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❌ ČDK❌ Archive.org❌ Crossref❌ LibGen❌ CLEAR ALL

Archive (50)

TitleDescriptionPublishedAdded
The three Jameses19622025-05-22T16:21:27Z
Second international meeting of the international society for neurochemistry19692025-09-08T04:17:18Z
Scientists In Organizations19662025-09-11T18:21:23Z
github.com-serverless-stack-serverless-stack_-_2022-02-07_09-07-40💥 SST makes it easy to build serverless apps. Set breakpoints and test your functions locally. https://serverless-stack.com Serverless Stack (SST) is a framework that makes it easy to build serverless apps. It's an extension of AWS CDK and it features: A Live Lambda Development environment Support for setting breakpoints and debugging in VS Code Support for deploying to multiple environments and regions Higher-level constructs designed specifically for serverless apps Zero-config support for JS and TS (using esbuild ), Go, Python, C#, and F# Quick Start Create your first SST app. ```bash Create your app $ npx create-serverless-stack@latest my-sst-app$ cd my-sst-app Start Live Lambda Development $ npx sst start Deploy to prod $ npx sst deploy --stage prod``` Documentation SST docs SST examples Public roadmap Feature requests Contributing to SST Follow us on Twitter and subscribe to our newsletter for updates. About SST We think SST can make it dramatically easier to build serverless ;20222022-02-07T09:45:28Z
github.com-sottlmarek-DevSecOps_-_2022-01-14_09-42-59Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevSecOps scope. Table of Contents Def;20222022-01-14T21:43:52Z
High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a.This article is from Microbiology , volume 158 . Abstract The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry. The rapid increase of resistance to therapeutic agents, as well as the expense of vaccination with live attenuated vaccines, requires the development of new effective treatments for coccidiosis. Because of their key regulatory function in the eukaryotic cell cycle, cyclin-dependent kinases (CDKs) are prominent drug targets. The Eimeria tenella CDC2-related kinase 2 (EtCRK2) is a validated drug target that can be activated in vitro by the CDK activator XlRINGO (Xenopus laevisrapid inducer of G2/M progression in oocytes). Bioinformatics analyses revealed four putative E. tenella cyclins (EtCYCs) that are closely related to cyclins found in the human apicomplexan parasite Plasmodium falciparum. EtCYC3a was cloned, expressed in Escherichia coli and purified in a co;20122014-10-28T23:41:32Z
Applications of the InChI in cheminformatics with the CDK and Bioclipse.This article is from Journal of Cheminformatics , volume 5 . Abstract Background: The InChI algorithms are written in C++ and not available as Java library. Integration into software written in Java therefore requires a bridge between C and Java libraries, provided by the Java Native Interface (JNI) technology. Results: We here describe how the InChI library is used in the Bioclipse workbench and the Chemistry Development Kit (CDK) cheminformatics library. To make this possible, a JNI bridge to the InChI library was developed, JNI-InChI, allowing Java software to access the InChI algorithms. By using this bridge, the CDK project packages the InChI binaries in a module and offers easy access from Java using the CDK API. The Bioclipse project packages and offers InChI as a dynamic OSGi bundle that can easily be used by any OSGi-compliant software, in addition to the regular Java Archive and Maven bundles. Bioclipse itself uses the InChI as a key component and calculates it on the fly whe;20132014-10-27T02:14:25Z
"Prog113_116" 1995 (MeiMei's BBS? Hard Drives)Originally posted to alt.binaries.old.nl by MeiMei. "Varia Prog113_124 txt-files" 1995 <BBS-files> 1995 - 1998 Varia BBS-files "Prog 1995" Varia bbs-files 1995 **************P113************************************************* DLS Update for IBM LAN 4.00 3D Studio Release 4c1 COREL PHOTO GALLERIE: AIR SHOWS AUTODESK ANIMATOR STUDIO FINAL RELEASE August '95 Warp Fixpak #9 Adobe Premiere Music PACK #1 Borland Visual dbase Compiler v5.5 Paradox For Windows 5.0 ARCSERVE NT v2.0 Collabra Share for Win WRKGRP with EXT BACKUP EXEC 7.01 ENTERPRISE EDITION Hotmetal PRO 2.0 HTML PUBLISHING Crystal TOPAS Professional Version 5.0 Snmpc V4.09 NETWORK MANAGMENT SOFTWARE Holkami 2.0 FINAL RELEASE! OS/2 Ver. Speechtranslator English - Hungarian MICRO HOUSE TECHNICAL LIBRARY Netshield From Mcafee From Internet  Protect all servers in your networ MS Windows NT 3.51 Resource Kit Final SB/AWE32/MIDIFULL KIT (C)CREATIVE LABS  Contains many applications from CL, for al Creative Labs products Ascend;19952025-04-26T02:34:46Z
