| Title | Description | Published | Added |
| The three Jameses | | 1962 | 2025-05-22T16:21:27Z |
| Second international meeting of the international society for neurochemistry | | 1969 | 2025-09-08T04:17:18Z |
| Scientists In Organizations | | 1966 | 2025-09-11T18:21:23Z |
| github.com-serverless-stack-serverless-stack_-_2022-02-07_09-07-40 | 💥 SST makes it easy to build serverless apps. Set breakpoints and test your functions locally. https://serverless-stack.com Serverless Stack (SST) is a framework that makes it easy to build serverless apps. It's an extension of AWS CDK and it features: A Live Lambda Development environment Support for setting breakpoints and debugging in VS Code Support for deploying to multiple environments and regions Higher-level constructs designed specifically for serverless apps Zero-config support for JS and TS (using esbuild ), Go, Python, C#, and F# Quick Start Create your first SST app. ```bash Create your app $ npx create-serverless-stack@latest my-sst-app$ cd my-sst-app Start Live Lambda Development $ npx sst start Deploy to prod $ npx sst deploy --stage prod``` Documentation SST docs SST examples Public roadmap Feature requests Contributing to SST Follow us on Twitter and subscribe to our newsletter for updates. About SST We think SST can make it dramatically easier to build serverless ; | 2022 | 2022-02-07T09:45:28Z |
| github.com-sottlmarek-DevSecOps_-_2022-01-14_09-42-59 | Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevSecOps scope. Table of Contents Def; | 2022 | 2022-01-14T21:43:52Z |
| Zds1 regulates PP2ACdc55 activity and Cdc14 activation during mitotic exit through its Zds_C motif. | This article is from Journal of Cell Science , volume 125 . Abstract At anaphase onset, highly active mitotic cyclin-dependent kinase (Cdk) is inactivated to promote exit from mitosis and completion of cytokinesis. The budding yeast Cdc14p phosphatase is a key mitotic regulator that counteracts cyclin-dependent kinase (Cdk) activity during mitotic exit. Separase, together with Zds1p, promotes the downregulation of the protein phosphatase 2A in conjunction with its Cdc55p regulatory subunit (PP2ACdc55) in early anaphase, enabling accumulation of phosphorylated forms of Net1p and release of Cdc14p from the nucleolus. Here we show that the C-terminal domain of Zds1p, called the Zds_C motif, is required for Zds1-induced release of Cdc14p, and the N-terminal domain of the protein might be involved in regulating this activity. More interestingly, Zds1p physically interacts with Cdc55p, and regulates its localization through the Zds_C motif. Nevertheless, expression of the Zds_C motif at endo; | 2012 | 2014-10-28T00:57:58Z |
| Identification of Genes Interacting with rnt-1 Through Large-Scale RNAi Screening in Caenorhabditis elegans. | This article is from G3: Genes|Genomes|Genetics , volume 3 . Abstract Although many critical roles of the RUNX family proteins have already been identified, little attention has been given to how these proteins interact with other factors. Elucidating RUNX protein interactions will help extend our understanding of their roles in normal development and tumorigenesis. In this study, we performed large-scale RNAi screening to identify genes that genetically interact with rnt-1, the sole homolog of RUNX protein in the nematode Caenorhabditis elegans. To this end, we took advantage of the fact that C. elegans can survive a severe loss of RNT-1 function with only mild phenotypes, and we looked for genes that caused a synthetic phenotype in the rnt-1 mutant background. We identified seven genes, three of which (cdk-8, cic-1, and sur-2) are involved in transcription, two of which (pgp-2 and cct-5) are involved in stress response, and two of which (D2045.7 and W09D10.4) are involved in signalin; | 2013 | 2014-10-28T00:42:20Z |
| Cell cycle control : mechanisms and control | xii, 402 p. : 24 cm // Includes bibliographical references and index // Cell cycle molecules and mechanisms of the budding and fission yeasts / Tim Humphrey and Amanda Pearce -- The plant cell cycle : an overview / John H. Doonan -- The C. elegans cell cycle / Sander van den Heuvel -- Developmental control of growth and cell cycle progression in drosophila / Lisa Swanhart, Jeremy Kupsco, and Robert J. Duronio -- The xenopus cell cycle : an overview / Anna Philpott and P. Renee Yew -- The mammalian cell cycle : an overview / Jane V. Harper and Gavin Brooks -- Synchronization of cell populations in G1/S and G2/M phases of the cell cycle / Jane V. Harper -- Mapping origins of DNA replication in eukaryotes / Susan A. Gerbi -- In situ assay for analyzing the chromatin binding of proteins in fission yeast / Stephen E. Kearsey ... [et al.] -- Application of magnetic beads to purify cells transiently transfected with plasmids encoding short hairpin RNAs / Peter D. Adams -- The cell cycle and v; | 2005 | 2020-05-25T23:53:12Z |
