| Title | Description | Published | Added |
| Human Geography An Ecological Study of Society | | 1948 | 2025-09-10T04:44:00Z |
| DR. IDA - THE INSPIRING STORY OF DR. IDA SCUDDER, FIFTY YEARS A MEDICAL MISSIONARY IN INDIA. | | 1959 | 2023-12-29T19:48:32Z |
| The pageant of Japanese history, | | 1938 | 2023-07-28T12:19:13Z |
| A surgeon remembers | | 1953 | 2023-12-22T18:53:56Z |
| Authenticom, Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-03-25T23:18:28Z |
| le mouvement baptiste en palestine et syrie | | 1935 | 2025-06-16T22:29:54Z |
| Northtown Automotive Companies Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2020-03-22T03:31:21Z |
| the new testament | | 1937 | 2025-06-17T00:05:16Z |
| PAVILIONS PF PROTECTION | | 2006 | 2025-08-21T02:47:59Z |
| Het Utrechts Archief 807112 | Het Utrechts Archief catalog number: 807112 Description (Dutch): Afbeelding van het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610). Het treinstel werd voornamelijk gebruikt voor het vervoer van het Concertgebouworkest. | 1960 | 2021-02-03T04:46:45Z |
| Mannen Med Salgpiporna | | 1960 | 2025-09-26T02:02:52Z |
| Education and society in modern Germany | | 1949 | 2023-07-25T04:04:04Z |
| Research in physiology | | 1971 | 2025-09-08T00:26:07Z |
| Scientists In Organizations | | 1966 | 2025-09-11T18:21:23Z |
| De Racine Au Parthenon: Essais Sur La Litterature Et L'Art A L'age Classique | | 1977 | 2025-09-04T14:43:38Z |
| George G. Manderbach, Inc. v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2024-07-16T09:08:36Z |
| Flight Without Power | | 1940 | 2025-09-12T12:32:24Z |
| ginerbreadman | ginerbreadman | | 2022-11-15T19:45:05Z |
| East McComb Body Shop v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2024-08-28T09:13:51Z |
| From this day forward | | 1941 | 2023-07-29T05:57:44Z |
| Aviles v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. If you wish to see the entire case, please consult PACER directly. | | 2024-06-28T09:07:16Z |
| Faust : drame fantastique en cinq actes, quatorze tableaux | 25 p. ; 31 cm // "Représenté pour la première fois, à Paris, sur le Théâtre de la Porte-Saint-Martin, le 27 septembre 1856." | 1912 | 2023-08-09T19:28:32Z |
| Introduction to the textual criticism of the greek | | 1938 | 2025-05-22T16:59:52Z |
| At-home dumbbell workout - Seated Curls | | 2020 | 2022-08-11T20:02:13Z |
| github.com-sindresorhus-awesome_-_2021-09-29_09-07-55 | 😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab, GitHub, and Bitbucket, Gitpod au; | 2021 | 2021-10-02T03:15:21Z |
| CIA Reading Room cia-rdp75-00149r000500450023-6: MR. KENNEDY AND THE CUBA BRIEFING | STAT Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 25 YEAR RF. RFviFXnil Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 STAT F-a d STAT " Mr. Kennedy. and the CubaBriefin V~~r~ ql cdk Otl,ar MAK Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 i liu,b,2 Pres1&nt .Kennedy's con- tention that he was not, in- formed during the 1960 cam- paign that the Eisenhower administration was sponsor- ing training of Cubans for a possible later invasion to at- tempt to overthrow Castro is one of the most astonish- ing announcements to come ;role the White House under any President in many years. - The President contends that he was not told of the training of Cubans in the U.S. until after he was elect- ed. He carried out the in- vasion under. his own plan- ning after becoming Presi- dent -- in a, manner that Mr. Kennedy's contention was made public by his Chief Press Secretary, Pierre Sal- inger, in respon; | 1962 | 2025-05-16T03:48:08Z |
| github.com-TinkoffCreditSystems-taiga-ui_-_2021-01-16_06-32-09 | Angular UI Kit and components library for awesome people Taiga UI Website • Documentation • CDK Wiki • Core team Taiga UI is fully-treeshakable Angular UI Kit consisting of multiple base libraries and several add-ons. It is based on ng-polymorpheus dynamic content approach and uses Web APIs for Angular for required browser APIs. Why Taiga UI 🧩 Modular and fully-treeshakable. We harnessed the power of Secondary Entry Points mechanism. You can import even just one entity from our library and be sure that there is no redundant code in your bundle 🧙 Agnostic . Our components are very flexible and are ready for any use case. But we take care of basic UX aspects to let you focus on your project features 🦋 Customizable . We use CSS custom properties for all our styling and provide easy methods to customize all UI components 🛠 Well engineered . We are not afraid of DI, all our components use OnPush and the whole project is developed with strict TypeScript mode 📦 It's big! ; | 2021 | 2021-01-16T15:23:57Z |
