both in vitro and in vivo. We determined the mechanism by which AP-l blockade inhibits breast cancer growth. Our studies suggested that TAM67 inhibits breast cancer growth predominantly by inducing CDK inhibitors (such as P27), suppressing GI cyclins expression and reducing CDKs activity, thus inducing a cell cycle block. We also showed that TAM67 induces apoptosis in serum-free condition in breast cancer cells. We are currently investigating the molecular mechanism by which TAM67 causes a cell cy; | 2002 | 2018-05-12T03:54:47Z |
| The dynamics of strategy : mastering strategic landscapes of the firm | ix, 220 p. : 24 cm // Includes bibliographical references and index // 1. Introduction -- Pt. I. The Competitive Landscape -- 2. Models of Competition -- 3. Dynamics of Competition -- 4. Networks -- Pt. II. The Organizational Landscape -- 5. Organizational Dynamics -- 6. Managing Firm Complexity -- 7. Co-Evolution -- 8. Conclusion | 2009 | 2023-10-02T09:51:36Z |
| Mahatma Gandhi | | 2012 | 2024-01-04T12:38:14Z |
| CIA Reading Room cia-rdp83m00914r002300100097-4: PUBLICATION OF UNCLASSIFIED ANALYSIS | Approved For Release 2007/03/09: CIA-RDP83MOO914R002300100097-4 .xcacutlve Rayic4ig FEB 17 4 05 P4 ?8L MEMORANDUM FOR: Director of Central Intelligence OEXA 82-0455/1 17 FEB 1982 Director, ice o External Affairs SUBJECT: Publication of Unclassified Analysis 1. Action. Requested: Sign the attached letter to Gustav F. Papanek, Boston University, President of the Association for .Comparative Economic Studies. 2. Background: Pananek wrote you on 5 February 1982 to ask that you resume release of unclassified. CIA analysis to the public. (Tab A) The attached proposed response is consistent with your 20 January 1982 letter to Messrs. Becker and Horelick at the.Rand Corporation, and a more recent letter Bob Gates sent to Dr. Grossman of the University.of California on the same subject. (Tab B) It has been adjusted to avoid the look of a form letter, however, since it is likely that these people exchange letters with each other. 3. Recommendation: Sign the attached letter. U -:, Ui1- Director o; | 1982 | 2025-02-22T15:23:14Z |
| Mad Money : CNBC : November 7, 2018 6:00pm-7:00pm EST | Colorful financial analyst Jim Cramer offers his insights into the market. | 2018 | 2018-11-07T23:00:00Z |
| Identification of Genes Interacting with rnt-1 Through Large-Scale RNAi Screening in Caenorhabditis elegans. | This article is from G3: Genes|Genomes|Genetics , volume 3 . Abstract Although many critical roles of the RUNX family proteins have already been identified, little attention has been given to how these proteins interact with other factors. Elucidating RUNX protein interactions will help extend our understanding of their roles in normal development and tumorigenesis. In this study, we performed large-scale RNAi screening to identify genes that genetically interact with rnt-1, the sole homolog of RUNX protein in the nematode Caenorhabditis elegans. To this end, we took advantage of the fact that C. elegans can survive a severe loss of RNT-1 function with only mild phenotypes, and we looked for genes that caused a synthetic phenotype in the rnt-1 mutant background. We identified seven genes, three of which (cdk-8, cic-1, and sur-2) are involved in transcription, two of which (pgp-2 and cct-5) are involved in stress response, and two of which (D2045.7 and W09D10.4) are involved in signalin; | 2013 | 2014-10-28T00:42:20Z |