| Retrospectiva 2016 | Foi um ano difícil, mas nós sobrevivemos. Eleve o cosmo e siga o Armadura Nerd: www.armaduranerd.com.br facebook.com/ArmaduraNerd youtube.com/ArmaduraNerd twitter.com/ArmaduraNerd instagram.com/armaduranerd Contato comercial: armaduranerd@gmail.com Trilha sonora do podcast: New York City (Instrumental) by spinningmerkaba (c) copyright 2011 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/jlbrock44/30389 Bad_Attraction by Stefan Kartenberg (c) copyright 2015 Licensed under a Creative Commons Attribution license. http://dig.ccmixter.org/files/JeffSpeed68/48947 Ft: brad sucks The Game Has Changed (cdk RumbleStep Mix) by cdk (c) copyright 2013 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/cdk/41830 Ft: My Free Mickey You Believed It Yourself by Siobhan Dakay (c) copyright 2015 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/SiobhanD/50482 Ft: Fluffy Story; | | 2017-02-05T01:22:06Z |
| Het Utrechts Archief 807112 | Het Utrechts Archief catalog number: 807112 Description (Dutch): Afbeelding van het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610). Het treinstel werd voornamelijk gebruikt voor het vervoer van het Concertgebouworkest. | 1960 | 2021-02-03T04:46:45Z |
| Shoreline City Council Regular Meeting - December 2, 2024 | # Shoreline City Council Regular Meeting - December 2, 2024 The Shoreline City Council met on Monday, December 2, 2024, at 7:00 p.m. in the Council Chamber at Shoreline City Hall. The meeting focused on two major study items: the adoption of Ordinance No. 1026 updating the 2024 Comprehensive Plan and Ordinance No. 1027 updating the Zoning Map and Development Code to implement the plan. The council heard extensive public comment, discussed staff presentations, and set the stage for action at the December 16 meeting. ### Consent Calendar - **Approved unanimously (6-0):** The consent calendar included approval of special meeting minutes of November 4, 2024, regular meeting minutes of November 18, 2024, and authorization for the City Manager to execute change orders increasing the contract with CDK Construction Inc. by $850,000 to a maximum of $7,912,540 for the Ballinger Maintenance Facility Project. ### Public Comments & Testimony - **Jill Chapman**, Shoreline resident, expressed concern; | 2024 | 2026-09-03T10:16:24Z |
| CIA Reading Room cia-rdp83m00914r002900060005-4: I AM PLEASED TO INVITE YOU TO A ONE-DAY SPECIAL SECURITY PRESENTATION | Approved For Release 2006/0 Y2rY A`TR _ 83M00914R002900060005-4 Washington. D. C 20505 31 MAR 1982 ER 82-4708/1 I am pleased to invite you to a one-day-special security pres- entation sponsored by the White House and hosted by the Central Intelligence Agency at n Thursday, 25X1 13 May 1982. This session w i l l give those o you who were unable to attend last year the chance to do so. The schedule is enclosed. This highly-selective session has been designed to meet your special needs as an official Government spokes- person. I promise you it will be interesting and informative. The day is intended to broaden your knowledge and enhance your effective- ness throughout your period of Government service. If my schedule holds, I plan to be with you for at least a portion of the day. Kindly direct your response to CIA's Public Affairs office, telephone 351-7676. I hope to see you there. Sincerely, I g ail William J. Casey Director of Central Intelligence Enclosure UNCLASSIFIED WHEN SEPARATED ; | 1982 | 2024-07-15T20:22:12Z |
| Canonical Non-Homologous End Joining in Mitosis Induces Genome Instability and Is Suppressed by M-phase-Specific Phosphorylation of XRCC4. | This article is from PLoS Genetics , volume 10 . Abstract DNA double-strand breaks (DSBs) can be repaired by one of two major pathways—non-homologous end-joining (NHEJ) and homologous recombination (HR)—depending on whether cells are in G1 or S/G2 phase, respectively. However, the mechanisms of DSB repair during M phase remain largely unclear. In this study, we demonstrate that transient treatment of M-phase cells with the chemotherapeutic topoisomerase inhibitor etoposide induced DSBs that were often associated with anaphase bridge formation and genome instability such as dicentric chromosomes. Although most of the DSBs were carried over into the next G1 phase, some were repaired during M phase. Both NHEJ and HR, in particular NHEJ, promoted anaphase-bridge formation, suggesting that these repair pathways can induce genome instability during M phase. On the other hand, C-terminal-binding protein interacting protein (CtIP) suppressed anaphase bridge formation, implying that CtIP fu; | 2014 | 2014-10-06T07:32:29Z |
