| Title | Description | Published | Added |
| The three Jameses | | 1962 | 2025-05-22T16:21:27Z |
| Second international meeting of the international society for neurochemistry | | 1969 | 2025-09-08T04:17:18Z |
| Irradiation And The Nervous System | | 1963 | 2025-09-11T15:24:38Z |
| The civil war centennial: A report to the congress | | 1968 | 2025-07-30T19:58:01Z |
| Regional neurochemistry | | 1961 | 2025-09-08T03:28:35Z |
| Research in physiology | | 1971 | 2025-09-08T00:26:07Z |
| Scientists In Organizations | | 1966 | 2025-09-11T18:21:23Z |
| De Racine Au Parthenon: Essais Sur La Litterature Et L'Art A L'age Classique | | 1977 | 2025-09-04T14:43:38Z |
| John Gay, his place in the eighteenth century | | 1938 | 2023-12-27T15:46:10Z |
| Marine molluscan genera of western north america | | 1963 | 2025-09-08T08:50:24Z |
| AD #3850 - Lyriq Now #2 in Cadillac Sales; GM Backs Off 1 Million EV Goal by 2025; Chinese Suppliers Race Into Mexico | - GM Backs Off 1 Million EV Goal by 2025- Lyriq Now #2 in Cadillac Sales- Forecasts BEVs to Hit 50% U.S. Sales by 2030- Cyberattack Cost Dealers $1 Billion- Lucid Claims Most Efficient EV- Stellantis Sues Another Supplier- Stellantis To Sell Recycled Oil- TotalEnergies to Install 3,000 Chargers in UK- With New A5 Audi Has No Coupe or Convertible- Chinese Suppliers Race Into Mexico- Suddenly EREVs Make A Lot of Sense | 2024 | 2024-11-16T17:25:08Z |
| Education and society in modern Germany | | 1949 | 2023-07-25T04:04:04Z |
| John O'Neil Johnson Toyota, LLC v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2018-09-16T15:37:44Z |
| 534: How Toma is Transforming Car Dealerships with Voice AI Technology | Host Chad Pytel interviews Monik Pamecha, the Co-Founder and CEO of Toma, a company specializing in AI for the automotive industry. Monik discusses how Toma automates phone calls for car dealerships, enhancing customer service and streamlining interactions. Despite advancements in digital communication, phone calls remain crucial in the automotive sector, and Toma leverages AI to improve these experiences significantly.Monik shares his journey in the tech industry, detailing Toma's evolution from experimenting with different AI applications to focusing on voice AI. He explains the challenges and successes faced along the way, highlighting how AI technology has matured since his early work with chatbots in 2016. The conversation reveals how Toma's voice AI quickly gained user traction, validating their focus on this innovative technology.The episode also delves into the practical implementation of Toma's AI solutions in the automotive industry. Monik emphasizes the importance of integra; | 2024 | 2025-03-09T20:57:37Z |
| The King of Fighters 2002: (BR) PPSh-41 vs(BR) [CDK]-Shaka - 2023-01-27 13:30:18 | (BR) PPSh-41 vs (BR) [CDK]-Shaka - 2023-01-27 13:30:18 Fightcade replay id: 1674826218824-5406 #fightcade #kof2002 #[CDK]-Shaka #PPSh-41 For more videos check out: https://fightcadevids.com | | 2023-01-27T18:11:11Z |
| Cdk-mediated phosphorylation of the Kv?2 auxiliary subunit regulates Kv1 channel axonal targeting. | This article is from The Journal of Cell Biology , volume 192 . Abstract Phosphorylation of Kvβ2 releases Kv1 channels from microtubules to control their specific distribution at the axonal membrane. | 2011 | 2014-10-24T23:30:53Z |
| Are phylogenetic trees suitable for chemogenomics analyses of bioactivity data sets: the importance of shared active compounds and choosing a suitable data embedding method, as exemplified on Kinases. | This article is from Journal of Cheminformatics , volume 5 . Abstract Background: ‘Phylogenetic trees’ are commonly used for the analysis of chemogenomics datasets and to relate protein targets to each other, based on the (shared) bioactivities of their ligands. However, no real assessment as to the suitability of this representation has been performed yet in this area. We aimed to address this shortcoming in the current work, as exemplified by a kinase data set, given the importance of kinases in many diseases as well as the availability of large-scale datasets for analysis. In this work, we analyzed a dataset comprising 157 compounds, which have been tested at concentrations of 1 μM and 10 μM against a panel of 225 human protein kinases in full-matrix experiments, aiming to explain kinase promiscuity and selectivity against inhibitors. Compounds were described by chemical features, which were used to represent kinases (i.e. each kinase had an active set of features and an ina; | 2013 | 2014-10-28T15:40:11Z |
