| Title | Description | Published | Added |
| The pageant of Japanese history, | | 1938 | 2023-07-28T12:19:13Z |
| Authenticom, Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-03-25T23:18:28Z |
| Northtown Automotive Companies Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-03-22T03:31:21Z |
| PAVILIONS PF PROTECTION | | 2006 | 2025-08-21T02:47:59Z |
| Mannen Med Salgpiporna | | 1960 | 2025-09-26T02:02:52Z |
| Flight Without Power | | 1940 | 2025-09-12T12:32:24Z |
| Aviles v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2024-06-28T09:07:16Z |
| [CDK 046] Derris Kharlan - Live | [CDK 046] Derris Kharlan - Live | 2010 | 2020-01-05T19:34:51Z |
| [CDK 060] Whitely - Mori | [CDK 060] Whitely - Mori | 2013 | 2020-01-05T21:26:29Z |
| [CDK 031] One Channel Only | Various Artists - One Channel Only | 2008 | 2019-12-30T21:40:40Z |
| The Future of Public Access TV and The Internet | Mark Cooper of the Consumer Federation of America speaks with local independent radio host John Grebe about current bills in Congress affecting the future of Public Access Television and the Internet. We also hear from Jason Crow, Access Coordinator of Cambridge Community Television and Michael Eisenmenger of Manhattan Neighborhood Network about how pending legislation in Congress takes away local control of media and places more power in the hands of Big Cable and Telephone companies. Click here to listen to the ACMEBoston Podcast February 11, 2006. Also discussed is the issue of Network Neutrality which Free Press , the national media reform organization, describes as "the guiding principle of the Internet that fosters open competition and innovation, while preserving the independence and accessibility of the World Wide Web" - Free Press, Net Freedom Now . To take a closer look at these issues, we'll hear John Grebe's interview from his program, "Sounds of Dissent" broadcast live on ; | 2006 | 2006-07-27T08:21:29Z |
| Armadura Cast #1 - As tantas emoções do EVO 2017 com Tokido & cia | E chegamos com uma novidade. Se a internet e a vida não trollar, deu Armadura Cast estará por aqui batendo ponto. E para começarmos vamos falar sobre o EVO 2017 , afinal, o torneio trouxe de tudo um pouco. Anúncios surpreendentes, grandes finais, história gigantes sendo escritas nas finais. Vamos soltar o play , pera, quadro errado. Nesse episódio: Um pouco sobre o EVO 2017; Dragon Ball FighterZ; Animevo; Finais dos torneios que assistimos; A saga do Tokido. `Playlist: cdk - Once Again (Original RumbleStep Mix) (feat AnalogByNature) Sturzstrom - Brief Physical Patch of Skye Astral - Echo (feat infaredhaze) Olenergy - Double Dragon JupiterSkydive - What a Bitch (feat Ms. Muthafukkin Vybe (Kendra)) gigert9 - Brake (feat Andres Franco) Astral - Astral Travel Stefan Kartenberg - No One's Keeping Score (feat Thespinwires) Stefan Kartenberg - Reckless (feat Thespinwires) Siobhan Dakay - You Believed It Yourself (feat Fluffy) Alex - Where You Are Now (feat WolfFly) TheDI; | | 2017-10-17T03:16:17Z |
| Ultimate Mortal Kombat 3: (BR) [CDK]-heldinho vs(BR) [CDK]-Chakality - 2022-04-03 01:22:00 | (BR) [CDK]-heldinho vs (BR) [CDK]-Chakality - 2022-04-03 01:22:00 Fightcade replay id: 1648948920772-7644 #fightcade #umk3 #[CDK]-heldinho #[CDK]-Chakality For more videos check out: https://fightcadevids.com | | 2022-07-24T22:02:35Z |
| Street Fighter Alpha 2 (960430 USA): (BR) [CDK]-Shaka vs(BR) SweetG - 2022-08-22 04:08:29 | (BR) [CDK]-Shaka (Rank D) vs (BR) SweetG C - 2022-08-22 04:08:29 Fightcade replay id: 1661141309737-2933 0:00 Ryu vs Sagat 02:38 Ryu vs Dan 04:15 Dan vs Sagat 06:25 Evil Ryu vs Dan 08:19 Dan vs Zangief #fightcade #sfa2u #0:06:25 #[CDK]-Shaka #SweetG #0:08:19 #Sagat #Zangief #0:02:38 #0:00:10 #Dan #0:04:15 For more videos check out: https://fightcadevids.com | | 2023-01-23T15:42:54Z |
| CDK Global Holdings, LLC v. Tekion Corp. | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2025-02-11T10:29:53Z |
