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Česká digitální knihovna

DostupnostNázevAutorDatumTypID
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Výroční zpráva2025periodical/periodicalvolume/periodicalitem/pageuuid:4adb403f-b839-4d2d-91e2-cd3d9ac4e3bd
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Meziměstská telefonní ústředna v Praze1929monograph/pageuuid:e20a6970-253d-11ee-8650-005056827e51
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Francouzská revoluce : populární dějiny bojů francouzské společnosti na sklonku 18. století. Díl 1. Zápas s královstvím1929monograph/pageuuid:840ef410-0803-11ed-be35-5ef3fc9bb22f
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X. mezinárodní sjezd slavistů : Sofija 14. - 22. 9. 1988 : bibliografie1994monograph/monographunit/pageuuid:45d9d8e0-a20e-11ed-9ac7-5ef3fc9bb22f
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Knižní novinky : časopis pro knihkupce, knihovny, nakladatele a čtenáře14.07.2003periodical/periodicalvolume/periodicalitem/pageuuid:88d3e6d0-1da5-11eb-9146-005056825209
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Veterinární medicína10.2010periodical/periodicalvolume/periodicalitem/pageuuid:6354c070-9632-11e8-b07a-5ef3fc9bb22f
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Galerie du Palais Royal gravée d'aprés les tableaux des différentes écoles qui la composent: avec un abrégé de la vie des peintres et une description historique de chaque tableau1786monograph/pageuuid:17fda895-f78f-4d9c-90ad-dca3cb9e3a75
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Eklogy a písně1916monograph/pageuuid:441044f0-f6f8-11e9-a329-005056827e51
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Starší literatura česká1910, 1911monograph/pageuuid:b4692cb0-bd01-11ea-b68c-005056827e52
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Mythy : básně Jaroslava Vrchlického : 1. cyklus (1874-1878)1915monograph/pageuuid:0998a060-f496-11e9-a329-005056827e51
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Stavební stroje: Seznam a výrobci1947monograph/pageuuid:0442b1d0-84ab-11e2-aa2b-005056827e51
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Základové měřictví pro nižší třídy gymnasií1886monograph/pageuuid:3c6e4dc0-d47b-11dc-b5f4-000d606f5dc6
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Katoličtí mučedníci doby husitské1927monograph/pageuuid:6de55980-a2be-11e3-b833-005056827e52
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Jan Slavík (1885-1978): a Czech historian of revolutions2009monograph/pageuuid:bdbc8db0-38cf-11ed-a118-5ef3fc9bb22f
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Základové měřictví pro nižší třídy gymnasií1893monograph/pageuuid:eca38890-36a8-11ee-9691-005056827e52
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Porovnávací tabulky měr a vah i příslušných cen ku snadnému užívání metrické soustavy v říši rakouské vůbec a v zemi české zvlášť1875monograph/pageuuid:34f65bc0-6d52-11de-9cc7-000d606f5dc6
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Beylage zur Brünner Zeitung29.10.1808periodical/periodicalvolume/supplement/pageuuid:40d23930-7bf1-11e2-b930-005056827e51
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Učebné listy jazyka anglického pro samouky1886monograph/monographunit/pageuuid:55367630-80c8-11dd-b860-000d606f5dc6
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Hospodář: týdenník věnovaný rolnictví, hospodářskému průmyslu a národnímu hospodářství : týdenník věnovaný rolnictví, hospodářskému průmyslu, národnímu hospodářství a veřejné správě vůbec9.4.1887periodical/periodicalvolume/periodicalitem/pageuuid:0c579719-c6f8-4a16-8a4f-c6b12e6d449b
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Fysika pro vyšší školy1870monograph/pageuuid:7141d2c0-e6f8-11dd-a324-000d606f5dc6

LibGen

AuthorTitlePublishedmd5

Archive (50)

TitleDescriptionPublishedAdded
GERMANY TRIED DEMOCRACY19632025-05-22T19:43:23Z
Key monuments of the history of art19512025-09-10T01:40:18Z