| Quantifying the CDK inhibitor VMY-1-103's activity and tissue levels in an in vivo tumor model by LC-MS/MS and by MRI. | This article is from Cell Cycle , volume 11 . Abstract The development of new small molecule-based therapeutic drugs requires accurate quantification of drug bioavailability, biological activity and treatment efficacy. Rapidly measuring these endpoints is often hampered by the lack of efficient assay platforms with high sensitivity and specificity. Using an in vivo model system, we report a simple and sensitive liquid chromatography-tandem mass spectrometry assay to quantify the bioavailability of a recently developed novel cyclin-dependent kinase inhibitor VMY-1-103, a purvalanol B-based analog whose biological activity is enhanced via dansylation. We developed a rapid organic phase extraction technique and validated wide and functional VMY-1-103 distribution in various mouse tissues, consistent with its enhanced potency previously observed in a variety of human cancer cell lines. More importantly, in vivo MRI and single voxel proton MR-Spectroscopy further established that VMY-1-103 ; | 2012 | 2014-10-26T21:07:18Z |
| On & On | Tracklist: 1. Let Jesus Love You 2. I'll Praise His Name 3. To Teach Me 4. On & On 5. In Spite Of It All 6. Show Some Sign 7. Healing Hands 8. It Is Well With My Soul 9. Hallelujah, Amen! | 1994 | 2025-03-20T07:54:14Z |
| Immunohistochemical characterization of cyclin dependent kinase-4 in different histological grades of oral leukoplakia and oral squamous cell carcinoma. | This article is from Journal of Oral and Maxillofacial Pathology : JOMFP , volume 18 . Abstract Background:: Cyclin dependent kinase-4 (CDK4) encoded by CDK gene, is a heterodimer protein of cell cycle in G1-S transition. This study aimed to characterize the CDK4 immunoreactivity in different histological grades of oral leukoplakias (OLs) and oral squamous cell carcinomas (OSCCs) and also aims to discuss its probable role in the tumor biogenesis. Materials and Methods:: Expression of CDK4 was investigated in total of 52 samples including OL (15), OSCCs (30) and normal oral tissues (07). A labeled Streptavidin-Biotin immunohistochemistry assay was performed and staining intensity was evaluated. Results:: The staining pattern was similar in all tissues and was located in both nuclei and cytoplasm. Dysplastic epithelium displayed a progressive increase in nuclear expression of CDK4 when compared to normal tissues. Also, positive staining cytoplasm was highly evident in OSCC with loss of d; | 2014 | 2014-10-21T00:20:34Z |
| Herpes Simplex Virus 1 (HSV-1) ICP22 Protein Directly Interacts with Cyclin-Dependent Kinase (CDK)9 to Inhibit RNA Polymerase II Transcription Elongation. | This article is from PLoS ONE , volume 9 . Abstract The Herpes Simplex Virus 1 (HSV-1)-encoded ICP22 protein plays an important role in viral infection and affects expression of host cell genes. ICP22 is known to reduce the global level of serine (Ser)2 phosphorylation of the Tyr1Ser2Pro3Thr4Ser5Pro6Ser7 heptapeptide repeats comprising the carboxy-terminal domain (CTD) of the large subunit of RNA polymerase (pol) II. Accordingly, ICP22 is thought to associate with and inhibit the activity of the positive-transcription elongation factor b (P-TEFb) pol II CTD Ser2 kinase. We show here that ICP22 causes loss of CTD Ser2 phosphorylation from pol II engaged in transcription of protein-coding genes following ectopic expression in HeLa cells and that recombinant ICP22 interacts with the CDK9 subunit of recombinant P-TEFb. ICP22 also interacts with pol II in vitro. Residues 193 to 256 of ICP22 are sufficient for interaction with CDK9 and inhibition of pol II CTD Ser2 phosphorylation but do not; | 2014 | 2014-10-01T20:40:34Z |