| [CDK 063] The Tin Foil Hat Brigade - Serious Musician | Unrequited love, the frustrations of modern life, Scallies shouting abuse at women from cars - The Tin Foil Hat Brigade talks about these, and more - all within a ten-minute blast of furious Game Boy noise and raw, emotional vocals. Or something like that, anyway. All Music and Lyrics by The Tin Foil Hat Brigade. Recorded and Mastered by Lloyd Gabriel. Additional Vocals (on G.Y.R.O) by Simon Patrick Gabriel and Lloyd Gabriel. Artwork and Photography by Simon Thelwell - http://www.sixeightthree.com/ | 2014 | 2020-01-09T22:58:35Z |
| Shadow of Fu Manchu, | | 1948 | 2023-07-25T02:48:30Z |
| Die Russen | | 1976 | 2025-09-08T18:17:06Z |
| DTIC ADA316821: Cellular Proteins Interacting with the Tumor Suppressor Protein p53. | Tumor suppressor protein p53 interacts directly with the DNA replication factor RPA and inhibits its ability to bind single-strand-DNA. We defined the domain of p53 that bound to RPA and constructed p53 mutants that failed to bind RPA, but still functioned as transcriptional activators. We found that while these mutants of p53 lost their ability to bind RPA; they still maintained the growth suppression function of p53. Growth suppression function of p53 is dependent on its transactivation activity, probably by inducing p21 and other cell cycle inhibitors. We have extended our study to the p2l protein, which is induced by p53 and interacts with both the cdk2 Icinase and a DNA replication factor PcNA. Here we have demonstrated the importance of PCNA-inhibitory domain of p21 in vivo. We have also shown that p21 has to interact directly with both cyclin subunit and cdk2 subunit of the cyclin-cdk complex in order to inhibit the kinase activity and suppress cell growth in vivo. | 1996 | 2018-04-03T17:57:56Z |
| The mystery of baptism | | 1901 | 2025-05-22T17:56:48Z |
| DTIC ADA359281: Role of the Cdk Inhibitor Sic 1 in Start | Mpst cells have four fundamental goals; they must replicate their DNA, segregate their chromosomes, double their mass, and divide. Coordination of these events is essential. I have used the budding yeast S. cerevisiae to dissect the molecular events that control cell cycle progression. I have shown that not only are G1 cyclin-CDK complexes highly unstable rate-limiting activators for cell cycle progression, but that their essential function is to regulate the initiation of DNA replication by phosphorylating and promoting the degradation of a key cell cycle inhibitor, Sic1 (1,2). In fact, cyclin-CDK-regulated proteolysis may constitute the major mechanism of cell cycle control (3). Moreover, Sic1 appears to be the analog of the RB tumor suppressor gene. I have shown that Sic1, like RB, controls the timing of S-phase, ensures genomic stability, and most significantly, sic1 deletions, like rb deletions, completely remove cell cycle dependence on G1 cyclins (1,22). Furthermore, Sic1 protei; | 1998 | 2018-04-21T20:11:43Z |
| CKD (28648) | CDK logo | 2012 | 2021-04-02T02:54:24Z |
| DTIC ADA435854: The Role of Ubiquitin E3 Ligase SCFSKP2 in Prostate Cancer Development | The CDK inhibitor p27Kipl acts as a negative regulator in the cell cycle and in prostate tumorigenesis. Either the loss of p27 or over-expression of its key regulator ubiquitin E3 ligase SKP2 is associated with prostate cancer. Prostate-sepcific expression of SKP2 is sufficient to induce hyperplasia, displasia, and low grade carcinoma in the mouse prostate gland. We propose to examine whether SKP2 cooperates with or is regulated by tumor suppressors such as Pten or Nkx3.1 implicated in prostatic tumorigenesis. In the past year, we have initiated the experiments by breeding and expansion of the colonies, crossing the SKP2 transgenic mice into Pten +/- strains, and ordering Nkx3.1 mice. Compound mice of SKP2 transgene and Pten +/- were made. Our initial studies suggest that there i&. no substantial difference in tumor frequency and grade in the SKP2 and Pten +/- compound mice versus single genetic alterations. These results suggest that PTEN may act through SKP2 for tumorigenesis. Since ; | 2005 | 2018-05-27T08:46:56Z |
