| Title | Description | Published | Added |
| The three Jameses | | 1962 | 2025-05-22T16:21:27Z |
| Second international meeting of the international society for neurochemistry | | 1969 | 2025-09-08T04:17:18Z |
| Irradiation And The Nervous System | | 1963 | 2025-09-11T15:24:38Z |
| A Little Extra Effort | | 2007 | 2023-07-25T22:15:33Z |
| Research in physiology | | 1971 | 2025-09-08T00:26:07Z |
| Scientists In Organizations | | 1966 | 2025-09-11T18:21:23Z |
| De Racine Au Parthenon: Essais Sur La Litterature Et L'Art A L'age Classique | | 1977 | 2025-09-04T14:43:38Z |
| Marine molluscan genera of western north america | | 1963 | 2025-09-08T08:50:24Z |
| AD #3850 - Lyriq Now #2 in Cadillac Sales; GM Backs Off 1 Million EV Goal by 2025; Chinese Suppliers Race Into Mexico | - GM Backs Off 1 Million EV Goal by 2025- Lyriq Now #2 in Cadillac Sales- Forecasts BEVs to Hit 50% U.S. Sales by 2030- Cyberattack Cost Dealers $1 Billion- Lucid Claims Most Efficient EV- Stellantis Sues Another Supplier- Stellantis To Sell Recycled Oil- TotalEnergies to Install 3,000 Chargers in UK- With New A5 Audi Has No Coupe or Convertible- Chinese Suppliers Race Into Mexico- Suddenly EREVs Make A Lot of Sense | 2024 | 2024-11-16T17:25:08Z |
| Education and society in modern Germany | | 1949 | 2023-07-25T04:04:04Z |
| github.com-infracost-infracost_-_2022-03-24_17-01-48 | Cloud cost estimates for Terraform in pull requests💰📉 Love your cloud bill! Infracost shows cloud cost estimates for Terraform. It enables DevOps, SRE and engineers to see a cost breakdown and understand costs before making changes , either in the terminal or pull requests. This provides your team with a safety net as people can discuss costs as part of the workflow. Quick start 1. Install Infracost Assuming Terraform is already installed, get the latest Infracost release: macOS Homebrew: shbrew install infracost Linux/macOS manual download:```sh Downloads the CLI based on your OS/arch and puts it in /usr/local/bin curl -fsSL https://raw.githubusercontent.com/infracost/infracost/master/scripts/install.sh | sh``` Docker and Windows users see here . 2. Get API key Register for a free API key, which is used by the CLI to retrieve prices from our Cloud Pricing API, e.g. get prices for instance types. No cloud credentials or secrets are sent to the API and you can also self-host it. s; | 2022 | 2022-03-24T20:04:58Z |
| github.com-serverless-stack-serverless-stack_-_2022-02-07_09-07-40 | 💥 SST makes it easy to build serverless apps. Set breakpoints and test your functions locally. https://serverless-stack.com Serverless Stack (SST) is a framework that makes it easy to build serverless apps. It's an extension of AWS CDK and it features: A Live Lambda Development environment Support for setting breakpoints and debugging in VS Code Support for deploying to multiple environments and regions Higher-level constructs designed specifically for serverless apps Zero-config support for JS and TS (using esbuild ), Go, Python, C#, and F# Quick Start Create your first SST app. ```bash Create your app $ npx create-serverless-stack@latest my-sst-app$ cd my-sst-app Start Live Lambda Development $ npx sst start Deploy to prod $ npx sst deploy --stage prod``` Documentation SST docs SST examples Public roadmap Feature requests Contributing to SST Follow us on Twitter and subscribe to our newsletter for updates. About SST We think SST can make it dramatically easier to build serverless ; | 2022 | 2022-02-07T09:45:28Z |
| github.com-sottlmarek-DevSecOps_-_2022-01-14_09-42-59 | Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevSecOps scope. Table of Contents Def; | 2022 | 2022-01-14T21:43:52Z |
| github.com-debezium-debezium_-_2021-12-10_11-35-09 | Change data capture for a variety of databases. Please log issues at https://issues.redhat.com/browse/DBZ. Copyright Debezium Authors.Licensed under the Apache License, Version 2.0 .The Antlr grammars within the debezium-ddl-parser module are licensed under the MIT License . English | Chinese | Japanese Debezium Debezium is an open source project that provides a low latency data streaming platform for change data capture (CDC). You setup and configure Debezium to monitor your databases, and then your applications consume events for each row-level change made to the database. Only committed changes are visible, so your application doesn't have to worry about transactions or changes that are rolled back. Debezium provides a single model of all change events, so your application does not have to worry about the intricacies of each kind of database management system. Additionally, since Debezium records the history of data changes in durable, replicated logs, your application can be stoppe; | 2021 | 2021-12-10T12:09:39Z |
