| Title | Description | Published | Added |
| The role of ?-adrenergic receptor signaling in the proliferation of hemangioma-derived endothelial cells. | This article is from Cell Division , volume 8 . Abstract Background: Infantile hemangioma (IH) is a benign vascular neoplasm that arises from the abnormal proliferation of endothelial cells and enhanced angiogenesis. Recently, propranolol has been found to be effective in the management of IH, suggesting that β-adrenergic receptors (β-ARs) may play an important role in the pathogenesis of IH. Results: In the present study, we investigated the β-adrenergic signaling that is associated with hemangioma-derived endothelial cell (HemEC) proliferation. The results showed that both β1- and β2-ARs were expressed in HemECs. Stimulation of the β-ARs by isoprenaline induced cell proliferation and elevation of second messenger cAMP levels. The proliferation-promoting action of isoprenaline was abolished by a β1-selective antagonist and was more effectively abolished by a β2-selective antagonist; the mechanism for the action of the antagonists was a G0/G1 phase cell cycle arrest which was a; | 2013 | 2014-10-29T13:12:50Z |
| CIA Reading Room cia-rdp75-00149r000500450023-6: MR. KENNEDY AND THE CUBA BRIEFING | STAT Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 25 YEAR RF. RFviFXnil Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 STAT F-a d STAT " Mr. Kennedy. and the CubaBriefin V~~r~ ql cdk Otl,ar MAK Sanitized Copy Approved for Release 2010/04/09: CIA-RDP75-00149R000500450023-6 i liu,b,2 Pres1&nt .Kennedy's con- tention that he was not, in- formed during the 1960 cam- paign that the Eisenhower administration was sponsor- ing training of Cubans for a possible later invasion to at- tempt to overthrow Castro is one of the most astonish- ing announcements to come ;role the White House under any President in many years. - The President contends that he was not told of the training of Cubans in the U.S. until after he was elect- ed. He carried out the in- vasion under. his own plan- ning after becoming Presi- dent -- in a, manner that Mr. Kennedy's contention was made public by his Chief Press Secretary, Pierre Sal- inger, in respon; | 1962 | 2025-05-16T03:48:08Z |
| CIA Reading Room cia-rdp79-01209a000400060001-9: Weekly Situation Report on International Terrorism | Sanitized - Approved For Release : CIA-RDP79-01209A000400060001-9 No em Abroad Co oiled Dissem Weekly Situation Report on into tional Terrorism Sanitized - Approved For Release : CIA-RDP79-01209A000400060001-9----~ Sanitized - Approved For Release : CIA-RDP79-01209A000400060001-925X1 C3b2 Next 6 Page(s) In Document Exempt Sanitized - Approved For Release : CIA-RDP79-01209A000400060001-9 Sanitized - Approved For Release : CIA-RDP79-01209A000400060001-9 SE NOTES Khartoum BSO Terrorists Imprisoned in Egypt The eight Black September Organization terrorists con- victed of murdering two U.S. diplomats and the Belgian Charge d'Affaires in Khartoum in. March 1973 are currently in an Egyp- tian prison, according to the State Department. The eight, sentenced to life imprisonment on 24 June by a Khartoum court, had their terms reduced by Sudanese President Numayri and were reportedly to be turned over to the Palestine Liberation Organi- zation (PLO) to serve seven-year sentences. According to pre; | 1974 | 2023-06-26T22:33:05Z |
| Dedos De Oro | Tracklist: 1. El Dedos De Oro - Teodoro Bello 2. El Ojo De Agua - Mario Quintero L. 3. Nieve De Sabores - Alfredo Araujo 4. Compra Y Venta - Jose Ontiveros M. 5. No Necesito De Claves - Jose Ontiveros M. 6. Soy De La Tierra De Villa - Carlos Ventura 7. El Primo - Mario Quintero L. 8. La Fuga Del Zorro - Teodoro Bello 9. La Fiera De Michoacan - Efren Avila 10. Las Novias Del Traficante - Francisco Quintero O. 11. De Tierra Pobre 12. Boda De Sangre - Teodoro Bello | 2002 | 2025-04-10T03:30:33Z |
| CIA Reading Room cia-rdp70-00058r000200100098-1: PUZZLING FOREIGN POLICY OF THE U.S. | FE.B. 1 51962 Approved For Release 1999/09/'-pQ1 .RDP7 United 8tates'T e ro ruby die has rdad in. hiai iodal ,which goes MO A,maxrlcan w psper. head-- haq~_ Cominunlat lined' :"Vtl~ e d ti 4!- .,stay' cra* e iA- OOMDgiW11'k .. Cdk ? bif thin M4 Ctrants: : thy; ''zi ,e4 tent to foreigh.*ld' anti the Congo Leader:' it erptains ywQ s trong atfr pe Vol" of,A oa Yet the "iJnlt d gat- ' t d f th o re e e o .policies which go along with former . Batista government this vast pone, do. Tf a c$dl 1'9 goal di et .4 Yr t 1 1e pt Victory' )endue B +dk a ltfiil Q d ve tIs at gC'tbe ' muiifng ta11i fir .. < ;thd words et etc. have speeches ' men. _~ e "l ode ?tSat~ snatchesf h p_oeeibie' 14%, Dim kTuubaff~ ~*ent-in the T?os rte 's, the l" rnm #? ant i~ic tltt~aoty.. Vital, i o s e a slat t[1gli,~ ? f i'q~M,' Cato ndgixe ex+~ e s 1$ o bf t 1+ . 'e dl 'iral o 1, + # < Uride*rstar-dstr,~ Ikrta eager ~e~ e td l t ' :thew le' n logs ,tn ezontinq otii rj~Y .# tiYea rioltcy a it izas ttt-t era:.+1e tie; era; | 1962 | 2023-08-06T09:52:48Z |