| DTIC ADA474451: Mechanism of Antineoplastic Action of Bisperoxovanadium Compound | This work describes studies into the mechanism of action of bisperoxovanadium (bpVs) compounds and into the basic biology and regulation of Cdc25A phosphatase. The bpVs cause phase-specific cell cycle arrest (G1/S), dose-dependent inhibition of Cdk activity, and persistent Rb hypophosphorylation upon release from serum starvation, consistent with Cdc25A inhibition. Further, they cause p53-independent apoptosis. Oxidative stress and DNA damage do not appear to be involved in their mechanism of action, given that: p53 is not induced by bpV(Me2Phen); p53 and p21 status do not affect IC50; depletion of glutathione or supplementation with antioxidants does not affect IC50, in contrast to other heavy metal-based agents. With respect to regulation, the Cdc25A nuclear localization signal (NLS) was identified and characterized. Data suggest that phosphorylation of S292, adjacent to the NLS, may promote nuclear localization. In the unperturbed cell cycle, S292 phosphorylation, a Chk1/2 target, a; | 2005 | 2018-06-15T10:53:58Z |
| Chroniques syndicales internationalistes - CNT | La prochaine émission radio des Chroniques syndicales internationalistes sera demain, samedi 24 décembre 2022, à 11H30 sur Radio libertaire (89.4fm ou en ligne en direct sur http://media.radio-libertaire.org:8080/radiolib.mp3 , en podcast également), et animée par le secrétariat international de la CNT. Nous dédions cette émission aux camarades du Conseil Démocratique des Kurdes en France (CDK-F) en diffusant l'intégralité de leur conférence de presse qui a eu lieu le vendredi 23 décembre à 18h30 à Paris, suite à l'attaque sanglante ciblant des camarades Kurdes, faisant 3 morts et 4 blessés graves. Nous appelons à rejoindre massivement la manifestation appelée par le CDK-F ce samedi 24 décembre à 12H Place de la République à Paris. Tout notre soutien aux camarades Kurdes, Un coup porté contre l'un-e d'entre nous est un coup porté contre nous tous.toutes ! La solidarité sera toujours notre arme ! Le Secrétariat International de la CNT | 2022 | 2022-12-27T17:10:55Z |
| BUbbs Picture | Sak Picture | | 2005-10-24T02:53:40Z |
| Corridos del Pueblo Con Banda | Tracklist: 1. Carga ladeada - Paulino Vargas 2. El michoacano - Federico Villa 3. El tamal - Joel Elizalde 4. Terrible cuerno de chivo - Los Tahures 5. El contrabando de Nogales - Lalo Elizalde 6. Los dos hermanos - Federico Villa 7. Las parcelas de Mendoza - Joel Elizalde 8. El cabo de Michoacâan - Los Tahures 9. El gallo de San Juan - Lalo Elizalde 10. Sucediâo en la barranca - Federico Villa 11. El moro y la mora - Joel Elizalde 12. La bronco negra - Los Tahures | 2002 | 2025-03-31T06:01:33Z |
| Death is a silent room | | 1965 | 2023-08-29T22:36:40Z |
| Bailando Contigo | Tracklist: 1. Se Fue Mi Negra 2. Como Una Estrella 3. Bailando Apretao 4. Mentiroso 5. Reconciliación 6. Miami 7. Soñando Contigo 8. Cogio Carretera | 1991 | 2024-02-20T03:53:27Z |
| DTIC ADA420283: Resistance to Tamoxifen: A Consequence of Altered p27Kipl Regulation During Breast Cancer | While approximately 70% of breast cancers express the estrogen receptor (ER) at diagnosis, only two thirds of these will respond to antiestrogens such as Tamoxifen (TAM). Unfortunately, ER positive tumors that are initially responsive, invariably acquire resistance to hormonal therapies (reviewed in (1)).: TAM-resistant tumors usually show continued expression of the ER (2, 3). Estradiol regulates cell proliferation and