| John O'Neil Johnson Toyota, LLC v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2018-09-16T15:37:44Z |
| The King of Fighters 2002: (BR) PPSh-41 vs(BR) [CDK]-Shaka - 2023-01-27 13:30:18 | (BR) PPSh-41 vs (BR) [CDK]-Shaka - 2023-01-27 13:30:18 Fightcade replay id: 1674826218824-5406 #fightcade #kof2002 #[CDK]-Shaka #PPSh-41 For more videos check out: https://fightcadevids.com | | 2023-01-27T18:11:11Z |
| Cdk-mediated phosphorylation of the Kv?2 auxiliary subunit regulates Kv1 channel axonal targeting. | This article is from The Journal of Cell Biology , volume 192 . Abstract Phosphorylation of Kvβ2 releases Kv1 channels from microtubules to control their specific distribution at the axonal membrane. | 2011 | 2014-10-24T23:30:53Z |
| Are phylogenetic trees suitable for chemogenomics analyses of bioactivity data sets: the importance of shared active compounds and choosing a suitable data embedding method, as exemplified on Kinases. | This article is from Journal of Cheminformatics , volume 5 . Abstract Background: ‘Phylogenetic trees’ are commonly used for the analysis of chemogenomics datasets and to relate protein targets to each other, based on the (shared) bioactivities of their ligands. However, no real assessment as to the suitability of this representation has been performed yet in this area. We aimed to address this shortcoming in the current work, as exemplified by a kinase data set, given the importance of kinases in many diseases as well as the availability of large-scale datasets for analysis. In this work, we analyzed a dataset comprising 157 compounds, which have been tested at concentrations of 1 μM and 10 μM against a panel of 225 human protein kinases in full-matrix experiments, aiming to explain kinase promiscuity and selectivity against inhibitors. Compounds were described by chemical features, which were used to represent kinases (i.e. each kinase had an active set of features and an ina; | 2013 | 2014-10-28T15:40:11Z |
| The leverage of labor : managing the Cortés haciendas in Tehuantepec, 1588-1688 | xxv, 245 p. ; 24 cm // Includes bibliographical references | 1989 | 2023-10-02T02:39:59Z |
| le bapteme des enfants | | 1948 | 2025-06-17T08:26:27Z |
| The fury out of time | | 1965 | 2023-08-09T07:48:05Z |
| Amarna in religion und kunst | | 1931 | 2025-05-22T20:55:21Z |
| Built By CDK For Server-Grade Reliability | Most Servers Can Run. This One Doesn’t Stop. Built By CDK For Server-Grade Reliability, This Server Is Configured For Continuous Operation—Where Uptime, Data Stability, And Consistent Throughput Are Non-Negotiable. From Optimized Storage Architecture To Balanced Memory Configuration, Clean Power Delivery, And Carefully Matched Components, Every Element Is Tuned To Work In Sync—Reducing Fail Points And Delivering Stable Performance For Years To Come. The Result? Uninterrupted 24x7 Operation. Reliable Data Handling At Scale. Consistent Performance Under Sustained Load. Long-Term Reliability You Can Depend On. Because In Server Environments, Stopping Isn’t An Option. Engineered By CDK. 📞 +91 92707 66589 🌐 www.designsbykira.in #cdkserver #serversolutions #datacenter #enterprisesystems #highavailability | | 2026-04-22T12:28:58Z |
| Baystate Ford Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2025-12-24T20:46:19Z |
| Psychology of Personal Adjustment Student's Introduction to Mental Hygience | | 1949 | 2025-09-10T00:53:02Z |
| Pride Flag Raised in Silver Spring | Montgomery County celebrates Pride Month Music provided by Manhattan Production Music. Montgomery Community Media (MCM) is the only independent, nonprofit organization providing access to public media (public access television and broadband media) directly to Montgomery County’s over one million residents as well as the resident non-profit organizations, associations and businesses. We engage, educate and empower individuals and the community to express diverse viewpoints. Stay up to date on news in Montgomery County! » Subscribe to MCM here: https://goo.gl/fi9sqQ » Check out MCM for more: https://www.mymcmedia.org Follow MCM on these platforms! » Facebook: https://goo.gl/89YTJN » Twitter: https://twitter.com/mymcmedia » Instagram: https://goo.gl/BkuFnD For more Montgomery County, Maryland residents can tune to Comcast channels 21 and 995 | 2022 | 2022-06-02T01:32:19Z |
