| Title | Description | Published | Added |
| Ep 10 Part 1: Kristine Bunch's Nightmare | In part 1 of this episode, you'll hear about one woman's nightmare come true. In 1995, 21-year-old Kristine Bunch was abruptly awoken in the early morning hours to discover that her house was on fire. After escaping the flames, she watched in horror as firefighters were unable to save her 3-year-old son who was still trapped inside. Within hours of being released from the hospital, she discovered that detectives had a theory about the fire - someone had started the fire on purpose, and their main suspect was Kristine. A special thank you to Kristine Bunch for helping me tell her story.Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie. Music featured in this episode: Like Music (cdk Mix) by cdk (c) copyright 2015 Licensed under a Creative Commons Attribution Share-Alike (3.0) license. htt; | 2016 | 2023-07-08T12:43:39Z |
| Street Fighter Alpha 2 (960430 USA): (BO) Charli1 vs(BR) [CDK]-Shaka - 2022-08-22 01:50:02 | (BO) Charli1 (Rank B) vs (BR) [CDK]-Shaka C - 2022-08-22 01:50:02 Fightcade replay id: 1661133002235-2363 0:00 Charlie vs Ryu 02:06 Charlie vs Guy #fightcade #sfa2u #Charli1 #Ryu #[CDK]-Shaka #0:00:12 #Guy #0:02:06 For more videos check out: https://fightcadevids.com | | 2023-01-23T15:42:07Z |
| Roscovitine confers tumor suppressive effect on therapy-resistant breast tumor cells. | This article is from Breast Cancer Research : BCR , volume 13 . Abstract Introduction: Current clinical strategies for treating hormonal breast cancer involve the use of anti-estrogens that block estrogen receptor (ER)α functions and aromatase inhibitors that decrease local and systemic estrogen production. Both of these strategies improve outcomes for ERα-positive breast cancer patients, however, development of therapy resistance remains a major clinical problem. Divergent molecular pathways have been described for this resistant phenotype and interestingly, the majority of downstream events in these resistance pathways converge upon the modulation of cell cycle regulatory proteins including aberrant activation of cyclin dependent kinase 2 (CDK2). In this study, we examined whether the CDK inhibitor roscovitine confers a tumor suppressive effect on therapy-resistant breast epithelial cells. Methods: Using various in vitro and in vivo assays, we tested the effect of roscovitine on th; | 2011 | 2014-10-28T11:55:39Z |
| Quantifying the CDK inhibitor VMY-1-103's activity and tissue levels in an in vivo tumor model by LC-MS/MS and by MRI. | This article is from Cell Cycle , volume 11 . Abstract The development of new small molecule-based therapeutic drugs requires accurate quantification of drug bioavailability, biological activity and treatment efficacy. Rapidly measuring these endpoints is often hampered by the lack of efficient assay platforms with high sensitivity and specificity. Using an in vivo model system, we report a simple and sensitive liquid chromatography-tandem mass spectrometry assay to quantify the bioavailability of a recently developed novel cyclin-dependent kinase inhibitor VMY-1-103, a purvalanol B-based analog whose biological activity is enhanced via dansylation. We developed a rapid organic phase extraction technique and validated wide and functional VMY-1-103 distribution in various mouse tissues, consistent with its enhanced potency previously observed in a variety of human cancer cell lines. More importantly, in vivo MRI and single voxel proton MR-Spectroscopy further established that VMY-1-103 ; | 2012 | 2014-10-26T21:07:18Z |
| Protein kinase C signaling and cell cycle regulation. | This article is from Frontiers in Immunology , volume 3 . Abstract A link between T cell proliferation and the protein kinase C (PKC) family of serine/threonine kinases has been recognized for about 30 years. However, despite the wealth of information on PKC-mediated control of, T cell activation, understanding of the effects of PKCs on the cell cycle machinery in this cell type remains limited. Studies in other systems have revealed important cell cycle-specific effects of PKC signaling that can either positively or negatively impact proliferation. The outcome of PKC activation is highly context-dependent, with the precise cell cycle target(s) and overall effects determined by the specific isozyme involved, the timing of PKC activation, the cell type, and the signaling environment. Although PKCs can regulate all stages of the cell cycle, they appear to predominantly affect G0/G1 and G2. PKCs can modulate multiple cell cycle regulatory molecules, including cyclins, cyclin-dependent kin; | 2013 | 2014-10-28T20:08:08Z |