development in the mammary gland. The elucidation of mechanisms whereby estradiol:ER influences cell cycle regulators and how these are blocked by Tamoxifen is highly relevant to the development of new treatments for steroid resistant breast cancer. Both estrogens and antiestrogens influence the cell cycle during the early Ol phase (4). The cell cycle is governed by a family of cyclin dependent kinases (cdks), whose activity is regulated by positive effectors, the cyclins, by phosphorylation and by negative regulators, the cdk inhibitors (reviewed in (5-7)). p27 or kina; | 2002 | 2018-05-16T19:57:14Z |
| CDK Ventures, LLC v. Performance Shading Systems Inc. | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2017-07-18T21:40:09Z |
| github.com-aws-aws-cdk_-_2022-09-21_02-53-56 | The AWS Cloud Development Kit is a framework for defining cloud infrastructure in code AWS Cloud Development Kit (AWS CDK) The AWS Cloud Development Kit (AWS CDK) is an open-source software developmentframework to define cloud infrastructure in code and provision it through AWS CloudFormation. It offers a high-level object-oriented abstraction to define AWS resources imperatively usingthe power of modern programming languages. Using the CDK’s library ofinfrastructure constructs, you can easily encapsulate AWS best practices in yourinfrastructure definition and share it without worrying about boilerplate logic. The CDK is available in the following languages: JavaScript, TypeScript ( Node.js ≥ 14.15.0 ) We recommend using a version in Active LTS Python ( Python ≥ 3.6 ) Java ( Java ≥ 8 and Maven ≥ 3.5.4 ) .NET ( .NET Core ≥ 3.1 ) Go ( Go ≥ 1.16.4 ) Third-party Language Deprecation: language version is only supported until its EOL (End Of Life) shared by the vendor or commun; | 2022 | 2022-09-21T05:05:30Z |
| github.com-sottlmarek-DevSecOps_-_2021-11-29_22-24-32 | Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this Library of knowledge please create proper PR (Pull request) with description what you are adding following these set of rules: Clear description of PR (What tool, why, stars, maturity and topic) Keep it simple Fact over feelings or personal opinions Add source and follow the Library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently Open-source only Add only active projects Note: Currently this is early version of the library. I recommend PR after first official release. DevSecOps Library info: This library contains list of tools and methodologies accompanied with resources. The main goal is provide to the engineers guide trough opensource DevSecOps tooling. This repository covers only cyber security in cloud and DevSecOps scope. Table of Contents Defintition Tooling Precommit and threat modeling SAST DAST Supply chain and dependenci; | 2021 | 2021-11-30T06:31:12Z |
| Corridos Empolvados, Vol. 1 | Tracklist: 1. El numero uno - Memo Lugo 2. El rayo de Sinaloa - Paulino Vargas 3. Pacas de a kilo - Teodoro Bello 4. Alfalfa americana 5. Chico Fuentes - Paulino Vargas 6. Juan Ramos 7. Roderigo Lopez 8. La Rubia del moäno negro - Paulino Vargas 9. Setecientas libras 10. Contrabando de Juarez - Paulino Vargas 11. El Comandante 12. Fe en el Santito | 2002 | 2025-03-30T23:06:51Z |
| 14 Exitos, Vol. 2 | Tracklist: 1. Mi Pueblo / Fernando Villalona 2. Mi Vida Eres Tu / Fernando Villalona 3. Armonicemos / Fernando Villalona 4. Dejame Volver / Fernando Villalona 5. Coco de Agua / Fernando Villalona 6. Cumbia Merenguera / Fernando Villalona 7. Celos / Fernando Villalona 8. Santiago / Fernando Villalona 9. Sonâambulo / Fernando Villalona 10. Lo Que Tengo / Fernando Villalona 11. El Polvorete / Fernando Villalona 12. Cancavo y Convexo / Fernando Villalona 13. Sere / Fernando Villalona 14. Cantando / Fernando Villalona | 1989 | 2023-05-13T13:29:02Z |