| MolClass: a web portal to interrogate diverse small molecule screen datasets with different computational models. | This article is from Bioinformatics , volume 28 . Abstract Summary: The MolClass toolkit and data portal generate computational models from user-defined small molecule datasets based on structural features identified in hit and non-hit molecules in different screens. Each new model is applied to all datasets in the database to classify compound specificity. MolClass thus defines a likelihood value for each compound entry and creates an activity fingerprint across diverse sets of screens. MolClass uses a variety of machine-learning methods to find molecular patterns and can therefore also assign a priori predictions of bioactivities for previously untested molecules. The power of the MolClass resource will grow as a function of the number of screens deposited in the database.Availability and implementation: The MolClass webportal, software package and source code are freely available for non-commercial use at http://tyerslab.bio.ed.ac.uk/molclass. A MolClass tutorial and a guide on how ; | 2012 | 2014-10-29T06:43:56Z |
| Historic Preservation Awards 2013 | | 2013 | 2016-10-07T01:03:50Z |
| Serious Pursuits: Vol. III: Communications and Education (Collected Essays of Asa Briggs, Vol 3) | | 1991 | 2023-10-02T01:45:15Z |
| The Osborne/McGraw-Hill CP/M-86 user's guide | viii, 568 p. : 24 cm // On t.p. the registered trademark symbol "R" is superscript following "86" in the title // Includes index | 1985 | 2023-12-22T13:18:25Z |
| Laraqua's Masks Of Nyarlathotep Prologue | The prologue for my Masks of Nyarlathotep solo game designed to get the protagonist to New York ready for the Half-Moon Cult adventure followed by Masks itself. More information on the campaign can be found, including Easter Eggs during the various sessions and a little context, can be found under the Masks of Nyarlathotep tag on http://stwildonroleplaying.blogspot.com.au/ The opening music is CDK's Sunday Sunrise which is Creative Commons (Attribution 3.0) and can be found at http://ccmixter.org/files/cdk/13613 Episode 3's subway soundtrack is Public Domain material which can be found at the Soundbible at http://soundbible.com/386-Riding-NYC-Subway-Car.html | 2013 | 2013-11-24T21:58:36Z |
| Bob Baker Volkswagen v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2018-09-16T22:44:00Z |
| acculturation in the americas | | 1952 | 2025-06-17T03:22:59Z |
| Psychology of Personal Adjustment Student's Introduction to Mental Hygience | | 1949 | 2025-09-10T00:53:02Z |
| George D. Manderbach, Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2025-06-17T09:33:57Z |
| Jane Eyre | | 1960 | 2025-10-09T06:38:41Z |
| eBookMan.cdk | eBookman Content Developer Kit (CDK) multiple releases The CDK has not yet been tested. Compiled by members of the Bookman Archive site . | | 2022-01-13T11:19:46Z |
| Street Fighter Alpha 2 (960430 USA): (BR) [CDK]-Shaka vs(BR) bolsonarominas - 2022-05-29 17:47:42 | (BR) [CDK]-Shaka (Rank D) vs (BR) bolsonarominas D - 2022-05-29 17:47:42 Fightcade replay id: 1653846462940-3572 0:00 Ryu vs Dan #fightcade #sfa2u #0:00:06 #bolsonarominas #Dan #[CDK]-Shaka For more videos check out: https://fightcadevids.com | | 2023-01-23T15:42:44Z |
| Red Ribbon on a White Horse | | 1950 | 2023-07-25T03:47:12Z |
| the student's chronological new testament | | 1904 | 2025-06-16T06:50:48Z |
| The Courtesy Book | | 1927 | 2024-06-27T03:16:26Z |
| Collections of the Massachusetts Historical Society | | 1871 | 2025-09-08T01:09:01Z |
| THE EMPRESS FREDERICK | | 1956 | 2025-05-22T18:23:01Z |
| Sunday morning music thomas dorsey gospel | Sunday morning music thomas dorsey gospel: Make a distinction between saturday night and sunday morning music does not know saintsandsinners music does not know the say from the damn music just knows this is how i feel. | 2022 | 2022-06-09T15:33:01Z |