CIA Reading Room cia-rdp91-00403r000200500046-0: FR:BARBIERI R TO:BARDENHEUER PResearch on Vackarmoderle Reaction.Note 11. On the Maolianism of theYormatiou of lutovuul S-,alfur inPolythionic Acid9l, by Ro Barbieri*ITALIANp perlVvI 920, 1%2* 0-6?5NTO 72-12316-07BJuly 72Studleo on the Weakenrodar Reaotion.Note 1. Thiaoulphurie Acids as ProbableIntermediate Produatep by Re Barbieri.ITALIAIT, parp Ricerea Scientifica.Far&a 11, Hendleonti.Vol 2j No 1,, 19620 pp 62-67073July 72investigations of the Reaction H2StSO2Analytical Procedures for Separatingand Breaking Down Maercquantities ofNfur Componanto in Research WithS , by Ro Barbieri*ITALIAN# porp ifigalVol 30, 1960l pp 1509-1517UTO 72-11838-07BJune 72.191 ( [erawl. M2911AVIM, Gliuscme). ami" 63-129098eHiuf['MbaMj. 1. Barbieri, R*AtULYSIS OF ORGANOMETALUC CONIOUNDS. 17. Taghavint, G.DITIMONATES OF RjPbCI AND R2PbC]- f19621.10p.K-H50 K-H121 MOdf M. BaJilgo, U.K -H - 1117IV1aromer,r1 1 - a-V. Kresge-Hooker7YRm Of [U] U, y) 1960, Science Mraryv. 30, no. 12, p. 1963-1968. Associatca, Detroit, Mich.DESCMMRS: 0=1cal andysi;19832026-03-26T07:30:01Z
CIA Reading Room cia-rdp91-00772r000200890017-1: A FR: JOURNAL OF PHYSIQUE ET LE RADI TO: JOURNAL FUR PRAKTISCHE CHEMIEFriu=.;-, by J. 7-van. U11CLASSIM-Dyer,'~ Journal of Phyal-quo et Le Radium. No-----------195'i7-Havy Tr 1.631/091-,127A E- C~Sci V410=10S.-iNb rDie Y90. TM trunaltion 0+---*~ 0:w r, lmdt of flwzt by U. T. Yuwmj14. Lab Igue-Frolow.. 15 pp.J. php. at :nLdlum4Hge 18, 48-P It98 15 dVth;b;r, 3,9'57.AND-tr-33MMA 58-505Sal 5P4 4~eAug 59pI irpriROF YICIHoilin~th hdo ~)y R-, Duverney,de'Physique et le Radium,16.!- 92261509270s611R-383-IqPreliininary;Ebcperiments on Radioactivities Consequentto J~xp.~osioa of Wires Containing D uterim, ByM. Bon~asFRENCH, per, Le Journal de Physique et le Radiixr,, Vol.2XVIII, No 1.0, 1957, PP 5E5-592*JP.RS for Army Rocket wid Guded Missile AAgency$7 SeP~ GOboalwaima Selector far slow Ifeutronsp by 0. GobertpD4 Tap---otp 21 pp.jrvaival dm- !I~T 10 Ruium.Val M 19501, -PP51-A-,wjuts 6.36aLqiulatlona of the Us *am Ymber of NeutronsEmitted by IndWed Flosion of u23tJ by Ifeutrowiof 11F.2 I%Vp by S. Alalse, M. Gaudin, at &I.FRMII., Oarj, Joamal 62 Rtyslque et le Radiu;19832026-03-25T23:48:15Z
CIA Reading Room cia-rdp83m00914r002800040028-2: REQUEST FOR INTERVIEW - JOSEPH FROMM, U.S. NEWS & WORLD REPORTApproved For Relgrase 2007/03123: CIA-RDP83M00914R(~~C~4f~'f OEXA 82-272 MEMORANDUM FOR: Director of Central Intelligence FROM: erector, Office of External Affairs STAT SUBJECT: Request for Interview - Joseph Fromm, U.S. News & World Report 1. Action Requested: Decline an on-the-record interview with Joseph Fromm, U.S. News & World Report. 2. Background: Fromm's telephoned request is based on his impression that you would like to get your views accurately on the public record. He offers a recorded interview with a pre-publication screening opportunity. The subject would be the role of .intelligence and your role in improving it. Joseph Fromm and other reporters met with you at a breakfast meeting at Headquarters in Rpril 1981. 3. Staff Position: Too frequent on-the-record interviews are not consistent with the current low-profile policy. One leads to another. Your recent interview with David Kahn should suffice for awhile, unless you have some special reason for doing another. The DDCI;19822025-02-22T17:14:43Z
[CDK 056] Steady C - He Started It[CDK 056] Steady C - He Started It20112020-01-05T21:08:08Z
github.com-localstack-localstack_-_2023-09-28_16-42-39💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline :zap: Join the LocalStack Insiders program to help us shape the future of LocalStack! Test drive new features & engage in conversations with us so we can learn from your use cases :zap: LocalStack provides an easy-to-use test/mocking framework for developing cloud applications. Overview • Install • Example • Run • Usage • Releases • Contributing 📖 Docs • 💻 Pro version • ☑️ LocalStack coverage Overview LocalStack is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack s;20232023-09-28T16:55:04Z