| CIA Reading Room cia-rdp91-00772r000100180064-8: A FR: MARINOV, A. I. TO: MARKELOV, I. M. | W(CAd , M. h~ and Properties of Sheets of NowgingSteeip 4ed by Aluminiumo by D. A., LitvinenkovA. 11,Mar ~ v Vo K. Barzy,, V. 1. Yakushin. MCLMM34% Or* stals Wo 10# 1958# PP 931-938.DSIR LLU (loan) )L492ac t MqNtsbl~ 59(SF-1038)Sv,erdlovsk, MR 500 KV Electric-PowerSubstaiion.. by L. D. Gustav., M. I. Levin,A.11M. M''arinov, L. M. Myzin) A. P. Petrokov,12 pp.iRu~SLOTI,, per,, Hlektrichestvo, No 7, 1960,pp 61-6 5.JpRs 4c~oBe16n jKlectric PowerSep 60iFWThe V-ml, Pollilp-o' Sygtmm as of tbm 40th Anniverrmyy ofthn lInvolution by A~ M, fTrangpor,olt an lt~n ~110 v~2-mal "-a Eactric Pover in th!.CF4cct-.Ichcvhlyn StnntEtii, No il,19571,U&9REcon25 Max, J-958BuIWU Vu-Ug the L"t 20 Tears,, by12 ypsWLW~Mo per, bidrolo&Va i Motemologiva#! vca:sorlso :UUP No 4* 1964s pip 19-27.JFIRS Z76A46Sci4kAh ~Wl wid Astron21r,4205vp of tM ItLvoo. in 940W114 byV..,.V Akio lintri-illet-M-300iolto Am M-4Wouls100 by M. lbriww,, 9 pp.m4 pop Glavaomp Vol Vs No 8# BonatAUS 8-U.CILAw u-8471poor 17./,g./C IculiFLLUX-IS; | 1983 | 2026-03-31T10:45:48Z |
| CIA Reading Room cia-rdp85m00364r002204280136-7: LETTER TO (SANITIZED) | Approved For Release 2007/12/19: CIA-RDP85M00364R002204280136-7 CENTRAL INTELLIGENCE AGENCY PUBLIC AFFAIRS Phone: (703) 351-7676 18 April 1983 STAT Thank you for writing Mr. Casey for whom I am responding. I am sorry but the Central Intelligence Agency is in no position to help you. Thank you for writing our Agency. I am sorry we cannot be of assistance to you. Sincerely, STAT OEXA/PAD/KJH/cdk/18 Apr 83/7676 Di strib..a.. __ C/e Pd Approved For Release 2007/12/19: CIA-RDP85M00364R002204280136-7 _ STAT | 1983 | 2025-02-20T13:56:07Z |
| Flourescent Protein Tracing | | 1962 | 2025-09-12T10:44:29Z |
| Pterostilbene Simultaneously Induced G0/G1-Phase Arrest and MAPK-Mediated Mitochondrial-Derived Apoptosis in Human Acute Myeloid Leukemia Cell Lines. | This article is from PLoS ONE , volume 9 . Abstract Background: Pterostilbene (PTER) is a dimethylated analog of the phenolic phytoalexin, resveratrol, with higher anticancer activity in various tumors. Herein, the molecular mechanisms by which PTER exerts its anticancer effects against acute myeloid leukemia (AML) cells were investigated. Methodology and Principal Findings: Results showed that PTER suppressed cell proliferation in various AML cell lines. PTER-induced G0/G1-phase arrest occurred when expressions of cyclin D3 and cyclin-dependent kinase (CDK)2/6 were inhibited. PTER-induced cell apoptosis occurred through activation of caspases-8-9/-3, and a mitochondrial membrane permeabilization (MMP)-dependent pathway. Moreover, treatment of HL-60 cells with PTER induced sustained activation of extracellular signal-regulated kinase (ERK)1/2 and c-Jun N-terminal kinase (JNK)1/2, and inhibition of both MAPKs by their specific inhibitors significantly abolished the PTER-induced activati; | 2014 | 2014-10-06T23:46:41Z |
| Remarkable women of france ( from 1431 to 1749 ) | | 1914 | 2025-09-08T04:07:29Z |
| CIA Reading Room cia-rdp90-00077r000100040018-7: PROCUREMENT DIVISION STATISTICS AND WORKING RELATIONSHIPS WITH OFFICE OF COMMUNICATIONS | Declassified in Part -Sanitized Copy Approved for Release 2012/03/23 :CIA-RDP90-000778000100040018-7 STAT STAT "__""...."., '..,."~??"?` ~wr 27 January 1984 '?(O: Nam ,office symbol, rrrm number, .~, . 1. C/PD/OL L -. p royal s Requested (Coordination REMARKS Preparo Reply See Me The D/L is scheduled to speak to the Office of Communications staff meeting group on 5 March and he would like you to supply him with information and statistics relative to your rev 1 of Su~~ nrt to nr and your view of the workin s~?tion between your office and' Would appreciate your input by 24 Fe ruary. STAT STAT DO NOT uss this foam as a RECORD of approvals, concurrences, disposals. clearances, and similar actions FROM: (Name, org, symbol, Agency/Post) Frankie 0-D/L so4i-ioz _< ~p~ Eby cs~ ev. 76) _.:. f+ GPO , tON~ n _ an~_c~o .,~,. - F~YR [at Cdk~ ~m_~~ ene ~s Declassified in Part -Sanitized Copy Approved for Release 2012/03/23 :CIA-RDP90-00077R0~00100040018-7 Declassified in Part - Sanitized Copy Appr; | 1984 | 2026-04-28T20:15:47Z |
| github.com-DovAmir-awesome-design-patterns_-_2022-10-22_18-36-37 | A curated list of software and architecture related design patterns. Awesome Software and Architectural Design Patterns A curated list of software and architecture related design patterns. Software design pattern - A general, reusable solution to a commonly occurring problem within a given context in software design. It is a description or template for how to solve a problem that can be used in many different situations. Contents Programming language design patterns General Architecture Cloud Architecture Serverless Architecture Micro services & Distributed Systems Internet of things Big Data Databases and storage Docker and DevOps Mobile Front End Development Security Programming Language Design Patterns AngularJS design patterns C# design-patterns design-patterns-for-human - ultra simplified explanation to design patterns. Design Patterns Library C++ design-patterns Closure design-patterns Go design-patterns Java sourcemaking - patterns and anti patterns. oodesign - patterns catalog ; | 2022 | 2022-10-24T11:37:01Z |