Various Artists * 33,333 Steps To A Power Ov The Darkness LeaguesVarious Artists * 33,333 Steps to a Power ov the Darkness Leagues   (Disc one)   01. DJ R3V3R3ND MURD3R * !33,333 STEPS TO A POWER OV THE DARKNESS LEAGUES!  02. sOuL_sCientiSt * More Fiyah Mix   03. FIGURATIVE THEATRE * MEGAMARKET UTOPIA   04. Hel.Razor * Slave 2 The System  05. dreDDup * We Fuck Until Dawn  06. Moray Eel * Hellish Adoption   07. Cryogenic Implosion * Delete Humanity   08. The Apocryphal Order * Beyond The Depraved Scope Of Salvation  09. Come To My Rise * Play A Game  10. The Rinn * Voices  11. Crimson Blue * L.M.A.  12. Severed Fifth * Blackening   13. Spiritual Dissection * Across A Frozen Hell  14. Returning We Hear the Larks * Nascence in the Caverns of Mount Olympus  15. Cuntworm * Seduced By Damnation  16. Earslaughter * Roka Smrti   (Disc two)     01. DiSloCaTed * Megazord  02. Cyber Snake * War  03. Circlerun * 13  04. Obsidian Shell * Misanthropia  05. Dawn Of Tears * Since They're Gone   06. Operación Mutante * Matanza  0;20132013-11-26T13:29:39Z
Soil and freshwater niematodes19512025-09-08T04:35:20Z
Desiree19532025-09-10T01:42:33Z
CDK-11A-M Manual ()2021-03-04T12:02:56Z
The Secret History19902025-08-28T15:24:39Z
MysteryMystery by Cdk & Marc Amiga 4-channel module (MOD module, original file Amiga - MYSTERY.MOD. ) · 4:51 Cdk Marc Tracker type: Amiga 4-channel module Format: MOD Duration: 4:51 Tempo: 125.06 BPM (measured automatically) Plays on ericade.radio: 276 Added to the station: 2022-03-16 00:27:21 Loudness (integrated): -16.5 LUFS Loudness range: 4.4 LU True peak: -3.7 dBTP Dynamic range: DR 10 MP3: 192 kbit/s, 44100 Hz, 2 ch Files in this item: the MP3 as played on the station, the original tracker module, a PDF of the track's profile page, the station's audio analysis and waveform picture, and the complete API record (JSON). Track profile: https://radio.ericade.net/profiles/song/10527/mystery On ericade.radio: https://ericade.radio/song/10527/mystery-cdk-and-marc-of-sonority-productions About the station ericade.radio is The ERICADE Radio Network: an internet radio station streaming tracked music, chiptunes and demoscene music around the clock, with shows and podcasts about retro computing, re;2026-10-08T09:20:23Z
Jay Kay Collision Center, Inc. v. CDK Global, LLCThis item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly.2024-06-27T09:15:55Z
Curses Development KitCDK contains 21 ready-to-use widgets. The package includes a text entry field, a scrolling list, a selection list, an alphalist, pull-down menu, radio list, viewer widget, dialog box and much more.19992004-11-02T15:40:28Z
Marine molluscan genera of western north america19632025-09-08T08:50:24Z
Immunohistochemical characterization of cyclin dependent kinase-4 in different histological grades of oral leukoplakia and oral squamous cell carcinoma.This article is from Journal of Oral and Maxillofacial Pathology : JOMFP , volume 18 . Abstract Background:: Cyclin dependent kinase-4 (CDK4) encoded by CDK gene, is a heterodimer protein of cell cycle in G1-S transition. This study aimed to characterize the CDK4 immunoreactivity in different histological grades of oral leukoplakias (OLs) and oral squamous cell carcinomas (OSCCs) and also aims to discuss its probable role in the tumor biogenesis. Materials and Methods:: Expression of CDK4 was investigated in total of 52 samples including OL (15), OSCCs (30) and normal oral tissues (07). A labeled Streptavidin-Biotin immunohistochemistry assay was performed and staining intensity was evaluated. Results:: The staining pattern was similar in all tissues and was located in both nuclei and cytoplasm. Dysplastic epithelium displayed a progressive increase in nuclear expression of CDK4 when compared to normal tissues. Also, positive staining cytoplasm was highly evident in OSCC with loss of d;20142014-10-21T00:20:34Z
Founders of american economic thought and policy19582025-09-08T05:32:17Z
The Basic College Of Michigan State19552025-09-12T17:56:25Z