github.com-sindresorhus-awesome_-_2022-11-15_06-52-04😎 Awesome lists about all kinds of interesting topics Check out my latest app Favorites Widget Call your favorite people directly from the iPhone Lock Screen My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing u;20222022-11-15T10:06:00Z
github.com-sindresorhus-awesome_-_2023-10-26_11-42-32😎 Awesome lists about all kinds of interesting topics Check out my latest app One Task Stop procrastination and get stuff done by focusing on one task at a time My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. API to get search engine results with ease. API to get search engine results with ease. What is an awesome list?     Contribution guide     Creating a list     Twitter     Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Develop;20232023-10-26T13:33:54Z
Flourescent Protein Tracing19622025-09-12T10:44:29Z
CIA Reading Room cia-rdp90-00552r000100550040-8: PANEL FINDS CASEY NOT UNFIT FOR JOBSanitized Copy Approved for Release 2010/07/29: CIA-RDP90-00552R000100550040-8 NEW YORK TIES E, i' i CLE AIPPEA D 2 DECEMBER 1981 C )IN, PAGE' PANEL ~ , "mg a~ ~t~t tbar~rt the public at saon WadDeKI&Y. r. Noyaiban MW the delay wos.d ernmit ? flies UNFIT I$ the m ;" r of tld c xx* atte,e?a 13 members .rno crula not attend today's s tasks aboutbair v3ee-s on the pane 's eaneiusiom, erxd we+ald Per=ft; Mr. Caaay tozs+3ew them, But 'Whole. Situation is Not rroE,a Moynihan mW uttering,' Senator Sa M. a tthhet: ?o"'di of intelligence Director$ ~- ,to on o`r 1he added ;w 1e ji vse,.a, a sms~ ' used to ref 4Z931JAl3331R33i~ grtoi Josepb R BiBea Jr., Demoemt of Deiawere, said in an WASB1NGTa f,13ee. I -The Se stet iota view aZter the m eetin, that be disa.. Select C ommit ee en bMH*mm will geed with the etanmittee's ~? that and has no ham roe William J. Cawy is "mat to aeey-e as m 0'1 bare a very dirfermt V3tw iron rectorof Caatr*i;atailia,estca,seco~rdins that of nay cdk~e es m the ~iZer,'? t;19812025-06-03T23:01:26Z
CIA Reading Room cia-rdp91-00929r000200680025-9: FR:SHUBKIN V.N. TO:SHULISHOVA O.I.- 14 , /.el iconelvto stuat at seem lw V. ov*WAD ,15 P9owns Pori, 1b 3# FM 65# IV WOW$I" 2Z3.1ummemApr 65 7no ?rlIbmis ft no& 206or a* zatw yorms lw To so /0Mdu%,%Tw~m vwo so= tumob ft so ow^ wo WIGNo st3ps~ kl,~oV, ~- -, k L)--um9mAn 6520630quanutatAve Nrtboft la ftWWUWt by Yo So17 vp o--- - vwp &g= UMMW 1b- 3~ X967ioIV? 0JIPMB "3~t. IV SHU6KIAl.2 cumbd4kc ftlime 67 329pM'4-4 7'r-QV'4rtl*S Of DWGIVUlt 4'AtlrAinS Of tl%w 45Vino of vie (.4cm tior~4s (,,orivo siqlax),UY %* F~, Ct 419'it ~*T, v--~Virux %lo it IL66v 17-p 74-76.i. ~~41 ~ ~''Cim"Alrvu f, I 3tiows0~. ( J /' (~. 6 ' ~ /' t"The so-called Homology of Crystals,, by A. V. ShubnikovRUSSIAN, per, Doklady Akadewit Nauk SSSR Vol 88,pp 453-456NAVY/NISC-3346Oct 72Growth ct C4ft*IkUt tV A. V. MuUdkNp V, X.abdull0 -U:WROM ppmo "a cc VWM&A& !=Wamom-Nms To, AW f,~ 4 -, . I r -- , (tic!AVv 4,i*l 1 ~ -swo4w Ge dbs ftugk as"d via llsbr5-1 eusumbohm-Aodk*V&t v IV 91 At 99 pw* It 901 "s 19496or 209-43"-ftota isterimKrArrA-324brek 1970-ft 33Oft L;19832026-04-05T21:18:00Z
github.com-sindresorhus-awesome_-_2021-05-17_17-24-31😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. What is an awesome list?     Contribution guide     Creating a list     Twitter     Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my blog and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Development Environment Entertainment Databases Media Learn Security Content Management Systems Hardware Business ;20212021-05-18T20:47:48Z
github.com-sindresorhus-awesome_-_2022-01-21_21-53-36😎 Awesome lists about all kinds of interesting topics My Actions app is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab;20222022-01-22T00:52:52Z
github.com-sottlmarek-DevSecOps_-_2022-11-04_12-18-33Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Report typos as issue not via PR. Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevS;20222022-11-05T16:23:36Z