| Street Fighter Alpha 2 (960430 USA): (BR) [CDK]-Shaka vs(BR) SweetG - 2022-08-22 04:08:29 | (BR) [CDK]-Shaka (Rank D) vs (BR) SweetG C - 2022-08-22 04:08:29 Fightcade replay id: 1661141309737-2933 0:00 Ryu vs Sagat 02:38 Ryu vs Dan 04:15 Dan vs Sagat 06:25 Evil Ryu vs Dan 08:19 Dan vs Zangief #fightcade #sfa2u #0:06:25 #[CDK]-Shaka #SweetG #0:08:19 #Sagat #Zangief #0:02:38 #0:00:10 #Dan #0:04:15 For more videos check out: https://fightcadevids.com | | 2023-01-23T15:42:54Z |
| CIA Reading Room cia-rdp79-01209a000300030001-3: Weekly Situation Report on International Terrorism | Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 No For Dissem No sem Abroad ontrolled Dissem Weekly Situation Report on International Terrorism 7 November 1973 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300g30D.0.1.:_3.-.-.- -, .a 25X1 C3b2 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Next 11 Page(s) In Document Exempt Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 25X1 C3b2 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Approved For Release 1999/09/21 : CIA-RP? @fn9AO00300030001-3 No Fore'ici.n Dissem/N sem ~Abrocrd/Controlled :Dissem he presumably smuggled aboard,the aircraft in Maracaibo. The hijacker, who is in critical' Condition and not expected to live, apparently wanted to fly to Cuba to live with his par; | 1973 | 2023-06-26T23:01:38Z |
| github.com-sindresorhus-awesome_-_2022-01-21_04-06-07 | 😎 Awesome lists about all kinds of interesting topics My Actions app is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab; | 2022 | 2022-01-21T12:39:20Z |
| A functional role for Smad7 in sustaining colon cancer cell growth and survival. | This article is from Cell Death & Disease , volume 5 . Abstract Initially identified as an inhibitor of transforming growth factor (TGF)-β mainly owing to its ability to bind TGF-β receptor type I and abrogate TGF-β-driven signaling, Smad7 can interact with additional intracellular proteins and regulate TGF-β-independent pathways, thus having a key role in the control of neoplastic processes in various organs. Genome-wide association studies have shown that common alleles of Smad7 influence the risk of colorectal cancer (CRC), even though the contribution of Smad7 in colon carcinogenesis is not fully understood. In this study, we assessed the expression and role of Smad7 in human and mouse models of sporadic CRC. We document a significant increase of Smad7 in human CRC relative to the surrounding nontumor tissues and show that silencing of Smad7 inhibits the growth of CRC cell lines both in vitro and in vivo after transplantation into immunodeficient mice. Knockdown of Smad7 result; | 2014 | 2014-10-24T02:06:36Z |
| github.com-serverless-stack-serverless-stack_-_2022-02-03_19-01-38 | 💥 SST makes it easy to build serverless apps. Set breakpoints and test your functions locally. https://serverless-stack.com Serverless Stack (SST) is a framework that makes it easy to build serverless apps. It's an extension of AWS CDK and it features: A Live Lambda Development environment Support for setting breakpoints and debugging in VS Code Support for deploying to multiple environments and regions Higher-level constructs designed specifically for serverless apps Zero-config support for JS and TS (using esbuild ), Go, Python, C#, and F# Quick Start Create your first SST app. ```bash Create your app $ npx create-serverless-stack@latest my-sst-app$ cd my-sst-app Start Live Lambda Development $ npx sst start Deploy to prod $ npx sst deploy --stage prod``` Documentation SST docs SST examples Public roadmap Feature requests Contributing to SST Follow us on Twitter and subscribe to our newsletter for updates. About SST We think SST can make it dramatically easier to build serverless ; | 2022 | 2022-02-04T20:51:28Z |
| github.com-sindresorhus-awesome_-_2021-04-23_16-56-34 | 😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my blog and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Development Environment Entertainment Databases Media Learn Security Content Management Systems Hardware Business Work Networking Decentralized Systems Higher Education Events Testing Miscellaneous Related Platforms Node.js - Async non-blocking event-driven JavaScript ru; | 2021 | 2021-04-25T20:56:24Z |