| DTIC ADA455296: Consequences of Cyclin D1/BRCA1 Interaction in Breast Cancer Progression | The inheritance of one defective BRCA1 or BRCA2 allele predisposes an individual to developing breast, ovarian and T-cell cancers. In addition, in breast cancers where BRCA1 is not mutated, it is often functionally inactivated. Furthermore, cyclin D1 has been shown to be overexpressed in many cancers including breast cancer and its associates with BRCA1. Because of the crucial role of both of these proteins in cancer, it is reasonable to expect that this interaction has a significant role in tumor cells. The understanding of when this interaction occurs during cell cycle progression will help to determine the role of cyclin D1/BRCA1 binding in breast cancer cells. Therefore, I hypothesize that the direct interaction of cyclin D1 with BRCA1 results in the cell cycle dependent regulation of the activity of BRCA1. In this study, I wish to identify and confirm the cell cycle dependent cyclin D1/BRCA1 interaction in breast cancer cells, determine the biochemical consequence of cyclin D1/BRC; | 2006 | 2018-06-07T00:13:22Z |
| DTIC ADA378108: Role of the Cdk Inhibitor Sic 1 in Start | Nearly 180,000 women will develop breast cancer in 1999 and 44,000 will die. Cancer is essentially a disease of inappropriate proliferation due to a loss of normal cell cycle controls. We study cell cycle controls in the budding yeast S. cerevisiae. We have shown that the formation of active G1-cyclin dependent kinase complexes (Cdks) is rate limiting for cell cycle progression. The activity of these complexes is regulated through their association with highly unstable G1 cyclins. G1 cyclins are constitutively unstable, and their only essential function is to phosphorylate the B-type Cdk inhibitor, Sic1, and target it for degradation. Sic1 is one of few known in vivo substrates of yeast G1-Cdks. The amount and phosphorylation state of Sic1 appears to determine the timing and size of cell division. Sic1 mutants lacking several phosphorylation sites are stabilized and completely block cell cycle progression. Thus, the phosphorylation and subsequent degradation of Sic1 appears to be the c; | 1999 | 2018-04-28T13:18:00Z |
| IUMA: ballantine skuadra | Todo Partio por el año 98', cuando se conocieron Knowman y Black Market. Paso el tiempo y fueron formando distintos grupos (BLG, AGS, CDK), hasta que el 2002 dieron en el clavo creando la BALLANTINE'SKUADRA (un poco en broma, un poco en realidad), con el tiempo fue tomando fuerza e integrando a mas personajes. Un "gancho" en esa creación fue God Killah quien tenia una larga amistad con Get Killah, y este con Dj Killah. Al mismo tiempo otra amistad de antaño es la de God Killah y Glace one, lo que facilito la union entre todos (God Killah conocio hace muchos años a Black Market jejeje.). Get Killah con God Killah, hicieron el primer tema con el respaldo de Dj Killah. Se fueron creando distintas formulas, muchas practicas, todo para obtener el sonido que tenemos. La BTS como cada uno tubo un "comenzar" diferente, tienen muchos estilos y muchas influencias, esta mescla es la que le da el "toque". Los estudios son Black Label Studios a cargo de Dj Killah y la colaboración de los demas; | | 2012-05-16T19:45:45Z |
| DTIC ADA474451: Mechanism of Antineoplastic Action of Bisperoxovanadium Compound | This work describes studies into the mechanism of action of bisperoxovanadium (bpVs) compounds and into the basic biology and regulation of Cdc25A phosphatase. The bpVs cause phase-specific cell cycle arrest (G1/S), dose-dependent inhibition of Cdk activity, and persistent Rb hypophosphorylation upon release from serum starvation, consistent with Cdc25A inhibition. Further, they cause p53-independent apoptosis. Oxidative stress and DNA damage do not appear to be involved in their mechanism of action, given that: p53 is not induced by bpV(Me2Phen); p53 and p21 status do not affect IC50; depletion of glutathione or supplementation with antioxidants does not affect IC50, in contrast to other heavy metal-based agents. With respect to regulation, the Cdc25A nuclear localization signal (NLS) was identified and characterized. Data suggest that phosphorylation of S292, adjacent to the NLS, may promote nuclear localization. In the unperturbed cell cycle, S292 phosphorylation, a Chk1/2 target, a; | 2005 | 2018-06-15T10:53:58Z |