github.com-localstack-localstack_-_2022-04-21_22-18-03💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline! LocalStack provides an easy-to-use test/mocking framework for developing Cloud applications. Overview • Install • Example • Run • Usage • Changelog • Contributing – 📖 Docs • 💻 Pro version • ☑️ Feature coverage • 📢 Announcements Overview LocalStack 💻 is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack supports a growing number of AWS services, like AWS Lambda, S3, Dynamodb, Kinesis, SQS, SNS, and many more! The Pro version of LocalStack supports additiona;20222022-04-22T00:42:51Z
Ep 10 Part 2: Kristine Bunch's Struggle For FreedomIn Part 2 of this episode, Kristine and her newly-formed defense team fight to win back her freedom. Armed with advances in fire science, a potential Brady violation, and some shocking revelations about the State's evidence at trial, Kristine and her team fight till the very end. A special thank you to Kristine Bunch for helping me tell her story. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie. Music featured in this episode: Like Music (cdk Mix) by cdk (c) copyright 2015 Licensed under a Creative Commons Attribution Share-Alike  (3.0) license. http://dig.ccmixter.org/files/cdk/48915 Ft: Phasenwandler Homesick (Keymix) by keytronic (c) copyright 2014 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/Keytronic/47457 Ft: Kizzylotus Paper Planes - Durd;20162023-07-08T12:43:12Z
Cell cycle control : mechanisms and controlxii, 402 p. : 24 cm // Includes bibliographical references and index // Cell cycle molecules and mechanisms of the budding and fission yeasts / Tim Humphrey and Amanda Pearce -- The plant cell cycle : an overview / John H. Doonan -- The C. elegans cell cycle / Sander van den Heuvel -- Developmental control of growth and cell cycle progression in drosophila / Lisa Swanhart, Jeremy Kupsco, and Robert J. Duronio -- The xenopus cell cycle : an overview / Anna Philpott and P. Renee Yew -- The mammalian cell cycle : an overview / Jane V. Harper and Gavin Brooks -- Synchronization of cell populations in G1/S and G2/M phases of the cell cycle / Jane V. Harper -- Mapping origins of DNA replication in eukaryotes / Susan A. Gerbi -- In situ assay for analyzing the chromatin binding of proteins in fission yeast / Stephen E. Kearsey ... [et al.] -- Application of magnetic beads to purify cells transiently transfected with plasmids encoding short hairpin RNAs / Peter D. Adams -- The cell cycle and v;20052020-05-25T21:59:48Z
the valaue theory of karl marx19762025-05-22T13:48:47Z
Cyclin K goes with Cdk12 and Cdk13.This article is from Cell Division , volume 7 . Abstract The cyclin-dependent kinases (Cdks) regulate many cellular processes, including the cell cycle, neuronal development, transcription, and posttranscriptional processing. To perform their functions, Cdks bind to specific cyclin subunits to form a functional and active cyclin/Cdk complex. This review is focused on Cyclin K, which was originally considered an alternative subunit of Cdk9, and on its newly identified partners, Cdk12 and Cdk13. We briefly summarize research devoted to each of these proteins. We also discuss the proteins' functions in the regulation of gene expression via the phosphorylation of serine 2 in the C-terminal domain of RNA polymerase II, contributions to the maintenance of genome stability, and roles in the onset of human disease and embryo development.20122014-10-27T22:08:10Z
CIA Reading Room cia-rdp70-00058r000200100098-1: PUZZLING FOREIGN POLICY OF THE U.S.FE.B. 1 51962 Approved For Release 1999/09/'-pQ1 .RDP7 United 8tates'T e ro ruby die has rdad in. hiai iodal ,which goes MO A,maxrlcan w psper. head-- haq~_ Cominunlat lined' :"Vtl~ e d ti 4!- .,stay' cra* e iA- OOMDgiW11'k .. Cdk ? bif thin M4 Ctrants: : thy; ''zi ,e4 tent to foreigh.*ld' anti the Congo Leader:' it erptains ywQ s trong atfr pe Vol" of,A oa Yet the "iJnlt d gat- ' t d f th o re e e o .policies which go along with former . Batista government this vast pone, do. Tf a c$dl 1'9 goal di et .4 Yr t 1 1e pt Victory' )endue B +dk a ltfiil Q d ve tIs at gC'tbe ' muiifng ta11i fir .. < ;thd words et etc. have speeches ' men. _~ e "l ode ?tSat~ snatchesf h p_oeeibie' 14%, Dim kTuubaff~ ~*ent-in the T?os rte 's, the l" rnm #? ant i~ic tltt~aoty.. Vital, i o s e a slat t[1gli,~ ? f i'q~M,' Cato ndgixe ex+~ e s 1$ o bf t 1+ . 'e dl 'iral o 1, + # < Uride*rstar-dstr,~ Ikrta eager ~e~ e td l t ' :thew le' n logs ,tn ezontinq otii rj~Y .# tiYea rioltcy a it izas ttt-t era:.+1e tie; era;19622023-08-06T09:52:48Z