| [CDK 014] Assault | An assault on the senses? An assault on modern society? An assault on South Arctic (I and II)? An assault on old video gaming equipment? Whatever the Assault, it’s gonna assault your ears – in the best way possible! Goatslacker is a Floridian chiptuner who also uses the occasional keyboards ‘n’ drums for his music. He has a GSOH, likes walks in the parks and cinema and WLTM a person with similar interests in phat basslines and tight drums. | 2008 | 2019-12-06T22:45:14Z |
| Cyclic strain upregulates VEGF and attenuates proliferation of vascular smooth muscle cells. | This article is from Vascular Cell , volume 3 . Abstract Objective: Vascular smooth muscle cell (VSMC) hypertrophy and proliferation occur in response to strain-induced local and systemic inflammatory cytokines and growth factors which may contribute to hypertension, atherosclerosis, and restenosis. We hypothesize VSMC strain, modeling normotensive arterial pressure waveforms in vitro, results in attenuated proliferative and increased hypertrophic responses 48 hrs post-strain. Methods: Using Flexcell Bioflex Systems we determined the morphological, hyperplastic and hypertrophic responses of non-strained and biomechanically strained cultured rat A7R5 VSMC. We measured secretion of nitric oxide, key cytokine/growth factors and intracellular mediators involved in VSMC proliferation via fluorescence spectroscopy and protein microarrays. We also investigated the potential roles of VEGF on VSMC strain-induced proliferation. Results: Protein microarrays revealed significant increases in VEGF ; | 2011 | 2014-10-27T22:12:00Z |
| An Essay on Marxian Economics | | 1942 | 2023-07-25T08:51:27Z |
| Ayer, Hoy y Siempre, Vol. 1 | Tracklist: 1. La Canelera 2. Sin Rencor 3. Morenita Encantadora 4. Rosalito 5. La Mala Sombra 6. Cruz de Madera 7. Se Que No Eres Libre 8. Morenita Querida 9. Sin Rivales 10. Ya No Sufras 11. Seras Para Mi 12. Que Nos Perdone Dios 13. Porque La Quiero 14. Porque Probaste El Fruto 15. No Soy Feliz 16. Tus Quince Años 17. Tu Eres 18. Traicion Por Amor 19. Mil Promesas 20. Pilares de Cristal | 2002 | 2025-04-24T00:24:25Z |
| Fire-Tongue | | 1922 | 2023-07-25T01:03:48Z |
| The Key to Classics: Chopin | Tracklist: 1. Chopin: Impromptu #4 In C Sharp Minor, Op. 66, CT 46, "Fantaisie-Impromptu" - Andrea Lucchesini 2. Etude in E (Tristesse) - Andrei Gavrilov 3. Chopin: Nocturne #2 In E Flat, Op. 9 - Tzimon Barto 4. Grande Valse Brillante in B-flat - Dmitri Alexeev 5. Chopin: Polonaise #6 In A Flat, Op. 53 - Maurizio Pollini 6. Valse in A Minor - Agustín Anievas 7. Etude in C Minor (Revolutionary) - Andrei Gavrilov 8. Chopin: Piano Concerto #1 In E Minor, Op. 11 - 2.Romance: Larghetto - Maurizio Pollini; Paul Kletzki: Philharmonia Orchestra 9. Etude in A-flat (Aeolian Harp) - Andrei Gavrilov 10. Chopin: Nocturne #13 In C Minor, Op. 48/1 - André Watts 11. Prelude in D-flat (Sostenuto) - Dmitri Alexeev 12. Prelude in B-flat Minor (Presto con fuoco) - Dmitri Alexeev 13. Chopin: Mazurka #13 In A Minor, Op. 17/4, CT 63 - Leif Ove Andsnes 14. Chopin: Ballade #1 In G Minor, Op. 23 - Maurizio Pollini | 1993 | 2019-08-17T02:46:12Z |
| The fortunate islands, a Pacific interlude;: An account of the pleasant lands and people in the United States' Trust Territory of the Pacific | | 1948 | 2024-01-04T16:01:13Z |