| Check-List of Birds of the World, Volume I | | 1931 | 2023-07-29T04:45:01Z |
| CDK 01 20 | 01*200 | | 2023-03-23T13:43:39Z |
| Fishing the Pacific, offshore and on | | 1953 | 2023-10-02T17:37:40Z |
| The reason you can't buy a car is the same reason that your health insurer let hackers dox you | This week on my podcast, I read The reason you can't buy a car is the same reason that your health insurer let hackers dox you , a column from one of last week's editions of my Pluralistic newsletter; it describes a monopoly pattern whereby companies execute a series of mergers to dominate a sector, leaving their IT systems brittle and tangled - and vital to the nation. Just like with Equifax, the 737 Max disasters tipped Boeing into a string of increasingly grim catastrophes. Each fresh disaster landed with the grim inevitability of your general contractor texting you that he's just opened up your ceiling and discovered that all your joists had rotted out – and that he won't be able to deal with that until he deals with the termites he found last week, and that they'll have to wait until he gets to the cracks in the foundation slab from the week before, and that those will have to wait until he gets to the asbestos he just discovered in the walls. Drip, drip, drip, as you realize th; | 2024 | 2024-06-30T21:51:55Z |
| Pride Flag Raised in Silver Spring | Montgomery County celebrates Pride Month Music provided by Manhattan Production Music. Montgomery Community Media (MCM) is the only independent, nonprofit organization providing access to public media (public access television and broadband media) directly to Montgomery County’s over one million residents as well as the resident non-profit organizations, associations and businesses. We engage, educate and empower individuals and the community to express diverse viewpoints. Stay up to date on news in Montgomery County! » Subscribe to MCM here: https://goo.gl/fi9sqQ » Check out MCM for more: https://www.mymcmedia.org Follow MCM on these platforms! » Facebook: https://goo.gl/89YTJN » Twitter: https://twitter.com/mymcmedia » Instagram: https://goo.gl/BkuFnD For more Montgomery County, Maryland residents can tune to Comcast channels 21 and 995 | 2022 | 2022-06-02T01:32:19Z |
| In the Path of Mahatma Gandi | | 1950 | 2025-08-23T20:29:24Z |
| DTIC ADA453395: Suppression of Prostate Cancer by PTEN and p18INK4c | The Rb pathway suppresses tumorigenesis by constraining G1 cell cycle progression. Functional inactivation or reduction of this pathway is a common event found in many types of human tumors. To test how the Rb pathway interacts with other cellular pathways in tumor suppression, we characterized mice with combined mutations in the CDK inhibitor p18 (exp Ink4c) and the lipid phosphatase PTEN, which regulates cell growth and survival. The p18(exp -/-) ; PTEN (exp +/-) double mutant mice develop prostate cancer in the anterior and dorsolateral lobes and thyroid C-cell tumors with nearly complete penetrance, and pituitary tumors in both the anterior and intermediate lobes. AKT/PKB, an oncoprotein and downstream substrate of PTEN, was activated and accumulated at the plasma membrane in PTEN (exp +/-) cells, and further activated and accumulated in the nucleus in p18 (exp -/-) ; PTEN (exp +/-) tumor cells, suggesting a tissue- and genetic background-dependent haploinsufficiency of Pten in tum; | 2006 | 2018-06-05T18:22:11Z |
| DTIC ADA300399: Functions of Wild-Type and Mutant Forms of p53 in Breast Cancer. | Cells induced to accumulate the p53 tumor suppressor protein have been shown to arrest in G1. This arrest is characterized by accumulation of the cyclin dependent kinase (CDK) inhibitor p2l (WAF1/CIP1) and of underphosphorylated forms of retinoblastoma protein (pRB). We show here that accumulation of the wild-type pS3 protein in either human or murine cells markedly increases expression of cyclin Dl. The induction of cyclin Dl can also be mediated by a target of p53, the p21 (WAF1/CIP1) inhibitor of cyclin-dependent kinases. The relationship between the induction of cyclin Dl and G1 arrest defines a new cellular response to p53. | 1995 | 2018-03-24T09:25:56Z |