| github.com-localstack-localstack_-_2021-11-18_13-41-48 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline! LocalStack provides an easy-to-use test/mocking framework for developing Cloud applications. Overview • Install • Run • Configure • Play – 📖 Docs • 💻 Pro version • ☑️ Feature coverage • 📢 Announcements Overview LocalStack 💻 is a cloud service emulator that runs in a single container on your laptop or in your CI environment.With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider!Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services,LocalStack helps speed up and simplify your testing and development workflow. LocalStack supports a growing number of AWS services, like AWS Lambda, S3, Dynamodb, Kinesis, SQS, SNS, and many more!The Pro version of LocalStack supports additional APIs and advanced features.You c; | 2021 | 2021-11-18T13:56:44Z |
| github.com-sindresorhus-awesome_-_2021-10-02_04-49-15 | 😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab, GitHub, and Bitbucket, Gitpod au; | 2021 | 2021-10-02T15:21:09Z |
| github.com-sindresorhus-awesome_-_2022-01-23_12-29-31 | 😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab, GitHub, and Bitbucket, Gitpod au; | 2022 | 2022-01-23T13:31:49Z |
| github.com-sindresorhus-awesome_-_2023-10-26_15-42-21 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app One Task Stop procrastination and get stuff done by focusing on one task at a time My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. API to get search engine results with ease. API to get search engine results with ease. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Develop; | 2023 | 2023-10-27T01:55:02Z |
| github.com-sindresorhus-awesome_-_2026-03-09_07-59-57 | 😎 Awesome lists about all kinds of interesting topics Check out my macOS app Supercharge Elevate your Mac experience My open source work is supported by the community Special thanks to: Effortless backends with infrastructure from code An open-source framework that supports any programming language, cloud provider, or deployment automation tool. Wispr Flow Talk to code, stay in the Flow. Flow is built for devs who live in their tools. Speak and give more context, get better results. Fast remote container builds and GitHub Actions runners. What is an awesome list? Contribution guide Creating a list Twitter Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Development Environment Entertainment Databases Media Learn Security Content Management Systems Hardware Business Work Networking Decentrali; | 2026 | 2026-03-11T17:33:52Z |
| github.com-DovAmir-awesome-design-patterns_-_2021-07-10_17-58-07 | A curated list of software and architecture related design patterns. Awesome Software and Architectural Design Patterns A curated list of software and architecture related design patterns. Software design pattern - A general, reusable solution to a commonly occurring problem within a given context in software design. It is a description or template for how to solve a problem that can be used in many different situations. Contents Programming language design patterns General Architecture Cloud Architecture Serverless Architecture Micro services & Distributed Systems Internet of things Big Data Databases and storage Docker and DevOps Mobile Front End Development Security Books Programming Language Design Patterns AngularJS design patterns C# design-patterns design-patterns-for-human - ultra simplified explanation to design patterns. Design Patterns Library C++ design-patterns Closure design-patterns Go design-patterns Java sourcemaking - patterns and anti patterns. oodesign - patterns ca; | 2021 | 2021-09-22T22:10:51Z |
| github.com-sindresorhus-awesome_-_2021-12-26_03-21-28 | 😎 Awesome lists about all kinds of interesting topics My macOS app Pandan is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with G; | 2021 | 2021-12-26T22:03:58Z |