| Timely Activation of Budding Yeast APCCdh1 Involves Degradation of Its Inhibitor, Acm1, by an Unconventional Proteolytic Mechanism. | This article is from PLoS ONE , volume 9 . Abstract Regulated proteolysis mediated by the ubiquitin proteasome system is a fundamental and essential feature of the eukaryotic cell division cycle. Most proteins with cell cycle-regulated stability are targeted for degradation by one of two related ubiquitin ligases, the Skp1-cullin-F box protein (SCF) complex or the anaphase-promoting complex (APC). Here we describe an unconventional cell cycle-regulated proteolytic mechanism that acts on the Acm1 protein, an inhibitor of the APC activator Cdh1 in budding yeast. Although Acm1 can be recognized as a substrate by the Cdc20-activated APC (APCCdc20) in anaphase, APCCdc20 is neither necessary nor sufficient for complete Acm1 degradation at the end of mitosis. An APC-independent, but 26S proteasome-dependent, mechanism is sufficient for complete Acm1 clearance from late mitotic and G1 cells. Surprisingly, this mechanism appears distinct from the canonical ubiquitin targeting pathway, exhibitin; | 2014 | 2014-10-11T23:56:58Z |
| DTIC ADA435854: The Role of Ubiquitin E3 Ligase SCFSKP2 in Prostate Cancer Development | The CDK inhibitor p27Kipl acts as a negative regulator in the cell cycle and in prostate tumorigenesis. Either the loss of p27 or over-expression of its key regulator ubiquitin E3 ligase SKP2 is associated with prostate cancer. Prostate-sepcific expression of SKP2 is sufficient to induce hyperplasia, displasia, and low grade carcinoma in the mouse prostate gland. We propose to examine whether SKP2 cooperates with or is regulated by tumor suppressors such as Pten or Nkx3.1 implicated in prostatic tumorigenesis. In the past year, we have initiated the experiments by breeding and expansion of the colonies, crossing the SKP2 transgenic mice into Pten +/- strains, and ordering Nkx3.1 mice. Compound mice of SKP2 transgene and Pten +/- were made. Our initial studies suggest that there i&. no substantial difference in tumor frequency and grade in the SKP2 and Pten +/- compound mice versus single genetic alterations. These results suggest that PTEN may act through SKP2 for tumorigenesis. Since ; | 2005 | 2018-05-27T08:46:56Z |
| github.com-sindresorhus-awesome_-_2023-10-26_11-42-32 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app One Task Stop procrastination and get stuff done by focusing on one task at a time My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. API to get search engine results with ease. API to get search engine results with ease. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Develop; | 2023 | 2023-10-26T13:33:54Z |
| AWS Architecture Service Icons - Developer Tools (5909380) | Second set of Architecture Diagram Blocks - Developer Tools Starting from the Asset Package provided from AWS (https://aws.amazon.com/architecture/icons/), I created these Architecture tiles for the Developer Tools Services. Only modification to original svg provided from AWS was putting a 1mm back on all the plates so they would print as a single block. Modifications made with TinkerCAD. Developer Tools: - Amazon CodeCatalyst - Amazon Corretto - AWS Application Composer - AWS CDK - AWS Cloud Control API - AWS Cloud9 - AWS CloudShell - AWS CodeArtifact - AWS CodeBuild - AWS CodeCommit - AWS CodeDeploy - AWS CodePipeLine - AWS CodeStar - AWS Command Line Interface - AWS SDK - AWS X-Ray | 2023 | 2023-03-28T06:11:47Z |
| The ironic temper: Anatole France and his time | | 1932 | 2024-01-12T07:23:21Z |