| github.com-localstack-localstack_-_2023-09-30_01-52-12 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline :zap: Join the LocalStack Insiders program to help us shape the future of LocalStack! Test drive new features & engage in conversations with us so we can learn from your use cases :zap: LocalStack provides an easy-to-use test/mocking framework for developing cloud applications. Overview • Install • Example • Run • Usage • Releases • Contributing 📖 Docs • 💻 Pro version • ☑️ LocalStack coverage Overview LocalStack is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack s; | 2023 | 2023-09-30T05:53:41Z |
| ＰＨＯＮＫ ＦＲＩＤＡＹＳ | iNFMS - The Don Chronicles pt.1 | PHONK FRIDAY SEASON 3 | Episode 1 --------------------------------------------------------------- Produced by iNFMS | https://infms495.bandcamp.com/ Video Edit by iNFMS chapter 3: 𝖙𝖍𝖊 𝖉𝖔𝖓 𝖈𝖍𝖗𝖔𝖓𝖎𝖈𝖑𝖊𝖘 - [00:20] MAKE SOME ENDZ [03:14] SHE DONT EVEN SMOKE [06:23] ADRENOCHROME [09:48] ADRENOCHROME PT 2 [11:49] 200 THOUSAND ON MY WRIST [15:07] $CREWED UP [17:34] SMOKIN OUT - -special thanks: LORDKADO, STVSHBOI, PXSSXSSXD, BADRADIO and ANALOG BY NATURE - -audio drip: https://soundcloud.com/iaminfms/the-don-chronicles-vol-1 - https://www.analogbynature.tv https://www.badradio.nz Twitter - twitter.com/official_iNFMS Twitch - twitch.tv/analogbynature DLive - https://dlive.tv/cdk - Official Spotify Playlist: https://spoti.fi/2V5Jzqr Join : https://bit.ly/2UIIw08 ▶▶ATTENTION ARTISTS AND PRODUCERS▶▶ ----Submissions: http://bitSubmit.net/21 ---100% Free Music Distribution on spotify , itunes , and more http://www.amuse.io?utm_source=RC ▶▶Co; | 2020 | 2024-02-12T06:19:34Z |
| "Prog113_116" 1995 (MeiMei's BBS? Hard Drives) | Originally posted to alt.binaries.old.nl by MeiMei. "Varia Prog113_124 txt-files" 1995 <BBS-files> 1995 - 1998 Varia BBS-files "Prog 1995" Varia bbs-files 1995 **************P113************************************************* DLS Update for IBM LAN 4.00 3D Studio Release 4c1 COREL PHOTO GALLERIE: AIR SHOWS AUTODESK ANIMATOR STUDIO FINAL RELEASE August '95 Warp Fixpak #9 Adobe Premiere Music PACK #1 Borland Visual dbase Compiler v5.5 Paradox For Windows 5.0 ARCSERVE NT v2.0 Collabra Share for Win WRKGRP with EXT BACKUP EXEC 7.01 ENTERPRISE EDITION Hotmetal PRO 2.0 HTML PUBLISHING Crystal TOPAS Professional Version 5.0 Snmpc V4.09 NETWORK MANAGMENT SOFTWARE Holkami 2.0 FINAL RELEASE! OS/2 Ver. Speechtranslator English - Hungarian MICRO HOUSE TECHNICAL LIBRARY Netshield From Mcafee From Internet Protect all servers in your networ MS Windows NT 3.51 Resource Kit Final SB/AWE32/MIDIFULL KIT (C)CREATIVE LABS Contains many applications from CL, for al Creative Labs products Ascend; | 1995 | 2025-04-26T02:34:46Z |
| Overtures Of Biology | | 1964 | 2025-09-11T12:55:51Z |
| CIA Reading Room cia-rdp91-00403r000200380008-6: FR:IZSO L TO:BAGER G | Traffic Organization and Preparation of Tim Tableofor Pusenger Shippliig on the Balaton.MMGARIANI perk Kozlekedese KozIony) 24 may 1970.,PP 384-387.DTA LN 1328-70Ju1Y 71The Plans and Tasks of Mobart for the Year 1970.RMARIM., per. KozIekedesi Kbzlony, No 16,19 April 1970, p 285.DTA rX 114g-7oJ'AlY 71Trends In Transportmbion and Postal Output Devicing1969.MMGMIM~ perk Kozelekedsi lCozIony, No 153April 12, 1970, p~ M7-2',11.DIA LN 1148-70May 71The Twerity-Five Years of Hungarian Shipping.UMMIM, per, I-a-ziekedesi KoziMp .4 April 1970sPp 248-250-DiA Lw 1147-70State PAIUVWU# IM Task* MftbWobyWay &*Wlo 9 pp.HUWARW Paogo 90 IYAOr 0ins 50417RF,NungaryF400&F ?0 407j,346V^aq;mBow&r 70 4020445NW& 7111 lans for I~ailroad Containerization wotexi.by Laszlo Izao, k~yorgy ionyrd, 9 pp,10WARIAW, por, Xozlq)cedAk 1~q pnv, lWapust,30 I'~ov 1969. pp W~Z~d- L4 _-i ei~s 49688U~ImngaryBconi-eb 70 40o,6o,6-laticnal aid i iiaij)our L,; 40I )ILL.14lUji"'It"L.'j, ~ILEi2!L~ 17 ~.;,),vo, 1'J69Ilil.,\ 1~~ U48-69(D; | 1983 | 2026-03-31T13:43:14Z |
| github.com-lloesche-valheim-server-docker_-_2021-03-12_08-25-55 | Valheim dedicated gameserver with automatic update, World backup and ValheimPlus mod support lloesche/valheim-server Docker image Valheim Server in a Docker Container (with ValheimPlus support) Table of contents Basic Docker Usage Environment Variables Log filters Event hooks Event hook examples Install extra packages Copy backups to another location Delay restarts by 1 minute and notify on Discord ValheimPlus config from Environment Variables System requirements Deployment Deploying with Docker and systemd Deploying with docker-compose Deploying to Kubernetes Deploying to AWS ECS Updates Backups Finding Your Server In-game Steam Server Browser Steam Server Favorites & LAN Play Admin Commands Supervisor Supervisor API Status web server ValheimPlus Updates Configuration Server data rate Disable server password Changing startup CMD in Portainer Synology Help First install Updating the container image to the latest version Error after download of new container image Basic Docker Usage The; | 2021 | 2021-03-15T19:02:56Z |