| github.com-sindresorhus-awesome_-_2023-05-14_15-35-37 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app Today Quickly view your schedule in the macOS menu bar My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Build Scalable Feeds & Chat Applications with Powerful APIs and Front End Components Build Scalable Feeds & Chat Applications with Powerful APIs and Front End Components Paperwork that makes the data work. Easy APIs for paperwork. PDF generation, e-signature and embeddable no-code webforms. The easiest way to build paperwork automation into your product. Paperwork that makes the data work. E; | 2023 | 2023-05-14T17:50:28Z |
| github.com-sindresorhus-awesome_-_2023-10-24_23-57-20 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app One Task Stop procrastination and get stuff done by focusing on one task at a time My open source work is supported by the community Special thanks to: Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. API to get search engine results with ease. API to get search engine results with ease. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Develop; | 2023 | 2023-10-25T11:07:00Z |
| github.com-sindresorhus-awesome_-_2022-01-21_21-53-36 | 😎 Awesome lists about all kinds of interesting topics My Actions app is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab; | 2022 | 2022-01-22T00:52:52Z |
| Cell cycle control : mechanisms and control | xii, 402 p. : 24 cm // Includes bibliographical references and index // Cell cycle molecules and mechanisms of the budding and fission yeasts / Tim Humphrey and Amanda Pearce -- The plant cell cycle : an overview / John H. Doonan -- The C. elegans cell cycle / Sander van den Heuvel -- Developmental control of growth and cell cycle progression in drosophila / Lisa Swanhart, Jeremy Kupsco, and Robert J. Duronio -- The xenopus cell cycle : an overview / Anna Philpott and P. Renee Yew -- The mammalian cell cycle : an overview / Jane V. Harper and Gavin Brooks -- Synchronization of cell populations in G1/S and G2/M phases of the cell cycle / Jane V. Harper -- Mapping origins of DNA replication in eukaryotes / Susan A. Gerbi -- In situ assay for analyzing the chromatin binding of proteins in fission yeast / Stephen E. Kearsey ... [et al.] -- Application of magnetic beads to purify cells transiently transfected with plasmids encoding short hairpin RNAs / Peter D. Adams -- The cell cycle and v; | 2005 | 2020-05-25T23:53:12Z |
| Predict shipment ETA with no-code machine learning using Amazon SageMaker Canvas | Over the last few years, online education platforms have seen an increase in adoption of and an uptick in demand for video-based learnings because it offers an effective medium to engage learners. To expand to international markets and address a culturally and linguistically diverse population, businesses are also looking at diversifying their learning offerings by localizing content into multiple languages. These businesses are looking for reliable and cost-effective ways to solve their localization use cases. Localizing content mainly includes translating original voices into new languages and adding visual aids such as subtitles. Traditionally, this process is cost-prohibitive, manual, and takes a lot of time, including working with localization specialists. With the power of AWS machine learning (ML) services such as Amazon Transcribe , Amazon Translate , and Amazon Polly , you can create a viable and a cost-effective localization solution. You can use Amazon Transcribe to create a; | 2022 | 2022-08-10T05:07:03Z |
| Cell cycle control : mechanisms and protocols | Includes bibliographical references and index // Cell cycle molecules and mechanisms of the budding and fission yeasts / Tim Humphrey and Amanda Pearce -- The plant cell cycle / John H. Doonan -- The C. elegans cell cycle / Sander van den Heuvel -- Developmental control of growth and cell cycle progression in drosophila / Lisa Swanhart, Jeremy Kupsco, and Robert J. Duronio -- The xenopus cell cycle / Anna Philpott and P. Renee Yew -- The mammalian cell cycle / Jane Vera Harper and Gavin Brooks -- Synchronization of cell populations in G1/S and G2/M phases of the cell cycle / Jane Vera Harper -- Mapping origins of DNA replication in eukaryotes / Susan A. Gerbi -- In situ assay for analyzing the chromatin binding of proteins in fission yeast / Stephen E. Kearsey ... [et al.] -- Application of magnetic beads to purify cells transiently transfected with plasmids encoding short hairpin RNAs / Peter D. Adams -- The cell cycle and virus infection / Steven Emmett ... [et al.] --^ // Methods fo; | 2005 | 2012-05-22T14:15:36Z |