| Cierra la Puerta | Tracklist: 1. Cierra la Puerta 2. Una Copa Mas 3. Paloma Begra 4. Ahora Por Idea 5. Mi Sufrir 6. Anselma 7. Mi Dia de Suerte 8. Imelda 9. Que Dolor 10. El Ronquidito | 2001 | 2024-07-11T12:56:48Z |
| Faust : drame fantastique en cinq actes, quatorze tableaux | 25 p. ; 31 cm // "Représenté pour la première fois, à Paris, sur le Théâtre de la Porte-Saint-Martin, le 27 septembre 1856." | 1912 | 2023-08-09T19:28:32Z |
| PS5 shipments up 400% from last year (in the US) | PlayStation 5’s could be a lot easier to come by this holiday season, Saints row devs plan to fix over 200 bugs in the next major update, and Splatoon 3 made up %69 of retail games sold in Japan last month. These stories and more in today’s video This video is a clip out of a live recording which you can watch here: https://youtu.be/YjJhrhj_Cdk Buy our shirt! https://is.gd/u3xCtA OR follow us on Twitter! https://twitter.com/DarthBurrit0 http://twitter.com/InsideGaming SOURCES [IGN] PS5 shipments up 400% https://www.ign.com/articles/playstation-5-us-shipments-are-up-400-from-last-year [GamesIndustry.biz] Splatoon 3 is selling at an alarming rate in Japan https://www.gamesindustry.biz/splatoon-3-sold-27m-boxed-copies-in-three-weeks-japan-monthly-charts [VGC] Saints Row patch will fix over 200 bugs https://www.videogameschronicle.com/news/the-first-major-saints-row-update-promises-over-200-bug-fixes-in-november/ [The Verge] New Meta Quest Pro play tested, will be $1500 https://www.the; | 2022 | 2024-03-15T15:41:54Z |
| github.com-sindresorhus-awesome_-_2021-12-29_16-51-20 | 😎 Awesome lists about all kinds of interesting topics My macOS app Pandan is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with G; | 2021 | 2021-12-29T23:33:05Z |
| DTIC ADA429736: TGF-Beta Resistance in Breast Cancer | Transforming growth factor-Beta (TGF-Beta) potently inhibits cell proliferation by causing cell cycle arrest at the Gl phase. Smad proteins mediate the TGF-Beta antiproliferative responses by regulating the expression of several cell cycle components. We have recently discovered that Smad3, a key Smad protein for the TGF-Beta antiproliferative responses, is a major physiological substrate for cyclin-dependent kinases CDK4 and cDK2. Except for the Rb family members, Smad3 is the only cDK4 substrate demonstrated so far. CDK phosphorylation of Smad3 inhibits its transcriptional activity and antiproliferative function. Since cyclin Dl that activates CDK4 and the related cDK6 is amplified or overexpressed in a high percentage of human breast cancers, we examined whether Smad3 is highly phosphorylated by CDK in breast cancers. Using primary human breast cancer tissue microarrays and a phosphopeptide antibody against a CDK phosphorylation site in Smad3, we have found that overexpression of cy; | 2004 | 2018-05-22T14:32:34Z |
| DR. IDA - THE INSPIRING STORY OF DR. IDA SCUDDER, FIFTY YEARS A MEDICAL MISSIONARY IN INDIA. | | 1959 | 2023-12-29T19:48:32Z |
| West Hollywood Movers.pdf (PDFy mirror) | This public document was automatically mirrored from PDFy . Original filename: West Hollywood Movers.pdf URL: https://pdf.yt/d/M2VcwciF_cdk_IN4 Upload date: November 18, 2014 09:52:26 | 2014 | 2014-11-18T10:00:35Z |
| Check-List of Birds of the World. Volume IV | | 1940 | 2023-07-29T08:55:41Z |
| The Early theory of equations : on their nature and constitution : translations of three treatises | 218 p. ; 23 cm // On the recognition of equations / by François Viète -- A new discovery in algebra / by Albert Girard -- On the nature and constitution of equations / by Florimond de Beaune | 1986 | 2023-12-22T11:17:45Z |