| github.com-localstack-localstack_-_2022-08-19_11-32-42 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline! LocalStack provides an easy-to-use test/mocking framework for developing Cloud applications. Overview • Install • Example • Run • Usage • Changelog • Contributing – 📖 Docs • 💻 Pro version • ☑️ Feature coverage • 📢 Announcements Overview LocalStack 💻 is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack supports a growing number of AWS services, like AWS Lambda, S3, Dynamodb, Kinesis, SQS, SNS, and many more! The Pro version of LocalStack supports additiona; | 2022 | 2022-08-19T12:35:21Z |
| CIA Reading Room cia-rdp91-00929r000100440035-5: FR:ZAVROV M.I. TO:LAVROVSKIY M.P. | ProNems 0 Thawy 4 P U A 4 0 - W4narum=adon 45yalem of Guidame of AW-AbTrAft ArdbM Fire),by N, F. LAIMRU.~,aMv bk, Kv.~ TouU P U A Z Qm MOSWW*1960. pq 1-Ul -OVTI)--Mi:~~75us"MilApr 65C j 2.=duced in Underarcund OPtniflentiv,x; byLavrovp ct al,Dept of iftUS Bur of VArms~Centrsl ftyer Staft. Ro 342D-6?7 73'by 59XXXZMNLM ACeliMatizaticM of MM3lSrUtl3 IU thtUSSR., by H - P - JAvro _A 150 pp e___yWMIAN, bkl AM] 4 tizatsUa Qmdatry v MR$Isdatellotvo Teentrosoyatao 1957-Dept of UteriorM C3 V 7Sai - Biol 14 k, z a ~?sop 61RusBinn Game Reports. Vol II. Muskrat, 1951-1955.Fluctuations and Forecasts of Muskrat Numbers, byN. F. Levrov.RUSSIAN, per, Voprosy Biologii Pushnykh ?verey iTekhniki Ckhotnichlyego Promysta (USSR), V07 xi-XIV, 1051-1955.Order from Queen's PrinterCanadaSci - BiclJul 59CTS 1, 12Russian Game OReports. Vol II. Muskrat, 1951-10,55.Interiml nnd External Parasites of Muskrats, byN. F. Lavrov.RUSSIPJ;, per, Voprosy Biologii Pushnykh Zverey iTekhniki Oldiotnichlyego Promysta (USSR), V; | 1983 | 2026-04-02T12:22:45Z |
| Het Utrechts Archief 168793 | Het Utrechts Archief catalog number: 168793 Description (Dutch): Afbeelding van een gezelschap op het 4e perron van het N.S.-station Rotterdam C.S. te Rotterdam, bij het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het betreft hier een gezelschap uit een extra trein voor de Handelsmaatschappij R.S. Stokvis en Zonen. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610). | 1961 | 2021-02-03T11:11:51Z |
| CIA Reading Room cia-rdp80-00809a000600200257-6: CHEMISTRY | Sanitized Copy Approved for Release 2011/0(6/29: CIA-RDP80-00809A000600200257-6 PLACE ACQUIRED USSR DATE of TRIMMMON. 194; AENTRAL u' rELUGENCE AGENCY STAT' STAT Or 700 111700 11707" 7117'511 WE 10.10500 or 111E 177101001 007 10 0. t. C_ a1 Me at. 01010.10[0. 77 1100011111am 00 T111 10001707100 OF 111 00/110110 la 011 0.1000 TO .. 01.011007go r11100 11 0110. 010700 11101. 480e100cva1 00 1051 roam I1 roo119700. 001. 0010. 110700107011 co MUD 70 5001 or T01 0010 1001 am 0760t0 01 no to 01C01"" A at a1Ct105Et *0*1*?. AW&s aye' ; '"Wig une LY4/. rugs rer pm .t5Ta3 Translation e requested.) p.rifica]1p THIS IS UNEVALUATED INFORMATION FOR THE RESEARCH USE OF TRAINED INTELLIGENCE ANALYSTS ARMY now of the echenatic Grignard equation, R R > C a o f 111 1' - R- C ..- oLgx, (S) In the irks devoted to the investigation of the mechanism )f ,he Grignard reaction (we have in mind the works of Rees (1), L+eisenheimer (2) 1'feifer and Blank (3), Neen 'anov, A. W. sasonova (4) mid others), the reacti; | 1948 | 2026-05-13T04:59:10Z |
| CIA Reading Room cia-rdp86b00985r000100080009-5: LETTER TO MS. MINNIE REED DIRECTOR OF CAREER SERVICES PRINCETON UNIVERSITY | Approved For lease 2005/07/14: CIA-RDP86B00985~00100080009-5 CENTRAL [iVTl;!_LIGENCE AGENCY' WASHINGTON, A. C. 20505 PUBLIC AFFAIRS 3'hone: (703) 351-767!5 6 November 1981 Ms. Minnie Reed Director of Ca.re~er Services Clio Hall Princeton University Princeton, New Jersey 08544 -Dear Pis . Reed In connectiion with the forthcoming visit of CIA Personnel STAT Officer to Princeton, you have inquired as to the Agency's po icy w~ regard to hiring homosexuals. The CIA selects its employees on the basis ofi professional qualifications and aptitudes alone. Agency employees are entrusted with access to highly sensitive classified information relating to the national security. Consequently, before employment procedures are completed and an employee enters on duty the employee must receive a security clearance. f-or this purpose the employee must be deter-- - mined to be of unquestioned loyalty and.gaod character. Moreover, the employee must be found not likely to?be susceptible to techniques known; | 1981 | 2024-05-13T17:20:36Z |
| 【小迪安全】红蓝对抗 ｜ 网络攻防 ｜ V2023全栈培训-上 | Original URL：https://www.bilibili.com/video/BV12om2YTEgW/ 1. 第1天：基础入门-Web应用&架构搭建&站库分离&路由访问&配置受限&DNS解析 (1:32:47) 2. 第2天：基础入门-Web架构&前后端分离站&Docker容器站&集成软件站&建站分配 (1:39:51) 3. 第3天：基础入门-Web架构&OSS存储&负载均衡&CDN加速&反向代理&WAF防护 (1:28:15) 4. 第4天：基础入门-APP架构&小程序&H5+Vue语言&Web封装&原生开发&Flutter (1:15:44) 5. 第5天：基础入门-反弹SHELL&不回显带外&正反向连接&防火墙出入站&文件下载 (1:44:15) 6. 第6天：基础入门-抓包技术&HTTPS协议&APP&小程序&PC应用&WEB&转发联动 (1:46:25) 7. 第7天：基础入门-抓包技术&全局协议&封包监听&网卡模式&APP&小程序&PC应用 (1:16:53) 8. 第8天：基础入门-算法分析&传输加密&数据格式&密文存储&代码混淆&逆向保护 (1:35:30) 9. 第9天：基础入门-算法逆向&散列对称非对称&JS源码逆向&AES&DE; | 2024 | 2026-06-23T06:15:43Z |