| Behind The Scenes and Updates On Each Case | In this episode, I take you behind-the-scenes of each case I covered in the Court Junkie podcast, as well as go over the latest updates. You'll also hear from Pravin Varughese's mom and family friend, as well as other Court Junkies. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie.Music featured in this episode: - Improvisation On Friday... by Alex (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/AlexBeroza/17253 Ft: The3amAssociation - CAliformia Road by dilating_times (c) copyright 2014 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/dilating_times/44880 - summertime instrumental 1 by cdk (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter; | 2017 | 2023-07-08T12:41:02Z |
| Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks. | This article is from BMC Systems Biology , volume 6 . Abstract Background: High-throughput measurement technologies produce data sets that have the potential to elucidate the biological impact of disease, drug treatment, and environmental agents on humans. The scientific community faces an ongoing challenge in the analysis of these rich data sources to more accurately characterize biological processes that have been perturbed at the mechanistic level. Here, a new approach is built on previous methodologies in which high-throughput data was interpreted using prior biological knowledge of cause and effect relationships. These relationships are structured into network models that describe specific biological processes, such as inflammatory signaling or cell cycle progression. This enables quantitative assessment of network perturbation in response to a given stimulus. Results: Four complementary methods were devised to quantify treatment-induced activity changes in processes described by ; | 2012 | 2014-10-25T01:34:45Z |
| CIA Reading Room cia-rdp70-00058r000200100098-1: PUZZLING FOREIGN POLICY OF THE U.S. | FE.B. 1 51962 Approved For Release 1999/09/'-pQ1 .RDP7 United 8tates'T e ro ruby die has rdad in. hiai iodal ,which goes MO A,maxrlcan w psper. head-- haq~_ Cominunlat lined' :"Vtl~ e d ti 4!- .,stay' cra* e iA- OOMDgiW11'k .. Cdk ? bif thin M4 Ctrants: : thy; ''zi ,e4 tent to foreigh.*ld' anti the Congo Leader:' it erptains ywQ s trong atfr pe Vol" of,A oa Yet the "iJnlt d gat- ' t d f th o re e e o .policies which go along with former . Batista government this vast pone, do. Tf a c$dl 1'9 goal di et .4 Yr t 1 1e pt Victory' )endue B +dk a ltfiil Q d ve tIs at gC'tbe ' muiifng ta11i fir .. < ;thd words et etc. have speeches ' men. _~ e "l ode ?tSat~ snatchesf h p_oeeibie' 14%, Dim kTuubaff~ ~*ent-in the T?os rte 's, the l" rnm #? ant i~ic tltt~aoty.. Vital, i o s e a slat t[1gli,~ ? f i'q~M,' Cato ndgixe ex+~ e s 1$ o bf t 1+ . 'e dl 'iral o 1, + # < Uride*rstar-dstr,~ Ikrta eager ~e~ e td l t ' :thew le' n logs ,tn ezontinq otii rj~Y .# tiYea rioltcy a it izas ttt-t era:.+1e tie; era; | 1962 | 2023-08-06T09:52:48Z |
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| Plant WEE1 kinase is cell cycle regulated and removed at mitosis via the 26S proteasome machinery. | This article is from Journal of Experimental Botany , volume 64 . Abstract In yeasts and animals, premature entry into mitosis is prevented by the inhibitory phosphorylation of cyclin-dependent kinase (CDK) by WEE1 kinase, and, at mitosis, WEE1 protein is removed through the action of the 26S proteasome. Although in higher plants WEE1 function has been confirmed in the DNA replication checkpoint, Arabidopsis wee1 insertion mutants grow normally, and a role for the protein in the G2/M transition during an unperturbed plant cell cycle is yet to be confirmed. Here data are presented showing that the inhibitory effect of WEE1 on CDK activity in tobacco BY-2 cell cultures is cell cycle regulated independently of the DNA replication checkpoint: it is high during S-phase but drops as cells traverse G2 and enter mitosis. To investigate this mechanism further, a yeast two-hybrid screen was undertaken to identify proteins interacting with Arabidopsis WEE1. Three F-box proteins and a subunit of t; | 2013 | 2014-10-23T22:24:00Z |
| github.com-sindresorhus-awesome_-_2021-11-30_06-23-08 | 😎 Awesome lists about all kinds of interesting topics My macOS app Pandan is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with G; | 2021 | 2021-11-30T06:30:59Z |