| linuxbrew cdk | linuxbrew cdk | | 2021-04-07T20:55:45Z |
| odp-cdk-example | This is an archive of the project's publicly available source code and (where available) wiki repositories in bare git format, as well as related issues, pull requests and similar data from Github in JSON format, created on 2025-03-06. Project 'odp-cdk-example' from agency 'GSA', organization 'GSA'. Original project description: A serverless demonstration of the AWS CDK using Lambda, API Gateway, and Amazon S3 :rocket: | 2025 | 2025-03-12T18:53:16Z |
| yahoo-groups-2018-08-30T08-13-01Z-d5b6d2 | Yahoo! Groups API grab. Contains messages of the following groups: 08cecmcafriends 10thyec_documentations 10thyec_hrd 212sl_10 67_council_10-11 67_excom_10-11 aartedecompartilhar10 aborock accountantsworld advancedpca aggregator_game alcorp alyssamilanofansforever ambersdream api_2010 aulagelso_ceis aw88 basketball_ac beyondcircle bfpdatabasedevelopmentgroup bio11_lab_guzman blpholcimyli blueridgebirdexchange brandceo bsn2bnsginfo campusrecruitment cb7grupo252 cbhadventures ccih_aquiraz cdk_java cdpclub1011 cepe2000 clanrad_duty5 cmbe_ecrouves comissao_oab_se computer_lingap_1011 coolathawles cphic1994 csspvc daks_friends dapi_ii_2010a datasys_oracle_dba daytonactivitybagswap defensoriayplanmedico dhbn dimboola djjmatematika ec_azad_kermanshah_group economics_9a elenproj_ee energetica_iasi_1990 epdtributario-p04028 epmfam ex_smkbp feua2001 fkrkaceh fpik_umpgroup fumclovelandseniorhigh gangland2010 giusti12 houstonrubies h-v-v ibecbotucatu ibm379 ihrm_bertelsmann ipmiub iptn_2010 ipwija; | | 2018-08-30T08:13:09Z |
| Twinning And Diffusionless Transformations In Metals | | 1954 | 2025-09-12T13:34:58Z |
| die mikromorphologie der menschlichen zahnpulpa | | 1970 | 2025-09-04T05:39:32Z |
| THE EMPRESS FREDERICK | | 1956 | 2025-05-22T18:23:01Z |
| The United States and civilization | | 1943 | 2023-12-27T14:40:37Z |
| DTIC ADA443026: Radiation Sensitization in Breast Cancer via Targeting Survivin Expression | We proposed to determine whether overexpression- of surviving results in radio resistance and the possible mechanisms; whether irradiation down regulates p34(CDC2) and its mechanism in vascular endothelium and whether CDK (cyclin dependent kinase) inhibitors sensitize it to radiation injury; the mechanism of surviving- deregulation in breast cancer and whether inhibition of surviving or its regulator, p34(CDC2) abolishes radio resistance. We found that overexpression of surviving leads to radiation resistance and CDK inhibitors result in radiosensitization. We also found that deregulation of surviving in breast cancer is mediated by Stat3 (Signal transducer and activator of transcription). Co-inhibition of surviving and Stat3 results in significantly increased sensitization of breast cancer. In the next two years, we will determine the biological significance of combining surviving inhibitors or CDK inhibitors with radiotherapy in xenograft models of breast cancer. The proposed study w; | 2005 | 2018-05-30T23:48:34Z |
| DTIC ADA410428: Development of Inhibitors That Selectively Disrupt Substrate Recognition by Cyclin-Dependent Kinases | Upregulation of cyclin/cdk activity and the resulting deregulation of the cell cycle is a common feature in the malignant transformation of breast epithelial cells and thus makes cyclin/cdks an attractive target for drug design. The long-term goal of our work is to develop inhibitors which inhibit cyclin/cdk activity by disrupting the interaction between cyclins and their substrates, an association that requires a sequence motif in the substrate termed a Cy motif. Cy or RXL motifs are general purpose motifs for the interaction of cellular factors with cyclins. Recent work in our laboratory has shown that these motifs are critical determinants of both substrate recognition and specificity and function by targeting molecules to particular cyclin/cdk complexes. During the first year of grant support, we have made significant advancements into understanding substrate recognition by cyclin-dependent kinases. This work provides the framework for the development of Cy motif-derived peptides a; | 2002 | 2018-05-11T22:33:13Z |