The microwave convection cookbook19892025-09-10T00:55:05Z
treatment of the child in emotional conflict19622025-09-04T03:35:05Z
Ik zie je wel, ik hoor je wel20032023-02-23T18:46:56Z
Self Defence Spray VS Dumbass596,872 views Jul 14, 2016   No description has been added to this video.20162025-07-21T09:27:23Z
A life apart: a pilot study of residential institutions for the physically handicapped and the young chronic sick19792024-11-27T21:44:03Z
[CDK 024] DextroidDexter is a Game Boy musician straight outta Southampton, and he’s decided to grace CDKr with his debut album – a pretty intense 15 tracks of musical fun! He’s definitely a chipmusician going places, don’t be surprised to see this guy making it MASSEEV in chiptune, fo sho.20082019-12-07T00:28:52Z
At-home dumbbell workout - Seated Curls20202022-08-11T20:02:13Z
yahoo-groups-2018-02-16T17-40-24Z-2a39a8Yahoo! Groups API grab. Contains messages of the following groups: 2605cotevertu acuradeals adm_fimi aec_mca03_06 aikido_ntu alexsol10 analise_imagens_uff_2006_2 ape_rubd arh_2_2006 aseanclub azin84y bgtennis bipl blufferm bmwreardrivefailures bni_mdtp1_2006 bored_marriedwives botolphclub bszd-1998 caerphillyrfc campanhabira ccegrade9 ccrsgroupe cdk_kouchankap cedarkey centreregionale cgr_1 chat_encantos chepkero cma_oab_ba coolest_tambayan coolgroup_sift coordenadoresdopme cps_nwohio csfb1985 dcacrocks dc_gitu_loh degrassi_juniorhigh diskusi_linux dispagweb_up dmt-2006 ebpls ecell_07organizers egcgraduates_2006 fatec_jd2 fccrc-core foda_uncisal forsa_fcri funny_farm_canasta funzoo_06zlsmc garrickclassof99 gestao_ensp_2006 ghotoentribune gk-lasalle grapevines_senior groupedeschamberland gupo121 guys4hunt helpmakeindia heroicguys homesweethomecooks iac_fpif icfai_bbsr icup_breena iipm_ugp_06-09 incbgm_alumni indiancouples_uae infinity-fahrenheit_international info_i invisibal_view irani;2018-02-16T17:40:32Z
Zen and the birds of appetite19682025-09-30T16:31:29Z
DTIC ADA354074: Cell Cycle in Normal and Malignant Breast Epithelial Cells.Breast cancer is a disease where breast epithelial cells become refractory to appropriate growth and differentiation signals. It is likely that numerous genetic changes can contribute to malignant transformation, including mutations that alter the cell cycle regulatory machinery. We have therefore sought to characterize the function of both positive and negative cell cycle regulatory elements in normal and malignant breast epithelial cells. In particular, we have focused on cyclin E, a positive cell cycle regulators element already implicated in some breast malignancies and on a class of negative regulators of cyclin-dependent kinases (Cdks). Preliminary data indicate that both cylin E and Cdk inhibitors are important in breast malignancy.19982018-04-19T20:58:06Z
DTIC ADA392349: Action of the p53 Effector, p21, on its Targets: Cyclin-cdk and PCNACy or RXL motifs have been previously shown to be cyclin binding motifs found in a wide range of cyclin-cdk interacting proteins. For both cyclin A/cdk2 and cyclin E/cdk2, the presence of a Cy motif decreased the Km(sup peptide! 75 to 120-fold while the kcat remained unchanged. Changes in the length of the linker between the Cy motif and the phosphoacceptor serine suggest that both sites are engaged simultaneously to the cyclin and the cdk, respectively. PS100, a peptide containing a Cy motif, acts as a competitive inhibitor of cyclin/cdk complexes with a 15-fold lower Ki for cyclin E/cdk2 than for cyclin A/cdk2. These results provide kinetic proof that a Cy motif located at a minimal distance from the SPXK is essential for optimal phosphorylation by cdks and suggest that small chemicals that mimic the Cy motif would be specific inhibitors of substrate recognition by cyclin-dependent kinases. In addition, a detailed mutagenesis approach to define what sequence serves as a Cy motif reve;20002018-05-03T14:38:06Z