| github.com-sindresorhus-awesome_-_2022-08-11_12-20-41 | 😎 Awesome lists about all kinds of interesting topics Check out: One Thing — Put a single task or goal in your menu bar My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the clo; | 2022 | 2022-08-18T11:22:09Z |
| github.com-sindresorhus-awesome_-_2022-11-14_11-14-47 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app Favorites Widget Call your favorite people directly from the iPhone Lock Screen My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing u; | 2022 | 2022-11-14T21:57:22Z |
| High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a. | This article is from Microbiology , volume 158 . Abstract The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry. The rapid increase of resistance to therapeutic agents, as well as the expense of vaccination with live attenuated vaccines, requires the development of new effective treatments for coccidiosis. Because of their key regulatory function in the eukaryotic cell cycle, cyclin-dependent kinases (CDKs) are prominent drug targets. The Eimeria tenella CDC2-related kinase 2 (EtCRK2) is a validated drug target that can be activated in vitro by the CDK activator XlRINGO (Xenopus laevisrapid inducer of G2/M progression in oocytes). Bioinformatics analyses revealed four putative E. tenella cyclins (EtCYCs) that are closely related to cyclins found in the human apicomplexan parasite Plasmodium falciparum. EtCYC3a was cloned, expressed in Escherichia coli and purified in a co; | 2012 | 2014-10-28T23:41:32Z |
| github.com-sottlmarek-DevSecOps_-_2022-01-15_03-45-55 | Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevSecOps scope. Table of Contents Def; | 2022 | 2022-01-15T10:00:54Z |
| Macintosh Mania 1 | | | 2019-07-06T06:46:50Z |
| github.com-serverless-stack-serverless-stack_-_2022-02-03_19-01-38 | 💥 SST makes it easy to build serverless apps. Set breakpoints and test your functions locally. https://serverless-stack.com Serverless Stack (SST) is a framework that makes it easy to build serverless apps. It's an extension of AWS CDK and it features: A Live Lambda Development environment Support for setting breakpoints and debugging in VS Code Support for deploying to multiple environments and regions Higher-level constructs designed specifically for serverless apps Zero-config support for JS and TS (using esbuild ), Go, Python, C#, and F# Quick Start Create your first SST app. ```bash Create your app $ npx create-serverless-stack@latest my-sst-app$ cd my-sst-app Start Live Lambda Development $ npx sst start Deploy to prod $ npx sst deploy --stage prod``` Documentation SST docs SST examples Public roadmap Feature requests Contributing to SST Follow us on Twitter and subscribe to our newsletter for updates. About SST We think SST can make it dramatically easier to build serverless ; | 2022 | 2022-02-04T20:51:28Z |
| github.com-sindresorhus-awesome_-_2022-01-21_04-06-07 | 😎 Awesome lists about all kinds of interesting topics My Actions app is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with GitLab; | 2022 | 2022-01-21T12:39:20Z |
| github.com-sindresorhus-awesome_-_2021-04-23_16-56-34 | 😎 Awesome lists about all kinds of interesting topics My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. What is an awesome list? Contribution guide Creating a list Twitter Stickers & t-shirts Follow the Awesome Twitter account for updates on new list additions. Just type awesome.re to go here. Check out my blog and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Development Environment Entertainment Databases Media Learn Security Content Management Systems Hardware Business Work Networking Decentralized Systems Higher Education Events Testing Miscellaneous Related Platforms Node.js - Async non-blocking event-driven JavaScript ru; | 2021 | 2021-04-25T20:56:24Z |
| Flourescent Protein Tracing | | 1962 | 2025-09-12T10:44:29Z |