CIA Reading Room cia-rdp91-00929r000200790054-5: FR:YURKOV D.A. TO:YUR JEV V.ner. FIz Tvvrdo&,o TnIAw.. Val I I Vo U~AIPScm ftj-, - doiid ft-atcVol I!, No arcrbardcart or *l,-i '.1r:-IVIV of ALM tku Djp~.ndwwca i5fcir, .4ut A14,*,act yomation an U.0 01,16.-t-4tim Ofw1U) tbe Dapwndanov cf tho !-"to of !)&foctor) the of a ~;~3L;Ll aMth-.1-cetran at~4m, 17 7. S. VaTiln, 7. pata~c--Mr, Ytri4r. lVorlor.0 Tala, 'lol -f- No 1,40AV,&j!'JuU." vi, t~wrrzyperv- Zbw T"b rizp '101 X(YM,, Wo 7t (If FbV-Orvv-~hVol I=,reaeustum or sa"tro" In*/44810"We &OdUU*m, by 2. T&. lubevo 5 pp.MULWO We zbw Sam nal %I XXTUI, so O~ 1VA,pp U"-LVA.Amr bwt et Ptasftv M" - T*eb ftlevia& wt, ft 6S" . PanIrob ~q gr/, 6 f,2.7hc=-,cl,!cL-ic Propertiss of Cd-6b AUoyog byV. A. Yhrkov, X. 1. Alskseywmp 2 pp.RMIAN, per, Zbur Takh I= nso Val Ml; No 4,,Apr 1956,, pp 9U-912.Awr Ust, of PhysSoviet no-"cbftl I so 4~742 9154-A - "IceAug 57The lborav*loozris PropwtUt a tM AllMmft-Cd &M ft.C4# by V. Am Yaxkmp T. V. Iskmam.,4 pp.mnums per# m NVUL I Noun"# VOL Tma, so 1j,IMP pp al-ehopp5"oat 6c / 3 0', /t~~To la;19832026-04-02T13:08:43Z
DTIC ADA357346: Biology of Somatostatin and Somatostatin Receptors in Breast Cancer.Fifty additional primary human breast tumor samples were analysed for SSTR1-5 mRNA and shown to be all receptor positive. Mean SSTR mRNA level was the highest for SSTR3 followed by SSTR1, SSTR2, SSTR5, and SSTR4. Statistical analysis showed a negative correlation between SSTR2 and tumor size, a positive correlation between SSTR2 and estrogen receptors (ER), and a trend towards a positive correlation between SSTR2 and progesterone receptor, SSTR1 and ER, SSTR1 and lymph node status, and SSTR3 and tumor grade. Breast cancer cell lines also expressed multiple SSTR subtypes but the level of receptor expression was less than that in solid tumors. A panel of antibodies against hSSTR1-5 was produced which detected all five SSTR antigens by Western blots and immunocytochemistry. Both analyses showed a correlation between receptor subtype expression at the protein level with SSTR mRNA levels. All five SSTRs inhibited tumor cell growth, SSTR3 by triggering apoptosis, and the remaining four subty;19982018-04-21T02:02:12Z
github.com-sindresorhus-awesome_-_2021-10-03_02-46-40😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab, GitHub, and Bitbucket, Gitpod au;20212021-10-03T03:30:13Z
Teaching and Learning Adolescent Psychiatry19712025-09-26T19:28:34Z
EP 12: Kelsey Smith - Abducted In Broad DaylightKelsey Smith was just 18 years old when she was abducted from a Target parking lot in Overland Park, Kansas in June 2007. Finding her would take a battle with a cellular phone company and heartbreaking surveillance video from Target, that shows that no one is ever really safe, even if you're running a simple errand in broad daylight. A special thank you to Kelsey's mom, Missey Smith, for speaking with me for this episode. To learn more about the Kelsey Smith Foundation and the Kelsey Smith Act, please visit kelseysarmy.org. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode:    - Summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/cdk/13112    - Like Music (cdk Mix) by c;20172023-07-08T12:40:23Z
Christian Initiation the Reformation Period19702025-06-16T04:36:46Z
Het Utrechts Archief 168793Het Utrechts Archief catalog number: 168793 Description (Dutch): Afbeelding van een gezelschap op het 4e perron van het N.S.-station Rotterdam C.S. te Rotterdam, bij het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het betreft hier een gezelschap uit een extra trein voor de Handelsmaatschappij R.S. Stokvis en Zonen. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610).19612021-02-03T11:11:51Z
github.com-serverless-stack-serverless-stack_-_2022-02-06_04-11-10💥 SST makes it easy to build serverless apps. Set breakpoints and test your functions locally. https://serverless-stack.com Serverless Stack (SST) is a framework that makes it easy to build serverless apps. It's an extension of AWS CDK and it features: A Live Lambda Development environment Support for setting breakpoints and debugging in VS Code Support for deploying to multiple environments and regions Higher-level constructs designed specifically for serverless apps Zero-config support for JS and TS (using esbuild ), Go, Python, C#, and F# Quick Start Create your first SST app. ```bash Create your app $ npx create-serverless-stack@latest my-sst-app$ cd my-sst-app Start Live Lambda Development $ npx sst start Deploy to prod $ npx sst deploy --stage prod``` Documentation SST docs SST examples Public roadmap Feature requests Contributing to SST Follow us on Twitter and subscribe to our newsletter for updates. About SST We think SST can make it dramatically easier to build serverless ;20222022-02-06T21:32:41Z