Exome sequencing reveals a potential mutational trajectory and treatments for a specific pancreatic cancer patient.This article is from OncoTargets and therapy , volume 7 . Abstract Pancreatic cancer is the fourth biggest killer, and has one of the worst prognoses, of any cancer type. Approximately 95% of patients diagnosed with pancreatic cancer will not survive beyond 5 years post diagnosis, and these statistics have barely improved in over 40 years. Here, genomic changes in one particular patient with stage IV metastatic pancreatic cancer were explored to suggest a potential personalized treatment. In particular, exome sequencing of genomic DNA extracted from blood and the cancer biopsy was utilized with the aim of identifying mutational drivers of the cancer. This analysis revealed a splice site mutation in RBCK1 as the most promising driver of the cancer and a therapy based on a pan-cyclin-dependent kinase (pan-CDK) inhibitor, flavopiridol. This study suggests that drugs whose effectiveness is unclear for general populations of cancer sufferers should possibly be reconsidered for specific pati;20142014-10-22T18:42:34Z
Knocking down CDK4 mediates the elevation of let-7c suppressing cell growth in nasopharyngeal carcinoma.This article is from BMC Cancer , volume 14 . Abstract Background: CDK4 is a protein kinase in the CDK family important for G1/S phase cell cycle progression. However, the roles and molecular mechanisms of CDK4 triggering nasopharynx carcinogenesis are still unclear. Methods: Lentiviral-vector mediated shRNA was used to suppress CDK4 expression and examine its molecular mechanisms. Using immunohistochemistry, we analyzed CDK4 protein expression in clinicopathologically characterized nasopharyngeal carcinoma (NPC) cases and nasopharyngeal tissues (NPs). Survival curves were plotted by the Kaplan-Meier method and compared using the log-rank test. Results: In this investigation, we knocked down CDK4 expression and observed that NPC cell growth and cell cycle progression were significantly blocked by suppressing expression of CCND1, CDK6, and E2F1 as well as elevated p21 expression. Further, we found that reduced CDK4 expression elevated the expression of let-7c, a tumor-suppressive miRNA ;20142014-10-22T19:29:11Z
DTIC ADA392324: Isolation of Proteins Interacting With the Cyclin D1-CDK6 Complex From Normal and Tumorigenic Human Breast Cells Using a Novel Yeast Three-Hybrid SystemThe eukaryotic cell division cycle is primary controlled by a family of protein serine/threonine kinases, the cyclin-dependent-kinases (CDKs). Activation of CDKs is dependent upon the interaction with an activating cyclin subunit. Presumably, these kinases progress the cell cycle by phosphorylation of critical cellular proteins. The detection of these transient kinase-substrate protein-protein interactions using conventional methods presents a major technical challenge, and is primarily responsible for our poor understanding of CDK substrates. The yeast two-hybrid system is a method for detecting protein-protein interactions. A major limitation of this method is the fact that only binary interactions can be detected. Using a modified version of the two-hybrid system, I am able to detect the interaction of ternary protein complexes. Using the cyclin D1-CDK6 protein complex as bait, I have identified the interaction of this complex with the tumor suppressor protein tuberin. Tuberin inter;19992018-05-03T14:23:38Z
The King of Fighters 2002: (BR) Tosh-AM-666 vs(BR) [CDK]A.J.KOF - 2022-09-23 17:42:03(BR) Tosh-AM-666 vs (BR) [CDK]A.J.KOF - 2022-09-23 17:42:03 Fightcade replay id: 1663954923376-8072 #fightcade #kof2002 #[CDK]A.J.KOF #Tosh-AM-666 For more videos check out: https://fightcadevids.com2022-09-24T00:59:37Z
Finite element methods for Navier-Stokes equations : theory and algorithmsx, 374 p. : 24 cm // Extended version of: Finite element approximation of the Navier-Stokes equations. 1979 // Bibliography: p. [368]-371 // Includes indexes19862023-12-22T11:10:09Z
homebrew-cdk2021-08-15T04:48:17Z