| Cyclin D1 inhibits whereas c-Myc enhances the cytotoxicity of cisplatin in mouse pancreatic cancer cells via regulation of several members of the NF-?B and Bcl-2 families. | This article is from Journal of Carcinogenesis , volume 10 . Abstract Background:: Cisplatin (CDDP) is a drug used for treatment of many types of malignancy but pancreatic cancer is relatively resistant to it. This study aims to determine whether and how cyclin D1 (D1) and c-Myc influence the response of pancreatic cancer cells to CDDP. Materials and Methods:: Ela-mycPT mouse pancreatic cancer cells were transfected with D1 or c-myc cDNA and treated with CDDP alone or together with NPCD, an inhibitor of cyclin dependent ckinase (CDK) 4 and 6. Reverse transcription followed by polymerase chain reaction (RT-PCR) and western blot assays were used to determine the mRNA and protein levels of interested genes. Cell viability was determined using 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. Results:: Treatment of Ela-mycPT1 cells with CDDP caused an increase in c-myc expression but a slightly latent decrease in D1 expression, whereas D1 and c-Myc proteins repres; | 2011 | 2014-10-28T18:52:34Z |
| github.com-lloesche-valheim-server-docker_-_2021-03-12_08-25-55 | Valheim dedicated gameserver with automatic update, World backup and ValheimPlus mod support lloesche/valheim-server Docker image Valheim Server in a Docker Container (with ValheimPlus support) Table of contents Basic Docker Usage Environment Variables Log filters Event hooks Event hook examples Install extra packages Copy backups to another location Delay restarts by 1 minute and notify on Discord ValheimPlus config from Environment Variables System requirements Deployment Deploying with Docker and systemd Deploying with docker-compose Deploying to Kubernetes Deploying to AWS ECS Updates Backups Finding Your Server In-game Steam Server Browser Steam Server Favorites & LAN Play Admin Commands Supervisor Supervisor API Status web server ValheimPlus Updates Configuration Server data rate Disable server password Changing startup CMD in Portainer Synology Help First install Updating the container image to the latest version Error after download of new container image Basic Docker Usage The; | 2021 | 2021-03-15T19:02:56Z |
| github.com-sindresorhus-awesome_-_2021-12-31_20-40-33 | 😎 Awesome lists about all kinds of interesting topics My macOS app Pandan is on Product Hunt My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing up Dev environments built for the cloud Natively integrated with G; | 2021 | 2022-01-01T00:48:30Z |
| github.com-sindresorhus-awesome_-_2022-11-22_17-54-05 | 😎 Awesome lists about all kinds of interesting topics Check out my latest app Favorites Widget Call your favorite people directly from the iPhone Lock Screen My open source work is supported by the community Special thanks to: All your environment variables, in one place Stop struggling with scattered API keys, hacking together home-brewed tools, and avoiding access controls. Keep your team and servers in sync with Doppler. Your app, enterprise-ready. Start selling to enterprise customers with just a few lines of code. Add Single Sign-On (and more) in minutes instead of months. Strapi is the leading open-source headless CMS. It’s 100% JavaScript, fully customizable, and developer-first. Founded in 2018, OSS Capital is the first and only venture capital platform focused exclusively on supporting early-stage COSS (commercial open source) startup founders. Instant, shareable cloud PostgreSQL database Import any dataset in seconds, share with anyone with a click, try without signing u; | 2022 | 2022-11-23T13:49:19Z |
| github.com-sindresorhus-awesome_-_2025-07-18_18-37-33 | 😎 Awesome lists about all kinds of interesting topics Check out my macOS app Supercharge Elevate your Mac experience My open source work is supported by the community Special thanks to: Effortless backends with infrastructure from code An open-source framework that supports any programming language, cloud provider, or deployment automation tool. What is an awesome list? Contribution guide Creating a list Twitter Just type awesome.re to go here. Check out my apps and follow me on Twitter . Contents Platforms Programming Languages Front-End Development Back-End Development Computer Science Big Data Theory Books Editors Gaming Development Environment Entertainment Databases Media Learn Security Content Management Systems Hardware Business Work Networking Decentralized Systems Health and Social Science Events Testing Miscellaneous Related Platforms Node.js - Async non-blocking event-driven JavaScript runtime built on Chrome's V8 JavaScript engine. Cross-Platf; | 2025 | 2025-09-12T02:09:36Z |