github.com-sottlmarek-DevSecOps_-_2022-01-15_03-45-55Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevSecOps scope. Table of Contents Def;20222022-01-15T10:00:54Z
Novel structural features of CDK inhibition revealed by an ab initio computational method combined with dynamic simulationsThe rational development of specific inhibitors for the ~500 protein kinases encoded in the human genome is impeded by a poor understanding of the structural basis for the activity and selectivity of small molecules that compete for ATP binding. Combining classical dynamic simulations with a novel ab initio computational approach linear-scalable to molecular interactions involving thousands of atoms, we have investigated the binding of five distinct inhibitors to the cyclin-dependent kinase CDK2. We report here that polarization and dynamic hydrogen bonding effects, so far undetected by crystallography, affect both their activity and selectivity. The effects arise from the specific solvation patterns of water molecules in the ATP binding pocket or the intermittent formation of hydrogen bonds during the dynamics of CDK/inhibitor interactions and explain the unexpectedly high potency of certain inhibitors such as 3-(3H-imidazol-4-ylmethylene)-5-methoxy-1,3-dihydro-indol-2-one (SU9516). T;20082013-09-17T19:30:51Z
CIA Reading Room cia-rdp83m00914r002700200048-3: REQUEST FOR SPEAKING ENGAGEMENT - CHIEF EXECUTIVE S FORUM, PALM SPRINGS, CALIFORNIAApproved For Release 2007/03/15: CIA-RDP83M0091 2-fR009g~l~ 3 OEXA 82-0226 MEMORANDUM FOR: Director of Central Intelligence Director, fT-ice o External Affairs STAT SUBJECT: Request for Speaking Engagement - Chief Executive's Forum, Palm Springs, California 1. Action Requested: Regret an invitation to speak to the Chief Executive's Forum in Palm Springs on 21 February. 2. Background: Public Affairs received this invitation by telephone from Leo Greenland, Program Chairman of the Chief Executive's For m. A formal invitation is in the mail. Greenland says you met at home in New York. You are committed to Palm Beach 19-23 February. 3. Recommendation: To ease Greenland's problem in arranging for another speaker, authorize Public Affairs to telephone your regrets. Director of Central Intelligence (Date) /s/ _ - ___ T2- Director of Central Intelligence (Date) STAT STAT OEXA/CEW/cdk/27 Jan 82/x7676 Distribution: Orig - Addressee DDCI - ER 1 - D/OEXA 1 - OEXA Registry 1 - C/PAD (To Be Returned;19822025-02-22T15:15:54Z
github.com-sindresorhus-awesome_-_2022-11-23_17-40-35😎 Awesome lists about all kinds of interesting topics Check out my latest app Favorites Widget Call your favorite people directly from the iPhone Lock Screen My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing u;20222022-11-24T01:59:00Z
DTIC ADA389563: Role of c-Myc in Estrogen Stimulated Cell Proliferation in Normal and Malignant Breast Epithelial CellsEstrogenic steroids have diverse physiological functions and are critically involved in the pathogenesis of breast cancer. The transcriptional regulator c-Myc has been implicated in estrogen-induced mitogenesis and we are therefore investigating the contribution of c-Myc to various downstream molecular and cellular events after estrogen stimulation. Transcriptional activation of c-myc is an early response to estrogen treatment and we have previously shown that induction of c-Myc quantitatively reproduces the effects of estrogen on cell cycle progression. Furthermore, c-Myc induction mimics other downstream effects of estrogen including activation of cyclin E-Cdk2 by decreased association with the CDK inhibitor p2l. Accumulating evidence suggests that the transforming capacity of c-Myc correlates more closely with transcriptional repression than with activation, raising the question of which function is the more important for c-Myc regulation of cell cycle progression. Our ongoing exper;20002018-05-02T06:37:38Z