The Life of Jonathan M. Bennett- A Study of the Virginias In Transition19432023-12-22T16:18:38Z
the new testament19372025-06-17T00:05:16Z
The evolution of plants, (Added t.-p.: Home university library of modern knowledge. New York, H. Holt and Company)19112024-08-07T12:23:24Z
CKD (28648)CDK logo20122021-04-02T02:54:24Z
Paediatric Nursing Procedures19642025-09-08T03:37:07Z
EP 12: Kelsey Smith - Abducted In Broad DaylightKelsey Smith was just 18 years old when she was abducted from a Target parking lot in Overland Park, Kansas in June 2007. Finding her would take a battle with a cellular phone company and heartbreaking surveillance video from Target, that shows that no one is ever really safe, even if you're running a simple errand in broad daylight. A special thank you to Kelsey's mom, Missey Smith, for speaking with me for this episode. To learn more about the Kelsey Smith Foundation and the Kelsey Smith Act, please visit kelseysarmy.org. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode:    - Summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/cdk/13112    - Like Music (cdk Mix) by c;20172023-07-08T12:40:23Z
History of Nursing Source Book19572025-09-04T03:29:44Z
github.com-angular-components_-_2021-03-13_17-17-56Component infrastructure and Material Design components for Angular Official components for Angular The Angular team builds and maintains both common UI components and tools to help you build yourown custom components. The team maintains several npm packages. | Package | Description | Docs || ------------------------- | ----------------------------------------------------------------------------------- | ---------------- || @angular/cdk | Library that helps you author custom UI components with common interaction patterns | Docs || @angular/material | Material Design UI components for Angular applications | Docs || @angular/google-maps | Angular components built on top of the Google Maps JavaScript API | Docs || @angular/youtube-player | Angular component built on top of the YouTube Player API | Docs | Quick links Documentation, demos, and guides | Frequently Asked Questions | Community Google group | Contributing | StackBlitz Template Getting started See our Getting Started Guide if yo;20212021-03-13T21:27:21Z
coderedfm04072020your weekly drum&bass radioshow outta stuttgart / germany2020-07-05T18:29:06Z
CDK Global LLC v. Mark BrnovichThis item represents an oral argument audio file as scraped from a U.S. Government website by Free Law Project.2021-02-06T19:46:12Z
Cell cycle control : mechanisms and controlxii, 402 p. : 24 cm // Includes bibliographical references and index // Cell cycle molecules and mechanisms of the budding and fission yeasts / Tim Humphrey and Amanda Pearce -- The plant cell cycle : an overview / John H. Doonan -- The C. elegans cell cycle / Sander van den Heuvel -- Developmental control of growth and cell cycle progression in drosophila / Lisa Swanhart, Jeremy Kupsco, and Robert J. Duronio -- The xenopus cell cycle : an overview / Anna Philpott and P. Renee Yew -- The mammalian cell cycle : an overview / Jane V. Harper and Gavin Brooks -- Synchronization of cell populations in G1/S and G2/M phases of the cell cycle / Jane V. Harper -- Mapping origins of DNA replication in eukaryotes / Susan A. Gerbi -- In situ assay for analyzing the chromatin binding of proteins in fission yeast / Stephen E. Kearsey ... [et al.] -- Application of magnetic beads to purify cells transiently transfected with plasmids encoding short hairpin RNAs / Peter D. Adams -- The cell cycle and v;20052020-05-25T23:53:12Z