| github.com-sottlmarek-DevSecOps_-_2022-05-25_08-16-15 | Ultimate DevSecOps library Ultimate DevSecOps library Contribution rules If you want to contribute to this library of knowledge please create proper PR (Pull Request) with description what you are adding following these set of rules: Clear description of PR (which tool, why, number of stars, maturity and topic) Keep it simple - Fill the description properly Fact over feelings or personal opinions Add source and follow the library style Avoid duplicits - one tool, one topic Try to make bigger updates then on tool link Currently open-source only Add only active projects Add only security tools Report typos as issue not via PR. Note: Currently this is an early version of the library. I recommend PR after first official release. DevSecOps library info: This library contains list of tools and methodologies accompanied with resources. The main goal is to provide to the engineers a guide through opensource DevSecOps tooling. This repository covers only cyber security in the cloud and the DevS; | 2022 | 2022-06-01T22:17:36Z |
| Hobbes OS2 September 1999 Walnut Creek CD | Hobbes OS2 September 1999 Walnut Creek CD | 1999 | 2023-06-09T14:45:28Z |
| CIA Reading Room cia-rdp91-00772r000301760021-8: A FR: KOKUBO-KEIZAI, TSUSHIN TO: KOMMERCHESKIY, VESTNIK | Deff)')V) Agencyls Fiscal Year 197L4 Budget,(TOVT'1 7 I)p.SIRNMENT rjsl!,., ONLY,F -H, 'L,r0 1% .3 0 IZAI TSUSHIN, Tokyo, 23 Jan 7,u -.ZipJPIRS/L 41832Mar 71.1.11 ,.r], -;-~ 1~ -]HKO 'AV I.M.W. ifo =mm//LOW 1"PA(lelOp kitenna for, the Tokyo-lbarrid14f.crOw e fjolay Route,Mald "'olik-'buro Nember Ass,31sses PoliticalSitur.,,tlo-a, I-py E-liyahu Drulman, 10 T)p.HEBRITJ, nov, ",*ol Haam, Aviv, 7 Feb 73,P'o 10-11, ll~.-.1J,?R's, 5&.-LIr 7 3I-ICIo 1 -za anCoin-nrixaise)rol)lllr,a, LrY--IAclvocated to '3ett.l-- I'alesLinianWit La`a,-tv, 9 pr'.-.cl -alpin, Avi%r,IIL - -ar 73,ic~ yt remi s c rrl c j- !"ireas-ellLlus - u -11j.4,y OfbY Y(Aluda Lah.ev.-3: 1 EDI0 1 T,a LviV73,Aor 731" p T~ eo, a,.! ee a r a sI-jl:) ,oTY!"ofby'')taff 7)jSC- SSC.Solua Lahav,I r10junLahav., YehudaBedouin 3i.ipj,)o:*qteis Predict New CivilianEx-oulsions in Sinai, 10 pp.KOL HAIM, Aviv, 25 Jul 73, -.-jp 10. 1.!.JPRS 7-77,7Oc t 7.1,4m,q 11,ational convention for Tokodl List,5r-op .M IIA IAM,, Tel Aviv, 1 Aug 73, p 2.ip I; | 1983 | 2026-03-24T11:09:31Z |
| Barts Installer #14 - Super Language Collection | Looking for old abandonware warez CD ISO's - If you have any not in my collection please contact me (pascal_of_irate @ hotmail . com). I can remove any copy protections from them (if required) and repost cracked versions for the community to enjoy. I am especially interested in CD's from the likes of Blobby International, Playdoh, Voodoo, Ghost, Tango, Delta, USA, Gold, Redhot, Jurassic, Pepsi, Alkey, Capaccino, Coke, Total, Razor, Xenon etc. but also any others from this era. Please see our special requests as the bottom of this page. BART`s INSTALLER 14 SUPER LANGUAGE COLLECTION BC50 [DIR] BORLAND C++ V5.0 DEVELOPERS SUITE COBOL [DIR] MS COBOL V4.5 CPU_CTL [DIR] SPECIAL COLLECTION FOR ELECTRONIC HOBBISTS DELPHI20 95 [DIR] BORLAND DELPHI 2.0 DEVELOPERS SUITE FORTH [DIR] FORTH V2.0 FORTRAN [DIR] MS FORTRAN V5.1 FOXLIB26 [DIR] MS FOXPRO 2.6 LIBRARY CDK FOXPODBC [DIR] MS FOXPRO 2.6 ODBC FOXPRO26 DOS [DIR] MS FOXPRO 2.6 FOR DOS MASM6 [DIR] MS MACRO ASSEMBLER 6.0 MSC70 [DIR] MS C/C++ V7.0 ; | | 2019-11-09T21:22:32Z |
| ＰＨＯＮＫ ＦＲＩＤＡＹＳ | iNFMS - The Don Chronicles pt.1 | PHONK FRIDAY SEASON 3 | Episode 1 --------------------------------------------------------------- Produced by iNFMS | https://infms495.bandcamp.com/ Video Edit by iNFMS chapter 3: 𝖙𝖍𝖊 𝖉𝖔𝖓 𝖈𝖍𝖗𝖔𝖓𝖎𝖈𝖑𝖊𝖘 - [00:20] MAKE SOME ENDZ [03:14] SHE DONT EVEN SMOKE [06:23] ADRENOCHROME [09:48] ADRENOCHROME PT 2 [11:49] 200 THOUSAND ON MY WRIST [15:07] $CREWED UP [17:34] SMOKIN OUT - -special thanks: LORDKADO, STVSHBOI, PXSSXSSXD, BADRADIO and ANALOG BY NATURE - -audio drip: https://soundcloud.com/iaminfms/the-don-chronicles-vol-1 - https://www.analogbynature.tv https://www.badradio.nz Twitter - twitter.com/official_iNFMS Twitch - twitch.tv/analogbynature DLive - https://dlive.tv/cdk - Official Spotify Playlist: https://spoti.fi/2V5Jzqr Join : https://bit.ly/2UIIw08 ▶▶ATTENTION ARTISTS AND PRODUCERS▶▶ ----Submissions: http://bitSubmit.net/21 ---100% Free Music Distribution on spotify , itunes , and more http://www.amuse.io?utm_source=RC ▶▶Co; | 2020 | 2024-02-12T06:19:34Z |