Shoreline City Council Regular Meeting - December 2, 2024# Shoreline City Council Regular Meeting - December 2, 2024 The Shoreline City Council met on Monday, December 2, 2024, at 7:00 p.m. in the Council Chamber at Shoreline City Hall. The meeting focused on two major study items: the adoption of Ordinance No. 1026 updating the 2024 Comprehensive Plan and Ordinance No. 1027 updating the Zoning Map and Development Code to implement the plan. The council heard extensive public comment, discussed staff presentations, and set the stage for action at the December 16 meeting. ### Consent Calendar - **Approved unanimously (6-0):** The consent calendar included approval of special meeting minutes of November 4, 2024, regular meeting minutes of November 18, 2024, and authorization for the City Manager to execute change orders increasing the contract with CDK Construction Inc. by $850,000 to a maximum of $7,912,540 for the Ballinger Maintenance Facility Project. ### Public Comments & Testimony - **Jill Chapman**, Shoreline resident, expressed concern;20242026-09-03T10:16:24Z
github.com-localstack-localstack_-_2021-11-19_13-25-02💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline! LocalStack provides an easy-to-use test/mocking framework for developing Cloud applications. Overview • Install • Run • Configure • Play – 📖 Docs • 💻 Pro version • ☑️ Feature coverage • 📢 Announcements Overview LocalStack 💻 is a cloud service emulator that runs in a single container on your laptop or in your CI environment.With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider!Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services,LocalStack helps speed up and simplify your testing and development workflow. LocalStack supports a growing number of AWS services, like AWS Lambda, S3, Dynamodb, Kinesis, SQS, SNS, and many more!The Pro version of LocalStack supports additional APIs and advanced features.You c;20212021-11-19T14:17:34Z
github.com-localstack-localstack_-_2023-09-30_18-12-34💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline :zap: Join the LocalStack Insiders program to help us shape the future of LocalStack! Test drive new features & engage in conversations with us so we can learn from your use cases :zap: LocalStack provides an easy-to-use test/mocking framework for developing cloud applications. Overview • Install • Example • Run • Usage • Releases • Contributing 📖 Docs • 💻 Pro version • ☑️ LocalStack coverage Overview LocalStack is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack s;20232023-10-01T06:18:17Z
Plant WEE1 kinase is cell cycle regulated and removed at mitosis via the 26S proteasome machinery.This article is from Journal of Experimental Botany , volume 64 . Abstract In yeasts and animals, premature entry into mitosis is prevented by the inhibitory phosphorylation of cyclin-dependent kinase (CDK) by WEE1 kinase, and, at mitosis, WEE1 protein is removed through the action of the 26S proteasome. Although in higher plants WEE1 function has been confirmed in the DNA replication checkpoint, Arabidopsis wee1 insertion mutants grow normally, and a role for the protein in the G2/M transition during an unperturbed plant cell cycle is yet to be confirmed. Here data are presented showing that the inhibitory effect of WEE1 on CDK activity in tobacco BY-2 cell cultures is cell cycle regulated independently of the DNA replication checkpoint: it is high during S-phase but drops as cells traverse G2 and enter mitosis. To investigate this mechanism further, a yeast two-hybrid screen was undertaken to identify proteins interacting with Arabidopsis WEE1. Three F-box proteins and a subunit of t;20132014-10-23T22:24:00Z