| Hobbes OS2 September 1999 Walnut Creek CD | Hobbes OS2 September 1999 Walnut Creek CD | 1999 | 2023-06-09T14:45:28Z |
| github.com-dabit3-awesome-aws-amplify_-_2021-02-13_23-48-59 | Curated list of AWS Amplify Resources Awesome AWS Amplify curates the best AWS Amplify, tools, tutorials, articles and more. PRs are welcome! Check out the Amplify Discord server Getting Started Github Documentation Workshops Serverless GraphQL API with AppSync and DynamoDB AWS Amplify Photo Sharing Workshop Next.js AWS Amplify Workshop Building real-time applications with React, GraphQL & AWS AppSync Building Mobile Applications with React Native & AWS Amplify AWS Amplify UnicornFlix Workshop (Video on Demand) AWS Amplify UnicornTrivia Workshop (Live streaming video) Tutorials - Blogs & tutorials General blogs & tutorials Full Stack Cloud Development with AWS Amplify TensorFlow.js + AWS Amplify 10 Minute Tutorial: Creating a Serverless Express Web Server & API ⚡️ 10 Ways to Use Serverless Functions Real quick GraphQL service with AWS Amplify & Appsync Visualizing Focus with Neurosity's Notion and AWS Amplify Build a Music Sharing App with Amazon S3 and AWS Amplify Introducing Conf; | 2021 | 2021-02-22T13:28:20Z |
| The King of Fighters 2002: (AR) -Arles-*CBZ* vs(BR) [CDK]-Shaka - 2021-10-08 07:37:40 | (AR) -Arles-*CBZ* vs (BR) [CDK]-Shaka - 2021-10-08 07:37:40 Fightcade replay id: 1633678660240-6729 #fightcade #kof2002 #-Arles-*CBZ* #[CDK]-Shaka For more videos check out: https://fightcadevids.com | | 2023-01-21T21:28:01Z |
| DTIC ADA415662: Interactions Between Cell Cycle Control Proteins and the Androgen Receptor in Prostate Cancer | This project is based on our discovery that cyclin dependent kinase 6 (CDK6) can markedly stimulate the transcriptional activity of the androgen receptor (AR) in human prostate cancer cells. The research performed during the past year has confirmed and extended these findings and provided insights into the underlying mechanisms. Thus, we found that CDK6 can physically associate with the AR in vivo. Using a series of truncated and mutant forms of CDK6 that we constructed we obtained evidence that the cyclin Dl binding domain and the ATP binding site in CDK6 are not essential for the stimulatory effect of CDK6 on the AR. These results, taken together with additional findings, indicate that CDK6 can bind to and directly stimulate the activity of the AR via a cyclin Dl and kinase independent mechanism. Therefore, in addition to its role in cell cycle control, CDK6 may play an independent role in modulating the activity of the AR. Our findings may have clinical significance since they sugge; | 2003 | 2018-05-13T16:32:13Z |
| CIA Reading Room cia-rdp79-01209a000300030001-3: Weekly Situation Report on International Terrorism | Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 No For Dissem No sem Abroad ontrolled Dissem Weekly Situation Report on International Terrorism 7 November 1973 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300g30D.0.1.:_3.-.-.- -, .a 25X1 C3b2 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Next 11 Page(s) In Document Exempt Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 25X1 C3b2 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Approved For Release 1999/09/21 : CIA-RDP79-01209A000300030001-3 Approved For Release 1999/09/21 : CIA-RP? @fn9AO00300030001-3 No Fore'ici.n Dissem/N sem ~Abrocrd/Controlled :Dissem he presumably smuggled aboard,the aircraft in Maracaibo. The hijacker, who is in critical' Condition and not expected to live, apparently wanted to fly to Cuba to live with his par; | 1973 | 2023-06-26T23:01:38Z |
| CIA Reading Room cia-rdp83m00914r002300100097-4: PUBLICATION OF UNCLASSIFIED ANALYSIS | Approved For Release 2007/03/09: CIA-RDP83MOO914R002300100097-4 .xcacutlve Rayic4ig FEB 17 4 05 P4 ?8L MEMORANDUM FOR: Director of Central Intelligence OEXA 82-0455/1 17 FEB 1982 Director, ice o External Affairs SUBJECT: Publication of Unclassified Analysis 1. Action. Requested: Sign the attached letter to Gustav F. Papanek, Boston University, President of the Association for .Comparative Economic Studies. 2. Background: Pananek wrote you on 5 February 1982 to ask that you resume release of unclassified. CIA analysis to the public. (Tab A) The attached proposed response is consistent with your 20 January 1982 letter to Messrs. Becker and Horelick at the.Rand Corporation, and a more recent letter Bob Gates sent to Dr. Grossman of the University.of California on the same subject. (Tab B) It has been adjusted to avoid the look of a form letter, however, since it is likely that these people exchange letters with each other. 3. Recommendation: Sign the attached letter. U -:, Ui1- Director o; | 1982 | 2025-02-22T15:23:14Z |