| [CDK 017] NSF File | Californian badass TristEndo is a Famitrackin’ motherfucker – and this album is CDK’s first all NSF release! A very rock influenced release, it’s a surefire way to get your fists pumping, and TristEndo doesn’t even need to resort to excessive unce! I’m especially loving the song ‘Destination’ – TristEndo is an artist to look out for in 2008/2009! There are two downloads, one with the MP3s and NSFs of the album, and a NSF only version! For those not in the know, a NSF (or NES Sound File) file is a chiptune only file, which (even though it has a tiny size) is less compressed than the mp3! So download a NSF player (I recommend VirtuaNSF (go to “Other program / data”) , whack this in and enjoy!) Or you could, y’know, just put the mp3s in your media player and enjoy them that way. | 2008 | 2019-12-06T23:51:18Z |
| [CDK 035] Josstin Timberlake - eatfuck | [CDK 035] Josstin Timberlake - eatfuck | 2009 | 2020-01-03T02:21:31Z |
| [CDK 012] Spurs Of A Dead Ranger | YEEE-HAW! Sparkyboy , possibly South Africa’s only chipartist, has unleashed this heaven for us – It’s one of the more unique releases out there, utilising everything from Game Boys to his toy guitar collection! I’m loving it all at the moment, especially ‘Gloom’ – what an opener! | 2008 | 2019-12-06T22:32:39Z |
| Social Behavior | | 1978 | 2025-09-11T18:35:52Z |
| The fury out of time | | 1965 | 2023-08-09T07:48:05Z |
| DTIC ADA303157: Role of Changes in the Expression of Cyclins and Retinoblastoma Protein in the Development of Breast Cancer. | In the initial year of the grant, we have carried out the bulk of the studies to characterize breast cancer cell lines with respect to overexpression of cyclin Dl protein and the presence of Rb (retinoblastoma) protein (Specific Aim No. 1). In addition, we have begun examination of surgically obtained breast cancer tissue samples for cyclin Dl protein overexpression and Rb protein content (Specific Aim No. 6). Since the original grant proposal was submitted, advances in our understanding of cell cycle regulation, and in particular advances in our understanding of the importance of defects in cell cycle regulation to the development of cancer, have proceeded at a rapid pace( )( ). In order to incorporate these advances into our investigation of cell cycle regulatory defects in breast cancer, we have expanded and reoriented some aspects of our approach. This has included a detailed assessment of the levels of cyclin dependent kinase (cdk) 4 and cdk 6, and of the cdk4/cdk6-specific cdk in; | 1995 | 2018-03-26T00:06:56Z |
| Periodic systems and their relation to the systematic analysis of molecular data | xxvi, 629 p., 8 p. of plates : 24 cm. + // Microfiches in pocket on front flyleaf // Includes bibliographies and index | 1989 | 2023-12-23T07:53:35Z |
| The saintmaker's Christmas Eve | | 1955 | 2023-08-11T09:11:11Z |
| The story of W.T. Grant and the early days of the business he founded | | 1954 | 2024-06-24T16:28:55Z |
| linuxbrew cdk | linuxbrew cdk | | 2021-04-07T20:55:45Z |
| Psychology of Personal Adjustment Student's Introduction to Mental Hygience | | 1949 | 2025-09-10T00:53:02Z |
| the zambesi doctors | | 1964 | 2025-06-16T09:45:55Z |
| IUMA: cdk Dashiell | Started like 6 months ago, now dominating the arts of sampling and sythetizing, I've decided to become a house dj, even got myself a couple of Gemini XL-400 II Turntables and a Gemini PMX 40 Mixer to start practicing for what I've greatly planned is my first presentation in a couple of years. That doesn't means that i've stopped producing! Actually I'm working with the Mirage corporation, a producing crew from Orlando, and another producer from Wisconsin, Da Corster. With both these influences I've learned a lot more and have applied it on this two new songs I got...Enjoy! :) | | 2012-05-18T17:23:07Z |