| github.com-sindresorhus-awesome_-_2021-10-03_02-46-40 | 😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab, GitHub, and Bitbucket, Gitpod au; | 2021 | 2021-10-03T03:30:13Z |
| DTIC ADA398172: Role of c-Myc in Estrogen Stimulated Cell Proliferation in Normal and Malignant Breast Epithelial Cells | Estrogenic steroids have diverse physiological functions and are critically involved in the pathogenesis of breast cancer. The transcriptional regulator c-Myc has been implicated in estrogen-induced mitogenesis and we are therefore investigating the contribution of c-Myc to various downstream molecular and cellular events after estrogen stimulation. We have now developed a series of cell lines expressing c-Myc and mutants lacking one or both of the conserved 'Myc boxes' required for transcriptional regulation activity, under the control of an inducible promoter. Ongoing experiments are examining whether these mutants can mimic the effects of estrogen in activating cyclin E-Cdk2 and inducing cell cycle progression. We have recently shown that decreased expression of the CDK inhibitor p21, a c-Myc target, is critical for estrogen activation of cyclin E-Cdk2 and consequently the effect of the c-Myc mutants on p21 expression is of particular interest. We have also shown that decreased c-My; | 2001 | 2018-05-05T20:39:40Z |
| the valaue theory of karl marx | | 1976 | 2025-05-22T13:48:47Z |
| Behind The Scenes and Updates On Each Case | In this episode, I take you behind-the-scenes of each case I covered in the Court Junkie podcast, as well as go over the latest updates. You'll also hear from Pravin Varughese's mom and family friend, as well as other Court Junkies. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode: - Improvisation On Friday... by Alex (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/AlexBeroza/17253 Ft: The3amAssociation - CAliformia Road by dilating_times (c) copyright 2014 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/dilating_times/44880 - summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter; | 2017 | 2023-07-08T12:41:02Z |
| Capsaicin-Induced Apoptosis of FaDu Human Pharyngeal Squamous Carcinoma Cells. | This article is from Yonsei Medical Journal , volume 53 . Abstract Purpose: To investigate the anti-tumor effect of capsaicin on human pharyngeal squamous carcinoma cells (FaDu). Materials and Methods: The expression of apoptosis/cell cycle-related proteins (or genes) was examined by reverse transcriptase-polymerase chain reaction, western blotting and ELISA methods, while the apoptotic cell population, cell morphology and DNA fragmentation levels were assessed using flow cytometry, fluorescence microscopy and agarose gel electrophoresis. Results: Capsaicin was found to inhibit the growth and proliferation of FaDu cells in a dose- and time-dependent manner. Apoptotic cell death was confirmed by observing increases in nuclear condensation, nuclear DNA fragmentation and sub-G1 DNA content. The observed increase in cytosolic cytochrome c, activation of caspase 3 and PARP (p85) levels following capsaicin treatment indicated that the apoptotic response was mitochondrial pathway-dependent. G; | 2012 | 2014-10-24T15:33:22Z |
| Dual Control of Yen1 Nuclease Activity and Cellular Localization by Cdk and Cdc14 Prevents Genome Instability. | This article is from Molecular Cell , volume 54 . Abstract The careful orchestration of cellular events such as DNA replication, repair, and segregation is essential for equal distribution of the duplicated genome into two daughter cells. To ensure that persistent recombination intermediates are resolved prior to cell division, the Yen1 Holliday junction resolvase is activated at anaphase. Here, we show that the master cell-cycle regulators, cyclin-dependent kinase (Cdk) and Cdc14 phosphatase, control the actions of Yen1. During S phase, Cdk-mediated phosphorylation of Yen1 promotes its nuclear exclusion and inhibits catalytic activity by reducing the efficiency of DNA binding. Later in the cell cycle, at anaphase, Cdc14 drives Yen1 dephosphorylation, leading to its nuclear relocalization and enzymatic activation. Using a constitutively activated form of Yen1, we show that uncontrolled Yen1 activity is detrimental to the cell: spatial and temporal restriction of Yen1 protects against g; | 2014 | 2014-10-23T07:40:09Z |