| Kirkland City Council Regular Meeting Summary – January 2, 2024 | # Kirkland City Council Regular Meeting – January 2, 2024 The Kirkland City Council held a hybrid regular meeting on Tuesday, January 2, 2024, from 7:30 p.m. to 10:15 p.m. The council administered oaths to newly elected members, selected Mayor Kelli Curtis and Deputy Mayor Jay Arnold, approved a consent calendar, adopted the 2023-2028 Transportation Improvement Program, received a briefing on a Redmond paramedic co-location agreement, reviewed 2024 committee assignments, and discussed next steps after the November 2023 pool ballot measure failed. All seven councilmembers were present initially; Councilmember Jon Pascal left at 7:45 p.m. due to illness and was excused for the remainder of the meeting. ### Oaths, Mayor and Deputy Mayor Selection - Municipal Court Judge John Olson administered oaths of office to re-elected Councilmembers Kelli Curtis and Amy Falcone and newly elected Councilmember John Tymczyszyn. - The council voted 7-0 to select Kelli Curtis as Mayor and 7-0 to select; | 2024 | 2026-09-07T18:44:16Z |
| Black Sweater, White Cat 1.27.2007 | Broadcast to Podcast devoted to Creative Commons music. | 2007 | 2007-01-28T12:40:05Z |
| [CDK 034] Natty - These Days I Expect The Worst | [CDK 034] Natty - These Days I Expect The Worst | 2009 | 2020-01-02T22:35:46Z |
| [CDK 039] tenfold - Banaue's Second Wave Of Terrace Builders | [CDK 039] tenfold - Banaue's Second Wave Of Terrace Builders | 2009 | 2020-01-05T15:00:57Z |
| [CDK 042] Videovalvontaa – The END Is HNGH | [CDK 042] Videovalvontaa – The END Is HNGH | 2009 | 2020-01-05T18:34:36Z |
| [CDK 043] Multifaros - Dreams | [CDK 043] Multifaros - Dreams | 2010 | 2020-01-05T20:06:40Z |
| DTIC ADA429736: TGF-Beta Resistance in Breast Cancer | Transforming growth factor-Beta (TGF-Beta) potently inhibits cell proliferation by causing cell cycle arrest at the Gl phase. Smad proteins mediate the TGF-Beta antiproliferative responses by regulating the expression of several cell cycle components. We have recently discovered that Smad3, a key Smad protein for the TGF-Beta antiproliferative responses, is a major physiological substrate for cyclin-dependent kinases CDK4 and cDK2. Except for the Rb family members, Smad3 is the only cDK4 substrate demonstrated so far. CDK phosphorylation of Smad3 inhibits its transcriptional activity and antiproliferative function. Since cyclin Dl that activates CDK4 and the related cDK6 is amplified or overexpressed in a high percentage of human breast cancers, we examined whether Smad3 is highly phosphorylated by CDK in breast cancers. Using primary human breast cancer tissue microarrays and a phosphopeptide antibody against a CDK phosphorylation site in Smad3, we have found that overexpression of cy; | 2004 | 2018-05-22T14:32:34Z |
| Kenny Thomas Enterprises, Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2019-02-06T10:09:57Z |
| CELEBRITY MOTOR CAR, LLC v. CDK GLOBAL, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2025-06-17T09:38:39Z |
| DTIC ADA460911: Centrosome Amplification: A Potential Marker of Breast Cancer Agressiveness | The aim of our research is focused in elucidating the mechanisms by which the normal regulatory pathways coordinating centrosome duplication with cell cycle events may become uncoupled promoting breast cancer development, progression, chemoresistance and consequent poor outcome. The preliminary results reported in this grant suggest that the development and progression of breast cancer is a complex process involving the role of estrogens, growth factor signaling pathways and abrogation of the p53 protein leading to an inactivation of cell cycle checkpoints. We have demonstrated that although MCF-7 cells stable transfected with a dominant-negative p53 construct, maintain estrogen-dependent properties, the timing of centrosome duplication and cyclin/cdk complexes is deregulated following mitogen stimulation. Interestingly, over-expression of cyclin A plays a critical role in the development of centrosome amplification following hormone stimulation. We also have shown that genotoxic stres; | 2006 | 2018-06-08T19:21:35Z |
| DTIC ADA568573: Installation and Adjustment Procedure for the Portable Pier and PlaneWave CDK 17 Telescope | The purpose of this document is to highlight the initial steps necessary to mechanically set up and configure the PlaneWave CDK-17 in preparation for operational use. PlaneWave (www.planewave.com) acted as systems integrator during the specification, manufacture, and shipment of the telescope. These instructions outline the mechanical assembly, setup, and orientation of the portable pier (PPR), the Mathis fork arms, and the PlaneWave optical tube assembly (OTA). | 2012 | 2018-09-04T09:34:52Z |