| DTIC ADA398199: Regulation of Ubiquitin Mediated Proteolysis of G1 Cyclins and the CDK Inhibitor p27 by the Cullin Gene Family in Normal Tumorigenic Human Breast Cells | Ubiquitin-mediated proteolysis of cyclins, cyclin-dependent kinase inhibitors and certain other substrates, including proteins whose degradation is necessary for progression through mitosis, provide a molecular basis for unidirectional progression through the eukaryotic cell cycle. Aberrations in the ubiquitin-mediated destruction pathways, and particularly in the destruction of the Dl cyclin, have been implicated in human breast cancer. A cascade of enzymes leads to ubiquitination of substrate: El enzyme (ubiquitin activating); E2 enzyme (ubiquitin conjugating), and E3 enzyme (ubiquitin ligase). This last class of enzyme is large, and it performs the functions of targeting substrate and catalyzing formation of the polvubiquitin chains that mark substrate for destruction. We have found that all three members of the yeast cullin family are capable of performing the ubiquitination activity of E3 enzyme. All three yeast cullins undergo covalent modification with Rub1 protein, presumably t; | 2001 | 2018-05-05T21:00:08Z |
| DTIC ADA412793: Chemotherapy of Late Stage Breast Cancer Targeted Towards Cell Cycle Regulatory Components | Our original goal was to target cell cycle regulatory components as a potential therapy for breast cancer. The target p16 is a tumor suppressor and a CDK inhibitor and is inactivated by gene methylation. The drug 5-aza-2'deoxycytidine (5-Aza-CdR), an inhibitor of DNA methylation, is targeted for reexpression of a repressed p16 in late stage breast cancer patients. Re-activation of the p16 gene in cells in which the gene is methylated will restore normal growth control and be efficacious in treatment of breast cancer. A mouse model for the action of the drug was developed and used to test the efficacy of the drug. | 2002 | 2018-05-12T16:53:07Z |
| The King of Fighters 2002: (BR) LZO//GOIANO CAPOEIRA vs(BR) [CDK]-Shaka - 2022-12-26 14:01:27 | (BR) LZO//GOIANO CAPOEIRA vs (BR) [CDK]-Shaka - 2022-12-26 14:01:27 Fightcade replay id: 1672063287929-7484 #fightcade #kof2002 #LZO//GOIANOCAPOEIRA #[CDK]-Shaka For more videos check out: https://fightcadevids.com | | 2022-12-28T21:17:04Z |
| DTRASH10 - Bastards United - Bastards United | This is a killer collection of breakneck headbanger digital thrash music. Bastards United have are a complete digicore band with guitarists, MCs and program thrashers. Straight from the Netherlands, BU collaborates on some slammin' tracks with Rabies/CDK and b57 from CPUWAR in the mix! | 1999 | 2008-04-19T16:24:14Z |
| Het Utrechts Archief 168792 | Het Utrechts Archief catalog number: 168792 Description (Dutch): Afbeelding van een gezelschap op het 4e perron van het N.S.-station Rotterdam C.S. te Rotterdam, bij het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het betreft hier een gezelschap uit een extra trein voor de Handelsmaatschappij R.S. Stokvis en Zonen. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610). | 1961 | 2021-02-05T03:16:03Z |
| DTIC ADA382749: Resistance to Tamoxifen: A Consequence of Altered p27Kipl Regulation During Breast Cancer Progression | This grant addresses the molecular mechanisms of resistance to the anti-estrogen, Tamoxifen, in breast cancers. Both estrogens and antiestrogens influence the cell cycle during the GI phase. In breast tumors, loss of the cdk inhibitor, p27, is associated with a poor prognosis and with steroid resistance. We postulate that altered p27 degradation in breast cancer may contribute to resistance to antiestrogen therapy. In the last year, we have assayed cell cycle effects of estradiol in the ER+ breast cancer cell line, MCF-7. MCF-7 arrests in G1 upon removal of estradiol or on addition of Tamoxifen. Upon re-addition of estradiol, cells re-enter the cell cycle with onset of S phase by 12 hours and loss of both p21 and p27 proteins. Cyclin D1 associated kinase activity rose transiently in early G1. Activation of cyclin E/cdk2 kinase in mid-late G1 was accompanied by loss of cyclin E-associated p21 and p27. The requirement for p27 in the quiescence induced by estradiol depletion was investiga; | 1999 | 2018-04-29T17:57:19Z |