| Ep 10 Part 2: Kristine Bunch's Struggle For Freedom | In Part 2 of this episode, Kristine and her newly-formed defense team fight to win back her freedom. Armed with advances in fire science, a potential Brady violation, and some shocking revelations about the State's evidence at trial, Kristine and her team fight till the very end. A special thank you to Kristine Bunch for helping me tell her story. Please consider supporting Court Junkie with as little as $3 a month via Patreon.com/CourtJunkie. Help support Court Junkie with $6 a month and get access to bonus monthly episodes.Follow me on Twitter @CourtJunkiePod or Instagram at CourtJunkie. Music featured in this episode: Like Music (cdk Mix) by cdk (c) copyright 2015 Licensed under a Creative Commons Attribution Share-Alike (3.0) license. http://dig.ccmixter.org/files/cdk/48915 Ft: Phasenwandler Homesick (Keymix) by keytronic (c) copyright 2014 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/Keytronic/47457 Ft: Kizzylotus Paper Planes - Durd; | 2016 | 2023-07-08T12:43:12Z |
| Teaching and Learning Adolescent Psychiatry | | 1971 | 2025-09-26T19:28:34Z |
| Remarkable women of france ( from 1431 to 1749 ) | | 1914 | 2025-09-08T04:07:29Z |
| Het Utrechts Archief 168793 | Het Utrechts Archief catalog number: 168793 Description (Dutch): Afbeelding van een gezelschap op het 4e perron van het N.S.-station Rotterdam C.S. te Rotterdam, bij het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het betreft hier een gezelschap uit een extra trein voor de Handelsmaatschappij R.S. Stokvis en Zonen. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610). | 1961 | 2021-02-03T11:11:51Z |
| github.com-localstack-localstack_-_2022-08-19_18-22-53 | 💻 A fully functional local AWS cloud stack. Develop and test your cloud & Serverless apps offline! LocalStack provides an easy-to-use test/mocking framework for developing Cloud applications. Overview • Install • Example • Run • Usage • Changelog • Contributing – 📖 Docs • 💻 Pro version • ☑️ Feature coverage • 📢 Announcements Overview LocalStack 💻 is a cloud service emulator that runs in a single container on your laptop or in your CI environment. With LocalStack, you can run your AWS applications or Lambdas entirely on your local machine without connecting to a remote cloud provider! Whether you are testing complex CDK applications or Terraform configurations, or just beginning to learn about AWS services, LocalStack helps speed up and simplify your testing and development workflow. LocalStack supports a growing number of AWS services, like AWS Lambda, S3, Dynamodb, Kinesis, SQS, SNS, and many more! The Pro version of LocalStack supports additiona; | 2022 | 2022-08-20T01:25:04Z |
| github.com-T-head-Semi-wujian100_open_-_2019-10-24_06-20-55 | IC design and development should be faster，simpler and more reliable wujian100_open wujian100_open is a MCU base SoC. We can simulate by EDA tools and emulate by FPGA. Also we can develop the IPs and software in this platform. We wish more and more developers building the open MCU ecosystem with T-Head. IC design and development should be faster simpler and more reliableDirectory Structure|--Project //open source project work directory |--riscv_toolchain //tool chain install directory download from t-head.cn |--wujian100_open //wujian100_open project get from github |--case //test case example for simulation |--doc //wujian100_open user guide |--fpga //FPGA script |--lib //compile script for simulation |--regress //regression result |--sdk //software design kit |--soc //Soc RTL source code |--tb //test bench |--tools //simulation script and setup file |--workdir //simulation directory |--LICENSE |--README.md Get Start 1. prepare a project work directory just like 'Project'2. cd Proje; | 2019 | 2019-10-24T09:00:18Z |
| Het Utrechts Archief 168792 | Het Utrechts Archief catalog number: 168792 Description (Dutch): Afbeelding van een gezelschap op het 4e perron van het N.S.-station Rotterdam C.S. te Rotterdam, bij het electrische treinstel nr. 461 (mat. 1936) van de N.S.N.B. Het betreft hier een gezelschap uit een extra trein voor de Handelsmaatschappij R.S. Stokvis en Zonen. Het treinstel 461 was een electrisch drierijtuigen-treinstel dat na de oorlog is samengesteld uit bakken van diverse treinstellen (Bk 607, C 613 en CDk 610). | 1961 | 2021-02-05T03:16:03Z |