Cell cycle control : mechanisms and protocolsIncludes bibliographical references and index // Cell cycle molecules and mechanisms of the budding and fission yeasts / Tim Humphrey and Amanda Pearce -- The plant cell cycle / John H. Doonan -- The C. elegans cell cycle / Sander van den Heuvel -- Developmental control of growth and cell cycle progression in drosophila / Lisa Swanhart, Jeremy Kupsco, and Robert J. Duronio -- The xenopus cell cycle / Anna Philpott and P. Renee Yew -- The mammalian cell cycle / Jane Vera Harper and Gavin Brooks -- Synchronization of cell populations in G1/S and G2/M phases of the cell cycle / Jane Vera Harper -- Mapping origins of DNA replication in eukaryotes / Susan A. Gerbi -- In situ assay for analyzing the chromatin binding of proteins in fission yeast / Stephen E. Kearsey ... [et al.] -- Application of magnetic beads to purify cells transiently transfected with plasmids encoding short hairpin RNAs / Peter D. Adams -- The cell cycle and virus infection / Steven Emmett ... [et al.] --^ // Methods fo;20052012-05-22T14:15:36Z
Shaping he Future Of Child Health: Challenges For Nurses20002025-08-28T19:09:24Z
CIA Reading Room cia-rdp75-00149r000500450023-6: MR. KENNEDY AND THE CUBA BRIEFINGSTAT Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 25 YEAR RF. RFviFXnil Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 STAT F-a d STAT " Mr. Kennedy. and the CubaBriefin V~~r~ ql cdk Otl,ar MAK Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 i liu,b,2 Pres1&nt .Kennedy's con- tention that he was not, in- formed during the 1960 cam- paign that the Eisenhower administration was sponsor- ing training of Cubans for a possible later invasion to at- tempt to overthrow Castro is one of the most astonish- ing announcements to come ;role the White House under any President in many years. - The President contends that he was not told of the training of Cubans in the U.S. until after he was elect- ed. He carried out the in- vasion under. his own plan- ning after becoming Presi- dent -- in a, manner that Mr. Kennedy's contention was made public by his Chief Press Secretary, Pierre Sal- inger, in respon;19622025-05-16T03:48:08Z
Ep 35: The Case of the Alleged Real-Life Gone GirlA 29-year-old woman goes missing in Vallejo, California in 2015, and the details surrounding her disappearance are bizarre, to say the least. There are many things in this case that may surprise you and have you thinking that you know what's going on....until you don't.  Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music in this episode: Three kites circling by Axletree - http://freemusicarchive.org/music/Axletree/Cormorant_EP/Three_kites_circling a letter from doxent by Stefan Kartenberg - http://dig.ccmixter.org/files/JeffSpeed68/51322 Celestial Navigation by Blue Dot Sessions - http://freemusicarchive.org/music/Blue_Dot_Sessions/Aeronaut/Celestial_Navigation Someday I'll like you but before let me rest in my solitude (Lonely character's theme) by Komiku - http://freemusicarchive.o;20172023-05-31T20:57:33Z
recent advances in soviet science19612025-09-04T05:06:30Z
Sainte-Beuve sa vie et son temps19522025-09-08T01:26:24Z
CDK modulation coordinates G1 events after S phase.This article is from Cell Cycle , volume 13 . Abstract None20142014-10-23T18:29:12Z
A Data-Driven, Mathematical Model of Mammalian Cell Cycle Regulation.This article is from PLoS ONE , volume 9 . Abstract Few of >150 published cell cycle modeling efforts use significant levels of data for tuning and validation. This reflects the difficultly to generate correlated quantitative data, and it points out a critical uncertainty in modeling efforts. To develop a data-driven model of cell cycle regulation, we used contiguous, dynamic measurements over two time scales (minutes and hours) calculated from static multiparametric cytometry data. The approach provided expression profiles of cyclin A2, cyclin B1, and phospho-S10-histone H3. The model was built by integrating and modifying two previously published models such that the model outputs for cyclins A and B fit cyclin expression measurements and the activation of B cyclin/Cdk1 coincided with phosphorylation of histone H3. The model depends on Cdh1-regulated cyclin degradation during G1, regulation of B cyclin/Cdk1 activity by cyclin A/Cdk via Wee1, and transcriptional control of the mitotic;20142014-10-22T18:28:08Z