| CIA Reading Room cia-rdp62-00634a000200010059-3: CIA ELINT TRAINING PROGRAM INITIAL REPORT OF THE EAS SUB-COMMITTEE ON TRAINING 17 DECEMBER 1958 | Approved For Releas'2005/11/17 : CIA-RDF CONFIDENTIAL CIA ELINT TBAINING PROGRAM Initial Report of the EAC Sub-Committee on Training 17 December 1958 A. BACKGROUND: The EAC Sub-Committee on ELINT Training has held three meetings during which the following points were considered and, agreed upon: 1. Purpose of a CIA FLINT Training Program a. To prepare technical personnel for assignments to specific ELINT activities when and where required by the Agency ELINT Program. b. To acquaint non-technical personnel not partici- pating directly in the Agency ELINT Program with the capa- bilities and potential of DINT as a scientific intelligence tool. 2. Categories of personnel. needing training Intercept Operators; Data Reduction Personnel Maintenance Engineers R&D Engineers Intelligence Analysts Operations Personnel Administrators 3. Methods of training Document No. no CN, N(!E tat class. ^ DECI,AST,-,rrD Class. C"',1.r- aC: Aut: Date: a. Internal CIA courses b. On-the-job (training site and op; | 1958 | 2024-05-26T01:59:38Z |
| CIA Reading Room cia-rdp83m00914r002700200048-3: REQUEST FOR SPEAKING ENGAGEMENT - CHIEF EXECUTIVE S FORUM, PALM SPRINGS, CALIFORNIA | Approved For Release 2007/03/15: CIA-RDP83M0091 2-fR009g~l~ 3 OEXA 82-0226 MEMORANDUM FOR: Director of Central Intelligence Director, fT-ice o External Affairs STAT SUBJECT: Request for Speaking Engagement - Chief Executive's Forum, Palm Springs, California 1. Action Requested: Regret an invitation to speak to the Chief Executive's Forum in Palm Springs on 21 February. 2. Background: Public Affairs received this invitation by telephone from Leo Greenland, Program Chairman of the Chief Executive's For m. A formal invitation is in the mail. Greenland says you met at home in New York. You are committed to Palm Beach 19-23 February. 3. Recommendation: To ease Greenland's problem in arranging for another speaker, authorize Public Affairs to telephone your regrets. Director of Central Intelligence (Date) /s/ _ - ___ T2- Director of Central Intelligence (Date) STAT STAT OEXA/CEW/cdk/27 Jan 82/x7676 Distribution: Orig - Addressee DDCI - ER 1 - D/OEXA 1 - OEXA Registry 1 - C/PAD (To Be Returned; | 1982 | 2025-02-22T15:15:54Z |
| CIA Reading Room cia-rdp85m00364r002204220050-8: SYMPOSIUM ON SPECIAL OPERATIONS | Approved For Release 2008/01/16: CIA-RDP85M00364R002204220050-8 ER 83-0460/2 OEXA 83-0201/2 MEMORANDUM FOR: Director of Central Intelligence Director, Office of External Affairs SUBJECT: Symposium on Special Operations ee 1. Action Requested: None; for information only. 2. Background: A symposium on Special Operations took place on 4-5 March at Fort McNair. You will recall you were invited to participate but declined because you believed it to=be inappropriate. I arranged for CIA's faculty liaison officer at the National Defense University to attend as an observer and to report his impressions to you. His report is attached in the form of a Memorandum for the Record. The program agenda is also attached. 3. Recommendation: None. Attachments: A/S OEXA/PAD/CEW/cdk/22 Mar 83/7676 Distribution: Orig - Addressee 1 - D/OEXA 1 - DD/OEXA 1 - ER 83-0460/2 1 - OEXA 83-0201/2 1- 1 - Reading Board 1 - CEW Chron 1 - PA(1 Suhi_ w/cnv incoming Approved For Release 2008/01/16: CIA-RDP85M00364R002204220; | 1983 | 2026-07-11T20:17:36Z |
| die mikromorphologie der menschlichen zahnpulpa | | 1970 | 2025-09-04T05:39:32Z |
| Het bericht ‘CdK haalt ongemeen fel uit naar de NAM’ | This document is issued on date 2015-05-27. | 2015 | 2018-03-14T20:02:09Z |
| The life of Edward, Earl of Clarendon, Lord High Chancellor of England | | 1911 | 2024-01-12T08:38:15Z |