| DTIC ADA388144: Role of the Cdk Inhibitor Sic 1 in Start | Cancer is essentially a disease of inappropriate proliferation due to a loss of normal cell cycle controls. The scope of this work was to study how cell cycle regulation by G1-phase Cyclin dependent kinases (Cdks) relates to breast cancer causation. The purpose of this proposal was to use yeast as an experimental system to examine the role of G1-Cdks in promoting cell cycle progression. The three major findings of this proposal are detailed below. First, we have shown that G1 cyclins are constitutively unstable and rate limiting for cell cycle progression 1. Second, the only essential function of G1 cyclins is to phosphorylate the B-type Cdk inhibitor, Sic1, and target it for degradation 2. Third, Sicl is one of few known in vivo substrates of yeast G1-Cdks 3. Sic1 mutants lacking several phosphorylation sites are stabilized and completely block cell cycle progression 1,3. Thus, the amount and phosphorylation state of Sic1 appears to determine the timing and size of cell division 3. By; | 2000 | 2018-05-01T09:11:17Z |
| github.com-aws-aws-cdk_-_2019-12-06_02-47-26 | The AWS Cloud Development Kit is a framework for defining cloud infrastructure in code AWS Cloud Development Kit (AWS CDK) The AWS Cloud Development Kit (AWS CDK) is an open-source software developmentframework to define cloud infrastructure in code and provision it through AWS CloudFormation. It offers a high-level object-oriented abstraction to define AWS resources imperatively usingthe power of modern programming languages. Using the CDK’s library ofinfrastructure constructs, you can easily encapsulate AWS best practices in yourinfrastructure definition and share it without worrying about boilerplate logic. The CDK is available in the following languages: JavaScript, TypeScript ( Node.js ≥ 10.3.0 ) Python ( Python ≥ 3.6 ) Java ( Java ≥ 8 and Maven ≥ 3.5.4 ) .NET ( .NET Core ≥ 3.0 ) Developer Guide | CDK Workshop | Getting Started | API Reference | Examples | Getting Help Developers use the [CDK framework] in one of thesupported programming languages to define reusable cl; | 2019 | 2019-12-06T10:24:49Z |
| DTIC ADA331989: Modulation of Cyclin Expression by c-Myc in Malignant and Nonmalignant Mammary Epithelial Cells. | The purpose of this grant was to support predoctoral training on an experimental model relevant to breast cancer etiology. Specifically, we explored the multifactorial nature of the interaction a growth factor (TGFalpha, which is commonly expressed both in benign and malignant proliferative disease of the human breast) and an oncogene (c-myc, whose gene is amplified and whose protein is inappropriately expressed in 20-30% of human breast tumors. Using a transgenic mouse model we observed that co-expression of these two genes was remarkably synergistic for onset and progression of cell survival and proliferation. While mye induced both p53 and bax death-promoting genes, TCFalpha promoted cell survival by inducing Bc1XL. In terms of the cell cycle, mye shortened G1 by modulating cyc1lin E, p27, and cdc25A, which activated cdk-2 and inactivated Rb. Thus, the interaction of TGFalpha and myc promoted shortened, aberrant cycles resulting in survival of genetically aberrant cells. | 1997 | 2018-04-09T05:12:15Z |
| DTIC ADB253632: Biochemical Characterization of Complexes With p21, a CDK Inhibitor | Progress through the cell cycle requires a concerted interplay between the growth promoting cyclin-dependent kinases (CDKs) and inhibitors such as p21/WAF1 that suppress the CDKs (CKIs). Despite the apparent ability of p21 to inhibit CDKs in vitro, its ability to inhibit these kinases in vivo has been a matter of controversy. In addition, while it is known that p21 participates in several complexes with the DNA polymerase processivity factor, PCNA, and cyclin and CDK proteins, it is not clear whether the full complement of p21-associated proteins has been defined. Nor has the function of such multimeric complexes in normal and transformed cells been thoroughly characterized. In light of experiments that indicate an important role for p21 as a downstream target of the p53 checkpoint protein and the observed defective response to DNA damage in mice lacking the p21 gene, it is essential that we understand the role of this protein in normal cells and how perturbations in its expression lev; | 1999 | 2018-03-07T10:29:35Z |