| DTIC ADA430444: Targeting the AP-1 Transcription Factor for the Treatment of Breast Cancer | The AP-1 transcription factor is a central component of many signal transduction pathways. We have shown that blocking AP-1 by over-expressing a dominant negative form of cJun (cjun-DN, Tam67) inhibits breast cancer cell growth. We hypothesize that inhibition of AP-1 blocks the cell cycle, suppression of AP-1 in vivo inhibits the development of breast tumors, the cjun-DN protein binds and inactivates important growth regulatory proteins present in breast cancer cells, these proteins include Jun and Fos family members as well as coactivators that bind cJun. In the present study, we demonstrated that TAM67 inhibits breast cancer growth both in vitro and in vivo. We determined the mechanism by which AP-1 blockade inhibits breast cancer growth. Our studies suggested that TAM67 inhibits breast cancer growth predominantly by inducing CDK inhibitors ?such as P27), suppressing G1 cyclins expression and reducing CDKs activity, thus inducing a cell cycle block. We also showed that TAM67 binds al; | 2004 | 2018-05-23T22:15:58Z |
| DTIC ADA386459: Action of the p53 Effector, p21, on its Targets: Cyclin-CDK & PCNA | Our aim is to dissect the interactions of p21 (a downstream effector of the tumor suppressor protein p53) with its targets, cyclin-cdks and PCNA. In year 2 we have focused on the cyclin-cdks. We have quantitated the contribution of the cyclin-cdks binding Cy motif (on cdk substrates) to their interaction with the cyclin-cdks. We find that a Cy motif improves the Km of a substrate by 5OO-1000 fold without any effect on the Vmax of the peptide or the Km of ATP. Such a large contribution of the Cy motif to substrate recognition explains why a peptide based on the Cy motif of p21 inhibits phosphorylation by cdk. A small chemical that mimics the structure of the Cy motif would be a specific inhibitor of cdks and suppress breast cancer cell growth. Towards this end, site directed mutagenesis has been used to generate a library of mutants in the Cy motif of p21. Using this library we find that the first arginine (R1) and the third leucine (L3) of the Cy motif (RRLFG) are critical for docking ; | 1999 | 2018-04-30T22:37:50Z |
| Generating comparative analysis of early stage prediction of Chronic Kidney Disease | Chronic Kidney Disease prediction is one of the most important issues in medical decision making. The discovery of ckd prediction is an important task because it depends on experts of doctor knowledge. Construct effective ckd prediction in time is essential to prevent healthy patients. Chronic kidney disease is one of the leading cause of death and early prediction of chronic kidney disease is important. Prediction is most interesting and challenging tasks in day to life. Data mining play a essential role for prediction of medical dataset. It extract unknown information from hidden knowledge. This paper can proposed a new chronic kidney disease dataset with three classifiers such as radial basis function network, multilayer perceptron, and logistic regression. The obtained result of this experiment shows in terms of prediction accuracy, type I error, type II error, type I error rate, type II error rate, sensitivity, specificity, F-score. Kappa value represents that measure of agreement; | 2015 | 2015-10-26T06:47:28Z |