| Various Artists * 33,333 Steps To A Power Ov The Darkness Leagues | Various Artists * 33,333 Steps to a Power ov the Darkness Leagues (Disc one) 01. DJ R3V3R3ND MURD3R * !33,333 STEPS TO A POWER OV THE DARKNESS LEAGUES! 02. sOuL_sCientiSt * More Fiyah Mix 03. FIGURATIVE THEATRE * MEGAMARKET UTOPIA 04. Hel.Razor * Slave 2 The System 05. dreDDup * We Fuck Until Dawn 06. Moray Eel * Hellish Adoption 07. Cryogenic Implosion * Delete Humanity 08. The Apocryphal Order * Beyond The Depraved Scope Of Salvation 09. Come To My Rise * Play A Game 10. The Rinn * Voices 11. Crimson Blue * L.M.A. 12. Severed Fifth * Blackening 13. Spiritual Dissection * Across A Frozen Hell 14. Returning We Hear the Larks * Nascence in the Caverns of Mount Olympus 15. Cuntworm * Seduced By Damnation 16. Earslaughter * Roka Smrti (Disc two) 01. DiSloCaTed * Megazord 02. Cyber Snake * War 03. Circlerun * 13 04. Obsidian Shell * Misanthropia 05. Dawn Of Tears * Since They're Gone 06. Operación Mutante * Matanza 0; | 2013 | 2013-11-26T13:29:39Z |
| The ChipMusic Hour - Covers Special | Podcast The ChipMusic Hour Episode 003 – Originally aired 01 July 2010 on KCC Live. | 2010 | 2018-05-26T10:12:02Z |
| DTIC ADA443026: Radiation Sensitization in Breast Cancer via Targeting Survivin Expression | We proposed to determine whether overexpression- of surviving results in radio resistance and the possible mechanisms; whether irradiation down regulates p34(CDC2) and its mechanism in vascular endothelium and whether CDK (cyclin dependent kinase) inhibitors sensitize it to radiation injury; the mechanism of surviving- deregulation in breast cancer and whether inhibition of surviving or its regulator, p34(CDC2) abolishes radio resistance. We found that overexpression of surviving leads to radiation resistance and CDK inhibitors result in radiosensitization. We also found that deregulation of surviving in breast cancer is mediated by Stat3 (Signal transducer and activator of transcription). Co-inhibition of surviving and Stat3 results in significantly increased sensitization of breast cancer. In the next two years, we will determine the biological significance of combining surviving inhibitors or CDK inhibitors with radiotherapy in xenograft models of breast cancer. The proposed study w; | 2005 | 2018-05-30T23:48:34Z |
| DTIC ADA410428: Development of Inhibitors That Selectively Disrupt Substrate Recognition by Cyclin-Dependent Kinases | Upregulation of cyclin/cdk activity and the resulting deregulation of the cell cycle is a common feature in the malignant transformation of breast epithelial cells and thus makes cyclin/cdks an attractive target for drug design. The long-term goal of our work is to develop inhibitors which inhibit cyclin/cdk activity by disrupting the interaction between cyclins and their substrates, an association that requires a sequence motif in the substrate termed a Cy motif. Cy or RXL motifs are general purpose motifs for the interaction of cellular factors with cyclins. Recent work in our laboratory has shown that these motifs are critical determinants of both substrate recognition and specificity and function by targeting molecules to particular cyclin/cdk complexes. During the first year of grant support, we have made significant advancements into understanding substrate recognition by cyclin-dependent kinases. This work provides the framework for the development of Cy motif-derived peptides a; | 2002 | 2018-05-11T22:33:13Z |
| Studies On The Structure & Development of Vertebrates | | 1930 | 2025-09-04T07:17:09Z |
| The mystery of baptism | | 1901 | 2025-05-22T17:56:48Z |
| the new testament a new translation | | 1913 | 2025-06-17T02:27:47Z |
| THE VIGILANTES OF MONTANA | | 1929 | 2025-05-22T17:16:53Z |