Predict shipment ETA with no-code machine learning using Amazon SageMaker CanvasOver the last few years, online education platforms have seen an increase in adoption of and an uptick in demand for video-based learnings because it offers an effective medium to engage learners. To expand to international markets and address a culturally and linguistically diverse population, businesses are also looking at diversifying their learning offerings by localizing content into multiple languages. These businesses are looking for reliable and cost-effective ways to solve their localization use cases. Localizing content mainly includes translating original voices into new languages and adding visual aids such as subtitles. Traditionally, this process is cost-prohibitive, manual, and takes a lot of time, including working with localization specialists. With the power of AWS machine learning (ML) services such as Amazon Transcribe , Amazon Translate , and Amazon Polly , you can create a viable and a cost-effective localization solution. You can use Amazon Transcribe to create a;20222022-08-10T05:07:03Z
A functional role for Smad7 in sustaining colon cancer cell growth and survival.This article is from Cell Death & Disease , volume 5 . Abstract Initially identified as an inhibitor of transforming growth factor (TGF)-β mainly owing to its ability to bind TGF-β receptor type I and abrogate TGF-β-driven signaling, Smad7 can interact with additional intracellular proteins and regulate TGF-β-independent pathways, thus having a key role in the control of neoplastic processes in various organs. Genome-wide association studies have shown that common alleles of Smad7 influence the risk of colorectal cancer (CRC), even though the contribution of Smad7 in colon carcinogenesis is not fully understood. In this study, we assessed the expression and role of Smad7 in human and mouse models of sporadic CRC. We document a significant increase of Smad7 in human CRC relative to the surrounding nontumor tissues and show that silencing of Smad7 inhibits the growth of CRC cell lines both in vitro and in vivo after transplantation into immunodeficient mice. Knockdown of Smad7 result;20142014-10-24T02:06:36Z
Dual Control of Yen1 Nuclease Activity and Cellular Localization by Cdk and Cdc14 Prevents Genome Instability.This article is from Molecular Cell , volume 54 . Abstract The careful orchestration of cellular events such as DNA replication, repair, and segregation is essential for equal distribution of the duplicated genome into two daughter cells. To ensure that persistent recombination intermediates are resolved prior to cell division, the Yen1 Holliday junction resolvase is activated at anaphase. Here, we show that the master cell-cycle regulators, cyclin-dependent kinase (Cdk) and Cdc14 phosphatase, control the actions of Yen1. During S phase, Cdk-mediated phosphorylation of Yen1 promotes its nuclear exclusion and inhibits catalytic activity by reducing the efficiency of DNA binding. Later in the cell cycle, at anaphase, Cdc14 drives Yen1 dephosphorylation, leading to its nuclear relocalization and enzymatic activation. Using a constitutively activated form of Yen1, we show that uncontrolled Yen1 activity is detrimental to the cell: spatial and temporal restriction of Yen1 protects against g;20142014-10-23T07:40:09Z
Het Utrechts Archief 846447Het Utrechts Archief catalog number: 846447 Description (Dutch): Interieur van het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610). Het treinstel werd voornamelijk gebruikt voor het vervoer van het Concertgebouworkest.19602021-02-27T20:18:20Z
CIA Reading Room cia-rdp66b00403r000100360030-7: DEAR MR. CHAIRMAN:Approved For Release 2005/03/15 : CIA-RDP66B00403R000100360030-7 tb* 3 U 1 e4a b* of **y stan e to you in We at rala+ d "" to C*A s. J S. Ws s Ls1 C 1 OGC / L.C: JOOJ r: cdk 0 & I Addressee I-IG 1 . DD/S I - Comptroiier - Attn: 3 - OGC/LC w/basic iA - Subj. w/basic House Gov't Oper, 1 - Signer - JGOJr. 1 - Chrono. Approved For Release 2005/03/15 : CIA-RDP66B00403R000100360030-7 . -RnPAARQQdQ3RQQQ SENDER WILL CHECK CLASSIFICA ION TOP AND BOTTOM UNCLASSIFIED CONFIDENTIAL SECRET CENTRAL INTELLIGENCE AGENCY OFFICIAL ROUTING SLIP TO NAME AND ADDRESS DATE INITIALS I Le is Counsel 2 DD/Support 3 4 5 6 ACTION DIRECT REPLY PREPARE REPLY APPROVAL DISPATCH RECOMMENDATION COMMENT FILE RETURN CONCURRENCE INFORMATION SIGNATURE Remarks : 1: For information, 2: For action. 00 0UjAIts FOLD HERE TO RE ER FROM: NAME, ADDRESS AN DATE UNCLASSIFIED CONFIDENTIAL SECRET Fo2R 610. 237 Use previous editions Approved For Release 2005/03/15 : CIA-RDP66B00403R000100360030-720052024-05-20T07:03:06Z
github.com-sindresorhus-awesome_-_2022-02-06_04-16-17😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab, GitHub, and Bitbucket, Gitpod au;20222022-02-07T22:05:38Z