| High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle. | This article is from Oncotarget , volume 5 . Abstract Myc (c-Myc) counteracts p27 effects, and low p27 usually correlates with high Myc expression in human cancer. However there is no information on the co-expression of both genes in chronic lymphocytic leukemia (CLL). We found a lack of correlation between RNA and protein levels of p27 and Myc in CLL cells, so we determined the protein levels by immunoblot in 107 cases of CLL. We observed a high p27 protein expression in CLL compared to normal B cells. Ectopic p27 expression in a CLL-derived cell line resulted in cell death resistance. Surprisingly, Myc expression was very low or undetectable in most CLL cases analyzed, with a clear correlation between high p27 and low Myc protein levels. This was associated with low Skp2 expression, which is consistent with the Skp2 role in p27 degradation and with SKP2 being a Myc target gene. High Myc expression did not correlate with leukemia progression, despite that cell cycle-related Myc target; | 2014 | 2014-10-06T05:32:23Z |
| DTIC ADA398199: Regulation of Ubiquitin Mediated Proteolysis of G1 Cyclins and the CDK Inhibitor p27 by the Cullin Gene Family in Normal Tumorigenic Human Breast Cells | Ubiquitin-mediated proteolysis of cyclins, cyclin-dependent kinase inhibitors and certain other substrates, including proteins whose degradation is necessary for progression through mitosis, provide a molecular basis for unidirectional progression through the eukaryotic cell cycle. Aberrations in the ubiquitin-mediated destruction pathways, and particularly in the destruction of the Dl cyclin, have been implicated in human breast cancer. A cascade of enzymes leads to ubiquitination of substrate: El enzyme (ubiquitin activating); E2 enzyme (ubiquitin conjugating), and E3 enzyme (ubiquitin ligase). This last class of enzyme is large, and it performs the functions of targeting substrate and catalyzing formation of the polvubiquitin chains that mark substrate for destruction. We have found that all three members of the yeast cullin family are capable of performing the ubiquitination activity of E3 enzyme. All three yeast cullins undergo covalent modification with Rub1 protein, presumably t; | 2001 | 2018-05-05T21:00:08Z |
| A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine. | This article is from Oncotarget , volume 5 . Abstract Cdk9 is a key elongation factor for RNA transcription and functions by phosphorylating the C-terminal domain of RNA polymerase II. Here we present direct evidence that cdk9 is important for cancer cell survival and describe the characterization of the potent cdk9 inhibitor CDKI-73 in primary human leukemia cells. CDKI-73 induced caspase-dependent apoptosis that was preceded by dephosphorylation of cdk9 and serine 2 of RNA polymerase II. CDKI-73 was more potent than the pan-cdk inhibitor flavopiridol and showed >200-fold selectivity against primary leukemia cells when compared with normal CD34+ cells. Furthermore, CDKI-73 was equipotent in poor prognostic sub-groups of leukemia patients and showed cytotoxic synergy with the nucleoside analog fludarabine. The Mechanism of synergy was associated with CDKI-73-mediated transcriptional inhibition of MCL1 and XIAP that was maintained when used in combination with fludarabine. Our data pres; | 2013 | 2014-10-23T22:14:55Z |
| Predict shipment ETA with no-code machine learning using Amazon SageMaker Canvas | Over the last few years, online education platforms have seen an increase in adoption of and an uptick in demand for video-based learnings because it offers an effective medium to engage learners. To expand to international markets and address a culturally and linguistically diverse population, businesses are also looking at diversifying their learning offerings by localizing content into multiple languages. These businesses are looking for reliable and cost-effective ways to solve their localization use cases. Localizing content mainly includes translating original voices into new languages and adding visual aids such as subtitles. Traditionally, this process is cost-prohibitive, manual, and takes a lot of time, including working with localization specialists. With the power of AWS machine learning (ML) services such as Amazon Transcribe , Amazon Translate , and Amazon Polly , you can create a viable and a cost-effective localization solution. You can use Amazon Transcribe to create a; | 2022 | 2022-08-10T05:07:03Z |
| vmmo | vjmom m zzmomkqjm rkmodcnkrn rmjcoqq, od m czmvm oq gzqcjmk. tom madgzqkmmk crq odcoq rtdrdgo dgomzrcmkc mrkzr. m cdk rcq c rkqomz mkmgqcmm tjqkqkrn odcmn rqkc, gkdgo tdqcmkc gqcrzkr. g vgq-kd gmjqkd, om gzrvdc kdotq rcqkm, kqcooq gdv vmmo m oq grcmqk rgmcmkcrn. mqgc mrkdzkm, dgomcgo tdgocmc c qvd dgpnkmnz, rkmjm qcr qiq orcoqq. to qil oq aomqk, gkd rqzgtq gqcrzkm gmcod dkgmod gzrvdcr, tdjkdcr oq gdtrrkmqk corjm, gkd cdcqk tdjrgmkc dkkma. | | 2024-08-05T20:01:20Z |
| BRITANNICA WORLD LANGUAGE DICTIONARY | | 1959 | 2025-08-24T15:43:03Z |