| Pride Flag Raised in Silver Spring | Montgomery County celebrates Pride Month Music provided by Manhattan Production Music. Montgomery Community Media (MCM) is the only independent, nonprofit organization providing access to public media (public access television and broadband media) directly to Montgomery County’s over one million residents as well as the resident non-profit organizations, associations and businesses. We engage, educate and empower individuals and the community to express diverse viewpoints. Stay up to date on news in Montgomery County! » Subscribe to MCM here: https://goo.gl/fi9sqQ » Check out MCM for more: https://www.mymcmedia.org Follow MCM on these platforms! » Facebook: https://goo.gl/89YTJN » Twitter: https://twitter.com/mymcmedia » Instagram: https://goo.gl/BkuFnD For more Montgomery County, Maryland residents can tune to Comcast channels 21 and 995 | 2022 | 2022-06-02T01:32:19Z |
| Canonical Non-Homologous End Joining in Mitosis Induces Genome Instability and Is Suppressed by M-phase-Specific Phosphorylation of XRCC4. | This article is from PLoS Genetics , volume 10 . Abstract DNA double-strand breaks (DSBs) can be repaired by one of two major pathways—non-homologous end-joining (NHEJ) and homologous recombination (HR)—depending on whether cells are in G1 or S/G2 phase, respectively. However, the mechanisms of DSB repair during M phase remain largely unclear. In this study, we demonstrate that transient treatment of M-phase cells with the chemotherapeutic topoisomerase inhibitor etoposide induced DSBs that were often associated with anaphase bridge formation and genome instability such as dicentric chromosomes. Although most of the DSBs were carried over into the next G1 phase, some were repaired during M phase. Both NHEJ and HR, in particular NHEJ, promoted anaphase-bridge formation, suggesting that these repair pathways can induce genome instability during M phase. On the other hand, C-terminal-binding protein interacting protein (CtIP) suppressed anaphase bridge formation, implying that CtIP fu; | 2014 | 2014-10-06T07:32:29Z |
| The Fourteenth Commonwealths: Vermont and The States That Failed | | 1960 | 2023-12-22T15:00:33Z |
| DTIC ADA429736: TGF-Beta Resistance in Breast Cancer | Transforming growth factor-Beta (TGF-Beta) potently inhibits cell proliferation by causing cell cycle arrest at the Gl phase. Smad proteins mediate the TGF-Beta antiproliferative responses by regulating the expression of several cell cycle components. We have recently discovered that Smad3, a key Smad protein for the TGF-Beta antiproliferative responses, is a major physiological substrate for cyclin-dependent kinases CDK4 and cDK2. Except for the Rb family members, Smad3 is the only cDK4 substrate demonstrated so far. CDK phosphorylation of Smad3 inhibits its transcriptional activity and antiproliferative function. Since cyclin Dl that activates CDK4 and the related cDK6 is amplified or overexpressed in a high percentage of human breast cancers, we examined whether Smad3 is highly phosphorylated by CDK in breast cancers. Using primary human breast cancer tissue microarrays and a phosphopeptide antibody against a CDK phosphorylation site in Smad3, we have found that overexpression of cy; | 2004 | 2018-05-22T14:32:34Z |
| CDK-120 | | | 2021-04-17T01:59:16Z |
| CIA Reading Room cia-rdp91-00403r000200500046-0: FR:BARBIERI R TO:BARDENHEUER P | Research on Vackarmoderle Reaction.Note 11. On the Maolianism of theYormatiou of lutovuul S-,alfur inPolythionic Acid9l, by Ro Barbieri*ITALIANp perlVvI 920, 1%2* 0-6?5NTO 72-12316-07BJuly 72Studleo on the Weakenrodar Reaotion.Note 1. Thiaoulphurie Acids as ProbableIntermediate Produatep by Re Barbieri.ITALIAIT, parp Ricerea Scientifica.Far&a 11, Hendleonti.Vol 2j No 1,, 19620 pp 62-67073July 72investigations of the Reaction H2StSO2Analytical Procedures for Separatingand Breaking Down Maercquantities ofNfur Componanto in Research WithS , by Ro Barbieri*ITALIAN# porp ifigalVol 30, 1960l pp 1509-1517UTO 72-11838-07BJune 72.191 ( [erawl. M2911AVIM, Gliuscme). ami" 63-129098eHiuf['MbaMj. 1. Barbieri, R*AtULYSIS OF ORGANOMETALUC CONIOUNDS. 17. Taghavint, G.DITIMONATES OF RjPbCI AND R2PbC]- f19621.10p.K-H50 K-H121 MOdf M. BaJilgo, U.K -H - 1117IV1aromer,r1 1 - a-V. Kresge-Hooker7YRm Of [U] U, y) 1960, Science Mraryv. 30, no. 12, p. 1963-1968. Associatca, Detroit, Mich.DESCMMRS: 0=1cal andysi; | 1983 | 2026-03-26T07:30:01Z |