| [CDK 016] Flappiest Bits | Awww hells yeah! Jellica, the UK’s answer to goto80 (and IMO, the most underrated chiptuner in the country) kindly gives CDKr his ‘Flappiest Bits’ – an album which is similar to a wedding. How come? As there’s something old, something new, something borrowed, and something blue! (Some old tracks, some new tracks, a few covers and Pull My Nipples Hard , fact fans) Anyway, away with the awful analogies, just kick back and enjoy some fantastic chiptunes ‘n’ VST tracks! And if you like it, purchase his forthcoming miniCD from RetinaScan! The artwork for this is from the supremely talented Raquel Meyers , who also did the fantastic video for Jellica’s “I wld di 4 u” cover . Jellica also runs the UK’s second best chiptune weblabel (after CDKr of course ^_^), Kittenrock ! It’s down at the moment, and more’s the pity. Kittenrock and CDKr are also releasing a split CD-R soon, hopefully before the year is out! | 2008 | 2019-12-06T23:30:08Z |
| [CDK 056] Steady C - He Started It | [CDK 056] Steady C - He Started It | 2011 | 2020-01-05T21:08:08Z |
| [CDK 059] Cerebral Scars - Northern Dancing Town | [CDK 059] Cerebral Scars - Northern Dancing Town | 2012 | 2020-01-05T21:30:32Z |
| DTIC ADA415783: Regulated Transformation of Mammary Epithelial Cells by Transforming Growth Factor Beta 1 | We report that MMTV-DNIIR female mice have accelerated mammary gland differentiation during early pregnancy with impaired development during late pregnancy and lactation followed by delayed post-lactational involution. Mammary tumors, mostly carcinoma in situ, developed spontaneously in the MMTV-DNIIR mice with a long median latency (27.5 months). Invading carcinoma cells in MMTV-DNIIR animals showed loss of DNIIR transgene expression as determined by in situ hybridization. The data indicate that signaling from endogenous TGF-Betas not only plays an important role in normal mammary gland physiology but also can also suppress the early stage of tumor formation and contribute to tumor invasion once carcinomas have developed. The ability of the TGF-beta signaling pathways to inhibit proliferation of many epithelial cells while stimulating proliferation fibroblasts remains a conundrum. We found that the absence of RhoA and p160(ROCK) activity in fibroblastic NIH3T3 cells and its presence i; | 2003 | 2018-05-13T18:21:14Z |
| DTIC ADA482640: Suppression of Prostate Tumors by INK4C and PTEN | Work during this entire funding period thoroughly characterized mutant mice in the cyclin-dependent kinase (CDK) inhibitor p18Ink4c, which causes hyperplastic cell growth in various tissues including the prostate and the lipid phosphatase Pten, which regulates cell growth and is highly associated with the development of human prostate cancer. The first two years of funding were highly productive and resulted in one manuscript publication supporting a functional collaboration between p18Ink4c and Pten in tumor suppression. Both the rate and spectrum of tumor development in the compound mutant mice were substantially accelerated and expanded. Combined genetic, histological, cellular, and biochemical analyses led to four major findings: (i) that p18 and PTEN each have previously unrecognized functions in tumor suppression, such as p18's function in the prostate and anterior lobe of the pituitary and PTEN's function in the pituitary, (ii) that the p18-Pten double mutant mice developed vari; | 2007 | 2018-06-22T04:53:07Z |
| cuu-dinh-ky | | | 2024-04-09T14:17:26Z |
| The Pacific Crest Trail | | 1975 | 2025-08-28T15:16:47Z |
| Collections of the Massachusetts Historical Society | | 1865 | 2025-09-08T02:21:36Z |
| Charles Darwin.: Memorial notices reprinted from "Nature". | | 1882 | 2023-12-21T17:30:58Z |
| Bob Baker Volkswagen v. CDK Global, LLC | This item represents a case in PACER, the U.S. Government's website for federal case data. This information is uploaded quarterly. To see our most recent version please use the source url parameter, linked below. To see the canonical source for this data, please consult PACER directly. | | 2018-09-16T22:44:00Z |
| Proceedungs of the Massachusetts Historical Society | | 1942 | 2025-09-04T03:49:47Z |